PMC:7247521 / 10599-11509 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
176	330-334	Gene	denotes	Mpro	Gene:8673700
177	350-354	Gene	denotes	RdRp	Gene:43740578
178	373-377	Gene	denotes	RdRp	Gene:43740578
179	399-407	Gene	denotes	Helicase	Gene:164045
180	426-434	Gene	denotes	Helicase	Gene:164045
181	336-341	Gene	denotes	PLpro	Gene:43740578
182	111-115	Species	denotes	ncov	Tax:2697049
183	304-313	Species	denotes	2019-nCov	Tax:2697049
184	60-68	Disease	denotes	COVID-19	MESH:C000657245
185	78-86	Disease	denotes	COVID-19	MESH:C000657245
186	189-197	Disease	denotes	COVID-19	MESH:C000657245
187	885-893	Disease	denotes	COVID-19	MESH:C000657245

Id	Subject	Object	Predicate	Lexical cue
T114	37-41	CHEBI:23888;CHEBI:23888	denotes	drug
T115	60-68	SP_7	denotes	COVID-19
T116	78-86	SP_7	denotes	COVID-19
T117	189-197	SP_7	denotes	COVID-19
T118	304-313	SP_7	denotes	2019-nCov
T119	343-348	PR:000000125	denotes	nsp12
T120	366-371	PR:000000125	denotes	nsp12
T121	392-397	PR:000000125	denotes	nsp13
T122	408-416	SO:0000346	denotes	ADP site
T123	419-424	PR:000000125	denotes	nsp13
T124	446-451	PR:000000125	denotes	nsp14
T125	460-465	PR:000000125	denotes	nsp14
T126	478-483	PR:000000125	denotes	nsp15
T127	504-509	PR:000000125	denotes	nsp16
T128	524-533	PG_4	denotes	N protein
T129	547-556	PG_2	denotes	E protein
T130	558-561	CHEBI:24870;CHEBI:24870	denotes	ion
T131	688-692	SO:0000346	denotes	site
T132	867-876	CHEBI:36357;CHEBI:36357	denotes	compounds
T133	885-893	SP_7	denotes	COVID-19

Id	Subject	Object	Predicate	Lexical cue	fma_id
T19	292-300	Body_part	denotes	proteins	http://purl.org/sig/ont/fma/fma67257
T20	360-363	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T21	386-389	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T22	453-457	Body_part	denotes	ExoN	http://purl.org/sig/ont/fma/fma84120
T23	526-533	Body_part	denotes	protein	http://purl.org/sig/ont/fma/fma67257
T24	549-556	Body_part	denotes	protein	http://purl.org/sig/ont/fma/fma67257
T25	595-602	Body_part	denotes	Protein	http://purl.org/sig/ont/fma/fma67257
T26	652-655	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T27	672-675	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095
T28	718-722	Body_part	denotes	ExoN	http://purl.org/sig/ont/fma/fma84120
T29	901-909	Body_part	denotes	proteins	http://purl.org/sig/ont/fma/fma67257

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T34	60-68	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T35	78-86	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T36	189-197	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T37	885-893	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096

Id	Subject	Object	Predicate	Lexical cue	chebi_id
T48	37-41	Chemical	denotes	drug	http://purl.obolibrary.org/obo/CHEBI_23888
T49	292-300	Chemical	denotes	proteins	http://purl.obolibrary.org/obo/CHEBI_36080
T50	408-411	Chemical	denotes	ADP	http://purl.obolibrary.org/obo/CHEBI_16761\|http://purl.obolibrary.org/obo/CHEBI_456216\|http://purl.obolibrary.org/obo/CHEBI_73342
T53	526-533	Chemical	denotes	protein	http://purl.obolibrary.org/obo/CHEBI_36080
T54	549-556	Chemical	denotes	protein	http://purl.obolibrary.org/obo/CHEBI_36080
T55	558-561	Chemical	denotes	ion	http://purl.obolibrary.org/obo/CHEBI_24870
T56	595-602	Chemical	denotes	Protein	http://purl.obolibrary.org/obo/CHEBI_16541
T57	684-687	Chemical	denotes	ADP	http://purl.obolibrary.org/obo/CHEBI_16761\|http://purl.obolibrary.org/obo/CHEBI_456216\|http://purl.obolibrary.org/obo/CHEBI_73342
T60	901-909	Chemical	denotes	proteins	http://purl.obolibrary.org/obo/CHEBI_36080

Id	Subject	Object	Predicate	Lexical cue
T29	558-569	http://purl.obolibrary.org/obo/GO_0022831	denotes	ion channel

Id	Subject	Object	Predicate	Lexical cue
T66	0-22	Sentence	denotes	2.6 Molecular docking
T67	23-239	Sentence	denotes	To facilitate drug discovery against COVID-19, we used COVID-19 Docking Server (https://ncov.schanglab.org.cn/index.php) [23] to predict the binding modes between 12 COVID-19 targets and the 20 lead-likeness of QFPD.
T68	240-784	Sentence	denotes	Specifically, the 10 nonstructural and 2 structural proteins of 2019-nCov were collected (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site and E protein [ion channel]); and the corresponding Protein Data Bank (PDB)codes were 6LU7, 4OW0, 3H5Y (with RNA), 3H5Y (without RNA), 6JYT (ADP site), 6JYT (NCB site), 5C8S (ExoN),5C8S (N7-MTase), 2RHB, 2XYR, 4KYJ, and 5 × 29, respectively.
T69	785-910	Sentence	denotes	Finally, Discovery Studio software elucidated the 14 best docking results between compounds and the COVID-19 target proteins.