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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
2 59-78 Disease denotes Coronavirus Disease MESH:D018352
3 80-88 Disease denotes COVID-19 MESH:C000657245
6 241-260 Disease denotes coronavirus disease MESH:D018352
7 262-270 Disease denotes COVID-19 MESH:C000657245
9 371-379 Disease denotes COVID-19 MESH:C000657245
11 449-460 Disease denotes EDMLNPNYEDL
20 1937-1953 Gene denotes interferon gamma Gene:3458
21 1285-1296 Species denotes coronavirus Tax:11118
22 1807-1812 Species denotes human Tax:9606
23 2284-2301 Species denotes Betacoronaviruses Tax:694002
24 950-969 Disease denotes coronavirus disease MESH:D018352
25 971-979 Disease denotes COVID-19 MESH:C000657245
26 1442-1450 Disease denotes COVID-19 MESH:C000657245
27 1623-1634 Disease denotes EDMLNPNYEDL
57 2453-2468 Species denotes Betacoronavirus Tax:694002
58 2493-2506 Species denotes Coronaviridae Tax:11118
59 2667-2672 Species denotes human Tax:9606
60 2761-2767 Species denotes humans Tax:9606
61 2777-2790 Species denotes coronaviruses Tax:11118
62 2844-2850 Species denotes humans Tax:9606
63 2867-2876 Species denotes hCoV-229E Tax:11137
64 2965-3020 Species denotes Middle East respiratory syndrome coronavirus (MERS-CoV) Tax:1335626
65 3022-3067 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
66 3069-3077 Species denotes SARS-CoV Tax:694009
67 3094-3104 Species denotes SARS-CoV 2 Tax:2697049
68 3378-3393 Species denotes Betacoronavirus Tax:694002
69 3434-3447 Species denotes coronaviruses Tax:11118
70 3487-3493 Species denotes camels Tax:9837
71 3548-3551 Species denotes CoV Tax:11118
72 3568-3574 Species denotes humans Tax:9606
73 3604-3612 Species denotes SARS-CoV Tax:694009
74 3720-3726 Species denotes humans Tax:9606
75 3812-3824 Species denotes raccoon dogs Tax:34880
76 3851-3859 Species denotes SARS-CoV Tax:694009
77 2407-2416 Disease denotes pneumonia MESH:D011014
78 2616-2635 Disease denotes coronavirus disease MESH:D018352
79 2637-2645 Disease denotes COVID-19 MESH:C000657245
80 2673-2681 Disease denotes zoonosis
81 2805-2815 Disease denotes infections MESH:D007239
82 2905-2927 Disease denotes coronavirus infections MESH:D018352
83 3108-3116 Disease denotes COVID-19 MESH:C000657245
84 3140-3148 Disease denotes COVID-19 MESH:C000657245
85 3356-3364 Disease denotes COVID-19 MESH:C000657245
113 4037-4050 Species denotes coronaviruses Tax:11118
114 4422-4430 Species denotes patients Tax:9606
115 4487-4495 Species denotes patients Tax:9606
116 4501-4504 Species denotes men Tax:9606
117 4585-4593 Species denotes patients Tax:9606
118 4868-4875 Species denotes persons Tax:9606
119 4958-4964 Species denotes people Tax:9606
120 5246-5254 Species denotes SARS-CoV Tax:694009
121 3922-3930 Disease denotes COVID-19 MESH:C000657245
122 4131-4139 Disease denotes COVID-19 MESH:C000657245
123 4284-4289 Disease denotes death MESH:D003643
124 4319-4325 Disease denotes deaths MESH:D003643
125 4664-4673 Disease denotes infection MESH:D007239
126 4738-4746 Disease denotes COVID-19 MESH:C000657245
127 4840-4848 Disease denotes infected MESH:D007239
128 4975-4984 Disease denotes infection MESH:D007239
129 5014-5023 Disease denotes infection MESH:D007239
130 5213-5221 Disease denotes COVID-19 MESH:C000657245
131 5293-5301 Disease denotes COVID-19 MESH:C000657245
132 5310-5315 Disease denotes fever MESH:D005334
133 5317-5326 Disease denotes dry cough MESH:D003371
134 5328-5347 Disease denotes shortness of breath MESH:D004417
135 5352-5359 Disease denotes dyspnea MESH:D004417
136 5361-5372 Disease denotes sore throat MESH:D010608
137 5377-5387 Disease denotes leukopenia MESH:D007970
138 5408-5416 Disease denotes COVID-19 MESH:C000657245
139 5697-5705 Disease denotes COVID-19 MESH:C000657245
141 6041-6049 Disease denotes COVID-19 MESH:C000657245
143 5929-5937 Disease denotes COVID-19 MESH:C000657245
145 6085-6093 Disease denotes COVID-19 MESH:C000657245
156 6170-6181 Species denotes coronavirus Tax:11118
157 6590-6595 Species denotes human Tax:9606
158 6768-6773 Species denotes Mouse Tax:10090
159 6775-6787 Species denotes Mus musculus Tax:10090
160 6962-6967 Species denotes mouse Tax:10090
161 7478-7490 Species denotes L. rhamnosus Tax:47715
162 7508-7520 Species denotes L. johnsonii Tax:33959
163 7542-7561 Species denotes Lactobacillus casei Tax:1582
164 7455-7468 Species denotes Lactobacillus Tax:33959
165 6232-6236 Disease denotes vssi
169 8454-8466 Disease denotes VirulentPred
170 8634-8642 Disease denotes allergic MESH:D004342
171 8718-8726 Disease denotes allergic MESH:D004342
178 9144-9147 Chemical denotes MEP
179 9303-9306 Chemical denotes MEP
181 9001-9017 Disease denotes viral infections MESH:D001102
183 11162-11176 Disease denotes hydropathicity
187 12601-12605 Gene denotes TLR4 Gene:7099
188 12610-12614 Gene denotes TLR3 Gene:7098
189 12527-12538 Disease denotes TLR3 PDB ID MESH:C537985
195 13807-13811 Gene denotes TLR4 Gene:7099
196 14237-14245 Chemical denotes hydrogen MESH:D006859
197 14289-14294 Chemical denotes water MESH:D014867
198 14926-14934 Chemical denotes hydrogen MESH:D006859
199 15249-15255 Chemical denotes carbon MESH:D002244
202 16927-16946 Disease denotes coronavirus disease MESH:D018352
203 17175-17183 Disease denotes COVID-19 MESH:C000657245
205 23457-23468 Disease denotes EDMLNPNYEDL
207 23196-23204 Disease denotes COVID-19 MESH:C000657245
209 24450-24455 Species denotes mouse Tax:10090
229 20195-20198 Gene denotes NS3 Gene:3845
230 22387-22417 Gene denotes nonstructural protein number 5 Gene:92521
231 22419-22423 Gene denotes nsp5 Gene:92521
232 17752-17757 Species denotes human Tax:9606
233 18164-18169 Species denotes human Tax:9606
234 18199-18203 Species denotes mice Tax:10090
235 18340-18344 Species denotes mice Tax:10090
236 18433-18438 Species denotes human Tax:9606
237 18547-18552 Species denotes human Tax:9606
238 18629-18633 Species denotes mice Tax:10090
239 18931-18935 Species denotes mice Tax:10090
240 18958-18962 Species denotes mice Tax:10090
241 19250-19254 Species denotes mice Tax:10090
242 21682-21693 Species denotes Coronavirus Tax:11118
243 22024-22035 Species denotes coronavirus Tax:11118
244 22511-22522 Species denotes coronavirus Tax:11118
245 21921-21926 Chemical denotes metal MESH:D008670
246 22730-22734 Chemical denotes Leu3
247 22735-22740 Chemical denotes Phe11
256 27212-27215 Gene denotes CD8 Gene:925
257 27299-27302 Gene denotes CD4 Gene:920
258 27321-27324 Gene denotes CD4 Gene:920
259 27534-27537 Gene denotes CD4 Gene:920
260 27549-27552 Gene denotes CD8 Gene:925
261 28904-28910 Species denotes humans Tax:9606
262 27860-27871 Disease denotes EDMLNPNYEDL
263 28559-28570 Disease denotes EDMLNPNYEDL
268 30000-30003 Chemical denotes CTB
269 30151-30183 Chemical denotes monosialotetrahexosylganglioside MESH:D005677
270 30323-30326 Chemical denotes CTB
271 29630-29646 Disease denotes viral infections MESH:D001102
275 31448-31453 Species denotes yeast Tax:4932
276 31459-31475 Species denotes Escherichia coli Tax:562
277 31552-31566 Disease denotes hydropathicity
290 32262-32267 Chemical denotes Leu29
291 32268-32273 Chemical denotes Gln37
292 32275-32280 Chemical denotes Ser51
293 32281-32286 Chemical denotes Gln70
294 32288-32293 Chemical denotes Glu72
295 32294-32299 Chemical denotes Gln77
296 32301-32306 Chemical denotes Glu57
297 32307-32312 Chemical denotes Ser76
298 32314-32320 Chemical denotes Val103
299 32321-32327 Chemical denotes Thr113
300 32333-32339 Chemical denotes Glu167
301 32340-32346 Chemical denotes Asp186
303 34153-34162 Chemical denotes Disulfide MESH:D004220
305 34975-34984 Chemical denotes Disulfide MESH:D004220
333 34621-34625 Gene denotes Met1 Gene:3004
334 34633-34637 Gene denotes Lys5 Gene:60496
335 34788-34792 Gene denotes Chi3 Gene:1118
336 34358-34367 Chemical denotes disulfide MESH:D004220
337 34427-34436 Chemical denotes disulfide MESH:D004220
338 34584-34593 Chemical denotes disulfide MESH:D004220
339 34626-34631 Chemical denotes Ser81
340 34638-34643 Chemical denotes Ala59
341 34645-34650 Chemical denotes Val12
342 34651-34656 Chemical denotes Asp28
343 34658-34663 Chemical denotes Ser16
344 34664-34669 Chemical denotes Asp28
345 34671-34676 Chemical denotes Thr40
346 34677-34682 Chemical denotes Ser47
347 34684-34689 Chemical denotes Val73
348 34690-34695 Chemical denotes Gln77
349 34697-34703 Chemical denotes Ala119
350 34704-34710 Chemical denotes Ala133
351 34712-34718 Chemical denotes Met122
352 34719-34725 Chemical denotes Ala133
353 34727-34733 Chemical denotes Ala126
354 34734-34740 Chemical denotes Asp129
355 34742-34748 Chemical denotes Leu156
356 34749-34755 Chemical denotes Leu163
357 34761-34767 Chemical denotes Asn159
358 34768-34774 Chemical denotes Asp162
359 34904-34913 Chemical denotes disulfide MESH:D004220
362 35339-35350 Species denotes E. coli K12 Tax:83333
363 35618-35627 Chemical denotes histidine MESH:D006639
365 38804-38808 Gene denotes TLR3 Gene:7098
367 39007-39011 Gene denotes TLR4 Gene:7099
396 35965-35969 Gene denotes TLR3 Gene:7098
397 35974-35978 Gene denotes TLR4 Gene:7099
398 36064-36068 Gene denotes TLR3 Gene:7098
399 36073-36077 Gene denotes TLR4 Gene:7099
400 36195-36200 Gene denotes NF-κB Gene:4790
401 36658-36662 Gene denotes TLR3 Gene:7098
402 38062-38066 Gene denotes TLR4 Gene:7099
403 37498-37506 Chemical denotes hydrogen MESH:D006859
404 38574-38579 Chemical denotes Pro23
405 38581-38586 Chemical denotes Glu24
406 38588-38593 Chemical denotes Ser25
407 38595-38600 Chemical denotes Asp44
408 38602-38607 Chemical denotes Lys47
409 38609-38614 Chemical denotes Asp50
410 38616-38621 Chemical denotes Asp51
411 38623-38628 Chemical denotes Arg67
412 38630-38635 Chemical denotes Arg87
413 38637-38642 Chemical denotes Glu89
414 38644-38650 Chemical denotes Pro113
415 38652-38658 Chemical denotes Gln115
416 38660-38666 Chemical denotes Asp137
417 38668-38674 Chemical denotes His159
418 38676-38682 Chemical denotes Asp160
419 38684-38690 Chemical denotes Ser184
420 38696-38702 Chemical denotes Lys186
421 38725-38730 Chemical denotes Lys20
422 38732-38737 Chemical denotes Phe64
423 38743-38749 Chemical denotes Asp114
427 39838-39843 Gene denotes IFN-g Gene:3458
428 39227-39232 Species denotes human Tax:9606
429 39317-39325 Disease denotes C-immsim MESH:C537418
431 41845-41849 Gene denotes TLR3 Gene:7098
433 41923-41927 Gene denotes TLR4 Gene:7099
454 40654-40658 Gene denotes TLR3 Gene:7098
455 40669-40673 Gene denotes TLR4 Gene:7099
456 40804-40808 Gene denotes TLR3 Gene:7098
457 40819-40823 Gene denotes TLR4 Gene:7099
458 40849-40853 Gene denotes TLR3 Gene:7098
459 40858-40862 Gene denotes TLR4 Gene:7099
460 41297-41301 Gene denotes TLR3 Gene:7098
461 41306-41310 Gene denotes TLR4 Gene:7099
462 41362-41366 Gene denotes TLR3 Gene:7098
463 41493-41497 Gene denotes TLR4 Gene:7099
464 41511-41515 Chemical denotes Glu1
465 41516-41521 Chemical denotes Ser79
466 41523-41529 Chemical denotes Hie540
467 41530-41536 Chemical denotes Asn614
468 41538-41545 Chemical denotes Gln1144
469 41546-41553 Chemical denotes Gln1209
470 41555-41562 Chemical denotes Gln1347
471 41563-41570 Chemical denotes Pro1371
472 41576-41583 Chemical denotes Lys1489
473 41584-41591 Chemical denotes Lys1491
481 42163-42167 Gene denotes TLR3 Gene:7098
482 42229-42233 Gene denotes TLR4 Gene:7099
483 42731-42735 Gene denotes TLR3 Gene:7098
484 42746-42750 Gene denotes TLR4 Gene:7099
485 43016-43020 Gene denotes TLR4 Gene:7099
486 43290-43294 Gene denotes TLR3 Gene:7098
487 43305-43309 Gene denotes TLR4 Gene:7099
489 43365-43373 Chemical denotes Hydrogen MESH:D006859
493 44149-44153 Gene denotes TLR3 Gene:7098
494 44158-44162 Gene denotes TLR4 Gene:7099
495 44091-44099 Chemical denotes hydrogen MESH:D006859
504 43905-43909 Gene denotes TLR3 Gene:7098
505 43914-43918 Gene denotes TLR4 Gene:7099
506 43388-43396 Chemical denotes Hydrogen MESH:D006859
507 43420-43428 Chemical denotes hydrogen MESH:D006859
508 43557-43565 Chemical denotes hydrogen MESH:D006859
509 43687-43695 Chemical denotes hydrogen MESH:D006859
510 43876-43884 Chemical denotes hydrogen MESH:D006859
511 44010-44018 Chemical denotes hydrogen MESH:D006859
534 44616-44620 Gene denotes TLR3 Gene:7098
535 44800-44804 Gene denotes TLR4 Gene:7099
536 44400-44409 Chemical denotes glutamine MESH:D005973
537 44414-44423 Chemical denotes aspartate MESH:D001224
538 44467-44475 Chemical denotes arginine MESH:D001120
539 44480-44486 Chemical denotes lysine MESH:D008239
540 44651-44655 Chemical denotes salt MESH:D012492
541 44709-44713 Chemical denotes Glu8
542 44715-44721 Chemical denotes Glu276
543 44723-44729 Chemical denotes Arg306
544 44731-44737 Chemical denotes Glu333
545 44749-44753 Chemical denotes Lys3
546 44755-44759 Chemical denotes Lys8
547 44761-44766 Chemical denotes Glu83
548 44768-44773 Chemical denotes Arg16
549 44838-44844 Chemical denotes Arg646
550 44846-44852 Chemical denotes Asp268
551 44854-44861 Chemical denotes Arg1396
552 44878-44882 Chemical denotes salt MESH:D012492
553 44897-44903 Chemical denotes Asp146
554 44905-44911 Chemical denotes Arg175
555 44916-44922 Chemical denotes Glu184
563 48691-48694 Gene denotes Err Gene:6541
564 49167-49172 Mutation denotes DELTA c.del
565 49130-49135 Mutation denotes DELTA c.del
566 49093-49098 Mutation denotes DELTA c.del
