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PMC:7245302 / 41941-43357 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
481 222-226 Gene denotes TLR3 Gene:7098
482 288-292 Gene denotes TLR4 Gene:7099
483 790-794 Gene denotes TLR3 Gene:7098
484 805-809 Gene denotes TLR4 Gene:7099
485 1075-1079 Gene denotes TLR4 Gene:7099
486 1349-1353 Gene denotes TLR3 Gene:7098
487 1364-1368 Gene denotes TLR4 Gene:7099

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T194 935-941 Body_part denotes radius http://purl.org/sig/ont/fma/fma23463

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T284 167-168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T285 247-248 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T286 282-283 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T287 428-429 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T288 824-825 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T289 842-843 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T290 854-855 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T291 872-873 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T292 1019-1020 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T293 1037-1038 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T294 1050-1051 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T295 1068-1069 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T296 1385-1386 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T297 1399-1400 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T241 633-641 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T242 955-957 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T243 1091-1093 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T244 1227-1231 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T56 1165-1173 http://purl.obolibrary.org/obo/GO_0007610 denotes behavior

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T315 0-193 Sentence denotes The second statistical parameter computed for both complexes was the root mean square fluctuations (RMSF) that demonstrate average dynamical residue fluctuations over a specific length of time.
T316 194-316 Sentence denotes The mean RMSF concluded for TLR3-MEPVC system is 2.1 Å whereas, an average RMSF of 2.03 Å for TLR4-MEPVC was demonstrated.
T317 317-430 Sentence denotes Majority of the receptors residues are showing less variability and are satisfactory stable with mean RMSF < 3 Å.
T318 431-563 Sentence denotes The residues range mentioned above were reported to have higher RMSF values and revealed fluctuating throughout the simulation time.
T319 564-655 Sentence denotes These fluctuations are in all likelihood as an outcome of the moving adjuvant of the MEPVC.
T320 656-768 Sentence denotes This is supported by the fact that the mean RMSF of the MEPVC is comparatively very high than that of receptors.
T321 769-875 Sentence denotes The RMSF of MEPVC in TLR3-MEPVC and TLR4-MEPVC is 1.86 Å (maximum, 10.16 Å) and 7.45 Ǻ (maximum, 13.04 Ǻ).
T322 876-1086 Sentence denotes The receptors stability in both complexes is reaffirmed by radius of gyration (Rg) analysis that depicted stable plot with mean value of 33.97 Å (maximum, 35.62 Å) and 41.01 Ǻ (maximum, 41.65 Ǻ) for TLR4-MEPVC.
T323 1087-1210 Sentence denotes The Rg findings are coherent with that of RMSD in interpreting systems stable behavior and compact nature of the receptors.
T324 1211-1315 Sentence denotes Lastly, thermal beta factor (β-factor) indicated the same pattern of residues dynamics as shown by RMSF.
T325 1316-1416 Sentence denotes An average β-factor derived from TLR3-MEPVC and TLR4-MEPVC is 121.34 Ų and 123.47 Ų, respectively.