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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 19-34 Disease denotes COVID-19 injury MESH:C000657245
3 221-229 Disease denotes COVID-19 MESH:C000657245
5 356-365 Species denotes 2019-nCov Tax:2697049
7 428-436 Disease denotes COVID-19 MESH:C000657245
28 978-982 Gene denotes PPAR Gene:5465
29 1148-1154 Gene denotes MIR183 Gene:406959
30 1165-1169 Gene denotes CDK7 Gene:1022
31 1256-1260 Gene denotes ACE2 Gene:59272
32 1660-1669 Gene denotes X2 and O2
33 863-877 Gene denotes oxidoreductase Gene:8630
34 1777-1786 Species denotes 2019-nCov Tax:2697049
35 811-814 Chemical denotes FUs
36 888-893 Chemical denotes lipid MESH:D008055
37 956-963 Chemical denotes steroid MESH:D013256
38 1416-1421 Chemical denotes ADMET
39 544-552 Disease denotes COVID-19 MESH:C000657245
40 1042-1054 Disease denotes TTD diseases MESH:D003141
41 1064-1085 Disease denotes inflammatory diseases MESH:D007249
42 1087-1093 Disease denotes asthma MESH:D001249
43 1095-1132 Disease denotes chronic obstructive pulmonary Disease MESH:D029424
44 1242-1251 Disease denotes pneumonia MESH:D011014
45 1855-1863 Disease denotes COVID-19 MESH:C000657245
46 1920-1928 Disease denotes COVID-19 MESH:C000657245
47 2182-2190 Disease denotes COVID-19 MESH:C000657245
55 2402-2424 Species denotes 2019-novel coronavirus Tax:2697049
56 2426-2435 Species denotes 2019-nCov Tax:2697049
57 2554-2562 Species denotes patients Tax:9606
58 2737-2743 Species denotes people Tax:9606
59 2781-2787 Species denotes people Tax:9606
60 2588-2613 Disease denotes corona virus disease 2019 MESH:C000657245
61 2615-2623 Disease denotes COVID-19 MESH:C000657245
83 3855-3863 Species denotes Ma Huang Tax:3387
84 3909-3913 Species denotes Ling Tax:163112
85 2988-3014 Disease denotes viral infectious pneumonia
86 3066-3070 Disease denotes SARS MESH:D045169
87 3349-3424 Disease denotes Rhizoma Alismatis, Polyporus Umbellatus, Rhizoma Atractylodis Macrocephalae
88 3709-3717 Disease denotes COVID-19 MESH:C000657245
89 3896-3899 Disease denotes XCH
90 3989-4004 Disease denotes Febrile Disease MESH:D000071072
91 4151-4155 Disease denotes cold MESH:D000067390
92 4157-4162 Disease denotes fever MESH:D005334
93 4178-4194 Disease denotes virus infections MESH:D001102
94 4478-4484 Disease denotes asthma MESH:D001249
95 4486-4498 Disease denotes inflammation MESH:D007249
96 4500-4511 Disease denotes tonsillitis MESH:D014069
97 4516-4527 Disease denotes sore throat MESH:D010608
98 4533-4536 Disease denotes XCH
99 4743-4782 Disease denotes Rhizoma Alismatis, Polyporus Umbellatus
100 4862-4880 Disease denotes nephritic syndrome MESH:D061325
101 5002-5005 Disease denotes XCH
102 5396-5404 Disease denotes COVID-19 MESH:C000657245
103 5428-5431 Disease denotes XCH
107 5574-5582 Disease denotes COVID-19 MESH:C000657245
108 6325-6333 Disease denotes COVID-19 MESH:C000657245
109 6409-6417 Disease denotes COVID-19 MESH:C000657245
113 6472-6475 Disease denotes XCH
114 6534-6560 Disease denotes viral infectious pneumonia
115 6747-6755 Disease denotes COVID-19 MESH:C000657245
120 7079-7082 Disease denotes XCH
121 7206-7208 Disease denotes OB MESH:D009765
122 7254-7258 Disease denotes CIDs
123 7512-7516 Disease denotes CIDs
126 7920-7923 Disease denotes XCH
127 8096-8112 Disease denotes OMIM/TTD disease MESH:D003141
132 9046-9085 Gene denotes Kyoto Encyclopedia of Genes and Genomes
133 8856-8868 Species denotes Homo sapiens Tax:9606
134 8675-8678 Disease denotes XCH
135 9199-9202 Disease denotes XCH
139 9424-9427 Disease denotes XCH
140 9651-9654 Disease denotes XCH
141 9745-9748 Disease denotes XCH
153 10402-10406 Gene denotes OCT2 Gene:6582
154 10471-10475 Gene denotes hERG Gene:2078
155 10489-10493 Gene denotes hERG Gene:2078
156 10513-10516 Species denotes rat Tax:10116
157 10422-10430 Disease denotes toxicity MESH:D064420
158 10437-10445 Disease denotes toxicity MESH:D064420
159 10523-10531 Disease denotes toxicity MESH:D064420
160 10540-10554 Disease denotes hepatotoxicity MESH:D056486
161 10556-10574 Disease denotes skin sensitisation MESH:D012871
162 10587-10595 Disease denotes toxicity MESH:D064420
163 10211-10217 CellLine denotes Caco-2 CVCL:0025
176 10929-10933 Gene denotes Mpro Gene:8673700
177 10949-10953 Gene denotes RdRp Gene:43740578
178 10972-10976 Gene denotes RdRp Gene:43740578
179 10998-11006 Gene denotes Helicase Gene:164045
180 11025-11033 Gene denotes Helicase Gene:164045
181 10935-10940 Gene denotes PLpro Gene:43740578
182 10710-10714 Species denotes ncov Tax:2697049
183 10903-10912 Species denotes 2019-nCov Tax:2697049
184 10659-10667 Disease denotes COVID-19 MESH:C000657245
185 10677-10685 Disease denotes COVID-19 MESH:C000657245
186 10788-10796 Disease denotes COVID-19 MESH:C000657245
187 11484-11492 Disease denotes COVID-19 MESH:C000657245
190 11516-11520 Gene denotes ACE2 Gene:59272
191 11525-11530 Gene denotes CD147 Gene:682
198 11630-11634 Gene denotes ACE2 Gene:59272
199 11639-11644 Gene denotes CD147 Gene:682
200 11772-11776 Gene denotes ACE2 Gene:59272
201 11781-11786 Gene denotes CD147 Gene:682
202 12004-12008 Gene denotes ACE2 Gene:59272
203 11896-11905 Disease denotes pneumonia MESH:D011014
206 12293-12301 Disease denotes COVID-19 MESH:C000657245
207 12310-12331 Disease denotes robustness of disease MESH:D003141
216 12362-12370 Disease denotes COVID-19 MESH:C000657245
217 12909-12917 Disease denotes COVID-19 MESH:C000657245
218 12981-12989 Disease denotes COVID-19 MESH:C000657245
219 13033-13037 Disease denotes SARS MESH:D045169
220 13172-13180 Disease denotes COVID-19 MESH:C000657245
221 13348-13351 Disease denotes XCH
222 13524-13532 Disease denotes COVID-19 MESH:C000657245
223 13728-13748 Disease denotes Banxia tianma baizhu
227 15774-15865 Disease denotes CID1174,CID3026,CID5789,CID6782,CID6998,CID8437,CID8679,CID13625,CID117158,CID159225,CID185
228 16162-16248 Disease denotes CID5488781,CID5491637,CID64959,CID64982,CID676152,CID71307581,CID72307,CID13688752 XCH
229 17319-17389 Disease denotes CID64959,CID64971,CID64982,CID73205,CID821279,CID928837,CID9927807 WLS
235 13974-13976 Disease denotes OB MESH:D009765
236 14245-14248 Disease denotes XCH
237 14460-14463 Disease denotes XCH
238 14512-14515 Disease denotes XCH
239 14680-14683 Disease denotes XCH
260 18237-18251 Gene denotes oxidoreductase Gene:8630
261 18690-18694 Gene denotes PPAR Gene:5465
262 18262-18267 Chemical denotes lipid MESH:D008055
263 18287-18292 Chemical denotes lipid MESH:D008055
264 18564-18571 Chemical denotes dteroid
265 18660-18667 Chemical denotes steroid MESH:D013256
266 18714-18722 Chemical denotes arginine MESH:D001120
267 18727-18734 Chemical denotes proline MESH:D011392
268 19165-19177 Chemical denotes beta-Alanine MESH:D015091
269 18904-18908 Disease denotes acne MESH:D000152
270 18916-18926 Disease denotes 'S disease MESH:D000755
271 18928-18955 Disease denotes benign prostate hyperplasia MESH:D011470
272 18957-18981 Disease denotes intrahepatic cholestasis MESH:D002780
273 18986-18998 Disease denotes brain injury MESH:D001930
274 19075-19078 Disease denotes XCH
275 19245-19265 Disease denotes parasitic infections MESH:D010272
276 19314-19326 Disease denotes hypertension MESH:D006973
277 19337-19340 Disease denotes XCH
278 19394-19417 Disease denotes ovarian steroidogenesis MESH:D010049
279 19430-19451 Disease denotes inflammatory diseases MESH:D007249
284 19720-19727 Gene denotes MIR-183 Gene:406959
285 19732-19740 Gene denotes MIR-130A Gene:406919
286 19921-19925 Gene denotes CDK7 Gene:1022
287 19978-19981 Disease denotes XCH
289 21811-21814 Disease denotes XCH
295 21232-21238 Gene denotes COX7A1 Gene:1346
296 21308-21315 Gene denotes ALDH1A1 Gene:216
297 21383-21387 Gene denotes CNR2 Gene:1269
298 21505-21512 Chemical denotes calcium MESH:D002118
299 21568-21571 Chemical denotes TRP MESH:D014364
302 22069-22075 Gene denotes COX7A1 Gene:1346
303 22154-22174 Disease denotes huntington's disease MESH:D006816
305 22488-22492 Gene denotes CNR2 Gene:1269
310 22934-22939 Gene denotes ACSS1 Gene:84532
311 23006-23010 Gene denotes CNR2 Gene:1269
312 23077-23082 Gene denotes PRKCG Gene:5582
313 23159-23166 Gene denotes insulin Gene:3630
323 23494-23500 Gene denotes COX7A1 Gene:1346
324 23570-23574 Gene denotes RRM1 Gene:6240
325 23642-23646 Gene denotes CNR2 Gene:1269
326 23716-23721 Gene denotes ACSS1 Gene:84532
327 23788-23793 Gene denotes FFAR1 Gene:2864
328 23869-23876 Chemical denotes calcium MESH:D002118
329 23896-23900 Chemical denotes cGMP MESH:D006152
330 23289-23292 Disease denotes XCH
331 23840-23843 Disease denotes XCH
335 24968-24972 Gene denotes KEGG
336 25093-25097 Disease denotes OMIN
337 25142-25145 Disease denotes XCH
342 24114-24117 Disease denotes XCH
343 24307-24310 Disease denotes XCH
344 24561-24564 Disease denotes XCH
345 24752-24760 Disease denotes COVID-19 MESH:C000657245
361 26659-26663 Gene denotes OCT2 Gene:6582
362 26465-26470 Species denotes Human Tax:9606
363 26550-26555 Species denotes Human Tax:9606
364 26752-26757 Species denotes Human Tax:9606
365 26808-26811 Species denotes Rat Tax:10116
366 26410-26415 Chemical denotes Caco2
367 26638-26640 Chemical denotes TC MESH:D013667
368 26722-26726 Chemical denotes MTDD
369 26296-26304 Disease denotes toxicity MESH:D064420
370 26712-26720 Disease denotes toxicity MESH:D064420
371 26818-26826 Disease denotes Toxicity MESH:D064420
372 26839-26853 Disease denotes Hepatotoxicity MESH:D056486
373 26859-26877 Disease denotes Skin Sensitisation MESH:D012871
374 26890-26898 Disease denotes toxicity MESH:D064420
375 26417-26423 CellLine denotes Caco-2 CVCL:0025
383 27211-27219 Gene denotes Helicase Gene:164045
384 27278-27283 Gene denotes PLpro Gene:43740578
385 27295-27299 Gene denotes Mpro Gene:8673700
386 27311-27315 Gene denotes Mpro Gene:8673700
387 27248-27256 Gene denotes Helicase Gene:164045
388 27140-27148 Disease denotes COVID-19 MESH:C000657245
389 27338-27341 Disease denotes XCH
391 28979-28982 Disease denotes XCH
403 28017-28021 Gene denotes OCT2 Gene:6582
404 28144-28148 Gene denotes hERG Gene:2078
405 28162-28166 Gene denotes hERG Gene:2078
406 28186-28189 Species denotes rat Tax:10116
407 28077-28085 Disease denotes toxicity MESH:D064420
408 28110-28118 Disease denotes toxicity MESH:D064420
409 28196-28204 Disease denotes toxicity MESH:D064420
410 28213-28227 Disease denotes hepatotoxicity MESH:D056486
411 28229-28247 Disease denotes skin sensitisation MESH:D012871
412 28260-28268 Disease denotes toxicity MESH:D064420
413 27481-27487 CellLine denotes Caco-2 CVCL:0025
418 30090-30094 Gene denotes RdRp Gene:43740578
419 30159-30163 Gene denotes RdRp Gene:43740578
420 30231-30239 Gene denotes Helicase Gene:164045
421 30300-30308 Gene denotes Helicase Gene:164045
423 29886-29895 Species denotes 2019-nCov Tax:2697049
425 30828-30831 Disease denotes XCH
429 31160-31166 Gene denotes ClC −6 Gene:1185
430 30950-30962 Disease denotes SGMH XCH WLS
431 31071-31074 Disease denotes APL MESH:D015473
433 30918-30926 Disease denotes COVID-19 MESH:C000657245
436 31594-31598 Chemical denotes BXTM
437 31456-31459 Disease denotes APL MESH:D015473
446 29227-29242 Gene denotes SX1, O1, X2, X1
447 29305-29309 Gene denotes Mpro Gene:8673700
448 29325-29329 Gene denotes RdRp Gene:43740578
449 29348-29352 Gene denotes RdRp Gene:43740578
450 29374-29382 Gene denotes Helicase Gene:164045
451 29401-29409 Gene denotes Helicase Gene:164045
452 29311-29316 Gene denotes PLpro Gene:43740578
453 29038-29046 Disease denotes COVID-19 MESH:C000657245
480 31910-31918 Gene denotes Helicase Gene:164045
481 32579-32583 Gene denotes Mpro Gene:8673700
482 32807-32811 Gene denotes Mpro Gene:8673700
483 32362-32367 Gene denotes PLpro Gene:43740578
484 32138-32146 Gene denotes Helicase Gene:164045
485 31805-31808 Chemical denotes TYR MESH:D014443
486 31813-31816 Chemical denotes ALA MESH:D000409
487 31821-31824 Chemical denotes ILE MESH:D007532
488 31832-31835 Chemical denotes PRO MESH:D011392
489 32010-32013 Chemical denotes ASN MESH:D001216
490 32019-32022 Chemical denotes ARG MESH:D001120
491 32028-32031 Chemical denotes LEU MESH:D007930
492 32039-32042 Chemical denotes PRO MESH:D011392
493 32624-32632 Chemical denotes hydrogen MESH:D006859
494 32687-32690 Chemical denotes GLU MESH:D018698
495 32696-32699 Chemical denotes LEU MESH:D007930
496 32708-32711 Chemical denotes CYS MESH:D003545
497 32722-32724 Chemical denotes O2 MESH:D010100
498 32843-32849 Chemical denotes Carbon MESH:D002244
499 32850-32858 Chemical denotes hydrogen MESH:D006859
500 32868-32873 Chemical denotes anion MESH:D000838
501 32878-32884 Chemical denotes sulfur MESH:D013455
502 32934-32937 Chemical denotes GLY
503 32942-32945 Chemical denotes LEU MESH:D007930
504 32954-32957 Chemical denotes CYS MESH:D003545
505 32543-32546 Disease denotes XCH
512 35141-35145 Gene denotes RdRp Gene:43740578
513 35178-35182 Gene denotes RdRp Gene:43740578
514 34913-34921 Disease denotes COVID-19 MESH:C000657245
515 35226-35229 Disease denotes XCH
516 35244-35247 Disease denotes XCH
517 35273-35276 Disease denotes XCH
537 34353-34357 Gene denotes RdRp Gene:43740578
538 34633-34637 Gene denotes RdRp Gene:43740578
539 33608-33611 Chemical denotes PRO MESH:D011392
540 33617-33620 Chemical denotes VAL MESH:D014633
541 33626-33629 Chemical denotes LYS MESH:D008239
542 33638-33641 Chemical denotes SER MESH:D012694
543 33814-33817 Chemical denotes PHE MESH:D010649
544 33983-33986 Chemical denotes LYS MESH:D008239
545 33992-33995 Chemical denotes LYS MESH:D008239
546 34001-34004 Chemical denotes VAL MESH:D014633
547 34013-34016 Chemical denotes PRO MESH:D011392
548 34688-34696 Chemical denotes hydrogen MESH:D006859
549 34758-34761 Chemical denotes CYS MESH:D003545
550 34767-34770 Chemical denotes GLY
551 34776-34779 Chemical denotes LYS MESH:D008239
552 34788-34791 Chemical denotes ASP MESH:D001224
553 33470-33473 Disease denotes XCH
554 33699-33702 Disease denotes XCH
555 34581-34584 Disease denotes XCH
558 35295-35299 Gene denotes ACE2 Gene:59272
559 35304-35309 Gene denotes CD147 Gene:682
570 36391-36395 Gene denotes ACE2 Gene:59272
571 36400-36405 Gene denotes CD147 Gene:682
572 36474-36478 Gene denotes ACE2 Gene:59272
573 36483-36488 Gene denotes CD147 Gene:682
574 36706-36710 Gene denotes ACE2 Gene:59272
575 36748-36753 Gene denotes CD147 Gene:682
576 36796-36800 Gene denotes ACE2 Gene:59272
577 36695-36704 Disease denotes pneumonia MESH:D011014
578 36824-36831 Disease denotes colonic MESH:D003110
579 36855-36862 Disease denotes colonic MESH:D003110
600 35419-35423 Gene denotes ACE2 Gene:59272
601 35428-35433 Gene denotes CD147 Gene:682
602 35498-35502 Gene denotes ACE2 Gene:59272
603 35507-35512 Gene denotes CD147 Gene:682
604 35586-35590 Gene denotes ACE2 Gene:59272
605 35752-35757 Gene denotes CD147 Gene:682
606 35977-35981 Gene denotes ACE2 Gene:59272
607 36010-36015 Gene denotes CD147 Gene:682
608 36118-36122 Gene denotes ACE2 Gene:59272
609 36349-36353 Gene denotes ACE2 Gene:59272
610 36358-36363 Gene denotes CD147 Gene:682
611 35366-35375 Species denotes 2019-nCov Tax:2697049
612 35927-35936 Species denotes 2019-nCov Tax:2697049
613 36327-36336 Species denotes 2019-nCov Tax:2697049
614 35814-35830 Disease denotes atrial appendage MESH:D018280
615 35914-35923 Disease denotes pneumonia MESH:D011014
616 36021-36030 Disease denotes pneumonia MESH:D011014
617 36126-36133 Disease denotes colonic MESH:D003110
618 36303-36311 Disease denotes COVID-19 MESH:C000657245
619 36338-36347 Disease denotes pneumonia MESH:D011014
622 37328-37336 Disease denotes COVID-19 MESH:C000657245
623 37345-37366 Disease denotes robustness of disease MESH:D003141
626 37975-37983 Disease denotes COVID-19 MESH:C000657245
627 38225-38228 Disease denotes XCH
633 38653-38687 Gene denotes MXO1 SO1 SX1 WO1 XO1 Main Protease
634 38795-38799 Gene denotes RdRp Gene:43740578
635 38850-38854 Gene denotes RdRp Gene:43740578
636 38910-38918 Gene denotes Helicase Gene:164045
637 38973-38981 Gene denotes Helicase Gene:164045
639 38606-38615 Species denotes 2019-nCov Tax:2697049
641 39433-39436 Disease denotes XCH
645 37484-37492 Disease denotes COVID-19 MESH:C000657245
646 37569-37572 Disease denotes XCH
647 37603-37611 Disease denotes COVID-19 MESH:C000657245
649 39979-39987 Disease denotes COVID-19 MESH:C000657245
665 39680-39685 Gene denotes Cdc20 Gene:991
666 39687-39691 Gene denotes Ido1 Gene:3620
667 39693-39697 Gene denotes Ifng Gene:3458
668 39699-39703 Gene denotes Il10 Gene:3586
669 39705-39708 Gene denotes Il6 Gene:3569
670 39710-39716 Gene denotes Ptger4 Gene:5734
671 39718-39722 Gene denotes Spi1 Gene:6688
672 39724-39727 Gene denotes Tnf Gene:7124
673 39872-39881 Species denotes influenza Tax:11320
674 39499-39507 Disease denotes COVID-19 MESH:C000657245
675 39621-39624 Disease denotes XCH
676 39764-39772 Disease denotes COVID-19 MESH:C000657245
677 39797-39822 Disease denotes Graft-versus-host disease MESH:D006086
678 39864-39870 Disease denotes asthma MESH:D001249
679 39885-39911 Disease denotes inflammatory bowel disease MESH:D015212
696 40632-40640 Species denotes patients Tax:9606
697 41203-41211 Species denotes patients Tax:9606
698 41224-41241 Species denotes novel coronavirus Tax:2697049
699 40400-40433 Disease denotes coronavirus (2019-nCov) infection MESH:C000657245
700 40492-40501 Disease denotes infection MESH:D007239
701 40514-40549 Disease denotes acute respiratory distress syndrome MESH:D012128
702 40551-40555 Disease denotes ARDS MESH:D012128
703 40561-40571 Disease denotes septicemia MESH:D018805
704 40596-40601 Disease denotes death MESH:D003643
705 40651-40685 Disease denotes multi-organ damage and dysfunction MESH:D009102
706 40765-40773 Disease denotes COVID-19 MESH:C000657245
707 41013-41021 Disease denotes COVID-19 MESH:C000657245
708 41080-41085 Disease denotes fever MESH:D005334
709 41193-41202 Disease denotes pneumonia MESH:D011014
710 41212-41220 Disease denotes infected MESH:D007239
711 41319-41327 Disease denotes COVID-19 MESH:C000657245
734 41719-41733 Gene denotes oxidoreductase Gene:8630
735 42312-42316 Gene denotes PPAR Gene:5465
736 42499-42503 Gene denotes PPAR Gene:5465
737 43421-43426 Gene denotes Cdc20 Gene:991
738 43428-43432 Gene denotes Ido1 Gene:3620
739 43434-43438 Gene denotes Ifng Gene:3458
740 43440-43444 Gene denotes Il10 Gene:3586
741 43446-43449 Gene denotes Il6 Gene:3569
742 43451-43457 Gene denotes Ptger4 Gene:5734
743 43459-43463 Gene denotes Spi1 Gene:6688
744 43465-43468 Gene denotes Tnf Gene:7124
745 42528-42532 Species denotes H1N1 Tax:114727
746 41744-41749 Chemical denotes lipid MESH:D008055
747 41769-41774 Chemical denotes lipid MESH:D008055
748 41988-41993 Chemical denotes lipid MESH:D008055
749 42180-42185 Chemical denotes lipid MESH:D008055
750 42765-42772 Chemical denotes calcium MESH:D002118
751 41538-41543 Disease denotes COVID MESH:C000657245
752 41662-41665 Disease denotes XCH
753 42533-42542 Disease denotes infection MESH:D007239
754 43308-43311 Disease denotes XCH
755 43340-43348 Disease denotes COVID-19 MESH:C000657245
771 43804-43808 Gene denotes ACE2 Gene:59272
772 43883-43887 Gene denotes ACE2 Gene:59272
773 44088-44092 Gene denotes ACE2 Gene:59272
774 43629-43638 Species denotes 2019-nCov Tax:2697049
775 44063-44072 Species denotes 2019-nCov Tax:2697049
776 43665-43676 Disease denotes dysfunction MESH:D009461
777 44074-44083 Disease denotes pneumonia MESH:D011014
778 44172-44180 Disease denotes COVID-19 MESH:C000657245
779 44313-44321 Disease denotes COVID-19 MESH:C000657245
780 44355-44376 Disease denotes inflammatory diseases MESH:D007249
781 44378-44384 Disease denotes asthma MESH:D001249
782 44386-44412 Disease denotes inflammatory bowel disease MESH:D015212
783 44414-44451 Disease denotes chronic obstructive pulmonary disease MESH:D029424
784 44453-44477 Disease denotes intrahepatic cholestasis MESH:D002780
785 44487-44494 Disease denotes ileitis MESH:D007079
791 45143-45152 Gene denotes X2 and O2
792 45292-45301 Species denotes 2019-nCov Tax:2697049
793 44518-44536 Chemical denotes ADMETox prediction
794 44912-44920 Disease denotes toxicity MESH:D064420
795 45368-45376 Disease denotes COVID-19 MESH:C000657245
818 45772-45778 Gene denotes MIR183 Gene:406959
819 45783-45796 Gene denotes MIR130A/B/301 Gene:406919
820 45930-45934 Gene denotes CDKs Gene:1022
821 46174-46178 Gene denotes CDK7 Gene:1022
822 46297-46301 Gene denotes CDK7 Gene:1022
823 45681-45687 Gene denotes MIR183 Gene:406959
824 45707-45711 Species denotes H1N1 Tax:114727
825 45712-45720 Species denotes patients Tax:9606
826 46013-46018 Species denotes human Tax:9606
827 46044-46065 Species denotes human cytomegalovirus Tax:10359
828 46112-46117 Species denotes HSV-2 Tax:10310
829 46501-46505 Species denotes H1N1 Tax:114727
830 46067-46071 Species denotes HCMV Tax:10359
831 46420-46431 Chemical denotes cholesterol MESH:D002784
832 45573-45588 Disease denotes virus infection MESH:D001102
833 45885-45893 Disease denotes COVID-19 MESH:C000657245
834 46019-46042 Disease denotes HIV-1, papillomaviruses MESH:D015658
835 46276-46284 Disease denotes COVID-19 MESH:C000657245
836 46451-46463 Disease denotes inflammation MESH:D007249
837 46516-46531 Disease denotes virus infection MESH:D001102
838 46600-46603 Disease denotes XCH
839 46716-46731 Disease denotes virus infection MESH:D001102
849 46783-46791 Disease denotes COVID-19 MESH:C000657245
850 47002-47006 Disease denotes SARS MESH:D045169
851 47052-47060 Disease denotes COVID-19 MESH:C000657245
852 47082-47090 Disease denotes COVID-19 MESH:C000657245
853 47131-47139 Disease denotes COVID-19 MESH:C000657245
854 47357-47365 Disease denotes COVID-19 MESH:C000657245
855 47462-47470 Disease denotes COVID-19 MESH:C000657245
856 47729-47737 Disease denotes COVID-19 MESH:C000657245
857 47836-47844 Disease denotes COVID-19 MESH:C000657245
860 48087-48091 Species denotes Ling Tax:163112
861 48203-48207 Species denotes Ling Tax:163112

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1 19-27 SP_7 denotes COVID-19
T2 71-76 NCBITaxon:10239 denotes viral
T3 109-118 GO:0008152 denotes metabolic
T4 221-229 SP_7 denotes COVID-19
T5 239-244 NCBITaxon:10239 denotes viral
T6 250-263 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T7 268-277 GO:0008152 denotes metabolic
T8 356-365 SP_7 denotes 2019-nCov
T9 428-436 SP_7 denotes COVID-19
T16 544-552 SP_7 denotes COVID-19
T17 583-592 CHEBI:36357;CHEBI:36357 denotes compounds
T18 888-893 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T19 894-911 GO:0006629 denotes metabolic process
T20 913-932 GO:0042592 denotes homeostatic process
T21 956-963 CHEBI:35341;CHEBI:35341;GO:0006694 denotes steroid
T22 964-976 GO:0006694 denotes biosynthesis
T23 1115-1124 UBERON:0002048 denotes pulmonary
T24 1141-1146 SO:0000276 denotes miRNA
T25 1165-1169 PR:000005265 denotes CDK7
T26 1256-1260 G_3;PG_10;PR:000003622 denotes ACE2
T27 1264-1274 GO:0010467 denotes expression
T28 1449-1458 CHEBI:36357;CHEBI:36357 denotes compounds
T29 1513-1517 CHEBI:23888;CHEBI:23888 denotes drug
T30 1542-1558 UBERON:0001555 denotes gastrointestinal
T31 1667-1669 CHEBI:15379;CHEBI:15379 denotes O2
T32 1777-1786 SP_7 denotes 2019-nCov
T33 1834-1838 CHEBI:23888;CHEBI:23888 denotes drug
T34 1855-1863 SP_7 denotes COVID-19
T35 1920-1928 SP_7 denotes COVID-19
T36 1970-1979 GO:0010467 denotes expressed
T37 1980-1984 CHEBI:23888;CHEBI:23888 denotes drug
T38 2026-2035 NCBITaxon:2 denotes bacterial
T39 2040-2045 NCBITaxon:10239 denotes viral
T40 2057-2070 UBERON:0002405 denotes immune system
T41 2182-2190 SP_7 denotes COVID-19
T42 2194-2204 GO:0065007 denotes regulating
T43 2305-2315 GO:0065007 denotes regulation
T44 2324-2329 NCBITaxon:10239 denotes viral
T45 2362-2371 GO:0008152 denotes metabolic
T46 2413-2424 NCBITaxon:11118 denotes coronavirus
T47 2426-2435 SP_7 denotes 2019-nCov
T48 2588-2600 NCBITaxon:11118 denotes corona virus
T49 2615-2623 SP_7 denotes COVID-19
T50 2634-2639 NCBITaxon:10239 denotes virus
T51 2737-2743 NCBITaxon:9606 denotes people
T52 2781-2787 NCBITaxon:9606 denotes people
T53 2899-2904 CHEBI:23888;CHEBI:23888 denotes drugs
T54 2931-2936 NCBITaxon:10239 denotes virus
T55 2988-2993 NCBITaxon:10239 denotes viral
T56 3066-3070 SP_10 denotes SARS
T57 3378-3388 NCBITaxon:158314 denotes Umbellatus
T58 3411-3424 NCBITaxon:9539 denotes Macrocephalae
T59 3426-3431 NCBITaxon:6040 denotes Poria
T60 3709-3717 SP_7 denotes COVID-19
T61 4178-4183 NCBITaxon:10239 denotes virus
T62 4212-4217 NCBITaxon:10239 denotes viral
T63 4218-4225 GO:0009986 denotes surface
T64 4251-4256 NCBITaxon:10239;GO:0035376 denotes viral
T65 4257-4262 GO:0035376 denotes entry
T66 4521-4527 UBERON:0000341 denotes throat
T67 4580-4592 NCBITaxon:4932 denotes Scutellariae
T68 4686-4702 CHEBI:67079;CHEBI:67079 denotes anticarcinogenic
T69 4762-4782 NCBITaxon:158314 denotes Polyporus Umbellatus
T70 4894-4900 UBERON:0002113 denotes kidney
T71 4901-4910 GO:0007588 denotes excretion
T72 5396-5404 SP_7 denotes COVID-19
T73 5574-5582 SP_7 denotes COVID-19
T74 5598-5613 CHEBI:52217;CHEBI:52217 denotes pharmacological
T75 5692-5704 CHEBI:52217;CHEBI:52217 denotes pharmacology
T76 5766-5771 CHEBI:23888;CHEBI:23888 denotes drugs
T77 5909-5921 CHEBI:52217;CHEBI:52217 denotes pharmacology
T78 6325-6333 SP_7 denotes COVID-19
T79 6409-6417 SP_7 denotes COVID-19
T80 6534-6539 NCBITaxon:10239 denotes viral
T81 6610-6619 CHEBI:36357;CHEBI:36357 denotes compounds
T82 6747-6755 SP_7 denotes COVID-19
T83 6795-6807 CHEBI:52217;CHEBI:52217 denotes pharmacology
T84 7150-7154 CHEBI:23888;CHEBI:23888 denotes drug
T85 7266-7275 CHEBI:36357;CHEBI:36357 denotes compounds
T86 7460-7465 SO:0001867 denotes genes
T87 8034-8038 SO:0000704 denotes Gene
T88 8148-8156 SO:0000646 denotes microRNA
T89 8555-8562 SO:0000417 denotes modules
T90 8595-8610 CHEBI:52217;CHEBI:52217 denotes pharmacological
T91 8836-8843 NCBITaxon:species denotes species
T92 8856-8868 SP_6;NCBITaxon:9606 denotes Homo sapiens
T93 8937-8944 SO:0000417 denotes modules
T94 9068-9073 SO:0000704 denotes Genes
T95 9078-9085 SO:0001026 denotes Genomes
T96 9176-9183 SO:0000417 denotes modules
T97 9625-9634 CHEBI:36357;CHEBI:36357 denotes compounds
T98 9720-9729 CHEBI:36357;CHEBI:36357 denotes compounds
T99 9857-9866 CHEBI:36357;CHEBI:36357 denotes compounds
T100 10109-10124 CHEBI:52217;CHEBI:52217 denotes pharmacokinetic
T101 10211-10217 CL_1 denotes Caco-2
T102 10303-10322 UBERON:0000120 denotes blood-brain barrier
T103 10327-10349 UBERON:0001017 denotes central nervous system
T104 10365-10374 GO:0007588 denotes excretion
T105 10396-10401 UBERON:0002113 denotes renal
T106 10402-10406 PR:000013036 denotes OCT2
T107 10432-10436 CHEBI:34018;CHEBI:34018 denotes AMES
T108 10471-10475 PR:P11308 denotes hERG
T109 10478-10487 CHEBI:35222;CHEBI:35222 denotes inhibitor
T110 10489-10493 PR:P11308 denotes hERG
T111 10497-10506 CHEBI:35222;CHEBI:35222 denotes inhibitor
T112 10508-10512 UBERON:0000165 denotes oral
T113 10513-10516 NCBITaxon:10114 denotes rat
T114 10636-10640 CHEBI:23888;CHEBI:23888 denotes drug
T115 10659-10667 SP_7 denotes COVID-19
T116 10677-10685 SP_7 denotes COVID-19
T117 10788-10796 SP_7 denotes COVID-19
T118 10903-10912 SP_7 denotes 2019-nCov
T119 10942-10947 PR:000000125 denotes nsp12
T120 10965-10970 PR:000000125 denotes nsp12
T121 10991-10996 PR:000000125 denotes nsp13
T122 11007-11015 SO:0000346 denotes ADP site
T123 11018-11023 PR:000000125 denotes nsp13
T124 11045-11050 PR:000000125 denotes nsp14
T125 11059-11064 PR:000000125 denotes nsp14
T126 11077-11082 PR:000000125 denotes nsp15
T127 11103-11108 PR:000000125 denotes nsp16
T128 11123-11132 PG_4 denotes N protein
T129 11146-11155 PG_2 denotes E protein
T130 11157-11160 CHEBI:24870;CHEBI:24870 denotes ion
T131 11287-11291 SO:0000346 denotes site
T132 11466-11475 CHEBI:36357;CHEBI:36357 denotes compounds
T133 11484-11492 SP_7 denotes COVID-19
T134 11516-11520 G_3;PG_10;PR:000003622 denotes ACE2
T135 11525-11530 PR:000001324 denotes CD147
T136 11531-11541 GO:0010467 denotes expression
T137 11549-11556 UBERON:0000479 denotes tissues
T138 11564-11574 GO:0010467 denotes expression
T139 11575-11580 SO:0000704 denotes genes
T140 11599-11609 GO:0010467 denotes expression
T141 11630-11634 G_3;PG_10;PR:000003622 denotes ACE2
T142 11639-11644 PR:000001324 denotes CD147
T143 11652-11659 UBERON:0000479 denotes tissues
T144 11687-11694 UBERON:0000479 denotes tissues
T145 11752-11762 GO:0010467 denotes expression
T146 11763-11768 SO:0000704 denotes genes
T147 11772-11776 G_3;PG_10;PR:000003622 denotes ACE2
T148 11781-11786 PR:000001324 denotes CD147
T149 11917-11922 SO:0000704 denotes genes
T150 11984-11994 GO:0010467 denotes expression
T151 11995-12000 SO:0000704 denotes genes
T152 12004-12008 G_3;PG_10;PR:000003622 denotes ACE2
T153 12012-12019 UBERON:0001155;CL:0011108 denotes colonic
T154 12020-12030 CL:0011108;UBERON:0000483 denotes epithelial
T155 12031-12036 CL:0011108 denotes cells
T156 12062-12066 GO:0018995 denotes host
T157 12259-12263 CHEBI:23888;CHEBI:23888 denotes drug
T158 12293-12301 SP_7 denotes COVID-19
T159 12362-12370 SP_7 denotes COVID-19
T160 12544-12549 CHEBI:23888;CHEBI:23888 denotes drugs
T161 12621-12626 CHEBI:23888;CHEBI:23888 denotes drugs
T162 12711-12716 CHEBI:23888;CHEBI:23888 denotes drugs
T163 12809-12813 CHEBI:23888;CHEBI:23888 denotes drug
T164 12881-12886 CHEBI:23888;CHEBI:23888 denotes drugs
T165 12909-12917 SP_7 denotes COVID-19
T166 12981-12989 SP_7 denotes COVID-19
T167 13014-13023 GO:0010467 denotes expressed