567 48902-48907 Mutation denotes DELTA c.del
568 48865-48870 Mutation denotes DELTA c.del
569 48828-48833 Mutation denotes DELTA c.del
572 48620-48624 Gene denotes TLR3 Gene:7098
573 48607-48611 Chemical denotes PBSA MESH:C437084
581 49368-49371 Gene denotes Err Gene:6541
582 49840-49845 Mutation denotes DELTA c.del
583 49802-49807 Mutation denotes DELTA c.del
584 49766-49771 Mutation denotes DELTA c.del
585 49577-49582 Mutation denotes DELTA c.del
586 49539-49544 Mutation denotes DELTA c.del
587 49503-49508 Mutation denotes DELTA c.del
590 49297-49301 Gene denotes TLR4 Gene:7099
591 49284-49288 Chemical denotes PBSA MESH:C437084
601 45028-45032 Gene denotes TLR3 Gene:7098
602 45043-45047 Gene denotes TLR4 Gene:7099
603 45434-45438 Gene denotes TLR3 Gene:7098
604 45573-45577 Gene denotes TLR4 Gene:7099
605 45842-45846 Gene denotes TLR3 Gene:7098
606 46277-46281 Gene denotes TLR4 Gene:7099
607 46923-46927 Gene denotes TLR3 Gene:7098
608 48002-48006 Gene denotes TLR4 Gene:7099
609 45711-45715 Gene denotes TLR3 Gene:7098
650 52548-52553 Gene denotes HAX-1 Gene:10456
651 52594-52597 Gene denotes PB1 Gene:26952
652 50084-50097 Species denotes coronaviruses Tax:11118
653 50216-50221 Species denotes human Tax:9606
654 50724-50736 Species denotes Homo sapiens Tax:9606
655 51215-51227 Species denotes Homo sapiens Tax:9606
656 51477-51483 Species denotes humans Tax:9606
657 51549-51554 Species denotes human Tax:9606
658 52168-52173 Species denotes human Tax:9606
659 52231-52235 Species denotes H5N1 Tax:102793
660 52236-52253 Species denotes influenza viruses Tax:11308
661 52274-52279 Species denotes human Tax:9606
662 52449-52453 Species denotes H5N1 Tax:102793
663 52459-52476 Species denotes influenza viruses Tax:11308
664 52491-52496 Species denotes human Tax:9606
665 52654-52660 Species denotes humans Tax:9606
666 52918-52925 Species denotes chicken Tax:9031
667 52930-52936 Species denotes turkey Tax:9103
668 52979-52984 Species denotes yeast Tax:4932
669 53118-53127 Species denotes mammalian Tax:9606
670 53186-53203 Species denotes influenza viruses Tax:11308
671 53328-53333 Species denotes human Tax:9606
672 53393-53403 Species denotes SARS-CoV-2 Tax:2697049
673 53408-53416 Species denotes SARS-CoV Tax:694009
674 53462-53472 Species denotes SARS-CoV-2 Tax:2697049
675 53478-53486 Species denotes SARS-CoV Tax:694009
676 53488-53496 Species denotes MERS-CoV Tax:1335626
677 53590-53596 Species denotes humans Tax:9606
678 53680-53685 Species denotes human Tax:9606
679 53870-53875 Species denotes human Tax:9606
680 54185-54196 Species denotes chimpanzees Tax:9598
681 54337-54349 Species denotes Homo sapiens Tax:9606
682 54517-54522 Species denotes human Tax:9606
683 53290-53299 Species denotes influenza Tax:11320
684 53511-53520 Species denotes influenza Tax:11320
685 50170-50178 Disease denotes COVID-19 MESH:C000657245
686 50428-50436 Disease denotes COVID-19 MESH:C000657245
687 53521-53531 Disease denotes infections MESH:D007239
688 53829-53848 Disease denotes infectious diseases MESH:D003141
689 53931-53953 Disease denotes coronavirus infections MESH:D018352
696 55831-55843 Species denotes Homo sapiens Tax:9606
697 56197-56203 Species denotes humans Tax:9606
698 56243-56248 Species denotes human Tax:9606
699 55144-55152 Disease denotes COVID-19 MESH:C000657245
700 55339-55347 Disease denotes allergic MESH:D004342
701 55662-55670 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 312-324 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T2 530-542 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T3 1192-1199 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T4 1336-1343 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T5 1384-1396 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T6 1491-1495 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T7 1502-1506 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T8 1546-1554 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T9 1575-1579 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T10 1701-1713 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T11 1813-1826 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T12 2573-2576 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T13 2823-2840 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T14 3796-3800 Body_part denotes palm http://purl.org/sig/ont/fma/fma24920
T15 3866-3869 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 3931-3934 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T17 5366-5372 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T18 5577-5584 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T19 6137-6145 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T20 6255-6265 Body_part denotes Nucleotide http://purl.org/sig/ont/fma/fma82740
T21 6522-6530 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T22 6623-6631 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T23 6846-6854 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T24 6980-6988 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T25 7098-7106 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T26 7207-7215 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T27 7280-7287 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T28 7383-7390 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T29 7622-7625 Body_part denotes gut http://purl.org/sig/ont/fma/fma7199
T30 7655-7659 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T31 7881-7886 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 7926-7930 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T33 8017-8049 Body_part denotes major histocompatibility complex http://purl.org/sig/ont/fma/fma84079
T34 8051-8054 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T35 8233-8237 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T36 8248-8252 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T37 9545-9552 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T38 10627-10635 Body_part denotes ribosome http://purl.org/sig/ont/fma/fma66867
T39 10999-11009 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T40 11099-11101 Body_part denotes pl http://purl.org/sig/ont/fma/fma273007
T41 11336-11343 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T42 11356-11363 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T43 11855-11867 Body_part denotes compartments http://purl.org/sig/ont/fma/fma76577
T44 11876-11887 Body_part denotes bone marrow http://purl.org/sig/ont/fma/fma9608
T45 11898-11909 Body_part denotes lymph nodes http://purl.org/sig/ont/fma/fma5034
T46 11898-11903 Body_part denotes lymph http://purl.org/sig/ont/fma/fma9671
T47 11915-11921 Body_part denotes thymus http://purl.org/sig/ont/fma/fma9607
T48 12064-12067 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T49 12081-12084 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T50 12109-12112 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T51 12131-12134 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T52 12569-12576 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T53 14339-14341 Body_part denotes Å2 http://purl.org/sig/ont/fma/fma66595
T54 14459-14461 Body_part denotes Å2 http://purl.org/sig/ont/fma/fma66595
T55 14596-14598 Body_part denotes Å2 http://purl.org/sig/ont/fma/fma66595
T56 14735-14737 Body_part denotes Å2 http://purl.org/sig/ont/fma/fma66595
T57 16874-16881 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T58 16971-16981 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T59 16986-16993 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T60 17207-17214 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T61 17658-17665 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T62 17832-17839 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T63 17980-17988 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T64 18565-18573 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T65 18634-18642 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T66 18944-18952 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T67 18975-18983 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T68 19267-19275 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T69 19426-19434 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T70 19436-19443 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T71 19579-19587 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T72 19670-19678 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T73 19902-19914 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T74 20044-20051 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T75 20125-20132 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T76 20187-20194 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T77 20827-20840 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T78 21057-21064 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T79 21115-21122 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T80 21299-21306 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T81 21364-21372 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T82 21473-21477 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T83 21501-21509 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T84 21556-21568 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T85 21578-21590 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T86 21765-21768 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T87 21802-21805 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T88 21816-21819 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T89 21878-21881 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T90 21892-21895 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T91 21941-21944 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T92 22006-22013 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T93 22073-22076 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T94 22085-22092 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T95 22362-22370 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T96 22401-22408 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T97 22529-22541 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T98 22667-22679 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T99 22768-22780 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T100 22931-22939 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T101 23116-23120 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T102 23131-23135 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T103 23206-23213 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T104 23229-23233 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T105 23550-23562 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T106 24376-24384 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T107 24428-24436 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T108 24468-24476 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T109 24498-24506 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T110 24526-24534 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T111 24603-24607 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T112 24775-24788 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T113 25229-25232 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T114 25241-25254 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T115 25268-25279 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T116 25302-25307 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 25340-25344 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T118 25388-25393 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T119 25531-25536 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T120 25567-25572 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T121 25777-25781 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T122 25822-25826 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T123 25860-25867 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T124 25994-25998 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T125 26157-26169 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T126 26182-26194 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T127 26246-26251 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T128 26314-26318 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T129 26358-26363 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T130 26384-26394 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T131 26510-26518 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T132 26544-26548 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T133 26704-26707 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T134 26714-26717 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T135 26801-26813 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T136 26823-26835 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T137 26868-26875 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T138 26938-26942 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T139 27035-27039 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T140 27112-27136 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T141 27131-27136 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T142 27146-27149 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T143 27188-27191 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T144 27217-27240 Body_part denotes cytotoxic T lymphocytes http://purl.org/sig/ont/fma/fma70573
