PMC:7245302 / 41941-43357
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
481 | 222-226 | Gene | denotes | TLR3 | Gene:7098 |
482 | 288-292 | Gene | denotes | TLR4 | Gene:7099 |
483 | 790-794 | Gene | denotes | TLR3 | Gene:7098 |
484 | 805-809 | Gene | denotes | TLR4 | Gene:7099 |
485 | 1075-1079 | Gene | denotes | TLR4 | Gene:7099 |
486 | 1349-1353 | Gene | denotes | TLR3 | Gene:7098 |
487 | 1364-1368 | Gene | denotes | TLR4 | Gene:7099 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T194 | 935-941 | Body_part | denotes | radius | http://purl.org/sig/ont/fma/fma23463 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T284 | 167-168 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T285 | 247-248 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T286 | 282-283 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T287 | 428-429 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T288 | 824-825 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T289 | 842-843 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T290 | 854-855 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Ǻ |
T291 | 872-873 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Ǻ |
T292 | 1019-1020 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T293 | 1037-1038 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T294 | 1050-1051 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Ǻ |
T295 | 1068-1069 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Ǻ |
T296 | 1385-1386 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
T297 | 1399-1400 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T241 | 633-641 | Chemical | denotes | adjuvant | http://purl.obolibrary.org/obo/CHEBI_60809 |
T242 | 955-957 | Chemical | denotes | Rg | http://purl.obolibrary.org/obo/CHEBI_33368 |
T243 | 1091-1093 | Chemical | denotes | Rg | http://purl.obolibrary.org/obo/CHEBI_33368 |
T244 | 1227-1231 | Chemical | denotes | beta | http://purl.obolibrary.org/obo/CHEBI_10545 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T56 | 1165-1173 | http://purl.obolibrary.org/obo/GO_0007610 | denotes | behavior |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T315 | 0-193 | Sentence | denotes | The second statistical parameter computed for both complexes was the root mean square fluctuations (RMSF) that demonstrate average dynamical residue fluctuations over a specific length of time. |
T316 | 194-316 | Sentence | denotes | The mean RMSF concluded for TLR3-MEPVC system is 2.1 Å whereas, an average RMSF of 2.03 Å for TLR4-MEPVC was demonstrated. |
T317 | 317-430 | Sentence | denotes | Majority of the receptors residues are showing less variability and are satisfactory stable with mean RMSF < 3 Å. |
T318 | 431-563 | Sentence | denotes | The residues range mentioned above were reported to have higher RMSF values and revealed fluctuating throughout the simulation time. |
T319 | 564-655 | Sentence | denotes | These fluctuations are in all likelihood as an outcome of the moving adjuvant of the MEPVC. |
T320 | 656-768 | Sentence | denotes | This is supported by the fact that the mean RMSF of the MEPVC is comparatively very high than that of receptors. |
T321 | 769-875 | Sentence | denotes | The RMSF of MEPVC in TLR3-MEPVC and TLR4-MEPVC is 1.86 Å (maximum, 10.16 Å) and 7.45 Ǻ (maximum, 13.04 Ǻ). |
T322 | 876-1086 | Sentence | denotes | The receptors stability in both complexes is reaffirmed by radius of gyration (Rg) analysis that depicted stable plot with mean value of 33.97 Å (maximum, 35.62 Å) and 41.01 Ǻ (maximum, 41.65 Ǻ) for TLR4-MEPVC. |
T323 | 1087-1210 | Sentence | denotes | The Rg findings are coherent with that of RMSD in interpreting systems stable behavior and compact nature of the receptors. |
T324 | 1211-1315 | Sentence | denotes | Lastly, thermal beta factor (β-factor) indicated the same pattern of residues dynamics as shown by RMSF. |
T325 | 1316-1416 | Sentence | denotes | An average β-factor derived from TLR3-MEPVC and TLR4-MEPVC is 121.34 Ų and 123.47 Ų, respectively. |