T168 13024-13029 SO:0000704 denotes genes
T169 13033-13037 SP_10 denotes SARS
T170 13172-13180 SP_7 denotes COVID-19
T171 13445-13449 CHEBI:23888;CHEBI:23888 denotes drug
T172 13524-13532 SP_7 denotes COVID-19
T173 13673-13678 CHEBI:23888;CHEBI:23888 denotes drugs
T174 18021-18030 CHEBI:36357;CHEBI:36357 denotes compounds
T175 18047-18056 CHEBI:36357;CHEBI:36357 denotes compounds
T178 18262-18267 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T179 18268-18285 GO:0006629 denotes metabolic process
T180 18287-18292 CHEBI:18059;CHEBI:18059 denotes lipid
T181 18308-18316 CHEBI:36357;CHEBI:36357 denotes molecule
T182 18317-18334 GO:0044281 denotes metabolic process
T183 18336-18355 GO:0042592 denotes homeostatic process
T184 18388-18406 GO:0008283 denotes cell proliferation
T185 18564-18571 CHEBI:26537;CHEBI:26537 denotes dteroid
T186 18572-18584 GO:0006695 denotes biosynthesis
T187 18660-18667 GO:0006695;CHEBI:26764;CHEBI:26764 denotes steroid
T188 18668-18675 CHEBI:26764;CHEBI:26764;GO:0042446 denotes hormone
T189 18676-18688 GO:0042446 denotes biosynthesis
T190 18714-18722 GO:0006520 denotes arginine
T191 18727-18745 GO:0006560 denotes proline metabolism
T192 18935-18943 UBERON:0002367 denotes prostate
T193 18957-18969 UBERON:0002107 denotes intrahepatic
T194 18986-18991 UBERON:0000955 denotes brain
T195 19133-19152 UBERON:0001016 denotes neurological system
T196 19165-19177 GO:0006635 denotes beta-Alanine
T197 19178-19188 GO:0019482 denotes metabolism
T198 19219-19227 GO:0016020 denotes membrane
T199 19273-19276 UBERON:0000970 denotes eye
T200 19303-19309 GO:0007623 denotes rhythm
T201 19342-19349 GO:0005634 denotes nucleic
T202 19394-19401 UBERON:0000992 denotes ovarian
T203 19402-19417 GO:0006694 denotes steroidogenesis
T204 19696-19702 SO:0000276 denotes miRNAs
T205 19862-19868 SO:0000276 denotes miRNAs
T206 19921-19925 PR:000005265 denotes CDK7
T207 20180-20185 SO:0000276 denotes miRNA
T208 20337-20342 SO:0000646 denotes miRNA
T209 20382-20387 SO:0000276 denotes miRNA
T210 20486-20491 SO:0000276 denotes miRNA
T211 20532-20537 SO:0000276 denotes miRNA
T217 20601-20608 SO:0000417 denotes modules
T218 20739-20745 GO:0007601 denotes visual
T219 20818-20823 SO:0001867 denotes genes
T220 21020-21026 SO:0000417 denotes module
T221 21105-21112 SO:0000417 denotes modules
T222 21223-21227 SO:0000704 denotes gene
T223 21232-21238 PR:000005786 denotes COX7A1
T224 21299-21303 SO:0000704 denotes gene
T225 21308-21315 PR:000003920 denotes ALDH1A1
T226 21374-21378 SO:0000704 denotes gene
T227 21383-21387 PR:000001126 denotes CNR2
T228 21439-21446 SO:0000417 denotes modules
T229 21505-21530 GO:0019722 denotes calcium signaling pathway
T230 21532-21553 CHEBI:67079;CHEBI:67079 denotes inflammatory mediator
T231 21554-21564 GO:0065007 denotes regulation
T232 21568-21571 PR:000016138 denotes TRP
T233 21619-21626 SO:0000417 denotes modules
T234 21762-21769 SO:0000417 denotes modules
T237 21850-21855 SO:0001867 denotes genes
T238 22060-22064 SO:0000704 denotes gene
T239 22069-22075 PR:000005786 denotes COX7A1
T240 22129-22136 SO:0000417 denotes modules
T241 22176-22186 GO:0006096 denotes glycolysis
T242 22189-22204 GO:0006094 denotes gluconeogenesis
T243 22206-22229 GO:0007219 denotes Notch signaling pathway
T244 22271-22276 SO:0001867 denotes genes
T245 22479-22483 SO:0000704 denotes gene
T246 22488-22492 PR:000001126 denotes CNR2
T247 22543-22550 SO:0000417 denotes modules
T248 22568-22575 UBERON:0002046;GO:0048538;CHEBI:60311;CHEBI:60311 denotes thyroid
T249 22576-22583 CHEBI:60311;CHEBI:60311;GO:0007179 denotes hormone
T250 22584-22593 GO:0007179 denotes signaling
T251 22719-22724 SO:0001867 denotes genes
T252 22925-22929 SO:0000704 denotes gene
T253 22934-22939 PR:000003671 denotes ACSS1
T254 22997-23001 SO:0000704 denotes gene
T255 23006-23010 PR:000001126 denotes CNR2
T256 23068-23072 SO:0000704 denotes gene
T257 23134-23141 SO:0000417 denotes modules
T258 23159-23166 PR:000009054 denotes insulin
T259 23193-23202 GO:0019221 denotes signaling
T260 23212-23216 CL:0000899 denotes Th17
T261 23217-23221 CL:0000899;GO:0030154 denotes cell
T262 23222-23237 GO:0030154 denotes differentiation
T263 23280-23285 SO:0001867 denotes genes
T264 23485-23489 SO:0000704 denotes gene
T265 23494-23500 PR:000005786 denotes COX7A1
T266 23561-23565 SO:0000704 denotes gene
T267 23570-23574 PR:000014305 denotes RRM1
T268 23633-23637 SO:0000704 denotes gene
T269 23642-23646 PR:000001126 denotes CNR2
T270 23707-23711 SO:0000704 denotes gene
T271 23716-23721 PR:000003671 denotes ACSS1
T272 23779-23783 SO:0000704 denotes gene
T273 23788-23793 PR:000001582 denotes FFAR1
T274 23844-23851 SO:0000417 denotes modules
T275 23869-23894 GO:0019722 denotes calcium signaling pathway
T276 24281-24290 CHEBI:36357;CHEBI:36357 denotes compounds
T277 24725-24730 CHEBI:23888;CHEBI:23888 denotes drugs
T278 24752-24760 SP_7 denotes COVID-19
T279 24910-24919 CHEBI:36357;CHEBI:36357 denotes compounds
T280 25088-25091 NCBITaxon:9606 denotes Man
T283 25326-25335 CHEBI:36357;CHEBI:36357 denotes compounds
T284 25384-25388 CHEBI:23888;CHEBI:23888 denotes drug
T285 25443-25452 CHEBI:36357;CHEBI:36357 denotes compounds
T286 25728-25737 CHEBI:36357;CHEBI:36357 denotes compounds
T287 25880-25884 CHEBI:23888;CHEBI:23888 denotes drug
T288 25931-25940 CHEBI:36357;CHEBI:36357 denotes compounds
T289 26004-26020 UBERON:0005409 denotes gastrointestinal
T290 26345-26354 CHEBI:36357;CHEBI:36357 denotes compounds
T291 26410-26415 CL_1 denotes Caco2
T292 26417-26423 CL_1 denotes Caco-2
T293 26442-26452 UBERON:0000160 denotes Intestinal
T294 26465-26470 SP_6;NCBITaxon:9606 denotes Human
T295 26550-26555 SP_6;NCBITaxon:9606 denotes Human
T296 26563-26574 UBERON:0000120 denotes Blood Brain
T297 26597-26600 UBERON:0001017 denotes CNS
T298 26602-26624 UBERON:0001017 denotes Central Nervous System
T299 26659-26663 PR:000013036 denotes OCT2
T300 26665-26670 UBERON:0002113 denotes Renal
T301 26671-26685 CHEBI:25697;CHEBI:25697;PR:000014988 denotes Organic Cation
T302 26686-26699 PR:000014988 denotes Transporter 2
T303 26752-26757 SP_6;NCBITaxon:9606 denotes Human
T304 26760-26764 PR:P11308 denotes hERG
T305 26771-26775 PR:P11308 denotes hERG
T306 26803-26807 UBERON:0000165 denotes Oral
T307 26808-26811 NCBITaxon:10114 denotes Rat
T308 26879-26881 UBERON:0001448 denotes MT
T309 27108-27117 CHEBI:36357;CHEBI:36357 denotes compounds
T310 27140-27148 SP_7 denotes COVID-19
T311 27169-27178 PG_2 denotes E protein
T312 27180-27183 CHEBI:24870;CHEBI:24870 denotes ion
T313 27204-27209 PR:000000125 denotes nsp13
T314 27241-27246 PR:000000125 denotes nsp13
T315 27304-27306 CHEBI:15379;CHEBI:15379 denotes O2
T342 27398-27407 CHEBI:36357;CHEBI:36357 denotes compounds
T343 27441-27445 UBERON:0000165 denotes oral
T344 27481-27487 CL_1 denotes Caco-2
T345 27538-27542 CHEBI:23888;CHEBI:23888 denotes drug
T346 27588-27597 CHEBI:36357;CHEBI:36357 denotes compounds
T347 27613-27619 UBERON:0000479 denotes tissue
T348 27633-27639 UBERON:0000479 denotes tissue
T349 27654-27660 UBERON:0001969 denotes plasma
T350 27742-27757 CHEBI:52217;CHEBI:52217 denotes pharmacological
T351 27829-27848 UBERON:0000120 denotes blood-brain barrier
T352 27850-27853 UBERON:0000120 denotes BBB
T353 27859-27881 UBERON:0001017 denotes central nervous system
T354 27883-27886 UBERON:0001017 denotes CNS
T355 27905-27914 CHEBI:36357;CHEBI:36357 denotes compounds
T356 27932-27937 UBERON:0002113 denotes renal
T357 27981-27986 UBERON:0002113 denotes renal
T358 27987-28001 CHEBI:25697;CHEBI:25697;PR:000014988 denotes organic cation
T359 28002-28015 PR:000014988 denotes transporter 2
T360 28017-28021 PR:000013036 denotes OCT2
T361 28036-28045 CHEBI:36357;CHEBI:36357 denotes compounds
T362 28105-28109 CHEBI:34018;CHEBI:34018 denotes AMES
T363 28144-28148 PR:P11308 denotes hERG
T364 28151-28160 CHEBI:35222;CHEBI:35222 denotes inhibitor
T365 28162-28166 PR:P11308 denotes hERG
T366 28170-28179 CHEBI:35222;CHEBI:35222 denotes inhibitor
T367 28181-28185 UBERON:0000165 denotes oral
T368 28186-28189 NCBITaxon:10114 denotes rat
T372 28308-28317 CHEBI:36357;CHEBI:36357 denotes compounds
T373 29038-29046 SP_7 denotes COVID-19
T374 29149-29158 CHEBI:36357;CHEBI:36357 denotes compounds
T375 29318-29323 PR:000000125 denotes nsp12
T376 29341-29346 PR:000000125 denotes nsp12
T377 29367-29372 PR:000000125 denotes nsp13
T378 29383-29391 SO:0000346 denotes ADP site
T379 29394-29399 PR:000000125 denotes nsp13
T380 29421-29426 PR:000000125 denotes nsp14
T381 29435-29440 PR:000000125 denotes nsp14
T382 29453-29458 PR:000000125 denotes nsp15
T383 29479-29484 PR:000000125 denotes nsp16
T384 29499-29508 PG_4 denotes N protein
T385 29519-29528 PG_2 denotes E protein
T386 29530-29533 CHEBI:24870;CHEBI:24870 denotes ion
T387 29705-29714 CHEBI:36357;CHEBI:36357 denotes compounds
T388 29757-29766 CHEBI:36357;CHEBI:36357 denotes compounds
T389 29812-29821 CHEBI:36357;CHEBI:36357 denotes compounds
T397 29886-29895 SP_7 denotes 2019-nCov
T398 30918-30926 SP_7 denotes COVID-19
T399 31386-31390 CHEBI:23888;CHEBI:23888 denotes drug
T400 31562-31566 CHEBI:23888;CHEBI:23888 denotes drug
T401 31657-31665 CHEBI:36357;CHEBI:36357 denotes compound
T402 31715-31724 PG_2 denotes E protein
T403 31726-31729 CHEBI:24870;CHEBI:24870 denotes ion
T404 32073-32081 CHEBI:36357;CHEBI:36357 denotes compound
T405 32131-32136 PR:000000125 denotes nsp13
T406 32203-32208 CHEBI:32988;CHEBI:32988 denotes Amide
T407 32381-32386 CHEBI:22563;CHEBI:22563 denotes anion
T408 32522-32530 CHEBI:36357;CHEBI:36357 denotes compound
T409 32722-32724 CHEBI:15379;CHEBI:15379 denotes O2
T410 32747-32755 CHEBI:36357;CHEBI:36357 denotes compound
T411 32868-32873 CHEBI:22563;CHEBI:22563 denotes anion
T412 32986-32994 CHEBI:36357;CHEBI:36357 denotes compound
T413 33054-33063 PG_4 denotes N protein
T414 33292-33297 PR:000000125 denotes nsp14
T415 33440-33448 CHEBI:36357;CHEBI:36357 denotes compound
T416 33506-33511 PR:000000125 denotes nsp15
T417 33652-33655 PR:P19339 denotes SX1
T418 33669-33677 CHEBI:36357;CHEBI:36357 denotes compound
T419 33733-33738 PR:000000125 denotes nsp14
T420 33837-33840 PR:P19339 denotes SX1
T421 33881-33886 PR:000000125 denotes nsp15
T422 34039-34047 CHEBI:36357;CHEBI:36357 denotes compound
T423 34107-34112 PR:000000125 denotes nsp16
T424 34198-34203 CHEBI:17478;CHEBI:17478 denotes alkyl
T425 34211-34216 CHEBI:22563;CHEBI:22563 denotes anion
T426 34346-34351 PR:000000125 denotes nsp12
T427 34452-34458 CHEBI:36916;CHEBI:36916 denotes cation
T428 34466-34471 CHEBI:22563;CHEBI:22563 denotes anion
T429 34560-34568 CHEBI:36357;CHEBI:36357 denotes compound
T430 34626-34631 PR:000000125 denotes nsp12
T431 34877-34886 CHEBI:36357;CHEBI:36357 denotes compounds
T432 34913-34921 SP_7 denotes COVID-19
T433 34943-34952 PG_4 denotes N protein
T434 34966-34969 PR:Q8K4K7 denotes MS1
T435 34974-34979 PR:000000125 denotes nsp14
T436 35000-35005 PR:000000125 denotes nsp15
T437 35029-35032 PR:P19339 denotes SX1
T438 35037-35042 PR:000000125 denotes nsp14
T439 35058-35061 PR:P19339 denotes SX1
T440 35066-35071 PR:000000125 denotes nsp15
T441 35103-35108 PR:000000125 denotes nsp16
T442 35134-35139 PR:000000125 denotes nsp12
T443 35171-35176 PR:000000125 denotes nsp12
T457 35295-35299 G_3;PG_10;PR:000003622 denotes ACE2
T458 35304-35309 PR:000001324 denotes CD147
T459 35310-35320 GO:0010467 denotes expression
T460 35328-35335 UBERON:0000479 denotes tissues
T461 35343-35353 GO:0010467 denotes expression
T462 35354-35359 SO:0000704 denotes genes
T463 35366-35375 SP_7 denotes 2019-nCov
T464 35392-35399 UBERON:0000479 denotes tissues
T465 35404-35410 UBERON:0000062 denotes organs
T466 35419-35423 G_3;PG_10;PR:000003622 denotes ACE2
T467 35428-35433 PR:000001324 denotes CD147
T468 35467-35477 GO:0010467 denotes expression
T469 35498-35502 G_3;PG_10;PR:000003622 denotes ACE2
T470 35507-35512 PR:000001324 denotes CD147
T471 35523-35530 UBERON:0000479 denotes tissues
T472 35564-35574 GO:0010467 denotes expression
T473 35575-35582 UBERON:0000479 denotes tissues
T474 35586-35590 G_3;PG_10;PR:000003622 denotes ACE2
T475 35605-35610 UBERON:0002116 denotes ileum
T476 35612-35618 UBERON:0000473 denotes testis
T477 35620-35628 UBERON:0004877 denotes visceral
T478 35630-35637 UBERON:0003688 denotes omentum
T479 35640-35654 UBERON:0002084 denotes left ventricle
T480 35659-35672 UBERON:0001225 denotes kidney cortex
T481 35710-35714 UBERON:0002048 denotes lung
T482 35730-35740 GO:0010467 denotes expression
T483 35741-35748 UBERON:0000479 denotes tissues
T484 35752-35757 PR:000001324 denotes CD147
T485 35763-35769 UBERON:0000473 denotes testis
T486 35771-35779 UBERON:0004877 denotes visceral
T487 35781-35788 UBERON:0003688 denotes omentum
T488 35791-35805 UBERON:0002084 denotes left ventricle
T489 35807-35812 UBERON:0000947 denotes aorta
T490 35814-35830 UBERON:0006618 denotes atrial appendage
T491 35847-35858 CL:0000057 denotes fibroblasts
T492 35927-35936 SP_7 denotes 2019-nCov
T493 35957-35967 GO:0010467 denotes expression
T494 35968-35973 SO:0000704 denotes genes
T495 35977-35981 G_3;PG_10;PR:000003622 denotes ACE2
T496 35990-36000 GO:0010467 denotes expression
T497 36001-36006 SO:0000704 denotes genes
T498 36010-36015 PR:000001324 denotes CD147
T499 36098-36108 GO:0010467 denotes expression
T500 36109-36114 SO:0000704 denotes genes
T501 36118-36122 G_3;PG_10;PR:000003622 denotes ACE2
T502 36126-36133 UBERON:0001155;CL:0011108 denotes colonic
T503 36134-36144 CL:0011108;UBERON:0002424 denotes epithelial
T504 36145-36150 CL:0011108 denotes cells
T505 36303-36311 SP_7 denotes COVID-19
T506 36327-36336 SP_7 denotes 2019-nCov
T507 36349-36353 G_3;PG_10;PR:000003622 denotes ACE2
T508 36358-36363 PR:000001324 denotes CD147
T538 36391-36395 G_3;PG_10;PR:000003622 denotes ACE2
T539 36400-36405 PR:000001324 denotes CD147
T540 36406-36416 GO:0010467 denotes expression
T541 36424-36431 UBERON:0000479 denotes tissues
T542 36439-36449 GO:0010467 denotes expression
T543 36450-36455 SO:0000704 denotes genes
T544 36474-36478 G_3;PG_10;PR:000003622 denotes ACE2
T545 36483-36488 PR:000001324 denotes CD147
T546 36489-36499 GO:0010467 denotes expression
T547 36510-36517 UBERON:0000479 denotes tissues
T548 36523-36533 GO:0010467 denotes expression
T549 36616-36626 GO:0010467 denotes expression
T550 36627-36634 UBERON:0000479 denotes tissues
T551 36706-36710 G_3;PG_10;PR:000003622 denotes ACE2
T552 36714-36724 GO:0010467 denotes expression
T553 36725-36730 SO:0000704 denotes genes
T554 36732-36736 G_3;PG_10;PR:000003622 denotes ACE2
T555 36748-36753 PR:000001324 denotes CD147
T556 36757-36767 GO:0010467 denotes expression
T557 36768-36773 SO:0000704 denotes genes
T558 36775-36780 PR:000001324 denotes CD147
T559 36796-36800 G_3;PG_10;PR:000003622 denotes ACE2
T560 36804-36814 GO:0010467 denotes expression
T561 36815-36820 SO:0000704 denotes genes
T562 36824-36831 UBERON:0001155;CL:0011108 denotes colonic
T563 36832-36842 CL:0011108;UBERON:0000483 denotes epithelial
T564 36843-36848 CL:0011108 denotes cells
T565 36850-36854 G_3;PG_10;PR:000003622 denotes ACE2
T566 36855-36862 UBERON:0001155 denotes colonic
T567 37294-37298 CHEBI:23888;CHEBI:23888 denotes drug
T568 37328-37336 SP_7 denotes COVID-19
T569 37484-37492 SP_7 denotes COVID-19
T570 37603-37611 SP_7 denotes COVID-19
T578 37975-37983 SP_7 denotes COVID-19
T579 38019-38023 CHEBI:23888;CHEBI:23888 denotes drug
T580 38146-38150 CHEBI:23888;CHEBI:23888 denotes drug
T581 38606-38615 SP_7 denotes 2019-nCov
T582 39499-39507 SP_7 denotes COVID-19
T583 39659-39663 CHEBI:23888;CHEBI:23888 denotes drug
T584 39680-39685 PR:000005188 denotes Cdc20
T585 39687-39691 PR:000009030 denotes Ido1
T586 39693-39697 PR:000000017 denotes Ifng
T587 39699-39703 PR:000001471 denotes Il10
T588 39710-39716 PR:000001548 denotes Ptger4
T589 39718-39722 PR:000001944 denotes Spi1
T590 39724-39727 PR:000000134 denotes Tnf
T591 39737-39741 CHEBI:23888;CHEBI:23888 denotes drug
T592 39764-39772 SP_7 denotes COVID-19
T593 39885-39903 UBERON:0000160 denotes inflammatory bowel
T594 39913-39931 GO:0007259 denotes JAK-STAT signaling
T596 39979-39987 SP_7 denotes COVID-19
T597 40400-40411 NCBITaxon:11118 denotes coronavirus
T598 40413-40422 SP_7 denotes 2019-nCov
T599 40454-40458 UBERON:0002048 denotes lung
T600 40463-40476 UBERON:0002405 denotes immune system
T601 40520-40531 UBERON:0001004 denotes respiratory
T602 40596-40601 GO:0016265 denotes death
T603 40657-40662 UBERON:0000062 denotes organ
T604 40723-40728 CHEBI:23888;CHEBI:23888 denotes drugs
T605 40765-40773 SP_7 denotes COVID-19
T606 40824-40828 CHEBI:23888;CHEBI:23888 denotes drug
T607 41013-41021 SP_7 denotes COVID-19
T608 41230-41241 NCBITaxon:11118 denotes coronavirus
T609 41319-41327 SP_7 denotes COVID-19
T610 41339-41351 CHEBI:52217;CHEBI:52217 denotes pharmacology
T611 41744-41749 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T612 41750-41767 GO:0006629 denotes metabolic process
T613 41769-41774 CHEBI:18059;CHEBI:18059 denotes lipid
T614 41790-41798 CHEBI:36357;CHEBI:36357 denotes molecule
T615 41799-41816 GO:0044281 denotes metabolic process
T616 41822-41841 GO:0042592 denotes homeostatic process
T617 41879-41884 NCBITaxon:10239 denotes viral
T618 41902-41911 GO:0008152 denotes metabolic
T619 41988-41993 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T620 41994-42003 GO:0006629 denotes metabolic
T621 42044-42049 GO:0006260;NCBITaxon:10239 denotes virus
T622 42050-42061 GO:0006260 denotes replication
T623 42180-42185 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T624 42186-42196 GO:0006629 denotes metabolism
T625 42215-42231 UBERON:0000949 denotes endocrine system
T626 42557-42568 GO:0042592 denotes homeostasis
T627 42572-42582 GO:0008152 denotes metabolism
T628 42698-42711 UBERON:0002405 denotes immune system
T629 42721-42742 GO:0005783 denotes endoplasmic reticulum
T630 42744-42763 GO:0007267 denotes cell-cell signaling
T631 42801-42814 UBERON:0004237;GO:0014829 denotes smooth muscle
T632 42815-42826 GO:0014829 denotes contraction
T633 42828-42849 CHEBI:67079;CHEBI:67079 denotes inflammatory mediator
T634 42850-42860 GO:0065007 denotes regulation
T635 42878-42892 UBERON:0001133;GO:0060048 denotes cardiac muscle
T636 42893-42904 GO:0060048 denotes contraction
T637 43340-43348 SP_7 denotes COVID-19
T638 43390-43399 GO:0010467 denotes expressed
T639 43400-43404 CHEBI:23888;CHEBI:23888 denotes drug
T640 43421-43426 PR:000005188 denotes Cdc20
T641 43428-43432 PR:000009030 denotes Ido1
T642 43434-43438 PR:000000017 denotes Ifng
T643 43440-43444 PR:000001471 denotes Il10
T644 43446-43449 PR:000001393 denotes Il6
T645 43451-43457 PR:000001548 denotes Ptger4
T646 43459-43463 PR:000001944 denotes Spi1
T647 43496-43505 NCBITaxon:2 denotes bacterial
T648 43510-43515 NCBITaxon:10239 denotes viral
T649 43537-43550 UBERON:0002405 denotes immune system
T650 43629-43638 SP_7 denotes 2019-nCov
T651 43658-43664 UBERON:0000062 denotes organs
T652 43688-43693 UBERON:0002107 denotes liver
T653 43700-43708 UBERON:0001264 denotes pancreas
T654 43715-43721 UBERON:0002113 denotes kidney
T655 43728-43734 UBERON:0000341 denotes throat
T656 43739-43745 UBERON:0001052 denotes rectum
T657 43804-43808 G_3;PG_10;PR:000003622 denotes ACE2
T658 43822-43829 UBERON:0000479 denotes tissues
T659 43883-43887 G_3;PG_10;PR:000003622 denotes ACE2
T660 43899-43908 GO:0010467 denotes expressed
T661 43921-43926 UBERON:0002116 denotes ileum
T662 43928-43934 UBERON:0000473 denotes testis
T663 43936-43943 UBERON:0001013 denotes adipose
T664 43944-43952 UBERON:0004877 denotes visceral
T665 43953-43960 UBERON:0003688 denotes omentum
T666 43962-43982 UBERON:0002084 denotes heart left ventricle
T667 43984-43997 UBERON:0001225 denotes kidney cortex
T668 44002-44009 UBERON:0002046 denotes thyroid
T669 44063-44072 SP_7 denotes 2019-nCov
T670 44088-44092 G_3;PG_10;PR:000003622 denotes ACE2
T671 44101-44106 SO:0000704 denotes genes
T672 44172-44180 SP_7 denotes COVID-19
T673 44313-44321 SP_7 denotes COVID-19
T674 44386-44404 UBERON:0000160 denotes inflammatory bowel
T675 44434-44443 UBERON:0002048 denotes pulmonary
T676 44453-44465 UBERON:0000160 denotes intrahepatic
T677 44577-44581 CHEBI:23888;CHEBI:23888 denotes drug
T678 44621-44625 CHEBI:23888;CHEBI:23888;GO:0017144 denotes drug
T679 44626-44637 GO:0032502 denotes development
T680 44699-44708 CHEBI:36357;CHEBI:36357 denotes compounds
T681 44820-44826 CHEBI:30563;CHEBI:30563 denotes silico
T682 44827-44831 CHEBI:23888;CHEBI:23888 denotes drug
T683 44863-44879 UBERON:0005409 denotes gastrointestinal
T684 45244-45253 CHEBI:36357;CHEBI:36357 denotes compounds
T685 45292-45301 SP_7 denotes 2019-nCov
T686 45368-45376 SP_7 denotes COVID-19
T687 45506-45510 GO:0018995 denotes host
T688 45520-45529 SO:0000276 denotes microRNAs
T689 45531-45537 SO:0000276 denotes miRNAs
T690 45559-45569 GO:0065007 denotes regulation
T691 45573-45578 NCBITaxon:10239 denotes virus
T692 45655-45661 PR:000010182 denotes MIR301
T693 45681-45687 PR:000010182 denotes MIR183
T694 45860-45869 SO:0000646 denotes microRNAs
T695 45885-45893 SP_7 denotes COVID-19
T696 45971-45982 GO:0006260 denotes replication
T697 45994-46001 NCBITaxon:10239 denotes viruses
T698 46013-46018 SP_6;NCBITaxon:9606 denotes human
T699 46022-46023 NCBITaxon:10376 denotes -
T700 46026-46042 NCBITaxon:9258 denotes papillomaviruses
T701 46044-46049 SP_6;NCBITaxon:9606 denotes human
T702 46050-46065 NCBITaxon:10358 denotes cytomegalovirus
T703 46067-46071 NCBITaxon:10358 denotes HCMV
T704 46074-46080 NCBITaxon:9606 denotes herpes
T705 46081-46094 NCBITaxon:10376 denotes simplex virus
T706 46096-46099 NCBITaxon:10298 denotes HSV
T707 46112-46115 NCBITaxon:10298 denotes HSV
T708 46174-46178 PR:000005265 denotes CDK7
T709 46252-46260 GO:0065007 denotes regulate
T710 46261-46272 GO:0006260 denotes replication
T711 46276-46284 SP_7 denotes COVID-19
T712 46285-46292 NCBITaxon:10239 denotes viruses
T713 46297-46301 PR:000005265 denotes CDK7
T714 46311-46321 GO:0007049 denotes cell cycle
T715 46411-46419 GO:0065007 denotes regulate
T716 46420-46431 CHEBI:16113;CHEBI:16113;GO:0042632 denotes cholesterol
T717 46432-46443 GO:0042632 denotes homeostasis
T718 46484-46493 GO:0065007 denotes regulated
T719 46506-46515 NCBITaxon:7719 denotes influenza
T720 46516-46521 NCBITaxon:10239 denotes virus
T721 46646-46654 GO:0065007 denotes regulate
T722 46655-46664 GO:0008152 denotes metabolic
T723 46707-46715 SP_7 denotes COVID-19
T724 46716-46721 NCBITaxon:10239 denotes virus
T725 46783-46791 SP_7 denotes COVID-19
T726 47002-47006 SP_10 denotes SARS
T727 47052-47060 SP_7 denotes COVID-19
T728 47082-47090 SP_7 denotes COVID-19
T729 47131-47139 SP_7 denotes COVID-19
T730 47285-47297 CHEBI:52217;CHEBI:52217 denotes pharmacology
T731 47357-47365 SP_7 denotes COVID-19
T732 47462-47470 SP_7 denotes COVID-19
T733 47668-47674 SO:0000276 denotes miRNAs
T734 47729-47737 SP_7 denotes COVID-19
T735 47836-47844 SP_7 denotes COVID-19
T77241 19-27 SP_7 denotes COVID-19
T25522 71-76 NCBITaxon:10239 denotes viral
T26726 109-118 GO:0008152 denotes metabolic
T22563 221-229 SP_7 denotes COVID-19
T45473 239-244 NCBITaxon:10239 denotes viral
T92290 250-263 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T26450 268-277 GO:0008152 denotes metabolic
T9512 356-365 SP_7 denotes 2019-nCov
T7610 428-436 SP_7 denotes COVID-19
T11 2324-2329 NCBITaxon:10239 denotes viral
T12 2335-2348 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T13 2362-2371 GO:0008152 denotes metabolic
T14 45292-45301 SP_7 denotes 2019-nCov

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 888-893 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T2 1275-1283 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T3 1815-1823 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T4 2057-2070 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T5 3288-3293 Body_part denotes Semen http://purl.org/sig/ont/fma/fma62966
T6 4063-4068 Body_part denotes Semen http://purl.org/sig/ont/fma/fma62966
T7 4521-4527 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T8 4894-4900 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T9 8034-8038 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T10 8357-8360 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T11 8755-8763 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T12 9078-9085 Body_part denotes Genomes http://purl.org/sig/ont/fma/fma84116
T13 10218-10222 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 10245-10249 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T15 10303-10308 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T16 10309-10314 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T17 10327-10349 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T18 10556-10560 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T19 10891-10899 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T20 10959-10962 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T21 10985-10988 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T22 11052-11056 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T23 11125-11132 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T24 11148-11155 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T25 11194-11201 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T26 11251-11254 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T27 11271-11274 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T28 11317-11321 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T29 11500-11508 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T30 11549-11556 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T31 11652-11659 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T32 11687-11694 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T33 12020-12036 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T34 12031-12036 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T35 12067-12075 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T36 12212-12220 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T37 12968-12977 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T38 14741-14749 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T39 18262-18267 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T40 18287-18292 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T41 18388-18392 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T42 18660-18675 Body_part denotes steroid hormone http://purl.org/sig/ont/fma/fma83353
T43 18714-18722 Body_part denotes arginine http://purl.org/sig/ont/fma/fma82763
T44 18727-18734 Body_part denotes proline http://purl.org/sig/ont/fma/fma82761
T45 18935-18943 Body_part denotes prostate http://purl.org/sig/ont/fma/fma9600
T46 18986-18991 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T47 19170-19177 Body_part denotes Alanine http://purl.org/sig/ont/fma/fma82749
T48 19219-19240 Body_part denotes membrane organization http://purl.org/sig/ont/fma/fma7145
T49 19273-19276 Body_part denotes eye http://purl.org/sig/ont/fma/fma54448
T50 20968-20975 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T51 21223-21227 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T52 21299-21303 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T53 21374-21378 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T54 22060-22064 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T55 22206-22211 Body_part denotes Notch http://purl.org/sig/ont/fma/fma75036
T56 22479-22483 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T57 22568-22575 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T58 22576-22583 Body_part denotes hormone http://purl.org/sig/ont/fma/fma12278
T59 22925-22929 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T60 22997-23001 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T61 23068-23072 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T62 23159-23166 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T63 23217-23221 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T64 23485-23489 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T65 23561-23565 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T66 23633-23637 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T67 23707-23711 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T68 23779-23783 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T69 24397-24405 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T70 24468-24476 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T71 24536-24544 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T72 24605-24613 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T73 24678-24686 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T74 26442-26452 Body_part denotes Intestinal http://purl.org/sig/ont/fma/fma7199
T75 26473-26477 Body_part denotes Skin http://purl.org/sig/ont/fma/fma7163
T76 26479-26483 Body_part denotes Skin http://purl.org/sig/ont/fma/fma7163
T77 26563-26568 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T78 26569-26574 Body_part denotes Brain http://purl.org/sig/ont/fma/fma50801
T79 26597-26600 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T80 26602-26624 Body_part denotes Central Nervous System http://purl.org/sig/ont/fma/fma55675
T81 26610-26624 Body_part denotes Nervous System http://purl.org/sig/ont/fma/fma7157
T82 26859-26863 Body_part denotes Skin http://purl.org/sig/ont/fma/fma7163