T145 27274-27277 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T146 27305-27310 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T147 27327-27332 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T148 27346-27360 Body_part denotes helper T-cells http://purl.org/sig/ont/fma/fma70572
T149 27355-27360 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T150 27528-27532 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T151 27540-27544 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T152 27555-27559 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T153 27753-27760 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T154 27914-27926 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T155 28008-28020 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T156 28206-28211 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T157 28654-28666 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T158 28756-28768 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T159 30208-30212 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T160 30230-30233 Body_part denotes gut http://purl.org/sig/ont/fma/fma7199
T161 30234-30250 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T162 30245-30250 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T163 30252-30276 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T164 30271-30276 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 30278-30287 Body_part denotes dendritic http://purl.org/sig/ont/fma/fma67314
T166 30292-30303 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T167 30311-30316 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T168 31043-31054 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T169 31868-31873 Body_part denotes helix http://purl.org/sig/ont/fma/fma60992
T170 31889-31894 Body_part denotes helix http://purl.org/sig/ont/fma/fma60992
T171 31905-31910 Body_part denotes helix http://purl.org/sig/ont/fma/fma60992
T172 32215-32225 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T173 33072-33080 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T174 33843-33851 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T175 34194-34201 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T176 34414-34422 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T177 35618-35627 Body_part denotes histidine http://purl.org/sig/ont/fma/fma82755
T178 36025-36032 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T179 36240-36249 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T180 37226-37230 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T181 39233-39246 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T182 39476-39479 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T183 39484-39487 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T184 39548-39551 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T185 39552-39560 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T186 39569-39577 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T187 39723-39731 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T188 39829-39837 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T189 39944-39957 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T190 39988-39998 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T191 40013-40022 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T192 40027-40039 Body_part denotes interleukins http://purl.org/sig/ont/fma/fma86578
T193 40376-40382 Body_part denotes radius http://purl.org/sig/ont/fma/fma23463
T194 42876-42882 Body_part denotes radius http://purl.org/sig/ont/fma/fma23463
T195 44211-44218 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T196 44284-44295 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T197 44400-44409 Body_part denotes glutamine http://purl.org/sig/ont/fma/fma82752
T198 44467-44475 Body_part denotes arginine http://purl.org/sig/ont/fma/fma82763
T199 44480-44486 Body_part denotes lysine http://purl.org/sig/ont/fma/fma82758
T200 49932-49945 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T201 50976-50980 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T202 53089-53093 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T203 55382-55387 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T204 57117-57125 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1813-1826 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T2 2823-2840 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T3 5366-5372 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T4 11876-11887 Body_part denotes bone marrow http://purl.obolibrary.org/obo/UBERON_0002371
T5 11898-11909 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T6 11898-11903 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T7 11915-11921 Body_part denotes thymus http://purl.obolibrary.org/obo/UBERON_0002370
T8 15221-15226 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T9 15332-15337 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T10 15407-15412 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T11 20827-20840 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T12 24775-24788 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T13 25229-25232 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T14 25241-25254 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T15 31868-31873 Body_part denotes helix http://purl.obolibrary.org/obo/UBERON_0002488
T16 31889-31894 Body_part denotes helix http://purl.obolibrary.org/obo/UBERON_0002488
T17 31905-31910 Body_part denotes helix http://purl.obolibrary.org/obo/UBERON_0002488
T18 39233-39246 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T19 39511-39516 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T20 39662-39667 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T21 39944-39957 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T22 49932-49945 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 80-88 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 262-270 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 371-379 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 971-979 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 1442-1450 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 2407-2416 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T7 2637-2645 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 2805-2840 Disease denotes infections of the respiratory tract http://purl.obolibrary.org/obo/MONDO_0024355
T9 2917-2927 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T10 3022-3055 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T11 3069-3077 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 3094-3102 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 3108-3116 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 3140-3148 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 3356-3364 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 3458-3462 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 3604-3612 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T18 3851-3859 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 3922-3930 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 4131-4139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 4664-4673 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 4738-4746 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 4797-4801 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T24 4975-4984 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T25 5014-5023 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 5213-5221 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 5246-5254 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 5293-5301 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 5361-5372 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T30 5377-5387 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T31 5408-5416 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 5697-5705 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 5929-5937 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 6041-6049 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T35 6085-6093 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 8634-8642 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T37 8653-8656 Disease denotes CLC http://purl.obolibrary.org/obo/MONDO_0004315
T38 8718-8726 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T39 9001-9017 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T40 9348-9355 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T41 17175-17183 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 20195-20198 Disease denotes NS3 http://purl.obolibrary.org/obo/MONDO_0012371
T43 20464-20474 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T44 21262-21270 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T45 22552-22562 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T46 23196-23204 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 29331-29341 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T48 29630-29646 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T49 29889-29896 Disease denotes Cholera http://purl.obolibrary.org/obo/MONDO_0015766
T50 30024-30031 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T51 50170-50178 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 50428-50436 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T53 52236-52245 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T54 52459-52468 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T55 53186-53195 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T56 53284-53299 Disease denotes avian influenza http://purl.obolibrary.org/obo/MONDO_0018695
T57 53290-53299 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T58 53393-53401 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 53408-53416 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 53462-53470 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 53478-53486 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 53511-53520 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T63 53521-53531 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T64 53760-53770 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T65 53829-53839 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T66 53943-53953 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T67 55144-55152 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 55339-55347 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T69 55662-55670 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 10-11 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 180-181 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T3 592-593 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T4 629-632 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T5 770-789 http://purl.obolibrary.org/obo/GO_0043235 denotes receptors complexes
T6 1045-1046 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1066-1072 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T8 1103-1108 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T9 1131-1132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1489-1495 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T11 1500-1506 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T12 1567-1568 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T13 1573-1579 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T14 1762-1763 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 1807-1812 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T16 1813-1826 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T17 1937-1953 http://purl.obolibrary.org/obo/PR_000000017 denotes interferon gamma
T18 1975-1978 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T19 2021-2027 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T20 2177-2185 http://purl.obolibrary.org/obo/CLO_0009985 denotes focusing
T21 2332-2337 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T22 2386-2387 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T23 2546-2553 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T24 2659-2660 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 2667-2672 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T26 2719-2720 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 2761-2767 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T28 2844-2850 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T29 3271-3276 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3] [4
T30 3326-3329 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T31 3487-3493 http://purl.obolibrary.org/obo/NCBITaxon_9837 denotes camels
T32 3498-3502 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T33 3557-3564 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T34 3568-3574 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T35 3618-3622 http://purl.obolibrary.org/obo/CLO_0001550 denotes a 10
