PMC:7247521 / 1197-1541 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"31","span":{"begin":59,"end":63},"obj":"Gene"},{"id":"38","span":{"begin":219,"end":224},"obj":"Chemical"},{"id":"44","span":{"begin":45,"end":54},"obj":"Disease"}],"attributes":[{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"Gene:59272"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T26","span":{"begin":59,"end":63},"obj":"G_3;PG_10;PR:000003622"},{"id":"T27","span":{"begin":67,"end":77},"obj":"GO:0010467"},{"id":"T28","span":{"begin":252,"end":261},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T29","span":{"begin":316,"end":320},"obj":"CHEBI:23888;CHEBI:23888"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2","span":{"begin":78,"end":86},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T9","span":{"begin":45,"end":54},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T9","span":{"begin":186,"end":192},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T10","span":{"begin":330,"end":334},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T6","span":{"begin":78,"end":86},"obj":"Chemical"},{"id":"T7","span":{"begin":316,"end":320},"obj":"Chemical"}],"attributes":[{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":45,"end":54},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}

{"project":"LitCovid-sentences","denotations":[{"id":"T14","span":{"begin":88,"end":205},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ed 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins. Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients. In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high"}