T83 27149-27157 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T84 27171-27178 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85 27488-27492 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T86 27515-27519 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T87 27613-27619 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T88 27633-27639 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T89 27654-27660 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T90 27829-27834 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T91 27835-27840 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T92 27859-27881 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T93 27883-27886 Body_part denotes CNS http://purl.org/sig/ont/fma/fma55675
T94 28229-28233 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163
T95 29295-29303 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T96 29335-29338 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T97 29361-29364 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T98 29428-29432 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T99 29501-29508 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T100 29521-29528 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T101 29896-29904 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T102 30100-30103 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T103 30172-30175 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T104 30379-30383 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T105 30663-30670 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T106 30733-30740 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T107 31717-31724 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T108 33056-33063 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T109 33299-33303 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T110 34366-34369 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T111 34643-34646 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T112 34922-34930 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T113 34945-34952 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T114 34981-34985 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T115 35154-35157 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T116 35188-35191 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T117 35328-35335 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T118 35392-35399 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T119 35523-35530 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T120 35575-35582 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T121 35596-35610 Body_part denotes terminal ileum http://purl.org/sig/ont/fma/fma14966
T122 35612-35618 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210
T123 35630-35637 Body_part denotes omentum http://purl.org/sig/ont/fma/fma14650
T124 35640-35654 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T125 35659-35665 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T126 35666-35672 Body_part denotes cortex http://purl.org/sig/ont/fma/fma61109
T127 35710-35714 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T128 35741-35748 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T129 35763-35769 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210
T130 35781-35788 Body_part denotes omentum http://purl.org/sig/ont/fma/fma14650
T131 35791-35805 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T132 35807-35812 Body_part denotes aorta http://purl.org/sig/ont/fma/fma3734
T133 35847-35858 Body_part denotes fibroblasts http://purl.org/sig/ont/fma/fma63877
T134 36042-36050 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T135 36077-36085 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T136 36134-36150 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T137 36145-36150 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T138 36424-36431 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T139 36510-36517 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T140 36627-36634 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T141 36653-36661 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T142 36832-36848 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T143 36843-36848 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T144 36935-36943 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T145 37000-37004 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T146 37114-37122 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T147 38616-38624 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T148 38805-38808 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T149 38863-38866 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T150 39042-39046 Body_part denotes ExoN http://purl.org/sig/ont/fma/fma84120
T151 39286-39293 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 39346-39353 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T153 39824-39832 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T154 39833-39841 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T155 39898-39903 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T156 40454-40458 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T157 40463-40476 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T158 40657-40662 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T159 41744-41749 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T160 41769-41774 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T161 41988-41993 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T162 42180-42185 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T163 42215-42231 Body_part denotes endocrine system http://purl.org/sig/ont/fma/fma9668
T164 42698-42711 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T165 42721-42742 Body_part denotes endoplasmic reticulum http://purl.org/sig/ont/fma/fma63842
T166 42744-42748 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T167 42749-42753 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T168 42808-42814 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T169 42886-42892 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T170 43527-43535 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T171 43537-43550 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T172 43688-43693 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T173 43700-43708 Body_part denotes pancreas http://purl.org/sig/ont/fma/fma7198
T174 43715-43721 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T175 43728-43734 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T176 43739-43745 Body_part denotes rectum http://purl.org/sig/ont/fma/fma14544
T177 43822-43829 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T178 43912-43926 Body_part denotes terminal ileum http://purl.org/sig/ont/fma/fma14966
T179 43928-43934 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210
T180 43953-43960 Body_part denotes omentum http://purl.org/sig/ont/fma/fma14650
T181 43962-43967 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T182 43968-43982 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T183 43984-43990 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T184 43991-43997 Body_part denotes cortex http://purl.org/sig/ont/fma/fma61109
T185 44002-44009 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T186 44399-44404 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T187 45330-45338 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T188 46019-46022 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T189 46311-46315 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T190 46326-46329 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T191 47099-47108 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 2057-2070 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T2 3288-3293 Body_part denotes Semen http://purl.obolibrary.org/obo/UBERON_0001968
T3 4063-4068 Body_part denotes Semen http://purl.obolibrary.org/obo/UBERON_0001968
T4 4218-4235 Body_part denotes surface structure http://purl.obolibrary.org/obo/UBERON_0003102
T5 4521-4527 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T6 4894-4900 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T7 10245-10249 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T8 10303-10322 Body_part denotes blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T9 10303-10308 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T10 10309-10314 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T11 10327-10349 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T12 10335-10349 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T13 10556-10560 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T14 18986-18991 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T15 19219-19240 Body_part denotes membrane organization http://purl.obolibrary.org/obo/UBERON_0000094
T16 19273-19276 Body_part denotes eye http://purl.obolibrary.org/obo/UBERON_0000970
T17 22568-22575 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T18 26473-26477 Body_part denotes Skin http://purl.obolibrary.org/obo/UBERON_0000014
T19 26479-26483 Body_part denotes Skin http://purl.obolibrary.org/obo/UBERON_0000014
T20 26563-26582 Body_part denotes Blood Brain Barrier http://purl.obolibrary.org/obo/UBERON_0000120
T21 26597-26600 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T22 26602-26624 Body_part denotes Central Nervous System http://purl.obolibrary.org/obo/UBERON_0001017
T23 26859-26863 Body_part denotes Skin http://purl.obolibrary.org/obo/UBERON_0000014
T24 27515-27519 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T25 27613-27619 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T26 27633-27639 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T27 27829-27848 Body_part denotes blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T28 27829-27834 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T29 27835-27840 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T30 27859-27881 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T31 27867-27881 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T32 27883-27886 Body_part denotes CNS http://purl.obolibrary.org/obo/UBERON_0001017
T33 28229-28233 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014
T34 35404-35410 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T35 35605-35610 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T36 35612-35618 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473
T37 35630-35637 Body_part denotes omentum http://purl.obolibrary.org/obo/UBERON_0003688
T38 35659-35665 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T39 35666-35672 Body_part denotes cortex http://purl.obolibrary.org/obo/UBERON_0001851
T40 35710-35714 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T41 35763-35769 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473
T42 35781-35788 Body_part denotes omentum http://purl.obolibrary.org/obo/UBERON_0003688
T43 35807-35812 Body_part denotes aorta http://purl.obolibrary.org/obo/UBERON_0000947
T44 35821-35830 Body_part denotes appendage http://purl.obolibrary.org/obo/UBERON_0000026
T45 40454-40458 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T46 40463-40476 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T47 40657-40662 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T48 42215-42231 Body_part denotes endocrine system http://purl.obolibrary.org/obo/UBERON_0000949
T49 42698-42711 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T50 43537-43550 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T51 43658-43664 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T52 43688-43693 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T53 43700-43708 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264
T54 43715-43721 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T55 43728-43734 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T56 43739-43745 Body_part denotes rectum http://purl.obolibrary.org/obo/UBERON_0001052
T57 43921-43926 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T58 43928-43934 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473
T59 43953-43960 Body_part denotes omentum http://purl.obolibrary.org/obo/UBERON_0003688
T60 43962-43982 Body_part denotes heart left ventricle http://purl.obolibrary.org/obo/UBERON_0002084
T61 43962-43967 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T62 43984-43990 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T63 43991-43997 Body_part denotes cortex http://purl.obolibrary.org/obo/UBERON_0001851
T64 44002-44009 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 19-27 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 28-34 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T3 221-229 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 428-436 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 544-552 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 1064-1085 Disease denotes inflammatory diseases http://purl.obolibrary.org/obo/MONDO_0021166
T7 1087-1093 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T8 1095-1132 Disease denotes chronic obstructive pulmonary Disease http://purl.obolibrary.org/obo/MONDO_0005002
T9 1242-1251 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T10 1855-1863 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1920-1928 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 2182-2190 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 2588-2613 Disease denotes corona virus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T14 2615-2623 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 2994-3004 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T16 3005-3014 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T17 3066-3070 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 3709-3717 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 4144-4155 Disease denotes common cold http://purl.obolibrary.org/obo/MONDO_0005709
T20 4168-4177 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T21 4178-4194 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T22 4459-4462 Disease denotes flu http://purl.obolibrary.org/obo/MONDO_0005812
T23 4478-4484 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T24 4486-4498 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T25 4500-4511 Disease denotes tonsillitis http://purl.obolibrary.org/obo/MONDO_0001039
T26 4516-4527 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T27 5396-5404 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 5574-5582 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 6325-6333 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T30 6409-6417 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 6540-6550 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T32 6551-6560 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T33 6747-6755 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 10659-10667 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T35 10677-10685 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 10788-10796 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 11484-11492 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 11896-11905 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T39 12293-12301 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 12362-12370 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 12909-12917 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 12981-12989 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 13033-13037 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T44 13172-13180 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T45 13524-13532 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 18904-18908 Disease denotes acne http://purl.obolibrary.org/obo/MONDO_0011438
T47 18910-18926 Disease denotes Behcet'S disease http://purl.obolibrary.org/obo/MONDO_0007191
T48 18928-18955 Disease denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/MONDO_0010811
T49 18944-18955 Disease denotes hyperplasia http://purl.obolibrary.org/obo/MONDO_0005043
T50 18957-18981 Disease denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/MONDO_0019072
T51 18970-18981 Disease denotes cholestasis http://purl.obolibrary.org/obo/MONDO_0001751
T52 18986-18998 Disease denotes brain injury http://purl.obolibrary.org/obo/MONDO_0043510
T53 18992-18998 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T54 19245-19265 Disease denotes parasitic infections http://purl.obolibrary.org/obo/MONDO_0005135
T55 19314-19326 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T56 19430-19451 Disease denotes inflammatory diseases http://purl.obolibrary.org/obo/MONDO_0021166
T57 22154-22174 Disease denotes huntington's disease http://purl.obolibrary.org/obo/MONDO_0007739
T58 24752-24760 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T59 27140-27148 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T60 29038-29046 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T61 30918-30926 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 34913-34921 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 35914-35923 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T64 36021-36030 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T65 36303-36311 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 36338-36347 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T67 36695-36704 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T68 37328-37336 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 37484-37492 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 37603-37611 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 37975-37983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T72 39499-39507 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 39764-39772 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 39797-39822 Disease denotes Graft-versus-host disease http://purl.obolibrary.org/obo/MONDO_0013730
T75 39864-39870 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T76 39872-39881 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T77 39885-39911 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T78 39979-39987 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T79 40412-40433 Disease denotes (2019-nCov) infection http://purl.obolibrary.org/obo/MONDO_0100096
T80 40424-40433 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T81 40492-40501 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T82 40514-40549 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T83 40520-40549 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T84 40551-40555 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T85 40765-40773 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 41013-41021 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T87 41193-41202 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T88 41319-41327 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T89 42533-42542 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T90 43340-43348 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T91 43700-43708 Disease denotes pancreas http://purl.obolibrary.org/obo/MONDO_0021040
T92 44074-44083 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T93 44172-44180 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 44313-44321 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 44355-44376 Disease denotes inflammatory diseases http://purl.obolibrary.org/obo/MONDO_0021166
T96 44378-44384 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T97 44386-44412 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T98 44414-44451 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T99 44434-44451 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T100 44453-44477 Disease denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/MONDO_0019072
T101 44466-44477 Disease denotes cholestasis http://purl.obolibrary.org/obo/MONDO_0001751
T102 44487-44494 Disease denotes ileitis http://purl.obolibrary.org/obo/MONDO_0000709
T103 45368-45376 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 45573-45588 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T105 45579-45588 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T106 45885-45893 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 46074-46088 Disease denotes herpes simplex http://purl.obolibrary.org/obo/MONDO_0004609
T108 46276-46284 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 46451-46463 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T110 46501-46515 Disease denotes H1N1 influenza http://purl.obolibrary.org/obo/MONDO_0005460
T111 46506-46515 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T112 46516-46531 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T113 46522-46531 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T114 46707-46715 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T115 46716-46731 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T116 46722-46731 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T117 46783-46791 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T118 47002-47006 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T119 47052-47060 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 47082-47090 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 47131-47139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T122 47357-47365 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 47462-47470 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T124 47729-47737 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 47836-47844 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 96-104 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T2 166-167 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T3 480-481 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 514-517 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T5 576-582 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T6 878-886 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T7 983-992 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T8 1016-1025 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T9 1383-1389 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T10 1527-1531 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T11 1656-1658 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T12 1697-1700 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T13 1697-1700 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T14 2057-2070 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T15 2072-2081 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T16 2159-2160 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 2205-2206 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T18 2349-2357 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T19 2595-2600 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T20 2634-2639 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T21 2640-2643 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T22 2644-2645 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 2751-2754 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T24 2755-2756 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 2870-2871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 2931-2936 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T27 2967-2970 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T28 2971-2972 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 3019-3022 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T30 3029-3030 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T31 3176-3183 http://purl.obolibrary.org/obo/UBERON_0000982 denotes jointly
T32 3176-3183 http://purl.obolibrary.org/obo/UBERON_0004905 denotes jointly
T33 3191-3192 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 3772-3773 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T35 4105-4108 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T36 4178-4183 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 4413-4414 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T38 4500-4511 http://purl.obolibrary.org/obo/UBERON_0002372 denotes tonsillitis
T39 4828-4829 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 4894-4900 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T41 4894-4900 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T42 4894-4900 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T43 5077-5084 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T44 5136-5137 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 5463-5464 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 5706-5707 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 5809-5810 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 6279-6281 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T49 6677-6678 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 6759-6760 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51 6872-6873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 6956-6957 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 7211-7219 http://purl.obolibrary.org/obo/CLO_0001279 denotes 30 % [15
T54 7460-7465 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T55 7473-7479 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T56 7697-7700 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes pan
T57 8034-8038 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T58 8323-8325 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T59 8346-8351 http://purl.obolibrary.org/obo/CLO_0050421 denotes chord
T60 8469-8476 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T61 8856-8868 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Homo sapiens
T62 8898-8899 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 9068-9073 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T64 9087-9096 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T65 9311-9317 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T66 9850-9856 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T67 9943-9949 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T68 10174-10176 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T69 10211-10222 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2 cell
T70 10245-10249 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T71 10245-10249 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T72 10245-10249 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T73 10245-10249 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T74 10245-10249 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T75 10303-10308 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T76 10303-10308 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T77 10309-10314 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T78 10309-10314 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T79 10327-10349 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T80 10327-10349 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T81 10327-10349 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T82 10556-10560 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T83 10556-10560 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T84 10556-10560 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T85 10556-10560 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T86 10556-10560 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T87 11575-11580 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T88 11661-11662 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 11763-11768 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T90 11917-11922 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T91 11995-12000 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T92 12012-12019 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonic
T93 12020-12030 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T94 12031-12036 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T95 12991-12993 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T96 13024-13029 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T97 13899-13905 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T98 14099-14100 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 14210-14212 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T100 14524-14525 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T101 14538-14539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T102 15763-15765 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T103 18014-18020 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T104 18044-18045 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T105 18058-18059 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T106 18160-18162 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T107 18252-18260 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T108 18357-18363 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T109 18375-18392 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity and cell
T110 18600-18609 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T111 18695-18704 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T112 18775-18776 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T113 18986-18991 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T114 18986-18991 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T115 19219-19227 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T116 19228-19240 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T117 19273-19276 http://www.ebi.ac.uk/efo/EFO_0000827 denotes eye