T36 3670-3675 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 3720-3726 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T38 3761-3762 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T39 3812-3819 http://purl.obolibrary.org/obo/NCBITaxon_9654 denotes raccoon
T40 3935-3940 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T41 3949-3950 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T42 4082-4094 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T43 4149-4150 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 4419-4421 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T45 4994-5002 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T46 5073-5078 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T47 5222-5225 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T48 5464-5465 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T49 5566-5567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 5601-5606 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T51 5679-5680 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 5747-5748 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 5911-5912 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 6226-6231 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T55 6239-6244 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T56 6590-6595 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T57 6740-6741 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 6768-6773 http://purl.obolibrary.org/obo/CLO_0007836 denotes Mouse
T59 6775-6787 http://purl.obolibrary.org/obo/NCBITaxon_10090 denotes Mus musculus
T60 6944-6946 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T61 6962-6967 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T62 7421-7429 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T63 7571-7575 http://purl.obolibrary.org/obo/CLO_0001106 denotes 1582
T64 7622-7625 http://purl.obolibrary.org/obo/UBERON_0001007 denotes gut
T65 7622-7625 http://purl.obolibrary.org/obo/UBERON_0001555 denotes gut
T66 7622-7625 http://www.ebi.ac.uk/efo/EFO_0000834 denotes gut
T67 7626-7634 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T68 7636-7638 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T69 7647-7648 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T70 7653-7659 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T71 7815-7817 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T72 7879-7886 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cells
T73 7924-7930 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T74 8231-8237 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T75 8246-8252 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T76 8489-8491 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T77 8653-8656 http://purl.obolibrary.org/obo/CLO_0002494 denotes CLC
T78 8833-8840 http://purl.obolibrary.org/obo/PR_000018263 denotes Peptide
T79 8922-8923 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T80 8938-8945 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T81 8972-8973 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 9065-9072 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T83 9142-9143 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 9335-9336 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T85 9398-9399 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 9414-9421 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T87 9449-9451 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T88 9510-9511 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 9829-9831 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T90 10067-10069 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T91 10083-10091 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T92 10157-10159 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T93 10479-10481 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T94 10547-10550 http://purl.obolibrary.org/obo/CLO_0051142 denotes rho
T95 11614-11615 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 11868-11880 http://purl.obolibrary.org/obo/UBERON_0001474 denotes such as bone
T97 11898-11909 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T98 11915-11921 http://purl.obolibrary.org/obo/UBERON_0002370 denotes thymus
T99 11923-11925 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T100 12079-12080 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T101 12107-12108 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T102 12340-12341 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 12395-12396 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 13106-13108 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T105 13334-13336 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T106 13515-13516 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 13542-13544 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T108 13718-13720 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T109 13868-13869 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T110 13958-13963 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T111 14082-14084 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T112 14339-14341 http://purl.obolibrary.org/obo/CLO_0001562 denotes Å2
T113 14339-14341 http://purl.obolibrary.org/obo/CLO_0001563 denotes Å2
T114 14459-14461 http://purl.obolibrary.org/obo/CLO_0001562 denotes Å2
T115 14459-14461 http://purl.obolibrary.org/obo/CLO_0001563 denotes Å2
T116 14596-14598 http://purl.obolibrary.org/obo/CLO_0001562 denotes Å2
T117 14596-14598 http://purl.obolibrary.org/obo/CLO_0001563 denotes Å2
T118 14735-14737 http://purl.obolibrary.org/obo/CLO_0001562 denotes Å2
T119 14735-14737 http://purl.obolibrary.org/obo/CLO_0001563 denotes Å2
T120 14887-14889 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T121 15020-15022 http://purl.obolibrary.org/obo/CLO_0008491 denotes ps
T122 15028-15029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 15156-15159 http://purl.obolibrary.org/obo/CLO_0001562 denotes Å 2
T124 15156-15159 http://purl.obolibrary.org/obo/CLO_0001563 denotes Å 2
T125 15207-15209 http://purl.obolibrary.org/obo/CLO_0008491 denotes ps
T126 15325-15326 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 15400-15401 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 15511-15512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T129 15528-15529 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T130 15602-15603 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 15752-15754 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T132 15902-15909 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T133 16925-16926 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 17144-17145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T135 17155-17162 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T136 17319-17322 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T137 17385-17390 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T138 17752-17757 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T139 17826-17831 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T140 18164-18169 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T141 18297-18303 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T142 18312-18314 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T143 18351-18357 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T144 18433-18438 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T145 18474-18475 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 18547-18552 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T147 19174-19179 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T148 19893-19901 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T149 20035-20043 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T150 20440-20441 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T151 20530-20531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 20592-20595 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T153 20784-20794 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T154 20827-20840 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T155 20914-20922 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T156 20927-20932 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T157 21027-21032 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T158 21171-21172 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 21471-21477 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T160 21724-21734 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T161 21780-21790 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T162 21907-21915 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T163 21964-21974 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T164 21989-21990 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T165 22055-22056 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 22108-22109 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 22238-22248 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T168 22266-22270 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3′-5
T169 22583-22584 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T170 22615-22623 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T171 22712-22713 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 23114-23120 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T173 23129-23135 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T174 23221-23222 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T175 23227-23233 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T176 24386-24389 http://purl.obolibrary.org/obo/CLO_0009390 denotes TPs
T177 24450-24455 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T178 24595-24596 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T179 24601-24607 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T180 24683-24684 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T181 24750-24751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T182 24775-24788 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T183 25229-25232 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T184 25241-25254 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T185 25294-25295 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T186 25300-25307 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T187 25340-25344 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T188 25378-25380 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T189 25388-25393 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T190 25523-25524 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T191 25529-25536 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T192 25542-25552 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T193 25567-25572 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T194 25649-25659 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T195 25660-25667 http://purl.obolibrary.org/obo/SO_0000418 denotes signals
T196 25775-25781 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T197 25820-25826 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T198 25992-25998 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T199 26144-26146 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T200 26244-26251 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cells
T201 26312-26318 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T202 26344-26354 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T203 26356-26363 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cells
T204 26465-26473 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T205 26542-26548 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T206 26732-26734 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T207 26936-26942 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T208 27033-27039 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T209 27131-27136 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T210 27212-27215 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T211 27299-27302 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T212 27303-27310 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T213 27321-27324 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T214 27325-27332 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T215 27346-27360 http://purl.obolibrary.org/obo/CL_0000912 denotes helper T-cells
T216 27526-27532 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cell
T217 27534-27537 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T218 27538-27544 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T219 27549-27552 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T220 27553-27559 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T221 27587-27588 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 28206-28211 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T223 28904-28910 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T224 29476-29477 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T225 29911-29912 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T226 30098-30099 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T227 30208-30218 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T228 30230-30233 http://purl.obolibrary.org/obo/UBERON_0001007 denotes gut