T118 19384-19392 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T119 19467-19470 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T120 19658-19659 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T121 19667-19668 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T122 19741-19742 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T123 19877-19878 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T124 20164-20166 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4C
T125 20255-20260 http://purl.obolibrary.org/obo/CLO_0050421 denotes Chord
T126 20471-20477 http://purl.obolibrary.org/obo/CLO_0050421 denotes Chords
T127 20529-20530 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T128 20539-20540 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T129 20818-20823 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T130 21066-21067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 21131-21132 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T132 21223-21227 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T133 21299-21303 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T134 21352-21354 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T135 21374-21378 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T136 21513-21522 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T137 21771-21772 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T138 21780-21781 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T139 21850-21855 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T140 22060-22064 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T141 22212-22221 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T142 22271-22276 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T143 22479-22483 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T144 22584-22593 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T145 22617-22626 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T146 22719-22724 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T147 22925-22929 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T148 22997-23001 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T149 23068-23072 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T150 23159-23166 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T151 23193-23202 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T152 23217-23221 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T153 23280-23285 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T154 23485-23489 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T155 23561-23565 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T156 23633-23637 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T157 23685-23687 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T158 23707-23711 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T159 23779-23783 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T160 23877-23886 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T161 23905-23914 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T162 24515-24517 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T163 24762-24763 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 25113-25114 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T165 25122-25123 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T166 25903-25904 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T167 26106-26107 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T168 26127-26128 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T169 26410-26415 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco2
T170 26410-26415 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco2
T171 26410-26415 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco2
T172 26410-26415 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco2
T173 26417-26423 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T174 26417-26423 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T175 26417-26423 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T176 26417-26423 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T177 26442-26452 http://purl.obolibrary.org/obo/UBERON_0000160 denotes Intestinal
T178 26442-26452 http://www.ebi.ac.uk/efo/EFO_0000834 denotes Intestinal
T179 26465-26470 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T180 26473-26477 http://purl.obolibrary.org/obo/UBERON_0000014 denotes Skin
T181 26473-26477 http://purl.obolibrary.org/obo/UBERON_0001003 denotes Skin
T182 26473-26477 http://purl.obolibrary.org/obo/UBERON_0002097 denotes Skin
T183 26473-26477 http://purl.obolibrary.org/obo/UBERON_0002199 denotes Skin
T184 26473-26477 http://www.ebi.ac.uk/efo/EFO_0000962 denotes Skin
T185 26479-26483 http://purl.obolibrary.org/obo/UBERON_0000014 denotes Skin
T186 26479-26483 http://purl.obolibrary.org/obo/UBERON_0001003 denotes Skin
T187 26479-26483 http://purl.obolibrary.org/obo/UBERON_0002097 denotes Skin
T188 26479-26483 http://purl.obolibrary.org/obo/UBERON_0002199 denotes Skin
T189 26479-26483 http://www.ebi.ac.uk/efo/EFO_0000962 denotes Skin
T190 26550-26555 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T191 26563-26568 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T192 26563-26568 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T193 26569-26574 http://purl.obolibrary.org/obo/UBERON_0000955 denotes Brain
T194 26569-26574 http://www.ebi.ac.uk/efo/EFO_0000302 denotes Brain
T195 26597-26600 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T196 26597-26600 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T197 26597-26600 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T198 26602-26624 http://purl.obolibrary.org/obo/UBERON_0001017 denotes Central Nervous System
T199 26602-26624 http://www.ebi.ac.uk/efo/EFO_0000302 denotes Central Nervous System
T200 26602-26624 http://www.ebi.ac.uk/efo/EFO_0000908 denotes Central Nervous System
T201 26671-26678 http://purl.obolibrary.org/obo/OBI_0100026 denotes Organic
T202 26671-26678 http://purl.obolibrary.org/obo/UBERON_0000468 denotes Organic
T203 26752-26757 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T204 26835-26837 http://purl.obolibrary.org/obo/CLO_0004265 denotes HT
T205 26859-26863 http://purl.obolibrary.org/obo/UBERON_0000014 denotes Skin
T206 26859-26863 http://purl.obolibrary.org/obo/UBERON_0001003 denotes Skin
T207 26859-26863 http://purl.obolibrary.org/obo/UBERON_0002097 denotes Skin
T208 26859-26863 http://purl.obolibrary.org/obo/UBERON_0002199 denotes Skin
T209 26859-26863 http://www.ebi.ac.uk/efo/EFO_0000962 denotes Skin
T210 27159-27160 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T211 27194-27195 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T212 27234-27236 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T213 27268-27273 http://purl.obolibrary.org/obo/CLO_0002821 denotes D: S1
T214 27268-27273 http://purl.obolibrary.org/obo/CLO_0002822 denotes D: S1
T215 27429-27430 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T216 27481-27492 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2 cell
T217 27515-27519 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T218 27515-27519 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T219 27515-27519 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T220 27515-27519 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T221 27515-27519 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T222 27654-27660 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T223 27829-27834 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T224 27829-27834 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T225 27835-27840 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T226 27835-27840 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T227 27859-27881 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T228 27859-27881 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T229 27859-27881 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T230 27883-27886 http://www.ebi.ac.uk/efo/EFO_0000302 denotes CNS
T231 27883-27886 http://www.ebi.ac.uk/efo/EFO_0000908 denotes CNS
T232 27883-27886 http://purl.obolibrary.org/obo/UBERON_0001017 denotes CNS
T233 27925-27926 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 27987-27994 http://purl.obolibrary.org/obo/OBI_0100026 denotes organic
T235 27987-27994 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organic
T236 28229-28233 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T237 28229-28233 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T238 28229-28233 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T239 28229-28233 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T240 28229-28233 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T241 28301-28307 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T242 28433-28435 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T243 28614-28616 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T244 28724-28727 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T245 28724-28727 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T246 28756-28758 http://purl.obolibrary.org/obo/CLO_0009126 denotes SR
T247 29160-29162 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T248 29223-29225 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T249 29248-29251 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T250 29248-29251 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T251 29921-29923 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T252 29924-29926 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T253 31160-31163 http://purl.obolibrary.org/obo/CLO_0002494 denotes ClC
T254 31284-31287 http://purl.obolibrary.org/obo/CLO_0002494 denotes ClC
T255 31646-31647 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T256 32048-32050 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T257 32062-32063 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T258 32319-32321 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T259 32511-32512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T260 32736-32737 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T261 32938-32940 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T262 32968-32971 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T263 32968-32971 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T264 32980-32981 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T265 32984-32985 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T266 33248-33251 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T267 33248-33251 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T268 33409-33412 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T269 33438-33439 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T270 33617-33620 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T271 33642-33645 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T272 33642-33645 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T273 33642-33645 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T274 33642-33645 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T275 33642-33645 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T276 33642-33645 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T277 33642-33645 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T278 33667-33668 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T279 34001-34004 http://purl.obolibrary.org/obo/CLO_0037067 denotes VAL
T280 34037-34038 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T281 34503-34506 http://purl.obolibrary.org/obo/CLO_0001417 denotes 556
T282 34558-34559 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T283 34604-34607 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T284 34762-34765 http://purl.obolibrary.org/obo/CLO_0001001 denotes 813
T285 34932-34933 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T286 34935-34938 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T287 34935-34938 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T288 34963-34964 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T289 34966-34969 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T290 34966-34969 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T291 35194-35196 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T292 35354-35359 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T293 35404-35410 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T294 35540-35541 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T295 35605-35610 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T296 35612-35618 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis
T297 35630-35637 http://purl.obolibrary.org/obo/UBERON_0003688 denotes omentum
T298 35659-35665 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T299 35659-35665 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T300 35659-35665 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T301 35666-35672 http://purl.obolibrary.org/obo/UBERON_0001851 denotes cortex
T302 35710-35714 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T303 35710-35714 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T304 35763-35769 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis
T305 35781-35788 http://purl.obolibrary.org/obo/UBERON_0003688 denotes omentum
T306 35807-35812 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aorta
T307 35821-35830 http://purl.obolibrary.org/obo/UBERON_0000026 denotes appendage
T308 35821-35830 http://www.ebi.ac.uk/efo/EFO_0000799 denotes appendage
T309 35847-35858 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblasts
T310 35968-35973 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T311 36001-36006 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T312 36109-36114 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T313 36126-36133 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonic
T314 36134-36144 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T315 36145-36150 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T316 36450-36455 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T317 36457-36458 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T318 36636-36637 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T319 36725-36730 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T320 36768-36773 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T321 36815-36820 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T322 36824-36831 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonic
T323 36832-36842 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T324 36843-36848 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T325 37542-37544 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T326 37906-37908 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T327 38053-38054 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 38093-38097 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T329 38635-38638 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T330 38635-38638 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T331 39509-39510 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 39882-39883 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T333 39922-39931 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T334 39997-39998 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T335 40053-40054 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T336 40454-40458 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T337 40454-40458 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T338 40463-40476 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T339 40620-40621 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T340 40657-40662 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T341 40806-40807 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T342 40841-40842 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T343 40954-40957 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T344 40958-40959 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T345 41366-41367 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T346 41434-41435 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T347 41734-41742 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T348 41885-41893 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T349 41955-41956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T350 41973-41976 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T351 42044-42049 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T352 42215-42231 http://purl.obolibrary.org/obo/UBERON_0000949 denotes endocrine system
T353 42215-42231 http://www.ebi.ac.uk/efo/EFO_0002969 denotes endocrine system
T354 42317-42326 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T355 42353-42362 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T356 42372-42373 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T357 42387-42390 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T358 42504-42513 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T359 42698-42711 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T360 42744-42748 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T361 42749-42753 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T362 42754-42763 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T363 42773-42782 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T364 42808-42814 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T365 42808-42814 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T366 42808-42814 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T367 42808-42814 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T368 42878-42892 http://purl.obolibrary.org/obo/UBERON_0001133 denotes cardiac muscle
T369 43018-43019 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T370 43537-43550 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T371 43552-43561 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T372 43592-43593 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T373 43658-43664 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T374 43688-43693 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T375 43688-43693 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T376 43695-43697 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T377 43700-43708 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
T378 43710-43712 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T379 43715-43721 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T380 43715-43721 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T381 43715-43721 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T382 43723-43725 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T383 43739-43745 http://purl.obolibrary.org/obo/UBERON_0001052 denotes rectum
T384 43739-43745 http://purl.obolibrary.org/obo/UBERON_0006866 denotes rectum
T385 43781-43782 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T386 43921-43926 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T387 43928-43934 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis
T388 43936-43943 http://purl.obolibrary.org/obo/UBERON_0001013 denotes adipose
T389 43953-43960 http://purl.obolibrary.org/obo/UBERON_0003688 denotes omentum
T390 43962-43967 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T391 43962-43967 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T392 43962-43967 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T393 43962-43967 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T394 43984-43990 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T395 43984-43990 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T396 43984-43990 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T397 43991-43997 http://purl.obolibrary.org/obo/UBERON_0001851 denotes cortex
T398 44026-44029 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T399 44101-44106 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T400 44196-44197 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T401 44575-44576 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T402 44841-44845 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T403 45139-45141 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T404 45180-45183 http://purl.obolibrary.org/obo/CLO_0007875 denotes MS1
T405 45180-45183 http://purl.obolibrary.org/obo/CLO_0052410 denotes MS1
T406 45460-45461 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T407 45483-45486 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T408 45573-45578 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T409 45590-45592 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T410 45595-45596 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T411 45791-45792 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T412 45894-45902 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T413 45947-45948 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T414 45994-46001 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T415 46013-46018 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T416 46044-46049 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T417 46089-46094 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T418 46285-46292 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T419 46311-46315 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T420 46369-46370 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T421 46516-46521 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T422 46533-46535 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T423 46716-46721 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T424 47474-47475 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T425 47923-47927 http://purl.obolibrary.org/obo/CLO_0001979 denotes bing
T426 48042-48046 http://purl.obolibrary.org/obo/CLO_0001979 denotes Bing
T427 48118-48122 http://purl.obolibrary.org/obo/CLO_0001979 denotes Bing
T428 48757-48761 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T429 48833-48838 http://purl.obolibrary.org/obo/UBERON_0007688 denotes Field

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 756-764 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T2 888-893 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T3 956-963 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T4 1042-1045 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T5 1175-1177 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T6 1275-1283 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T7 1513-1517 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T8 1652-1654 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T10 1667-1669 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T11 1815-1823 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T12 1834-1838 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T13 1980-1984 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T14 2588-2594 Chemical denotes corona http://purl.obolibrary.org/obo/CHEBI_37409
T15 2899-2904 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T16 2958-2966 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T17 3799-3802 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T18 4660-4669 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T19 5165-5173 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T20 5261-5269 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T21 5766-5771 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T22 5867-5870 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T23 5955-5958 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T24 6059-6062 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T25 7150-7154 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T26 7165-7167 Chemical denotes DL http://purl.obolibrary.org/obo/CHEBI_68596
T27 7339-7342 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T28 8101-8104 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T29 8185-8187 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T30 8533-8536 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T32 8628-8631 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T34 8703-8706 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T36 8755-8763 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T37 8813-8816 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T39 8948-8951 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T41 9227-9230 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T43 9337-9340 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T44 10004-10006 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T45 10478-10487 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T46 10494-10496 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T47 10497-10506 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T48 10636-10640 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T49 10891-10899 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T50 11007-11010 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T53 11125-11132 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T54 11148-11155 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55 11157-11160 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T56 11194-11201 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T57 11283-11286 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T60 11500-11508 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T61 12067-12075 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T62 12212-12220 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T63 12259-12263 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T64 12544-12549 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T65 12621-12626 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T66 12711-12716 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T67 12809-12813 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T68 12881-12886 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T69 13445-13449 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T70 13673-13678 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T71 13960-13962 Chemical denotes DL http://purl.obolibrary.org/obo/CHEBI_68596
T72 14166-14169 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T73 14599-14602 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T74 14741-14749 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T75 18262-18267 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T76 18287-18292 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T77 18308-18316 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T78 18631-18637 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T79 18660-18675 Chemical denotes steroid hormone http://purl.obolibrary.org/obo/CHEBI_26764
T80 18660-18667 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T81 18668-18675 Chemical denotes hormone http://purl.obolibrary.org/obo/CHEBI_24621
T82 18714-18722 Chemical denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T85 18727-18734 Chemical denotes proline http://purl.obolibrary.org/obo/CHEBI_17203|http://purl.obolibrary.org/obo/CHEBI_26271
T87 18750-18753 Chemical denotes ABC http://purl.obolibrary.org/obo/CHEBI_421707
T88 18792-18795 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T89 19109-19112 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T90 19165-19177 Chemical denotes beta-Alanine http://purl.obolibrary.org/obo/CHEBI_16958
T91 19165-19169 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T92 19170-19177 Chemical denotes Alanine http://purl.obolibrary.org/obo/CHEBI_16449
T93 19342-19354 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T94 19350-19354 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T95 19614-19617 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T96 19670-19673 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T97 19848-19853 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T98 20018-20020 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T99 20070-20072 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T100 20140-20145 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T101 20198-20200 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T102 20355-20357 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T103 20395-20397 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T104 20499-20501 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T105 20553-20555 Chemical denotes TF http://purl.obolibrary.org/obo/CHEBI_74862
T106 20579-20582 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T108 20686-20689 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T110 20849-20852 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T112 20968-20975 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T113 20999-21002 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T115 21476-21482 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T116 21505-21512 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T118 21710-21713 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T120 21883-21886 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T122 21996-21998 Chemical denotes 5B http://purl.obolibrary.org/obo/CHEBI_27560