T229 30230-30233 http://purl.obolibrary.org/obo/UBERON_0001555 denotes gut
T230 30230-30233 http://www.ebi.ac.uk/efo/EFO_0000834 denotes gut
T231 30234-30244 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T232 30245-30250 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T233 30271-30276 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T234 30309-30316 http://purl.obolibrary.org/obo/CL_0000236 denotes B-cells
T235 30330-30331 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 30420-30429 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T237 30420-30429 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T238 30668-30669 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T239 31253-31256 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T240 31984-31988 http://purl.obolibrary.org/obo/CLO_0001927 denotes bend
T241 32395-32396 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T242 32970-32971 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T243 33142-33143 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T244 33419-33422 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4.C
T245 33487-33488 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T246 33653-33654 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T247 33766-33767 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T248 34530-34532 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T249 34621-34625 http://purl.obolibrary.org/obo/CLO_0052870 denotes Met1
T250 34788-34792 http://purl.obolibrary.org/obo/CLO_0051177 denotes Chi3
T251 35197-35199 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T252 35354-35355 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T253 36023-36024 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T254 36033-36040 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T255 36162-36170 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T256 36185-36194 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T257 36199-36200 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T258 36433-36443 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T259 36794-36795 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T260 37513-37515 http://purl.obolibrary.org/obo/CLO_0003622 denotes HB
T261 37607-37608 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T262 38297-38299 http://purl.obolibrary.org/obo/CLO_0003622 denotes HB
T263 38508-38509 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T264 38562-38563 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T265 38844-38851 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T266 39047-39054 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T267 39227-39232 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T268 39233-39246 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T269 39499-39502 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T270 39503-39504 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T271 39944-39957 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T272 39985-39986 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T273 40006-40007 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T274 40041-40042 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T275 40246-40248 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T276 40479-40481 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T277 40736-40737 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T278 40753-40754 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T279 40765-40766 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T280 40782-40783 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T281 40921-40922 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T282 41425-41427 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T283 41790-41792 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T284 42108-42109 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T285 42188-42189 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T286 42223-42224 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T287 42369-42370 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T288 42765-42766 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T289 42783-42784 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T290 42795-42796 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T291 42813-42814 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T292 42960-42961 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T293 42978-42979 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T294 42991-42992 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T295 43009-43010 http://purl.obolibrary.org/obo/CLO_0001020 denotes Ǻ
T296 43326-43327 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T297 43340-43341 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T298 43418-43419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T299 43446-43447 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T300 43530-43531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T301 43761-43762 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T302 43923-43925 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T303 44209-44210 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T304 44559-44560 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T305 44690-44691 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T306 48410-48411 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T307 49932-49945 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T308 49970-49971 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T309 49981-49988 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T310 50008-50009 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T311 50037-50038 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T312 50148-50149 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T313 50216-50221 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T314 50304-50305 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 50440-50441 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T316 50464-50465 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T317 50657-50664 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T318 50669-50675 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T319 50687-50694 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T320 50698-50706 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T321 50724-50736 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Homo sapiens
T322 50821-50828 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T323 50976-50980 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T324 50996-51004 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T325 51100-51101 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 51130-51139 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T327 51130-51139 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T328 51215-51227 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Homo sapiens
T329 51417-51418 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T330 51477-51483 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T331 51493-51494 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 51549-51554 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T333 51648-51655 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T334 51738-51741 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T335 51919-51920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T336 52168-52180 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human beings
T337 52182-52183 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T338 52246-52253 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T339 52274-52279 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T340 52284-52290 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T341 52410-52413 http://purl.obolibrary.org/obo/CLO_0008385 denotes PB1
T342 52414-52416 http://purl.obolibrary.org/obo/CLO_0002972 denotes F2
T343 52418-52419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T344 52432-52439 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T345 52469-52476 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T346 52489-52490 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T347 52491-52496 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T348 52581-52582 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T349 52594-52597 http://purl.obolibrary.org/obo/CLO_0008385 denotes PB1
T350 52598-52600 http://purl.obolibrary.org/obo/CLO_0002972 denotes F2
T351 52632-52639 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T352 52654-52660 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T353 52698-52699 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T354 52870-52878 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T355 52894-52895 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T356 52918-52925 http://purl.obolibrary.org/obo/NCBITaxon_9031 denotes chicken
T357 52930-52936 http://purl.obolibrary.org/obo/NCBITaxon_9005 denotes turkey
T358 52943-52949 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T359 52958-52966 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T360 53070-53071 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T361 53089-53093 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T362 53128-53136 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T363 53152-53154 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T364 53196-53203 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T365 53209-53210 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T366 53316-53317 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 53328-53333 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T368 53568-53575 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T369 53590-53596 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T370 53680-53685 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T371 53690-53696 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T372 53711-53716 http://purl.obolibrary.org/obo/UBERON_0001456 denotes faced
T373 53717-53718 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T374 53870-53875 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T375 54145-54148 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T376 54152-54155 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T377 54185-54196 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes chimpanzees
T378 54337-54349 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Homo sapiens
T379 54368-54369 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T380 54517-54522 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T381 54523-54526 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T382 54630-54631 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T383 54764-54765 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T384 54905-54908 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T385 54940-54941 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T386 55271-55278 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T387 55374-55375 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T388 55380-55387 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T389 55404-55405 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T390 55420-55427 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T391 55640-55641 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T392 55704-55711 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T393 55727-55733 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T394 55831-55843 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Homo sapiens
T395 55865-55866 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T396 55981-55982 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T397 56034-56040 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T398 56197-56203 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T399 56223-56230 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T400 56243-56248 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T401 56359-56360 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 194-201 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T2 312-324 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T3 530-542 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T4 580-587 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T5 1192-1199 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T6 1336-1343 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7 1384-1396 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T8 1546-1554 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T9 1701-1713 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T10 1937-1947 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T11 1948-1953 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T12 2472-2477 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T13 5577-5584 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T14 5616-5623 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T15 6137-6145 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T16 6255-6265 Chemical denotes Nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T17 6522-6530 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T18 6846-6854 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T19 6980-6988 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20 7207-7215 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T21 7383-7390 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T22 7739-7746 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T23 8068-8070 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T24 8833-8840 Chemical denotes Peptide http://purl.obolibrary.org/obo/CHEBI_16670
T25 8842-8845 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T29 8930-8937 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T30 8938-8945 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T31 8947-8950 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T35 9065-9072 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T36 9144-9147 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T40 9165-9174 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T41 9203-9206 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T45 9303-9306 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T49 9311-9319 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T50 9356-9361 Chemical denotes toxin http://purl.obolibrary.org/obo/CHEBI_27026
T51 9380-9383 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T55 9406-9413 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T56 9414-9421 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T57 9545-9552 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58 9757-9766 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T59 10235-10237 Chemical denotes GC http://purl.obolibrary.org/obo/CHEBI_73890
T60 10367-10369 Chemical denotes GC http://purl.obolibrary.org/obo/CHEBI_73890
T61 10999-11009 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T62 10999-11004 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T63 11005-11009 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T64 11336-11343 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T65 11356-11363 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66 12128-12130 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T67 12141-12143 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T68 12514-12516 Chemical denotes ID http://purl.obolibrary.org/obo/CHEBI_141439
T69 12536-12538 Chemical denotes ID http://purl.obolibrary.org/obo/CHEBI_141439
T70 12569-12576 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T71 13083-13085 Chemical denotes DS http://purl.obolibrary.org/obo/CHEBI_62097|http://purl.obolibrary.org/obo/CHEBI_73454
T73 13334-13336 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T74 13542-13544 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T75 14041-14043 Chemical denotes Na http://purl.obolibrary.org/obo/CHEBI_26708
T76 14053-14057 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T77 14082-14084 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T78 14237-14245 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T79 14246-14251 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T80 14289-14294 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T81 14392-14397 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T82 14468-14473 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T83 14530-14535 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T84 14744-14749 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T85 14834-14839 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T86 14926-14934 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T87 15166-15171 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T88 15249-15255 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T90 15256-15261 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T91 15737-15739 Chemical denotes DS http://purl.obolibrary.org/obo/CHEBI_62097|http://purl.obolibrary.org/obo/CHEBI_73454
T93 15894-15901 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T94 15902-15909 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T95 16053-16061 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T96 16577-16583 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T97 16874-16881 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T98 16971-16981 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T99 16986-16993 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T100 17155-17162 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T101 17207-17214 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T102 17658-17665 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T103 17832-17839 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T104 17980-17988 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T105 18565-18573 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T106 18634-18642 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T107 18944-18952 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T108 18975-18983 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T109 19267-19275 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T110 19426-19434 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T111 19436-19443 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T112 19579-19587 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T113 19670-19678 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T114 19902-19914 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T115 20044-20051 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T116 20125-20132 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T117 20187-20194 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T118 20442-20450 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T119 20741-20748 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T120 21115-21122 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T121 21299-21306 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T122 21364-21372 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T123 21501-21509 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T124 21556-21568 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T125 21578-21590 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T126 21833-21841 Chemical denotes cofactor http://purl.obolibrary.org/obo/CHEBI_23357
T127 21927-21930 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T128 22006-22013 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T129 22085-22092 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T130 22119-22127 Chemical denotes cofactor http://purl.obolibrary.org/obo/CHEBI_23357
T131 22362-22370 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T132 22401-22408 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T133 22529-22541 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T134 22667-22679 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T135 22768-22780 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T136 22931-22939 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T137 23206-23213 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T138 23387-23395 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T139 23430-23438 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T140 23486-23494 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T141 23528-23536 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T142 23550-23562 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T143 23592-23600 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T144 24376-24384 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T145 24428-24436 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T146 24468-24476 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T147 24498-24506 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T148 24526-24534 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T149 24661-24669 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T150 24828-24835 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T151 25441-25449 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T152 25455-25463 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T153 25582-25589 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T154 25860-25867 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T155 26157-26169 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T156 26182-26194 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T157 26279-26286 Chemical denotes solvent http://purl.obolibrary.org/obo/CHEBI_46787
T158 26295-26303 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T159 26454-26460 Chemical denotes toxins http://purl.obolibrary.org/obo/CHEBI_27026
T160 26510-26518 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T161 26718-26720 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T162 26801-26813 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T163 26823-26835 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T164 26868-26875 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T165 27085-27093 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T166 27112-27119 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T167 27150-27159 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T168 27278-27280 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T169 27753-27760 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T170 27914-27926 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T171 28008-28020 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T172 28338-28345 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T173 28654-28666 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T174 28756-28768 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T175 29232-29240 Chemical denotes allergen http://purl.obolibrary.org/obo/CHEBI_50904
T176 29478-29481 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T180 29557-29560 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T184 29820-29827 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T185 29838-29841 Chemical denotes MEP http://purl.obolibrary.org/obo/CHEBI_34757|http://purl.obolibrary.org/obo/CHEBI_42383|http://purl.obolibrary.org/obo/CHEBI_59759|http://purl.obolibrary.org/obo/CHEBI_59760
T189 29877-29885 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T190 29897-29902 Chemical denotes toxin http://purl.obolibrary.org/obo/CHEBI_27026
T191 30032-30037 Chemical denotes toxin http://purl.obolibrary.org/obo/CHEBI_27026
T192 30252-30259 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T193 30355-30363 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T194 30452-30460 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T195 30595-30603 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T196 31043-31054 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T197 31043-31048 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T198 31049-31054 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T199 31086-31091 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T200 31862-31867 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T201 31902-31904 Chemical denotes Pi http://purl.obolibrary.org/obo/CHEBI_35780
T202 31918-31922 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T203 31964-31968 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T204 32215-32225 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T205 32215-32220 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T206 32221-32225 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T207 33072-33080 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T208 33611-33619 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T209 33843-33851 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T210 34194-34201 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T211 34358-34367 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T212 34414-34422 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T213 34427-34436 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T214 34584-34593 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T215 34904-34913 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T216 35418-35420 Chemical denotes GC http://purl.obolibrary.org/obo/CHEBI_73890
T217 35618-35627 Chemical denotes histidine http://purl.obolibrary.org/obo/CHEBI_27570
T218 36025-36032 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T219 36033-36040 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T220 36195-36197 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T223 36411-36421 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T224 36547-36555 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T225 36852-36861 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T226 36899-36908 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T227 37056-37065 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T228 37279-37287 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T229 37498-37506 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T230 37700-37708 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T231 38090-38098 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T232 39865-39872 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T233 39976-39983 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T234 40027-40039 Chemical denotes interleukins http://purl.obolibrary.org/obo/CHEBI_52998