T123 22301-22304 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T125 22568-22583 Chemical denotes thyroid hormone http://purl.obolibrary.org/obo/CHEBI_60311
T126 22576-22583 Chemical denotes hormone http://purl.obolibrary.org/obo/CHEBI_24621
T127 22648-22654 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T128 22750-22753 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T130 23159-23166 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T131 23310-23313 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T133 23869-23876 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T135 23896-23900 Chemical denotes cGMP http://purl.obolibrary.org/obo/CHEBI_16356
T136 23936-23942 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T137 24022-24025 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T138 24397-24405 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T139 24468-24476 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T140 24536-24544 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T141 24605-24613 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T142 24678-24686 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T143 24725-24730 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T144 24899-24901 Chemical denotes ID http://purl.obolibrary.org/obo/CHEBI_141439
T145 25023-25026 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T146 25088-25091 Chemical denotes Man http://purl.obolibrary.org/obo/CHEBI_37684
T147 25384-25388 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T148 25540-25542 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T149 25791-25793 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T150 25880-25884 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T151 25996-25998 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T152 26679-26685 Chemical denotes Cation http://purl.obolibrary.org/obo/CHEBI_36916
T153 26767-26769 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T154 26782-26784 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T155 26855-26857 Chemical denotes SS http://purl.obolibrary.org/obo/CHEBI_73653
T156 26879-26881 Chemical denotes MT http://purl.obolibrary.org/obo/CHEBI_73614
T157 27149-27157 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T158 27162-27164 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T160 27171-27178 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T161 27180-27183 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T162 27197-27199 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T164 27257-27260 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T167 27304-27306 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T168 27538-27542 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T169 27987-28001 Chemical denotes organic cation http://purl.obolibrary.org/obo/CHEBI_25697
T170 27995-28001 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T171 28151-28160 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T172 28167-28169 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T173 28170-28179 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T174 28406-28408 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T176 28433-28435 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T177 28469-28479 Chemical denotes Medicarpin http://purl.obolibrary.org/obo/CHEBI_6714
T178 28491-28501 Chemical denotes Cianidanol http://purl.obolibrary.org/obo/CHEBI_15600
T179 28561-28563 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T180 28617-28626 Chemical denotes letrozole http://purl.obolibrary.org/obo/CHEBI_6413
T181 28703-28713 Chemical denotes naringenin http://purl.obolibrary.org/obo/CHEBI_50202
T182 28728-28741 Chemical denotes Leucocyanidol http://purl.obolibrary.org/obo/CHEBI_11412|http://purl.obolibrary.org/obo/CHEBI_15758
T184 28826-28829 Chemical denotes Tyr http://purl.obolibrary.org/obo/CHEBI_17895|http://purl.obolibrary.org/obo/CHEBI_18186|http://purl.obolibrary.org/obo/CHEBI_46858
T187 28832-28835 Chemical denotes Phe http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997
T189 28852-28866 Chemical denotes Liquiritigenin http://purl.obolibrary.org/obo/CHEBI_28777
T190 28885-28894 Chemical denotes taxifolin http://purl.obolibrary.org/obo/CHEBI_38747
T191 28947-28956 Chemical denotes flavanone http://purl.obolibrary.org/obo/CHEBI_5070
T192 29023-29034 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T193 29219-29221 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T195 29223-29225 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T196 29244-29246 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T197 29295-29303 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T198 29383-29386 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T201 29501-29508 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T202 29521-29528 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T203 29530-29533 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T204 29896-29904 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T205 29915-29917 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T207 29924-29926 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T208 29946-29948 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T209 30240-30243 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T212 30663-30670 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T213 30733-30740 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T214 30741-30744 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T215 31386-31390 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T216 31562-31566 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T217 31632-31634 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T219 31717-31724 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T220 31726-31729 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T221 31749-31751 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T222 31759-31761 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T223 31813-31816 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T225 31860-31862 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T227 31951-31956 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T229 31957-31962 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T231 31964-31966 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T232 32010-32013 Chemical denotes ASN http://purl.obolibrary.org/obo/CHEBI_22653
T233 32147-32150 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T236 32203-32208 Chemical denotes Amide http://purl.obolibrary.org/obo/CHEBI_32988
T237 32209-32211 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T238 32224-32226 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T239 32260-32263 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T241 32378-32380 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T242 32381-32386 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T243 32388-32390 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T244 32391-32393 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T245 32403-32405 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T246 32406-32408 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T247 32422-32424 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T248 32615-32617 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T249 32618-32623 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T251 32624-32632 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T252 32642-32644 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T253 32722-32724 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T254 32843-32849 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T255 32850-32858 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T256 32865-32867 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T257 32868-32873 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T258 32875-32877 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T259 32878-32884 Chemical denotes sulfur http://purl.obolibrary.org/obo/CHEBI_26833
T260 32889-32891 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T261 33056-33063 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T262 33104-33106 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T263 33107-33112 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T265 33113-33121 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T266 33128-33130 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T267 33138-33140 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T268 33141-33143 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T269 33156-33158 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T270 33209-33212 Chemical denotes ALA http://purl.obolibrary.org/obo/CHEBI_16449|http://purl.obolibrary.org/obo/CHEBI_27432
T272 33339-33341 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T273 33342-33344 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T274 33388-33391 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T275 33572-33574 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T276 33626-33629 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T277 33760-33762 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T278 33763-33765 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T279 33778-33780 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T280 33814-33817 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T281 33947-33949 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T282 33983-33986 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T283 33992-33995 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T284 34032-34034 Chemical denotes 9F http://purl.obolibrary.org/obo/CHEBI_24061
T285 34157-34163 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T286 34164-34172 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T287 34179-34181 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T288 34182-34184 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T289 34195-34197 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T290 34208-34210 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T291 34211-34216 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T292 34244-34247 Chemical denotes PHE http://purl.obolibrary.org/obo/CHEBI_28044
T293 34402-34408 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T294 34409-34417 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T295 34436-34441 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T297 34442-34447 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T299 34449-34451 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T300 34452-34458 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T301 34463-34465 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T302 34466-34471 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T303 34679-34681 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T304 34682-34687 Chemical denotes Donor http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891
T306 34688-34696 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T307 34703-34705 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T308 34706-34708 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T309 34722-34724 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T310 34776-34779 Chemical denotes LYS http://purl.obolibrary.org/obo/CHEBI_25094
T311 34922-34930 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T312 34945-34952 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T313 35194-35196 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T314 36042-36050 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T315 36077-36085 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T316 36559-36563 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T317 36653-36661 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T318 36935-36943 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T319 36953-36958 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T320 37114-37122 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T321 37294-37298 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T322 38019-38023 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T323 38146-38150 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T324 38616-38624 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T325 38919-38922 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T328 39286-39293 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T329 39346-39353 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T330 39354-39357 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T331 39659-39663 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T332 39737-39741 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T333 40132-40139 Chemical denotes diamond http://purl.obolibrary.org/obo/CHEBI_33417
T334 40723-40728 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T335 40824-40828 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T336 40940-40948 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T337 40950-40953 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T338 41744-41749 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T339 41769-41774 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T340 41790-41798 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T341 41988-41993 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T342 42115-42124 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T343 42180-42185 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T344 42215-42224 Chemical denotes endocrine http://purl.obolibrary.org/obo/CHEBI_24621
T345 42765-42772 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T347 43051-43054 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T348 43095-43098 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T349 43400-43404 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T350 44228-44231 Chemical denotes TTD http://purl.obolibrary.org/obo/CHEBI_73659
T351 44577-44581 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T352 44621-44625 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T353 44756-44758 Chemical denotes MW http://purl.obolibrary.org/obo/CHEBI_74709
T354 44827-44831 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T355 45135-45137 Chemical denotes M3 http://purl.obolibrary.org/obo/CHEBI_51083|http://purl.obolibrary.org/obo/CHEBI_53453
T357 45150-45152 Chemical denotes O2 http://purl.obolibrary.org/obo/CHEBI_15379
T358 45330-45338 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T359 46341-46343 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T360 46420-46431 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T361 48673-48679 Chemical denotes Action http://purl.obolibrary.org/obo/CHEBI_5133

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1087-1093 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T2 1095-1132 Phenotype denotes chronic obstructive pulmonary Disease http://purl.obolibrary.org/obo/HP_0006510
T3 1242-1251 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 3005-3014 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 4157-4162 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T6 4478-4484 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T7 4500-4511 Phenotype denotes tonsillitis http://purl.obolibrary.org/obo/HP_0011110
T8 4516-4527 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T9 6551-6560 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T10 11896-11905 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T11 18904-18908 Phenotype denotes acne http://purl.obolibrary.org/obo/HP_0001061
T12 18928-18955 Phenotype denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/HP_0008711
T13 18957-18981 Phenotype denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/HP_0001406
T14 19314-19326 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T15 23159-23177 Phenotype denotes insulin resistance http://purl.obolibrary.org/obo/HP_0000855
T16 35914-35923 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 36021-36030 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T18 36338-36347 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T19 36695-36704 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T20 39864-39870 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T21 39885-39911 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T22 40485-40501 Phenotype denotes Severe infection http://purl.obolibrary.org/obo/HP_0032169
T23 40520-40540 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T24 41080-41085 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T25 41193-41202 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T26 44074-44083 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T27 44378-44384 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T28 44386-44412 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T29 44414-44451 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T30 44453-44477 Phenotype denotes intrahepatic cholestasis http://purl.obolibrary.org/obo/HP_0001406
T31 44487-44494 Phenotype denotes ileitis http://purl.obolibrary.org/obo/HP_0032564

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 878-911 http://purl.obolibrary.org/obo/GO_0045834 denotes activity, lipid metabolic process
T2 888-911 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolic process
T3 894-911 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolic process
T4 913-932 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostatic process
T5 956-976 http://purl.obolibrary.org/obo/GO_0006694 denotes steroid biosynthesis
T6 964-976 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T7 978-1000 http://purl.obolibrary.org/obo/GO_0035357 denotes PPAR signaling pathway
T8 983-1000 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T9 983-992 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T10 1002-1033 http://purl.obolibrary.org/obo/GO_0033211 denotes adipocytokine signaling pathway
T11 1002-1033 http://purl.obolibrary.org/obo/GO_0033210 denotes adipocytokine signaling pathway
T12 1002-1033 http://purl.obolibrary.org/obo/GO_0033209 denotes adipocytokine signaling pathway
T13 1016-1033 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T14 1016-1025 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T15 1175-1177 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T16 2072-2094 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling transduction
T17 2072-2081 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T18 2082-2094 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T19 2305-2315 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T20 4486-4498 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T21 4901-4910 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T22 4924-4953 http://purl.obolibrary.org/obo/GO_0050728 denotes inhibit inflammatory response
T23 4932-4953 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T24 8161-8183 http://purl.obolibrary.org/obo/GO_0000981 denotes transcriptional factor
T25 8185-8187 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T26 9087-9104 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T27 9087-9096 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T28 10365-10374 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T29 11157-11168 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T30 18252-18285 http://purl.obolibrary.org/obo/GO_0045834 denotes activity, lipid metabolic process
T31 18262-18285 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolic process
T32 18268-18285 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolic process
T33 18302-18334 http://purl.obolibrary.org/obo/GO_0044281 denotes small molecule metabolic process
T34 18317-18334 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolic process
T35 18336-18355 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostatic process
T36 18375-18406 http://purl.obolibrary.org/obo/GO_0008284 denotes activity and cell proliferation
T37 18388-18406 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T38 18572-18584 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T39 18586-18617 http://purl.obolibrary.org/obo/GO_0033211 denotes adipocytokine signaling pathway
T40 18586-18617 http://purl.obolibrary.org/obo/GO_0033210 denotes adipocytokine signaling pathway
T41 18586-18617 http://purl.obolibrary.org/obo/GO_0033209 denotes adipocytokine signaling pathway
T42 18600-18617 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T43 18600-18609 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T44 18668-18688 http://purl.obolibrary.org/obo/GO_0042446 denotes hormone biosynthesis
T45 18676-18688 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T46 18690-18712 http://purl.obolibrary.org/obo/GO_0035357 denotes PPAR signaling pathway
T47 18695-18712 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T48 18695-18704 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T49 18727-18745 http://purl.obolibrary.org/obo/GO_0006560 denotes proline metabolism
T50 18735-18745 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T51 18750-18766 http://purl.obolibrary.org/obo/GO_0140359 denotes ABC transporters
T52 19133-19160 http://purl.obolibrary.org/obo/GO_0050877 denotes neurological system process
T53 19146-19160 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T54 19165-19188 http://purl.obolibrary.org/obo/GO_0019482 denotes beta-Alanine metabolism
T55 19178-19188 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T56 19219-19240 http://purl.obolibrary.org/obo/GO_0061024 denotes membrane organization
T57 19293-19309 http://purl.obolibrary.org/obo/GO_0007623 denotes circadian rhythm
T58 19303-19309 http://purl.obolibrary.org/obo/GO_0048511 denotes rhythm
T59 19342-19392 http://purl.obolibrary.org/obo/GO_0003700 denotes nucleic acid binding transcription factor activity
T60 19363-19383 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T61 19363-19376 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T62 19402-19417 http://purl.obolibrary.org/obo/GO_0006694 denotes steroidogenesis
T63 19471-19480 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T64 20018-20020 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T65 20070-20072 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T66 20198-20200 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T67 20355-20357 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T68 20395-20397 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T69 20499-20501 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T70 20553-20555 http://purl.obolibrary.org/obo/GO_0000981 denotes TF
T71 21505-21522 http://purl.obolibrary.org/obo/GO_0019722 denotes calcium signaling
T72 21513-21522 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T73 21554-21564 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T74 22176-22186 http://purl.obolibrary.org/obo/GO_0006096 denotes glycolysis
T75 22189-22204 http://purl.obolibrary.org/obo/GO_0006094 denotes gluconeogenesis
T76 22206-22229 http://purl.obolibrary.org/obo/GO_0007219 denotes Notch signaling pathway
T77 22212-22229 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T78 22212-22221 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T79 22584-22601 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T80 22584-22593 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T81 22603-22634 http://purl.obolibrary.org/obo/GO_0033211 denotes adipocytokine signaling pathway
T82 22603-22634 http://purl.obolibrary.org/obo/GO_0033210 denotes adipocytokine signaling pathway
T83 22603-22634 http://purl.obolibrary.org/obo/GO_0033209 denotes adipocytokine signaling pathway
T84 22617-22634 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T85 22617-22626 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T86 23179-23210 http://purl.obolibrary.org/obo/GO_0033211 denotes adipocytokine signaling pathway
T87 23179-23210 http://purl.obolibrary.org/obo/GO_0033210 denotes adipocytokine signaling pathway
T88 23179-23210 http://purl.obolibrary.org/obo/GO_0033209 denotes adipocytokine signaling pathway
T89 23193-23210 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T90 23193-23202 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T91 23217-23237 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T92 23869-23886 http://purl.obolibrary.org/obo/GO_0019722 denotes calcium signaling
T93 23877-23886 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T94 23905-23922 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T95 23905-23914 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T96 26442-26463 http://purl.obolibrary.org/obo/GO_0050892 denotes Intestinal Absorption
T97 26671-26697 http://purl.obolibrary.org/obo/GO_0015695 denotes Organic Cation Transporter
T98 27180-27191 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T99 27987-28013 http://purl.obolibrary.org/obo/GO_0015695 denotes organic cation transporter
T100 29530-29541 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T101 30741-30752 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T102 31726-31737 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T103 39354-39365 http://purl.obolibrary.org/obo/GO_0022831 denotes ion channel
T104 39922-39931 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T105 41734-41767 http://purl.obolibrary.org/obo/GO_0045834 denotes activity, lipid metabolic process
T106 41744-41767 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolic process
T107 41750-41767 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolic process
T108 41784-41816 http://purl.obolibrary.org/obo/GO_0044281 denotes small molecule metabolic process
T109 41799-41816 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolic process
T110 41822-41841 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostatic process
T111 41988-42003 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolic
T112 42180-42196 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolism
T113 42186-42196 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T114 42312-42334 http://purl.obolibrary.org/obo/GO_0035357 denotes PPAR signaling pathway
T115 42317-42334 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T116 42317-42326 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T117 42339-42370 http://purl.obolibrary.org/obo/GO_0033211 denotes adipocytokine signaling pathway
T118 42339-42370 http://purl.obolibrary.org/obo/GO_0033210 denotes adipocytokine signaling pathway
T119 42339-42370 http://purl.obolibrary.org/obo/GO_0033209 denotes adipocytokine signaling pathway
T120 42353-42370 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T121 42353-42362 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T122 42499-42521 http://purl.obolibrary.org/obo/GO_0035357 denotes PPAR signaling pathway
T123 42504-42521 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T124 42504-42513 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T125 42557-42568 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T126 42572-42582 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T127 42698-42719 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T128 42705-42719 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T129 42744-42763 http://purl.obolibrary.org/obo/GO_0007267 denotes cell-cell signaling
T130 42754-42763 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T131 42765-42782 http://purl.obolibrary.org/obo/GO_0019722 denotes calcium signaling
T132 42773-42782 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T133 42792-42826 http://purl.obolibrary.org/obo/GO_0014829 denotes vascular smooth muscle contraction
T134 42801-42826 http://purl.obolibrary.org/obo/GO_0006939 denotes smooth muscle contraction
T135 42808-42826 http://purl.obolibrary.org/obo/GO_0006936 denotes muscle contraction
T136 42850-42860 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T137 42878-42904 http://purl.obolibrary.org/obo/GO_0060048 denotes cardiac muscle contraction
T138 42886-42904 http://purl.obolibrary.org/obo/GO_0006936 denotes muscle contraction
T139 43516-43535 http://purl.obolibrary.org/obo/GO_0034097 denotes responses, cytokine
T140 43552-43574 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling transduction
T141 43552-43561 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T142 43562-43574 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T143 45559-45569 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T144 46311-46321 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T145 46344-46357 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T146 46420-46443 http://purl.obolibrary.org/obo/GO_0042632 denotes cholesterol homeostasis
T147 46432-46443 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T148 46451-46463 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-130 Sentence denotes Protection against COVID-19 injury by qingfei paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming
T2 132-150 Sentence denotes Graphical abstract
T3 152-162 Sentence denotes Highlights
T4 163-205 Sentence denotes • A novel FUNP analysis on QFPD function.