T235 40063-40070 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T236 40246-40248 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T237 40396-40398 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T238 40409-40413 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T239 40479-40481 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T240 40554-40556 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T241 42574-42582 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T242 42896-42898 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T243 43032-43034 Chemical denotes Rg http://purl.obolibrary.org/obo/CHEBI_33368
T244 43168-43172 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T245 43365-43373 Chemical denotes Hydrogen http://purl.obolibrary.org/obo/CHEBI_18276
T246 43388-43396 Chemical denotes Hydrogen http://purl.obolibrary.org/obo/CHEBI_18276
T247 43420-43433 Chemical denotes hydrogen atom http://purl.obolibrary.org/obo/CHEBI_29305|http://purl.obolibrary.org/obo/CHEBI_49637
T249 43429-43433 Chemical denotes atom http://purl.obolibrary.org/obo/CHEBI_33250
T250 43471-43475 Chemical denotes atom http://purl.obolibrary.org/obo/CHEBI_33250
T251 43516-43520 Chemical denotes atom http://purl.obolibrary.org/obo/CHEBI_33250
T252 43557-43565 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T253 43687-43695 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T254 43775-43780 Chemical denotes probe http://purl.obolibrary.org/obo/CHEBI_50406
T255 43876-43884 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T256 44010-44018 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T257 44091-44099 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T258 44211-44218 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T259 44219-44227 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T260 44229-44233 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T262 44284-44295 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T263 44284-44289 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T264 44290-44295 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T265 44384-44392 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T266 44400-44409 Chemical denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T267 44414-44423 Chemical denotes aspartate http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314
T270 44451-44459 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T271 44467-44475 Chemical denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T274 44480-44486 Chemical denotes lysine http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094
T276 44509-44513 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T278 44546-44555 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T279 44651-44655 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T281 44878-44882 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T283 45419-45428 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T68162 49981-49988 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T88883 50048-50056 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T41356 50324-50334 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T93398 50339-50352 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T86712 51617-51630 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T55569 52410-52416 Chemical denotes PB1-F2 http://purl.obolibrary.org/obo/CHEBI_82128
T44580 52414-52416 Chemical denotes F2 http://purl.obolibrary.org/obo/CHEBI_30236
T20563 52432-52439 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T43615 52594-52600 Chemical denotes PB1-F2 http://purl.obolibrary.org/obo/CHEBI_82128
T17896 52598-52600 Chemical denotes F2 http://purl.obolibrary.org/obo/CHEBI_30236
T73245 52727-52740 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T46751 52856-52869 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T64351 52870-52878 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T89809 52896-52905 Chemical denotes defensins http://purl.obolibrary.org/obo/CHEBI_82761
T74619 53128-53136 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T25381 55271-55278 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T42671 55412-55419 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T98566 55420-55427 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T99137 55463-55471 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 290-300 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T2 351-367 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T3 509-519 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T4 659-672 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T5 702-718 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T6 1362-1372 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T7 1422-1438 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T8 1660-1670 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T9 1902-1918 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T10 2028-2041 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T11 2161-2176 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T12 8017-8049 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T13 8051-8054 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T14 8523-8532 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T15 8523-8532 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T16 9001-9017 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T17 10431-10446 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T18 10451-10464 http://purl.obolibrary.org/obo/GO_0006412 denotes translational
T19 10563-10576 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T20 11465-11480 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T21 11718-11726 http://purl.obolibrary.org/obo/GO_0007612 denotes learning
T22 12081-12084 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T23 12109-12112 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T24 12131-12134 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T25 12351-12364 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T26 20658-20670 http://purl.obolibrary.org/obo/GO_0008228 denotes opsonization
T27 20944-20956 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T28 21538-21548 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T29 21878-21915 http://purl.obolibrary.org/obo/GO_0003968 denotes RNA-dependent RNA polymerase activity
T30 22343-22353 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T31 23446-23456 http://purl.obolibrary.org/obo/GO_0004175 denotes Proteinase
T32 24775-24801 http://purl.obolibrary.org/obo/GO_0002520 denotes immune system, development
T33 25130-25136 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T34 25340-25362 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T35 25340-25362 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T36 26100-26110 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T37 26704-26707 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T38 26714-26717 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T39 26783-26793 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T40 27146-27149 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T41 27188-27191 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T42 27274-27277 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T43 27378-27394 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T44 27848-27858 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T45 28502-28512 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T46 29630-29646 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T47 35979-35992 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T48 36185-36194 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T49 36295-36310 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T50 36459-36476 http://purl.obolibrary.org/obo/GO_0006952 denotes defense responses
T51 36616-36629 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T52 38809-38822 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T53 39012-39025 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T54 39417-39433 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T55 40189-40202 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T56 43106-43114 http://purl.obolibrary.org/obo/GO_0007610 denotes behavior

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-164 Sentence denotes Design of a Novel Multi Epitope-Based Vaccine for Pandemic Coronavirus Disease (COVID-19) by Vaccinomics and Probable Prevention Strategy against Avenging Zoonotics
T2 166-176 Sentence denotes Highlights
T3 177-272 Sentence denotes • A novel multi-epitope based chimeric vaccine is designed for coronavirus disease (COVID-19).
T4 273-380 Sentence denotes • Nsp8, 3C-like proteinase, and spike glycoprotein are potential targets for immune responses to COVID-19.
T5 381-445 Sentence denotes • Two epitopes: DRDAAMQRK and QARSEDKRA are predicted for Nsp8.
T6 446-520 Sentence denotes • EDMLNPNYEDL and EFTPFDVVR epitopes are revealed for 3C-like proteinase.
T7 521-588 Sentence denotes • Spike glycoprotein harbored one potential “VNNSYECDIPI” epitope.
T8 589-683 Sentence denotes • A chimeric construct of the epitopes has high binding affinity for innate immune receptors.
T9 684-745 Sentence denotes • Robust primary immune responses to the contrast are found.
T10 746-813 Sentence denotes • The construct-immune receptors complexes are dynamically stable.
T11 814-898 Sentence denotes • Vigorous molecular mechanics and solvation energy were observed in the complexes.
T12 900-908 Sentence denotes Abstract
T13 909-1109 Sentence denotes The emergence and rapid expansion of the coronavirus disease (COVID-19) require the development of effective countermeasures especially a vaccine to provide active acquired immunity against the virus.
T14 1110-1306 Sentence denotes This study presented a comprehensive vaccinomics approach applied to the complete protein data published so far in the National Center for Biotechnological Information (NCBI) coronavirus data hub.
T15 1307-1451 Sentence denotes We identified non-structural protein 8 (Nsp8), 3C-like proteinase, and spike glycoprotein as potential targets for immune responses to COVID-19.
T16 1452-1555 Sentence denotes Epitopes prediction illustrated both B-cell and T-cell epitopes associated with the mentioned proteins.
T17 1556-1827 Sentence denotes The shared B and T-cell epitopes: DRDAAMQRK and QARSEDKRA of Nsp8, EDMLNPNYEDL and EFTPFDVVR of 3C-like proteinase, and VNNSYECDIPI of the spike glycoprotein are regions of high potential interest and have a high likelihood of being recognized by the human immune system.
T18 1828-1954 Sentence denotes The vaccine construct of the epitopes shows stimulation of robust primary immune responses and high level of interferon gamma.
T19 1955-2112 Sentence denotes Also, the construct has the best conformation with respect to the tested innate immune receptors involving vigorous molecular mechanics and solvation energy.
T20 2113-2348 Sentence denotes Designing of vaccination strategies that target immune response focusing on these conserved epitopes could generate immunity that not only provide cross protection across Betacoronaviruses but additionally resistant to virus evolution.
T21 2350-2368 Sentence denotes Graphical abstract
T22 2370-2385 Sentence denotes 1 Introduction
T23 2386-2541 Sentence denotes A recent outbreak of pneumonia in Wuhan, China, is associated with Betacoronavirus of group 2B from family Coronaviridae and the order Nidovirales [1] [2].
T24 2542-2610 Sentence denotes The viruses are positive-sense RNA, enveloped and non-segmented [2].
T25 2611-2772 Sentence denotes This coronavirus disease (COVID-19) is known as a third human zoonosis of the 21st century and is caused by a new strain not previously identified in humans [1].
T26 2773-3121 Sentence denotes The coronaviruses causing minor infections of the respiratory tract in humans are NL63, OC43, hCoV-229E, and HKU1 while, the lethal coronavirus infections that emerged in this century are the Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV) and the recent SARS-CoV 2 or COVID-19 [2].
T27 3122-3278 Sentence denotes The source of the COVID-19 is still not confirmed but some evidence suggests that the source may be in the seafood market of Huanan in Wuhan, China [3] [4].
T28 3279-3521 Sentence denotes The Center for Disease Control and Prevention (CDC) reported that the recent COVID-19 is caused by Betacoronavirus just like the previous two outbreaks of coronaviruses; MERS and SARS, the source of which is camels and bats, respectively [5].
T29 3522-3643 Sentence denotes The first transmission of CoV from animals to humans was notified in 2002 causing SARS-CoV with a 10% mortality rate [6].
T30 3644-3917 Sentence denotes It was suggested that the virus needs some intermediate reservoir to infect humans efficiently as confirmed later by a thorough investigation revealing palm civets and raccoon dogs of the wet market carried SARS-CoV viral RNA and might act like intermediate reservoirs [3].