T5 206-290 Sentence denotes • QFPD act on COVID-19 via anti-viral, anti-inflammatory and metabolic programming.
T6 291-366 Sentence denotes • 9 QFPD ingredients presented good molecular docking score for 2019-nCov.
T7 367-437 Sentence denotes • SGMH, MXSG and Others are the top 3 efficient formula for COVID-19.
T8 439-447 Sentence denotes Abstract
T9 448-562 Sentence denotes Qingfei Paidu decoction (QFPD), a multi-component herbal formula, has been widely used to treat COVID-19 in China.
T10 563-636 Sentence denotes However, its active compounds and mechanisms of action are still unknown.
T11 637-765 Sentence denotes Firstly, we divided QFPD into five functional units (FUs) according to the compatibility theory of traditional Chinese medicine.
T12 766-1184 Sentence denotes The corresponding common targets of the five FUs were all significantly enriched in Go Ontology (oxidoreductase activity, lipid metabolic process, homeostatic process, etc.), KEGG pathways (steroid biosynthesis, PPAR signaling pathway, adipocytokine signaling pathway, etc.), TTD diseases (chronic inflammatory diseases, asthma, chronic obstructive pulmonary Disease, etc.), miRNA (MIR183), kinase (CDK7) and TF (LXR).
T13 1185-1284 Sentence denotes QFPD contained 257 specific targets in addition to HCoV, pneumonia and ACE2 co-expression proteins.
T14 1285-1402 Sentence denotes Then, network topology analysis of the five components-target-pathway-disease networks yielded 67 active ingredients.
T15 1403-1617 Sentence denotes In addition, ADMET estimations showed that 20 compounds passed the stringent lead-like criteria and in silico drug-likeness test with high gastrointestinal absorption and the median lethal dose (LD50 > 1600 mg/kg).
T16 1618-1824 Sentence denotes Moreover, 4 specific ingredients (M3, S1, X2 and O2) and 5 common ingredients (MS1, MX16, SX1, WO1 and XO1) of QFPD presented good molecular docking score for 2019-nCov structure and non-structure proteins.
T17 1825-2100 Sentence denotes Finally, drug perturbation of COVID-19 network robustness showed that all five FUs may protect COVID-19 independently, and target 8 specifically expressed drug-attacked nodes which were related to the bacterial and viral responses, immune system, signaling transduction, etc.
T18 2101-2258 Sentence denotes In conclusion, our new FUNP analysis showed that QFPD had a protection effect on COVID-19 by regulating a complex molecular network with safety and efficacy.
T19 2259-2384 Sentence denotes Part of the mechanism was associated with the regulation of anti-viral, anti-inflammatory activity and metabolic programming.
T20 2386-2401 Sentence denotes 1 Introduction
T21 2402-2515 Sentence denotes 2019-novel coronavirus (2019-nCov) outbreak took place in December 2019 and continues to spread around the world.
T22 2516-2629 Sentence denotes By April 3, 2020, more than 1 million patients have been diagnosed with corona virus disease 2019 (COVID-19) [1].
T23 2630-2845 Sentence denotes The virus has a long incubation period, is highly contagious, and is generally susceptible to all types of people, which has a huge negative impact on people's health, economic development, and social stability [2].
T24 2846-2937 Sentence denotes However, there is still a lack of effective clinical drugs or vaccine to control the virus.
T25 2938-3071 Sentence denotes Traditional Chinese medicine has a good effect on viral infectious pneumonia and has shown a certain effect in the treatment of SARS.
T26 3072-3763 Sentence denotes On February 7, 2020, the China Health Commission and the Administration of Traditional Chinese Medicine jointly issued a notice recommending formula Qingfei Paidu decoction (QFPD, Herba Ephedrae, Radix Glycyrrhizae, Semen Armeniacae Amarum, Gypsum Fibrosum, Ramulus Cinnamomi, Rhizoma Alismatis, Polyporus Umbellatus, Rhizoma Atractylodis Macrocephalae, Poria, Radix Bupleuri, Radix Scutellariae, Rhizome Pinelliae Preparata, Rhizoma Zingiberis Recens, Radix Asteris, Flos Farfarae, Rhizoma Belamcandae, Herba Asari, Rhizoma Dioscoreae, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Herba Pogostemonis) for the treatment of COVID-19 according to clinical treatment and efficacy.
T27 3764-4020 Sentence denotes QFPD is a compound prescription in TCM including Ma Xing Shi Gan decoction (MSXG), She Gan Ma Huang decoction (SGMH), Xiao Chai Hu (XCH), and Wu Ling San (WLS), which was first discovered in the classic Treatise on Exogenous Febrile Disease (Shanghan Lun).
T28 4021-4267 Sentence denotes MXSG (Herba Ephedrae, Radix Glycyrrhizae, Semen Armeniacae Amarum, Gypsum Fibrosum) has been used for the treatment of the common cold, fever, and influenza virus infections via damaging the viral surface structure and inhibiting viral entry [3].
T29 4268-4532 Sentence denotes SGMH (Herba Ephedrae, Rhizome Pinelliae Preparata, Rhizoma Zingiberis Recens, Radix Asteris, Flos Farfarae, Rhizoma Belamcandae, Herba Asari) is a classical prescription for the treatment of flu-like symptoms, asthma, inflammation, tonsillitis and sore throat [4].
T30 4533-4718 Sentence denotes XCH (Radix Glycyrrhizae, Radix Bupleuri, Radix Scutellariae, Rhizome Pinelliae Preparata, Rhizoma Zingiberis Recens) possesses antiviral [5] and various anticarcinogenic properties [6].
T31 4719-4958 Sentence denotes WLS (Ramulus Cinnamomi, Rhizoma Alismatis, Polyporus Umbellatus, Rhizoma Atractylodis Macrocephalae, Poria), a famous Chinese prescription for nephritic syndrome, can improve kidney excretion function and inhibit inflammatory response [7].
T32 4959-5054 Sentence denotes These researches indicate that MXSG, SGMH, XCH and WLS may be functional units of formula QFPD.
T33 5055-5174 Sentence denotes Previous studies have focused on the mechanism of compound prescription based on a single traditional Chinese medicine.
T34 5175-5270 Sentence denotes However, it may not reflect functional compatibility mechanism of traditional Chinese medicine.
T35 5271-5448 Sentence denotes Therefore, it is worthy of comparing the similarities and differences of different QFPD functional units in the treatment of COVID-19, including MXSG, SGMH, XCH, WLS and Others.
T36 5449-5683 Sentence denotes QFPD contains a total of 21 traditional Chinese medicines, and it is difficult to elucidate the complex mechanism of QFPD on COVID-19 by traditional pharmacological methods due to the multi-components and multi-targets of the formula.
T37 5684-5841 Sentence denotes Network pharmacology, a new method in recent years, can integrate interactions of drugs, targets, pathways and diseases into a biological network system [8].
T38 5842-6113 Sentence denotes Therefore, more and more TCM researchers have begun to use network pharmacology to explore the material basis of TCM, and to reveal the overall comprehensive effects of multi-path, multi-component and multi-target of TCM prescription and its treatment of diseases [9,10].
T39 6114-6283 Sentence denotes More importantly, previous study reported that disease conditions can be more fragile than health systems against various perturbations for the un-optimized system [11].
T40 6284-6439 Sentence denotes So the formula may be more effective for COVID-19 disease via the stronger effects on the reduction of the robustness of the COVID-19 disease network [12].
T41 6440-6660 Sentence denotes In our study, since MSXG, SGMH, XCH and WLS have been independently used for the treatment of viral infectious pneumonia, this study firstly screened out major effective compounds from five functional units respectively.
T42 6661-6979 Sentence denotes Then we offered a new understanding of the functional units mechanism of QFPD against COVID-19 by a novel functional units of network pharmacology (FUNP) approach and formula perturbation analysis, and provided a combination strategy to explore mechanisms of inter-ingredients interactions from a holistic perspective.
T43 6981-7005 Sentence denotes 2 Materials and methods
T44 7007-7028 Sentence denotes 2.1 Data preparation
T45 7029-7221 Sentence denotes Compounds of the main herb in formula MSXG, SGMH, XCH, WLS and Others were searched in TCMSP [13], and screened based on drug-likeness (DL) ≥0.18 [14] and oral bioavailability (OB) ≥30 % [15].
T46 7222-7322 Sentence denotes Then, the corresponding Pubchem CIDs of the compounds were retrieved from the Pubchem database [16].
T47 7323-7518 Sentence denotes Finally, BATMAN-TCM [17], an bioinformatics analysis tool for studying TCM’s molecular mechanisms, was used to identify potential target genes of the active components (uploaded by Pubchem CIDs).
T48 7519-7599 Sentence denotes To make the results more credible, we set the cutoff score ≥ 30 as the standard.
T49 7600-7790 Sentence denotes Finally, to discovery the co-differentially presented targets in the five formulae, we conducted pan-formula analysis using Venn diagrams (http://bioinformatics.psb.ugent.be/webtools/Venn/).
T50 7792-7855 Sentence denotes 2.2 Functional and pathway enrichment analyses of QFPD targets
T51 7856-8133 Sentence denotes To better understand the functional involvements of MSXG, SGMH, XCH, WLS and Others targets, bioinformatics analyses of multiple formulae targets were first performed, including Gene Ontology (GO) function term, KEGG biological pathway and OMIM/TTD disease enrichment analyses.
T52 8134-8432 Sentence denotes Then, kinase, microRNA and transcriptional factor (TF) enrichment analyses of the five formulae targets were conducted using the tool WebGestalt (http://bioinfo.vanderbilt.edu/webgestalt) [18] and the bubble and chord plot map were drawn with the R language ggplot2 and GOplot installation package.
T53 8433-8510 Sentence denotes P-values were adjusted for multiple testing by Benjamini-Hochberg adjustment.
T54 8512-8571 Sentence denotes 2.3 Construction of PPI network and MCODE modules analysis
T55 8572-8715 Sentence denotes To further explore the pharmacological mechanisms, five PPI networks were built including: MSXG, SGMH, XCH, WLS and Others targets PPI network.
T56 8716-8870 Sentence denotes Specifically, the five kinds of target proteins were respectively uploaded to Metascape to build PPI networks, with the species limited to “Homo sapiens”.
T57 8871-9030 Sentence denotes Next, MCODE analysis [19], a method for finding densely connected modules in PPI networks, was carried out by Cytoscape 3.2.1 (http://www.cytoscape.org/) [20].
T58 9031-9254 Sentence denotes Finally, KEGG (Kyoto Encyclopedia of Genes and Genomes) signaling pathway enrichment analysis was further conducted on the identified functional modules of MSXG, SGMH, XCH, WLS and Others targets PPI networks, respectively.
T59 9256-9281 Sentence denotes 2.4 Network construction
T60 9282-9445 Sentence denotes Based on the five formulae’s active components, BATMAN-TCM was used to set up five networks of components-target-pathway-disease (MSXG, SGMH, XCH, WLS and Others).
T61 9446-9686 Sentence denotes To emphasize the important elements of the five networks, we only exhibited the hub targets according to the default criteria (targets with no fewer than 6, 5, 8, 7 and 4 linking compounds for MSXG, SGMH, XCH, WLS and Others, respectively).
T62 9687-9809 Sentence denotes Finally, these important linking compounds of MSXG, SGMH, XCH, WLS and Others networks were obtained for further analysis.
T63 9811-9866 Sentence denotes 2.5 ADMET evaluation of the predicted active compounds
T64 9867-10100 Sentence denotes Based on the SwissADME database [21], the physicochemical properties of the active components was predicted, including molecular weight (MW), rotatable bonds count, H-bond acceptors and donors count, TPSA and leadlikeness violations.
T65 10101-10597 Sentence denotes Second, pharmacokinetic properties was predicted through pkCSM database [22], which contained the absorption (Caco-2 cell permeability, HIA and skin permeability), distribution (VDss, unbound fraction, blood-brain barrier and central nervous system permeability), excretion (total clearance and renal OCT2 substrate) and toxicity (AMES toxicity, maximum tolerated dose, hERG I inhibitor, hERG II inhibitor, oral rat acute toxicity (LD50), hepatotoxicity, skin sensitisation, and minnow toxicity).
T66 10599-10621 Sentence denotes 2.6 Molecular docking
T67 10622-10838 Sentence denotes To facilitate drug discovery against COVID-19, we used COVID-19 Docking Server (https://ncov.schanglab.org.cn/index.php) [23] to predict the binding modes between 12 COVID-19 targets and the 20 lead-likeness of QFPD.
T68 10839-11383 Sentence denotes Specifically, the 10 nonstructural and 2 structural proteins of 2019-nCov were collected (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site and E protein [ion channel]); and the corresponding Protein Data Bank (PDB)codes were 6LU7, 4OW0, 3H5Y (with RNA), 3H5Y (without RNA), 6JYT (ADP site), 6JYT (NCB site), 5C8S (ExoN),5C8S (N7-MTase), 2RHB, 2XYR, 4KYJ, and 5 × 29, respectively.
T69 11384-11509 Sentence denotes Finally, Discovery Studio software elucidated the 14 best docking results between compounds and the COVID-19 target proteins.
T70 11511-11580 Sentence denotes 2.7 ACE2 and CD147 expression across tissues and co-expression genes
T71 11581-11732 Sentence denotes To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24].
T72 11733-11827 Sentence denotes And the top 200 co-expression genes of ACE2 and CD147 (P < 1E-16) were obtained, respectively.
T73 11828-11967 Sentence denotes Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/).
T74 11968-12111 Sentence denotes In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained.
T75 12112-12238 Sentence denotes Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets.
T76 12240-12339 Sentence denotes 2.8 Validation of drug positioning for QFPD against COVID-19 via the robustness of disease network
T77 12340-12581 Sentence denotes Since QFPD effects on COVID-19 via multi-component and multi-target, we evaluate the potential efficacy of QFPD through TCMATCOV platform, which uses the quantitative evaluation algorithm of multi-target drugs to disturb the disease network.
T78 12582-12686 Sentence denotes Specifically, the disturbing effect of drugs on diseases is simulated by deleting disease network nodes.
T79 12687-12899 Sentence denotes The disturbance rate of drugs is calculated by comparing the changes of network topology characteristics before and after drug intervention, which is used to evaluate the intervention effect of drugs on diseases.
T80 12900-13069 Sentence denotes Firstly, COVID-19 disease network was constructed based on specific cytokines of COVID-19 [27] and differentially expressed genes of SARS (GSE36969, GSE51387, GSE68820).
T81 13070-13312 Sentence denotes Then, this platform uses four kinds of network topology characteristics to evaluate the robustness of COVID-19 network, including network average connectivity, network average shortest path, connectivity centrality and compactness centrality.
T82 13313-13463 Sentence denotes And the five formulae (MSXG, SGMH, XCH, WLS and Others) disturbance scores are calculated according to the changes before and after drug intervention.
T83 13464-13719 Sentence denotes Finally, the disturbance effect of the five formulae on the COVID-19 network was compared with null models with the total score of the disturbance, and the higher the value is, the higher the damage degree of drugs to the stability of the network is [12].
T84 13720-13867 Sentence denotes We take Banxia tianma baizhu decoction (BXTM) as negative control; and another efficient formula Yi du bi fei decoction (YDBF) as positive control.
T85 13869-13878 Sentence denotes 3 Result
T86 13880-13946 Sentence denotes 3.1 Prediction of active components and potential targets of QFPD
T87 13947-14084 Sentence denotes Firstly, the DL ≥ 0.18 and OB ≥ 30 %.s were set as the standard to screen the chemical components obtained through online database TCMSP.
T88 14085-14304 Sentence denotes Specifically, a total of 175 effective components of QFPD were screened from the TCM database, including 82 species of MSXG, 35 species of SGMH, 105 species of XCH, 21 species of WLS and 32 species of Others (Table 1 ).
T89 14305-14527 Sentence denotes Among these effective components, 89 (50.86 %) components exited in more than two formulae; CID5280343 and CID5280794 were owned by MXSG, Others, SGMH and XCH; CID12303645 was owned by MXSG, Others, WLS and XCH (Fig. 1 A).
T90 14528-14728 Sentence denotes Secondly, a total of 300 targets of QFPD were screened from the BATMAN-TCM database, including 192 targets of MSXG, 201 targets of SGMH, 221 targets of XCH, 96 targets of WLS and 99 targets of Others.
T91 14729-14801 Sentence denotes Among these proteins, 21 (7%) targets exited in five formulae (Fig. 1B).
T92 14802-14839 Sentence denotes Table 1 Effective components of QFPD.
T93 14840-14861 Sentence denotes Formula N PubChem_Cid
T94 14862-15757 Sentence denotes MSXG 82 CID10090416,CID10542808,CID10881804,CID11267805,CID114829,CID11558452,CID11602329,CID11975273,CID120074,CID12303645,CID124049,CID124052,CID13965473,CID14604077,CID14604078,CID14604081,CID15228663,CID15380912,CID162412,CID177149,CID193679,CID197678,CID23724664,CID25015742,CID268208,CID336327,CID354368,CID3764,CID439246,CID440833,CID442411,CID44257530,CID480774,CID480780,CID480787,CID480859,CID480873,CID49856081,CID503731,CID503737,CID5280343,CID5280378,CID5280448,CID5280544,CID5280794,CID5280863,CID5281619,CID5281654,CID5281789,CID5282768,CID5282805,CID5312521,CID5316900,CID5317300,CID5317478,CID5317479,CID5317480,CID5317652,CID5317768,CID5317777,CID5318437,CID5318585,CID5318679,CID5318869,CID5318998,CID5318999,CID5319013,CID5320083,CID5460988,CID5481234,CID5481948,CID5481949,CID5997,CID636883,CID637112,CID64971,CID6918970,CID73205,CID928837,CID9927807,CID15840593,CID15228662
T95 15758-16244 Sentence denotes SGMH 35 CID1135,CID1174,CID3026,CID5789,CID6782,CID6998,CID8437,CID8679,CID13625,CID117158,CID159225,CID185,CID10019512,CID11438306,CID11869417,CID11870462,CID12315507,CID162350,CID16726037,CID222284,CID389888,CID3902,CID440833,CID5280343,CID5280445,CID5280544,CID5280794,CID5280863,CID5281331,CID5281605,CID5281616,CID5281628,CID5281654,CID5281779,CID5282768,CID5315890,CID5316876,CID5320945,CID5484202,CID5488781,CID5491637,CID64959,CID64982,CID676152,CID71307581,CID72307,CID13688752
T96 16245-17385 Sentence denotes XCH 105 CID10090416,CID10542808,CID10881804,CID11267805,CID11438306,CID114829,CID11558452,CID11602329,CID117443,CID12303645,CID124049,CID124052,CID124211,CID13965473,CID14135323,CID14604077,CID14604078,CID14604081,CID15228662,CID15228663,CID15380912,CID156992,CID158311,CID15840593,CID159029,CID161271,CID162412,CID177149,CID185034,CID193679,CID197678,CID222284,CID23724664,CID25015742,CID25721350,CID268208,CID336327,CID354368,CID373261,CID3764,CID389001,CID389888,CID439246,CID442411,CID44257530,CID44258628,CID480774,CID480780,CID480787,CID480859,CID480873,CID49856081,CID503731,CID503737,CID5280343,CID5280378,CID5280442,CID5280448,CID5280794,CID5280863,CID5281605,CID5281619,CID5281654,CID5281674,CID5281703,CID5281789,CID5282768,CID5312521,CID5316900,CID5317300,CID5317478,CID5317479,CID5317480,CID5317652,CID5317768,CID5317777,CID5318437,CID5318585,CID5318679,CID5318869,CID5318998,CID5318999,CID5319013,CID5319042,CID5319252,CID5320083,CID5320315,CID5320399,CID5321865,CID5322059,CID5322078,CID5460988,CID5481234,CID5481948,CID5481949,CID5484202,CID636883,CID637112,CID64959,CID64971,CID64982,CID73205,CID821279,CID928837,CID9927807
T97 17386-17626 Sentence denotes WLS 21 CID10181133,CID10743008,CID12303645,CID14036811,CID15225964,CID15226717,CID15976101,CID182232,CID222284,CID44575602,CID5283628,CID5471851,CID5471852,CID56668247,CID6436630,CID712316,CID73402,CID9064,CID9805290,CID14448075,CID14236575
T98 17627-17971 Sentence denotes Others 32 CID10212,CID11824478,CID122159,CID12303645,CID14057197,CID145659,CID17897,CID33934,CID373261,CID40429858,CID42607889,CID439246,CID442834,CID443024,CID5280343,CID5280445,CID5280794,CID5281326,CID5281617,CID5281781,CID5319406,CID5320621,CID5495928,CID5997,CID631170,CID632135,CID676152,CID712316,CID72344,CID79730,CID1149877,CID45359875
T99 17972-18043 Sentence denotes Fig. 1 Venn diagram of the five formulae’ active compounds and targets.
T100 18044-18069 Sentence denotes A: compounds, B: targets.
T101 18071-18134 Sentence denotes 3.2 Functional and pathway enrichment analyses of QFPD targets
T102 18135-18407 Sentence denotes As shown in Fig. 2 , the 11 enriched GO terms of the targets in all five formulae were found, such as oxidoreductase activity, lipid metabolic process, lipid binding, small molecule metabolic process, homeostatic process, signal transducer activity and cell proliferation.
T103 18408-18778 Sentence denotes Furthermore, the results of pathway enrichment analysis showed that the 7 KEGG pathways were significantly related to more than 4 formula groups, including dteroid biosynthesis, adipocytokine signaling pathway, neuroactive ligand-receptor interaction, steroid hormone biosynthesis, PPAR signaling pathway, arginine and proline metabolism and ABC transporters (Fig. 3 A).
T104 18779-19009 Sentence denotes In addition, TTD analysis showed that the 8 diseases were significantly association with more than 3 formula groups, such as acne, Behcet'S disease, benign prostate hyperplasia, intrahepatic cholestasis and brain injury (Fig. 3B).
T105 19010-19119 Sentence denotes However, the five formulae contained their specific (MSXG, SGMH, XCH, WLS and Others) GO, KEGG and TTD terms.
T106 19120-19513 Sentence denotes For example, neurological system process and beta-Alanine metabolism terms were specific for MXSG; membrane organization and parasitic infections of the eye terms for SGMH; circadian rhythm and hypertension terms for XCH; nucleic acid binding transcription factor activity, ovarian steroidogenesis and chronic inflammatory diseases terms for WLS; fat digestion and absorption terms for Others.
T107 19514-19582 Sentence denotes Fig. 2 Bubble plot of the GO analysis of the five formulae’ targets.
T108 19583-19657 Sentence denotes Fig. 3 Bubble plot of the KEGG/TTD analysis of the five formulae’ targets.
T109 19658-19674 Sentence denotes A: KEGG, B: TTD.
T110 19675-19880 Sentence denotes In the prediction of miRNAs in QFPD targets, MIR-183 and MIR-130A/B/301 were the highest linking terms to bind the five formulae targets and formulae Others was the highest group to bind miRNAs (Fig. 4 A).
T111 19881-20008 Sentence denotes In addition, kinase prediction revealed CDK7 were significantly enriched in formulae MSXG, SGMH, XCH, WLS and Others (Fig. 4B).
T112 20009-20168 Sentence denotes Finally, TF analysis showed that LXR was the highest linking TF to bind the four formulae targets and formulae WLS was the highest group to bind TFs (Fig. 4C).
T113 20169-20254 Sentence denotes Fig. 4 The miRNA, kinase and TF analysis of the five formulae’ targets by WebGestalt.
T114 20255-20364 Sentence denotes Chord plot showing the five formulae’ targets present in the represented enriched miRNA, kinase and TF terms.
T115 20365-20470 Sentence denotes Outer ring shows miRNA/kinase/TF term and log2 enrichment ratio (left) or five formulae grouping (right).
T116 20471-20528 Sentence denotes Chords connect miRNA/kinase/TF term with formulae groups.
T117 20529-20556 Sentence denotes A: miRNA, B: kinase, C: TF.
T118 20558-20617 Sentence denotes 3.3 Construction of PPI network and MCODE modules analysis
T119 20618-20783 Sentence denotes To further explore the functional relationship among five formulae, PPI networks were constructed through Metascape, and visual composition carried out by Cytoscape.
T120 20784-20989 Sentence denotes Firstly, the potential 192 target genes of MXSG were analyzed by PPI network, and the results showed that there were 144 nodes and 510 edges, which represented the interaction between protein and function.
T121 20990-21134 Sentence denotes The MXSG PPI network function module was confirmed by the MCODE plug-in and a list of the corresponding meaningful modules presented (Fig. 5 A).
T122 21135-21163 Sentence denotes 3 modules scores were > 2.5.
T123 21164-21180 Sentence denotes Module 1 (score:
T124 21181-21256 Sentence denotes 5.769) consisted of 13 nodes and the seed gene was COX7A1; Module 2 (score:
T125 21257-21333 Sentence denotes 4.429) consisted of 14 nodes and the seed gene was ALDH1A1; module 3 (score:
T126 21334-21388 Sentence denotes 5.0) consisted of 11 nodes and the seed gene was CNR2.
T127 21389-21588 Sentence denotes KEGG pathway enrichment analysis showed that MXSG modules were enriched in neuroactive ligand-receptor interaction, calcium signaling pathway, inflammatory mediator regulation of TRP channels, et.al.
T128 21589-21627 Sentence denotes Fig. 5 KEGG analysis of MCODE modules.
T129 21628-21770 Sentence denotes MCODE analysis was performed after the construction of the five formulae’ targets PPI; then, KEGG analysis was conducted on the MCODE modules.
T130 21771-21782 Sentence denotes A: MXSG, B:
T131 21783-21815 Sentence denotes Others, C: WLS, D: SGMH, E: XCH.
T132 21816-21958 Sentence denotes Secondly, the potential 99 target genes of Others were analyzed by PPI network, and the results showed that there were 77 nodes and 194 edges.
T133 21959-22000 Sentence denotes Only 1 module score were > 2.5 (Fig. 5B).
T134 22001-22017 Sentence denotes Module 1 (score:
T135 22018-22076 Sentence denotes 5.769) consisted of 13 nodes and the seed gene was COX7A1.
T136 22077-22237 Sentence denotes KEGG pathway enrichment analysis showed that Others modules were enriched in huntington's disease, glycolysis / gluconeogenesis, Notch signaling pathway, et.al.
T137 22238-22376 Sentence denotes Thirdly, the potential 96 target genes of WLS were analyzed by PPI network, and the results showed that there were 60 nodes and 143 edges.
T138 22377-22419 Sentence denotes Only 1 modules score were > 2.5 (Fig. 5C).
T139 22420-22436 Sentence denotes Module 1 (score:
T140 22437-22493 Sentence denotes 2.706) consisted of 17 nodes and the seed gene was CNR2.
T141 22494-22683 Sentence denotes KEGG pathway enrichment analysis showed that WLS modules were enriched in thyroid hormone signaling pathway, adipocytokine signaling pathway, neuroactive ligand-receptor interaction, et.al.
T142 22684-22826 Sentence denotes Fourthly, the potential 201 target genes of SGMH were analyzed by PPI network, and the results showed that there were 153 nodes and 505 edges.
T143 22827-22865 Sentence denotes 3 modules scores were > 2.5 (Fig. 5D).
T144 22866-22882 Sentence denotes Module 1 (score:
T145 22883-22957 Sentence denotes 3.529) consisted of 17 nodes and the seed gene was ACSS1; Module 2 (score:
T146 22958-23028 Sentence denotes 4.5) consisted of 7 nodes and the seed gene was CNR2; module 3 (score:
T147 23029-23083 Sentence denotes 3.5) consisted of 8 nodes and the seed gene was PRKCG.
T148 23084-23245 Sentence denotes KEGG pathway enrichment analysis showed that SGMH modules were enriched in insulin resistance, adipocytokine signaling pathway, Th17 cell differentiation, et.al.
T149 23246-23386 Sentence denotes At last, the potential 221 target genes of XCH were analyzed by PPI network, and the results showed that there were 166 nodes and 643 edges.
T150 23387-23425 Sentence denotes 5 modules scores were > 2.5 (Fig. 5E).
T151 23426-23442 Sentence denotes Module 1 (score:
T152 23443-23518 Sentence denotes 5.769) consisted of 13 nodes and the seed gene was COX7A1; Module 2 (score:
T153 23519-23592 Sentence denotes 2.769) consisted of 13 nodes and the seed gene was RRM1; module 3 (score:
T154 23593-23664 Sentence denotes 5.5) consisted of 12 nodes and the seed gene was CNR2; module 4 (score:
T155 23665-23739 Sentence denotes 2.909) consisted of 11 nodes and the seed gene was ACSS1; module 5 (score:
T156 23740-23794 Sentence denotes 3.0) consisted of 7 nodes and the seed gene was FFAR1.
T157 23795-23971 Sentence denotes KEGG pathway enrichment analysis showed that XCH modules were enriched in calcium signaling pathway, cGMP-PKG signaling pathway, neuroactive ligand-receptor interaction, et.al.
T158 23973-23998 Sentence denotes 3.4 Network construction
T159 23999-24134 Sentence denotes After using the BATMAN-TCM, we constructed five ingredients-target-pathway-disease networks, including MSXG, SGMH, XCH, WLS and Others.
T160 24135-24351 Sentence denotes In order to emphasize the important network elements, we showed the networks that exhibit those targets with larger than 6, 5, 8, 7 and 4 linking compounds for MSXG, SGMH, XCH, WLS and Others, respectively (Fig. 6 ).
T161 24352-24702 Sentence denotes MSXG network contained 31 key components, 50 proteins and 17 pathways; SGMH network contained 15 key components, 20 proteins and 8 pathways; WLS network contained 18 key components, 9 proteins and 4 pathways; XCH network contained 32 key components, 15 proteins and 12 pathways; Others network contained 10 key components, 13 proteins and 3 pathways.
T162 24703-24820 Sentence denotes To find the potential drugs of formulae QFPD for COVID-19, a total of 67 hub components were used for ADMET analysis.
T163 24821-24873 Sentence denotes Fig. 6 The component-target-pathway-disease network.
T164 24874-24890 Sentence denotes Purple polygons:
T165 24891-24993 Sentence denotes PubChem ID of QFPD compounds; blue pentagrams: QFPD targets; yellow circles: KEGG pathway; red square:
T166 24994-25055 Sentence denotes Therapeutic Target Database (TTD) disease term, green square:
T167 25056-25112 Sentence denotes Online Mendelian Inheritance in Man (OMIN) disease term.
T168 25113-25149 Sentence denotes A: MXSG, B: SGMH, C: WLS, D: XCH, E:
T169 25150-25288 Sentence denotes Others. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T170 25290-25335 Sentence denotes 3.5 ADMET evaluation of the 67 key compounds
T171 25336-25491 Sentence denotes Since in silico ADMET prediction can help early drug design and evaluation, ADMET properties of the 67 key compounds were predicted by SwissADME and pkCSM.
T172 25492-25686 Sentence denotes Chemical properties including molecular weight (MW), rotatable bonds count, H-bond acceptors and donors count, TPSA and leadlikeness violations were calculated by SwissADME and shown as Fig. 8A.
T173 25687-25906 Sentence denotes It is worth mentioning that 21 (31.34 %) compounds passed the stringent lead-like criteria (250 g/mol ≤ MW ≤ 350 g/mol, XLOGP ≤ 3.5 and rotatable bonds ≤ 7), which are excellent candidates for drug discovery (Fig. 7 A).
T174 25907-26032 Sentence denotes And these lead-likeness compounds were further predicted by pkCSM, with the exception of S3 (low gastrointestinal absorption)
T175 26033-26105 Sentence denotes Fig. 7 Chemical properties statistics of hub components in the formulae.
T176 26106-26108 Sentence denotes A:
T177 26109-26409 Sentence denotes Molecular weight, B: rotatable bond count, C: H-bond acceptors count, D: H-bond donors count, E: topological polar surface area (TPSA), F: leadlikeness violations, G: pharmacokinetic and toxicity evaluated parameters of 20 leadlikeness compounds by pkCSM; green = good, yellow = tolerable, red = bad.
T178 26410-26416 Sentence denotes Caco2:
T179 26417-26441 Sentence denotes Caco-2 Permeability,HIA:
T180 26442-26478 Sentence denotes Intestinal Absorption (Human), Skin:
T181 26479-26531 Sentence denotes Skin Permeability, VDss: volume of distribution, FU:
T182 26532-26562 Sentence denotes Fraction Unbound (Human), BBB:
T183 26563-26601 Sentence denotes Blood Brain Barrier permeability, CNS:
T184 26602-26641 Sentence denotes Central Nervous System permeability,TC:
T185 26642-26664 Sentence denotes Total Clearance, OCT2:
T186 26665-26727 Sentence denotes Renal Organic Cation Transporter 2, AMES: AMES toxicity, MTDD:
T187 26728-26802 Sentence denotes Maximum Tolerated Dose (Human), hERG I/II: hERG I and II Inhibitors, LD50:
T188 26803-26838 Sentence denotes Oral Rat Acute Toxicity (LD50), HT:
T189 26839-26858 Sentence denotes Hepatotoxicity, SS:
T190 26859-26882 Sentence denotes Skin Sensitisation, MT:
T191 26883-27030 Sentence denotes Minnow toxicity. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T192 27031-27158 Sentence denotes Fig. 8 Schematic (3D and 2D) representation that molecular model of specific compounds of each formulae with COVID-19 proteins.
T193 27159-27316 Sentence denotes A: M3 and E protein [ion channel], B: M3 and nsp13 [Helicase NCB site], C: S1 and nsp13 [Helicase ADP site], D: S1 and PLpro, E: X2 and Mpro, F: O2 and Mpro.
T194 27317-27345 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T195 27346-27353 Sentence denotes Others.
T196 27354-27533 Sentence denotes Regarding the absorption parameters, all 20 compounds (Table 2 ) presented a promising oral availability including the optimal Caco-2 cell permeability, HIA and skin permeability.
T197 27534-27765 Sentence denotes The drug distribution results showed that most of the compounds distributed in tissue (VDss> 0.45: tissue, VDss <−0.15: plasma) with good unbound fraction scores, thus becoming available to interact with the pharmacological target.
T198 27766-27888 Sentence denotes Only compound W5 and W11 were entirely unable to penetrate the blood-brain barrier (BBB) and central nervous system (CNS).
T199 27889-28023 Sentence denotes In addition, 15 compounds presented a good renal elimination and were not substrates of the renal organic cation transporter 2 (OCT2).
T200 28024-28279 Sentence denotes Finally, 14 compounds did not present any particular toxicity problems including AMES toxicity, maximum tolerated dose, hERG I inhibitor, hERG II inhibitor, oral rat acute toxicity (LD50), hepatotoxicity, skin sensitisation, and minnow toxicity (Fig. 7B).
T201 28280-28328 Sentence denotes Table 2 20 potential active compounds from QFPD.
T202 28329-28394 Sentence denotes Pubchem Molecular Name Structure Pubchem Molecular Name Structure
T203 28395-28455 Sentence denotes CID6918970 M3 ZINC5356864 CID10019512 S5 3-O-Methylviolanone
T204 28456-28501 Sentence denotes CID336327 M5 Medicarpin CID9064 W5 Cianidanol
T205 28502-28548 Sentence denotes CID14057197 O1 – CID182232 W11 (+)-Epicatechin
T206 28549-28605 Sentence denotes CID42607889 O2 Alysifolinone CID25721350 X1 ZINC13130930
T207 28606-28663 Sentence denotes CID3902 S1 letrozole CID14135323 X2 (2S)-dihydrobaicalein
T208 28664-28713 Sentence denotes CID821279 X4 ZINC338038 CID439246 MXO1 naringenin
T209 28714-28773 Sentence denotes CID440833 MS1 Leucocyanidol CID676152 SO1 SR-01,000,767,148
T210 28774-28836 Sentence denotes CID177149 MX16 (+)-Vestitol CID11438306 SX1 cyclo(L-Tyr-l-Phe)
T211 28837-28894 Sentence denotes CID114829 MX17 Liquiritigenin CID712316 WO1 (-)-taxifolin
T212 28895-28957 Sentence denotes CID928837 MX8 ZINC519174 CID373261 XO1 Eriodyctiol (flavanone)
T213 28958-28986 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T214 28987-28994 Sentence denotes Others.
T215 28996-29018 Sentence denotes 3.6 Molecular docking
T216 29019-29544 Sentence denotes The application of COVID-19 docking server and Discovery Studio software elucidated the interactions between the 20 lead-likeness compounds (S1, W5, MX17, MX16, W11, M5, XO1, MXO1, SO1, WO1, X4, MX8, M3, S5, SX1, O1, X2, X1, O2, MS1) and the 10 nonstructural and 2 structural proteins (Mpro, PLpro, nsp12 [RdRp with RNA], nsp12 [RdRp without RNA], nsp13 [Helicase ADP site], nsp13 [Helicase NCB site], nsp14 [ExoN], nsp14 [N7-MTase], nsp15 [endoribonuclease], nsp16 [2′-O-MTase], N protein NCB site, E protein [ion channel]).
T217 29545-29599 Sentence denotes The docking scores were depicted in Table 3, Table 4 .
T218 29600-29744 Sentence denotes The smaller of docking score, the lower of energy would be required, which means the binding between the compounds and the targets are stronger.
T219 29745-29822 Sentence denotes There are 9 compounds presenting better bonding ability than other compounds.
T220 29823-29905 Sentence denotes Table 3 Docking score between specific ingredients of QFPD and 2019-nCov proteins.
T221 29906-29948 Sentence denotes Molecule M3 M5 S1 S5 W11 W5 X1 X2 X4 O1 O2
T222 29949-30017 Sentence denotes Main Protease −7.7 −7.3 −6.8 −6.9 −7.2 −7.5 −7.1 −7.9 −7.3 −7.1 −7.4
T223 30018-30089 Sentence denotes Papain-like protease −8.7 −8.5 −9.9 −7.7 −8 −8 −8.4 −8.7 −8.2 −8.6 −8.2
T224 30090-30158 Sentence denotes RdRp with RNA −8.4 −8.5 −8.5 −8.3 −9.1 −9.1 −8.4 −8.2 −8.2 −8.3 −8.6
T225 30159-30230 Sentence denotes RdRp without RNA −6.8 −6.8 −6.9 −6.8 −6.7 −6.9 −7.1 −7.2 −6.5 −7.3 −7.1
T226 30231-30299 Sentence denotes Helicase ADP site −6.3 −6.3 −7.3 −6.5 −6 −6 −6.3 −6.5 −6.2 −6.1 −6.5
T227 30300-30372 Sentence denotes Helicase NCB site −7.9 −6.9 −7.2 −7.1 −7.2 −7.2 −7.4 −7.5 −7.3 −7.4 −7.4
T228 30373-30439 Sentence denotes Nsp14(ExoN) −6.8 −6.6 −6.3 −6.4 −6.9 −6.8 −6.7 −6.9 −6.4 −6.6 −6.9
T229 30440-30508 Sentence denotes Nsp14(N7-MTase) −8.8 −8.1 −8.5 −7.5 −8.4 −8.4 −8.3 −8.5 −8 −8.3 −8.5
T230 30509-30587 Sentence denotes Nsp15(endoribonuclease) −6.6 −6.3 −6.3 −5.9 −6.2 −6.2 −6.2 −6.3 −6.2 −6.4 −6.4
T231 30588-30660 Sentence denotes Nsp16(2′-O-MTase) −7.5 −7.4 −7.5 −7.2 −8.2 −8.2 −7.7 −7.9 −7.7 −7.9 −8.4
T232 30661-30730 Sentence denotes N protein NCB site −7.6 −7.5 −7.8 −7.6 −7.6 −7.6 −8 −8 −7.5 −7.6 −7.6
T233 30731-30806 Sentence denotes E protein(ion channel) −8.1 −7 −7.8 −6.7 −6.4 −6.4 −7.2 −7.3 −7.2 −7.1 −6.8
T234 30807-30835 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T235 30836-30843 Sentence denotes Others.
T236 30844-30935 Sentence denotes Table 4 Evaluation of the effect of QFPD on the robustness disturbance of COVID-19 network.
T237 30936-30979 Sentence denotes Topology MXSG SGMH XCH WLS Others BXTM YDBF
T238 30980-31025 Sentence denotes DTS 25.66 26.71 21.02 17.64 23.16 14.52 22.71
T239 31026-31070 Sentence denotes AC −4.63 −5.21 −3.02 −3.49 −5.38 −2.32 −3.78
T240 31071-31113 Sentence denotes APL 13.35 13.40 9.96 6.49 10.66 4.59 11.17
T241 31114-31159 Sentence denotes CoC −1.44 −1.64 −1.59 −1.30 −1.23 −1.15 −1.25
T242 31160-31205 Sentence denotes ClC −6.24 −6.46 −6.45 −6.36 −5.88 −6.46 −6.52
T243 31206-31391 Sentence denotes Average connectivity (AC), Connection centrality (CoC), Closeness centrality (ClC): the larger the quotient is, the more stable the network and, the less the influence made by the drug.
T244 31392-31567 Sentence denotes Disturbance total score (DTS), Average length of shortest path (APL), : the larger the quotient is, the less stable the network and, the larger the influence made by the drug.
T245 31568-31599 Sentence denotes Negative control formula: BXTM.
T246 31600-31631 Sentence denotes Positive control formula: YDBF.
T247 31632-32047 Sentence denotes M3 (Fig. 8A), a specific compound in formulae MXSG, showed eight interactions with E protein [ion channel] including Pi-sigma, Pi-alkyl and Alkyl, which were connected with TYR 57, ALA 32, ILE 46 and PRO 54, etc.; additionally, M3 (Fig. 8B) showed five interactions with nsp13 [Helicase NCB site] including Unfavorable Donor-Donor, Pi-alkyl and Alkyl, which were connected with ASN 559, ARG 409, LEU 42 and PRO 406.
T248 32048-32496 Sentence denotes S1 (Fig. 8C), a specific compound in formulae SGMH, showed seven interactions with nsp13 [Helicase ADP site] including H-bond interactions, van der waals, Amide-Pi stacked and Pi-alkyl, which were connected with ALA 313, ASP 374, GLN 537 and SER 289, etc.; additionally, S1 (Fig. 8D) showed five interactions with PLpro including Pi-anion, Pi-Pi stacked, Pi-Pi T-shaped and Pi-alkyl, which were connected with TYR 264, ASP 164, TYR 268 and PRO 248.
T249 32497-32721 Sentence denotes X2 (Fig. 8E), a specific compound in formulae XCH, showed seven interactions with Mpro including H-bond interactions, Pi-Donor hydrogen bond and Pi-alkyl, which were connected with MET 165, GLU 166, LEU 141 and CYS 145, etc.
T250 32722-32967 Sentence denotes O2 (Fig. 8F), a specific compound in formulae Others, showed seven interactions with Mpro including H-bond interactions, Carbon hydrogen bond, Pi-anion, Pi-sulfur and Pi-alkyl, which were connected with MET 131, GLY 71, LEU 100 and CYS 115, etc.
T251 32968-33421 Sentence denotes MS1 (Fig. 9 A), a compound in formulae MXSG and SGMH, showed eleven interactions with N protein NCB site including H-bond interactions, Pi-Donor hydrogen bond, Pi-sigma, Pi-Pi stacked and Pi-alkyl, which were connected with SER 51, THR 109, ALA 50 and PRO 42, etc.; additionally, MS1 (Fig. 9B) showed five interactions with nsp14 [ExoN] including H-bond interactions and Pi-Pi stacked, which were connected with GLU 92, PHE 190, ASP 273 and VAL 91, etc.
T252 33422-33651 Sentence denotes MX16 (Fig. 9C), a compound in formulae MXSG and XCH, showed seven interactions with nsp15 [endoribonuclease] including H-bond interactions, Alkyl and Pi-alkyl, which were connected with PRO 343, VAL 275, LYS 344 and SER 293, etc.
T253 33652-34021 Sentence denotes SX1 (Fig. 9D), a compound in formulae SGMH and XCH, showed two interactions with nsp14 [N7-MTase] including Pi-Pi stacked and Pi-alkyl, which were connected with PHE 426; additionally, SX1 (Fig. 9E) showed five interactions with nsp15 [endoribonuclease] including H-bond interactions, Alkyl and Pi-alkyl, which were connected with LYS 344, LYS 289, VAL 291 and PRO 343.
T254 34022-34542 Sentence denotes WO1 (Fig. 9F), a compound in formulae WLS and Others, showed seven interactions with nsp16 [2′-O-MTase] including H-bond interactions, Carbon hydrogen bond, Pi-Pi T-shaped, Pi-alkyl and Pi-anion, which were connected with PHE 149, CYS 115, ASP 99 and SER 74, etc.; additionally, WO1 (Fig. 9G) showed seven interactions with nsp12 [RdRp without RNA] including H-bond interactions, Carbon hydrogen bond, Unfavorable Donor-Donor, Pi-cation and Pi-anion, which were connected with THR 556, ARG 553, ASP 623 and SER 682, etc.
T255 34543-34801 Sentence denotes XO1 (Fig. 9H), a compound in formulae XCH and Others, showed ten interactions with nsp12 [RdRp with RNA] including H-bond interactions, Pi-Donor hydrogen bond, Pi-Pi T-shaped and Pi-alkyl, which were connected with CYS 813, GLY 590, LYS 593 and ASP 865, etc.
T256 34802-34931 Sentence denotes Fig. 9 Schematic (3D and 2D) representation that molecular model of common compounds of the five formulae with COVID-19 proteins.
T257 34932-35193 Sentence denotes A: MS1 and N protein NCB site, B: MS1 and nsp14 [ExoN], C: MX16 and nsp15 [endoribonuclease], D: SX1 and nsp14 [N7-MTase], E: SX1 and nsp15 [endoribonuclease], F: WO1 and nsp16 [2′-O-MTase], G: WO1 and nsp12 [RdRp without RNA], H: XO1 and nsp12 [RdRp with RNA].
T258 35194-35288 Sentence denotes MS: MXSG and SGMH, MX: MXSG and XCH, SX: SGMH and XCH, WO: WLS and Others, XO: XCH and Others.
T259 35290-35359 Sentence denotes 3.7 ACE2 and CD147 expression across tissues and co-expression genes
T260 35360-35531 Sentence denotes Since 2019-nCov may enter other tissues and organs through ACE2 and CD147 binding, we firstly explored the expression and distribution of ACE2 and CD147 across 53 tissues.
T261 35532-35715 Sentence denotes Fig. 10 A showed that the 5 top expression tissues of ACE2 were terminal ileum, testis, visceral (omentum), left ventricle and kidney cortex, which are 3 fold change higher than lung.
T262 35716-35859 Sentence denotes And the 5 top expression tissues of CD147 were testis, visceral (omentum), left ventricle, aorta, atrial appendage and transformed fibroblasts.
T263 35860-36151 Sentence denotes Then, to further understand whether QFPD only targets pneumonia or 2019-nCov, we obtained 200 co-expression genes of ACE2, 200 co-expression genes of CD147, 470 pneumonia-associated proteins, 119 HCoV-associated host proteins, and 476 co-expression genes of ACE2 in colonic epithelial cells.
T264 36152-36382 Sentence denotes Fig. 10B displayed that QFPD had some common targets with these five sets, while specific 254 targets for QFPD, indicating other mechanisms of QFPD on COVID-19 in addition to 2019-nCov, pneumonia, ACE2 and CD147 related functions.
T265 36383-36456 Sentence denotes Fig. 10 ACE2 and CD147 expression across tissues and co-expression genes.
T266 36457-36459 Sentence denotes A:
T267 36460-36518 Sentence denotes Radar plot of ACE2 and CD147 expression across 53 tissues.
T268 36519-36576 Sentence denotes The expression values were converted to base-2 logarithm.
T269 36577-36635 Sentence denotes Red triangle and square mean the top 5 expression tissues.
T270 36636-36638 Sentence denotes B:
T271 36639-36864 Sentence denotes UpSet plot of proteins among QFPD, HCoV (Host_protein), pneumonia, ACE2 co-expression genes (ACE2_database), CD147 co-expression genes (CD147_database), and ACE2 co-expression genes in colonic epithelial cells (ACE2_colonic).
T272 36865-36963 Sentence denotes The horizontal bar graph at the bottom left shows the total number of proteins for each group set.
T273 36964-37053 Sentence denotes Circles and vertical lines in the x-axis mark the corresponding data sets being compared.
T274 37054-37273 Sentence denotes The vertical bar graph at the top quantitates the number of proteins in the comparisons. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T275 37275-37374 Sentence denotes 3.8 Validation of drug positioning for QFPD against COVID-19 via the robustness of disease network
T276 37375-37509 Sentence denotes Firstly, the robustness of whole networks against formula attack was assessed to evaluate QFPD attack on the COVID-19 disease network.
T277 37510-37788 Sentence denotes Interestingly, Table 4 and Fig. 11 showed that MSXG, SGMH, XCH, WLS and Others attack on the COVID-19 network were characterized by greater disturbance score than negative control (BXTM), and increasing dependence on hub nodes, indicating greater fragility under formula attack.
T278 37789-37900 Sentence denotes In addition, SGMH, MSXG, and Others exerted higher disturbance score than the positive control (YDBF) Table 5 .
T279 37901-37992 Sentence denotes Fig. 11 Evaluation of the effect of QFPD on the robustness disturbance of COVID-19 network.
T280 37993-38098 Sentence denotes Blue normal distribution: drug attack on random networks as a null distribution for the permutation test.
T281 38099-38179 Sentence denotes Red vertical line: the disturbance rate of the drug to the real disease network.
T282 38180-38257 Sentence denotes Fist row: MXSG, second row: SGMH, third row: XCH, fourth row: WLS, fifth row:
T283 38258-38265 Sentence denotes Others.
T284 38266-38544 Sentence denotes Fist column: average connectivity, second row: average length of shortest path, third row: connection centrality, fourth row: closeness centrality. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T285 38545-38625 Sentence denotes Table 5 Docking score between common ingredients of QFPD and 2019-nCov proteins.
T286 38626-38673 Sentence denotes Molecule MS1 MX16 MX17 MX8 MXO1 SO1 SX1 WO1 XO1
T287 38674-38730 Sentence denotes Main Protease −7.6 −7 −7.8 −7.8 −7.8 −7.2 −7.1 −7.4 −7.4
T288 38731-38794 Sentence denotes Papain-like protease −8 −8.2 −8.1 −8.1 −8.2 −8.2 −9.2 −8.7 −8.3
T289 38795-38849 Sentence denotes RdRp with RNA −8.6 −8 −7.9 −7.9 −8 −8.4 −8.2 −8.8 −9.5
T290 38850-38909 Sentence denotes RdRp without RNA −7.1 −6.8 −6.8 −6.8 −7 −7.1 −6.9 −7.5 −7.1
T291 38910-38972 Sentence denotes Helicase ADP site −6.2 −6.5 −6.3 −6.1 −6.2 −6.4 −6.8 −6.2 −6.8
T292 38973-39035 Sentence denotes Helicase NCB site −7.4 −7.1 −7.2 −7.2 −7.5 −7.5 −7.4 −7.6 −7.5
T293 39036-39090 Sentence denotes Nsp14(ExoN) −7.2 −6.6 −6.6 −6.7 −6.9 −7 −6.9 −7.1 −7.1
T294 39091-39151 Sentence denotes Nsp14(N7-MTase) −8.6 −8.3 −8.4 −8.3 −8.6 −8.3 −9.4 −8.7 −8.7
T295 39152-39220 Sentence denotes Nsp15(endoribonuclease) −6.2 −6.8 −6.4 −6.4 −6.3 −6.5 −6.8 −6.4 −6.6
T296 39221-39283 Sentence denotes Nsp16(2′-O-MTase) −8.1 −7.4 −7.6 −7.8 −7.8 −8.3 −7.7 −8.4 −8.2
T297 39284-39343 Sentence denotes N protein NCB site −8.1 −7.9 −8 −8 −7.6 −7.8 −7.5 −7.7 −7.9
T298 39344-39411 Sentence denotes E protein(ion channel) −6.4 −6.9 −7.2 −7.2 −6.9 −6.9 −7.9 −6.8 −6.8
T299 39412-39440 Sentence denotes M: MXSG, S: SGMH, X: XCH, O:
T300 39441-39448 Sentence denotes Others.
T301 39449-39583 Sentence denotes Next, to illustrate the mechanism of QFPD against COVID-19, a formula-attacked target-KEGG pathway network was constructed (Fig. 12 ).
T302 39584-39937 Sentence denotes This network showed that MSXG, SGMH, XCH, WLS and Others interacted with 8 drug-attacked nodes (Cdc20, Ido1, Ifng, Il10, Il6, Ptger4, Spi1, Tnf), and 24 drug-attacked nodes in the COVID-19 network were related to Graft-versus-host disease, cytokine-cytokine receptor interaction, asthma, influenza A, inflammatory bowel disease, JAK-STAT signaling, etc.
T303 39938-39996 Sentence denotes Fig. 12 Disturbance analysis of QFPD for COVID-19 network.
T304 39997-39999 Sentence denotes A:
T305 40000-40052 Sentence denotes Venn diagram of the five formulae’ attacked targets.
T306 40053-40055 Sentence denotes B:
T307 40056-40184 Sentence denotes Formula-attacked target-KEGG pathway network; green square: formula, yellow diamond: attacked target, red circle: KEGG pathways.
T308 40185-40378 Sentence denotes The bigger the size of the nodes is, the higher the degree is. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T309 40380-40393 Sentence denotes 4 Discussion
T310 40394-40484 Sentence denotes Novel coronavirus (2019-nCov) infection is characterized by lung and immune system damage.
T311 40485-40606 Sentence denotes Severe infection can lead to acute respiratory distress syndrome (ARDS) and septicemia, and eventually lead to death [2].
T312 40607-40691 Sentence denotes In addition, a number of patients presented multi-organ damage and dysfunction [28].
T313 40692-40774 Sentence denotes However, there are no specific drugs or vaccine for the treatment of the COVID-19.
T314 40775-40897 Sentence denotes This reason may partly be that a single targeted drug cannot cure a complex disease with complex biological networks [29].
T315 40898-41119 Sentence denotes Despite the lack of strong evidence-based medicine, TCM has a good potential to complement the medical service for COVID-19, including reverting radiological changes, and shortening fever duration and hospital stay. [30].
T316 41120-41265 Sentence denotes It is observed that the total effective rate of QFPD in the treatment of pneumonia patients infected by novel coronavirus is more than 90 % [31].
T317 41266-41457 Sentence denotes Therefore, we explored the mechanism of QFPD against COVID-19 by systems pharmacology, and provided a combination strategy to explore the functional units in QFPD from a holistic perspective.
T318 41458-41576 Sentence denotes To our knowledge, this is the first study to explore the mechanisms of QFPD for COVID based on intra-functional units.
T319 41577-41921 Sentence denotes In this study, GO enrichment analysis showed that the common GO terms of MSXG, SGMH, XCH, WLS and Others targets were significant enriched in oxidoreductase activity, lipid metabolic process, lipid binding, small molecule metabolic process, and homeostatic process etc., suggesting QFPD may exert anti-viral activity through metabolic function.
T320 41922-42138 Sentence denotes In agreement with these results, a recent research has found that lipid metabolic reprograming plays an important role in virus replication, which may be an appealing and applicable target for antiviral therapy [32].
T321 42139-42371 Sentence denotes KEGG analysis showed that in addition to lipid metabolism-related pathways, endocrine system pathways were also significantly enriched in more than four formulae, including PPAR signaling pathway and adipocytokine signaling pathway.
T322 42372-42604 Sentence denotes A recent study has showed that the host can exert anti-inflammatory functions to inhibit excessive inflammatory damage through PPAR signaling pathway after H1N1 infection, thus keeping homeostasis of metabolism and development [33].
T323 42605-42910 Sentence denotes In addition, other common terms were significant enriched in more than two formulae, such as immune system process, endoplasmic reticulum, cell-cell signaling, calcium signaling pathway, vascular smooth muscle contraction, inflammatory mediator regulation of TRP channels, cardiac muscle contraction, etc.
T324 42911-43113 Sentence denotes Therefore, the multi-pathway and multi-target results of our intra functional unit of QFPD not only showed a new useful method for studying TCM, but may demonstrate the rationality of TCM compatibility.
T325 43114-43177 Sentence denotes Moreover, TCMATCOV platform was used to validate these results.
T326 43178-43580 Sentence denotes Interestingly, all the five FUs of QFPD showed higher disturbance score than negative control (BXTM), indicating that MSXG, SGMH, XCH, WLS and Others may protect COVID-19 independently, and target 8 specifically expressed drug-attacked nodes (Cdc20, Ido1, Ifng, Il10, Il6, Ptger4, Spi1, Tnf) which were related to the bacterial and viral responses, cytokine, immune system, signaling transduction, etc.
T327 43581-43835 Sentence denotes Currently, a number of studies have showed that 2019-nCov can cause multiple organs dysfunction, including liver [34], pancreas [35], kidney [36], throat and rectum [37], which may be the reason that a wide distribution of ACE2 across these tissues [38].
T328 43836-44107 Sentence denotes In agreement with these results, we found that ACE2 was highly expressed in terminal ileum, testis, adipose visceral omentum, heart left ventricle, kidney cortex and thyroid, etc., and QFPD has only 15.33 % common targets with 2019-nCov, pneumonia and ACE2 related genes.
T329 44108-44217 Sentence denotes These results indicate that the effective treatment of QFPD for COVID-19 may be through a holistic treatment.
T330 44218-44500 Sentence denotes Moreover, TTD analysis further displayed that QFPD targets were significantly enriched in many COVID-19 related disease, such as chronic inflammatory diseases, asthma, inflammatory bowel disease, chronic obstructive pulmonary disease, intrahepatic cholestasis, chronic ileitis, etc.
T331 44501-44651 Sentence denotes It is known that ADMETox prediction is an important part in evaluating if a drug can be toxic or can be absorbed during drug development process [39].
T332 44652-44891 Sentence denotes In our study, ADMETox evaluation shows that 20 compounds passed the stringent lead-like criteria (250 ≤ MW≤350 & XLOGP ≤ 3.5 & Number of rotatable bonds≤7) [40] and in silico drug-likeness test, and showed high gastrointestinal absorption.
T333 44892-45069 Sentence denotes Moreover, predicted toxicity evaluation showed that the median lethal dose (LD50) of all these ingredients was above 1600 mg/kg, thus may suggesting safety and efficacy of QFPD.
T334 45070-45404 Sentence denotes Combined with molecular docking results, 4 specific ingredients (M3, S1, X2 and O2) and 5 common ingredients (MS1, MX16, SX1, WO1 and XO1) of QFPD might be promising leading compounds with good molecular docking score for 2019-nCov structure and non-structure proteins, revealing that QFPD treated COVID-19 by multi-component synergy.
T335 45405-45479 Sentence denotes However, these newly monomer components should provide a further research.
T336 45480-45594 Sentence denotes It has been reported that host cellular microRNAs (miRNAs) are involved in the regulation of virus infection [41].
T337 45595-45726 Sentence denotes A previous study discovered that significantly up-regulated MIR301 and down-regulated MIR183/130B were found in H1N1 patients [42].
T338 45727-45916 Sentence denotes Consistent with these results, we found that MIR183 and MIR130A/B/301 are related to four functional units of QFPD, indicating these microRNAs may exert anti−COVID-19 activity through QFPD.
T339 45917-46126 Sentence denotes In addition, CDKs have played a role in the efficient replication of various viruses, including human HIV-1, papillomaviruses, human cytomegalovirus (HCMV), herpes simplex virus (HSV) type 1 and HSV-2 [43,44].
T340 46127-46358 Sentence denotes In agreement with these results, we found that CDK7 was predicted to enriched in the five formulae, suggesting that QFPD may regulate replication of COVID-19 viruses via CDK7 mediated cell cycle and RNA polymerase II transcription.
T341 46359-46537 Sentence denotes Recently, a previous study showed that LXR known to regulate cholesterol homeostasis during inflammation were differentially regulated during H1N1 influenza virus infection [45].
T342 46538-46732 Sentence denotes Based on our results that LXR was associated with MSXG, SGMH, XCH, WLS targets, we speculated that QFPD can regulate metabolic and pro-inflammatory processes to counter COVID-19 virus infection.
T343 46733-46792 Sentence denotes In summary, QFPD is effective in the treatment of COVID-19.
T344 46793-46970 Sentence denotes However, some shortcomings in our study include lack of an in-depth study of predictive monomers and key targets and pathways, thus need further validation in vivo and in vitro.
T345 46971-47237 Sentence denotes And the TCMATCOV platform uses SARS disease network, which is different from the COVID-19 disease network, and COVID-19-related cytokines are related to severe COVID-19 disease, so the results of platform analysis more reflect the potential efficacy of severe stage.
T346 47238-47393 Sentence denotes Nevertheless, this study confirms that network pharmacology can help explore the mechanism of QFPD on the treatment of COVID-19 with time- and cost-saving.
T347 47394-47586 Sentence denotes Moreover, based on our new FUNP analysis, we reveal that QFPD treat COVID-19 by a holistic treatment and multi-component synergy, and are further demonstrated by formula perturbation analysis.
T348 47587-47738 Sentence denotes In addition, this study provides possible candidate monomers of QFPD and related miRNAs, kinases and TFs with potential therapeutic effect on COVID-19.
T349 47739-47856 Sentence denotes This will hopefully provide evidence and new insights for further researches on the treatment of COVID-19 using QFPD.
T350 47858-47878 Sentence denotes Author contributions
T351 47879-48315 Sentence denotes Conceiving the research, Jian Chen and Yong-bing Cao; Data curation, Jian Chen, Wen-jie Sun, and Zhi-qiang Liang; Funding acquisition, Jian Chen, Zhi-qiang Liang, Bing-yong Cao and Ye-min Cao; Investigation, Ling-San Hu, Jian-ru Wang, and Bing-yong Cao; Methodology, Yong-kui Wang, Jiang-wei Yang and Ye-min Cao; Resources, Ling-San Hu and Yong-kui Wang; Visualization, Jian-ru Wang, Jiang-wei Yang; Writing – original draft, Jian Chen.
T352 48317-48350 Sentence denotes Declaration of Competing Interest
T353 48351-48395 Sentence denotes The authors declare no conflict of interest.
T354 48397-48412 Sentence denotes Acknowledgement
T355 48413-49052 Sentence denotes This work was supported by the 10.13039/100007219Shanghai Natural Science Foundation (17ZR1427600), National Science and Technology Major Projects for "Major New Drugs Innovation and Development" (2018ZX09201008-002-091 and 2018ZX09201008-002-092), Three-year Action Plan of "strong and excellent Chinese Medicine" in Hongkou District (HGY-MGB-2018-01-01), Shanghai Science and Technology Support Project in Biomedicine Field (18401932900), Budgetary Projects of Shanghai University of Traditional Chinese Medicine (2019LK046), Special Clinical Research Project of Health Profession of Shanghai Municipal Commission of Health (20194Y0081).

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 1713-1716 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T2 28877-28880 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T3 29205-29208 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T4 34022-34025 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T5 34301-34304 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T6 35095-35098 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T7 35126-35129 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T8 38666-38669 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690
T9 45196-45199 GlycoEpitope denotes WO1 http://www.glycoepitope.jp/epitopes/AN0690

2_test

Id Subject Object Predicate Lexical cue
32554251-32007143-6393485 2842-2843 32007143 denotes 2
32554251-22710290-6393486 4264-4265 22710290 denotes 3
32554251-16644487-6393487 4671-4672 16644487 denotes 5
32554251-25914040-6393488 4955-4956 25914040 denotes 7
32554251-17921993-6393489 5838-5839 17921993 denotes 8
32554251-17318209-6393490 6279-6281 17318209 denotes 11
32554251-30809144-6393491 6435-6437 30809144 denotes 12
32554251-24735618-6393492 7123-7125 24735618 denotes 13
32554251-17033281-6393493 7176-7178 17033281 denotes 14
32554251-22837674-6393494 7217-7219 22837674 denotes 15
32554251-26400175-6393495 7318-7320 26400175 denotes 16
32554251-26879404-6393496 7344-7346 26879404 denotes 17
32554251-15980575-6393497 8323-8325 15980575 denotes 18
32554251-12525261-6393498 8893-8895 12525261 denotes 19
32554251-14597658-6393499 9026-9028 14597658 denotes 20
32554251-28256516-6393500 9900-9902 28256516 denotes 21
32554251-25860834-6393501 10174-10176 25860834 denotes 22
32554251-30462320-6393502 11728-11730 30462320 denotes 24
32554251-31986264-6393503 12991-12993 31986264 denotes 27
32554251-30809144-6393504 13715-13717 30809144 denotes 12
32554251-32007143-6393505 40603-40604 32007143 denotes 2
32554251-31978945-6393506 40687-40689 31978945 denotes 28
32554251-30631056-6393507 42134-42136 30631056 denotes 32
32554251-21819625-6393508 42600-42602 21819625 denotes 33
32554251-31745103-6393509 44647-44649 31745103 denotes 39
32554251-23962477-6393510 45590-45592 23962477 denotes 41
32554251-12097601-6393511 46119-46121 12097601 denotes 43
32554251-23153050-6393512 46533-46535 23153050 denotes 45