T31 3918-4051 Sentence denotes The COVID-19 RNA virus carries a high mutation rate and ability to transfer from person to person as compared to other coronaviruses.
T32 4052-4279 Sentence denotes According to the World Health Organization (WHO), till 23rd February 2020, the COVID-19 affected a total of 78,811 individuals across globally of which, 77,042 were reported in China while 1769 were reported in other countries.
T33 4280-4370 Sentence denotes The death toll in China is 2445 and 17 deaths have been reported in the rest of the world.
T34 4371-4611 Sentence denotes According to the reports till 2nd January 2020, 41 patients have been admitted to the hospital of which most of the patients were men and 66% of them had exposure to the Huanan seafood market and the median age of patients was 49 years [2].
T35 4612-4719 Sentence denotes The health-care workers are also diagnosed with the infection including those working in similar wards [6].
T36 4720-4802 Sentence denotes The time taken by COVID-19 to infect other individuals is similar to that of SARS.
T37 4803-4936 Sentence denotes It is estimated that on average each infected person infects 2-3 persons and this occurrence increases two-folds, every 6.4 days [7].
T38 4937-5028 Sentence denotes It was observed that people with mild infection are more actively spread the infection [8].
T39 5029-5194 Sentence denotes Due to critical nature of the outbreak, the virus was sequenced on urgent basis and the first sequence was available on 10th January, 2020 online at virological.org.
T40 5195-5280 Sentence denotes It was noted that COVID-19 has much resemblance to SARS-CoV at the genomic level [4].
T41 5281-5388 Sentence denotes Symptoms of COVID-19 include fever, dry cough, shortness of breath and dyspnea, sore throat and leukopenia.
T42 5389-5515 Sentence denotes To date no vaccine COVID-19 is available and is need of an hour to develop a vaccine to prevent further spread of the disease.
T43 5516-5706 Sentence denotes To this end, immuno-informatics can be applied to a complete protein data set of the virus for deep antigen analysis and thus can save time and cost for designing a vaccine against COVID-19.
T44 5707-5829 Sentence denotes This will ease the early development of a vaccine and proposed design can be subjected immediately to experimental trials.
T45 5831-5854 Sentence denotes 2 Material and Methods
T46 5855-5973 Sentence denotes The stepwise flow of the methodology followed to design a vaccine against COVID-19 is illustrated in Figure 1 Fig. 1 .
T47 5974-6050 Sentence denotes Fig. 1 Designed workflow for in silico vaccine engineering against COVID-19.
T48 6052-6112 Sentence denotes 2.1 Prioritization of Potential COVID-19 Vaccine Candidates
T49 6113-6497 Sentence denotes The complete dataset of proteins available in (NCBI) [9] coronavirus data hub (https://www.ncbi.nlm.nih.gov/labs/virus/vssi/#/virus?SeqType_s=Nucleotide&VirusLineage_ss=Wuhan%20seafood%20market%20pneumonia%20virus,%20taxid:2697049&utm_campaign=wuhan_nCoV&utm_source=insights&utm_medium=referral) was retrieved and subjected to screening phase to identify potential vaccine candidates.
T50 6498-6615 Sentence denotes First, host non-similar proteins of the pathogen were filtered that show no homology to the human host (taxonomic id:
T51 6616-6622 Sentence denotes 9606).
T52 6623-6732 Sentence denotes Proteins having sequence E score < 1.0 E−5, bit score > 100, and sequence identity ≤ 30 % were selected [10].
T53 6733-6948 Sentence denotes Again, a BLASTp search against the Mouse (Mus musculus, taxonomy id: 10090) was performed using host non-similar proteins keeping the input parameters E score cut-off 0.005, bit score > 100, and identity < 30% [11].
T54 6949-7097 Sentence denotes The screened mouse non-similar proteins were then subjected to TMHMM 2.0 [12] and HMMTOP 2.0 [13] for observing the number of transmembrane helices.
T55 7098-7293 Sentence denotes Proteins having less than two transmembrane helices were subjected to SPAAN [14] for predicting the adhesive proteins as they have the potential to facilitate attachment to the host tissues [15].
T56 7294-7499 Sentence denotes Selected vaccine candidates were then used in BLASTp tool to align the selected adhesive protein candidates with the probiotic bacteria proteome including three Lactobacillus species: L. rhamnosus (tax id:
T57 7500-7529 Sentence denotes 47715), L. johnsonii (tax id:
T58 7530-7570 Sentence denotes 33959), and Lactobacillus casei (tax id:
T59 7571-7640 Sentence denotes 1582) to avoid accidental inhibition of the useful gut bacteria [11].
T60 7642-7676 Sentence denotes 2.2 B and T-cell Epitopes Mapping
T61 7677-7819 Sentence denotes Selected vaccine candidates were then subjected to the immune epitope database (IEDB) Bepipred Linear Epitope Prediction 2.0 [16], [17], [18].
T62 7820-8084 Sentence denotes The threshold of 0.5 was used for the prediction of linear B-cells epitopes which were then utilized in T-cell epitopes mapping to identify subsequences with the potential to bind reference set of major histocompatibility complex (MHC) class I and II alleles [16].
T63 8085-8217 Sentence denotes Epitopes were ranked according to their percentile score, the ones with the low percentile were considered as high affinity binders.
T64 8218-8361 Sentence denotes The selected B-cell derived T-cell epitopes were then subjected to MHCPred 2.0 [19] analysis for interpreting their binding affinity potential.
T65 8362-8433 Sentence denotes The cut-off criterion was set to IC50 values < 100 nM for DRB*0101[20].
T66 8434-8589 Sentence denotes Following this, the VirulentPred [21] and VaxiJen 2.0 [22] were utilized to validate the virulence and antigenicity of the selected epitopes, respectively.
T67 8590-8652 Sentence denotes AllerTOP 2.0 [23] was applied to remove the allergic epitopes.
T68 8653-8795 Sentence denotes CLC main workbench was employed to check the conservation of non-allergic epitopes required for designing an effective broad-spectrum vaccine.
T69 8797-8862 Sentence denotes 2.3 Construction of Multi-Epitopes Peptide (MEP) and Adjuvanting
T70 8863-9023 Sentence denotes Overlapping immunodominant epitopes were used to construct a multi-epitope peptide (MEP) which is considered a promising strategy to stop viral infections [24].
T71 9024-9180 Sentence denotes One of the key issues with the design of peptide vaccine is its weak immunogenicity that can be resolved by designing a MEP with appropriate adjuvants [25].
T72 9181-9281 Sentence denotes In the current study, MEP was designed using AAY linkers to combine screened multiple epitopes [26].
T73 9282-9453 Sentence denotes To the N-terminal of MEP, an adjuvant in the form of B subunit of cholera toxin was linked to the MEP thus creating a multi-epitope peptide vaccine construct (MEPVC) [27].
T74 9454-9605 Sentence denotes The tertiary structure of the MEPVC was created through a software called 3Dpro of SCRATCH protein predictor [28], I-tasser [29], and Swiss-Model [30].
T75 9606-9718 Sentence denotes The best model was further loop modelled using GalaxyLoop [31] and refined using GalaxyRefine [32] of GalaxyWeb.
T76 9719-9833 Sentence denotes To improve the construct's stability, disulfide bonds were introduced in the structure [33] using Design 2.0 [34].
T77 9834-10071 Sentence denotes The sequence of the MEPVC was translated in reverse and then optimized for codon usage according to the Escherichia coli, which will end up in the increased expression of the MEPVC sequence cloned in the mentioned expression system [35].
T78 10072-10161 Sentence denotes The entire activity was accomplished using Java Codon Adaptation Tool (JCat) server [36].
T79 10162-10293 Sentence denotes In order to assess the expression of sequence that have been cloned, the GC content and codon adaptation index (CAI) were measured.
T80 10294-10483 Sentence denotes The value of 1 CAI is contemplated ideal [37,38] whereas the appropriate GC content should be fluctuated between 30-70% due to favorable transcriptional and translational efficiencies [27].
T81 10484-10682 Sentence denotes There were other input factors carefully calculated to prevent rho-independent transcription termination, the binding sites of the prokaryotic ribosome, and the cleavage sites of restriction enzyme.
T82 10683-10850 Sentence denotes As the final step of this phase, the cloning of the engineered construct was carried out into pET-28a (+) expression vector using SnapGene (https://www.snapgene.com/).
T83 10852-10898 Sentence denotes 2.4 Physicochemical Characterization of MEPVC
T84 10899-11216 Sentence denotes ProtParam tool [39] was applied for analyzing the physical and chemical properties of MEPVC such as amino acid composition, estimated half-life, instability index, extinction coefficient, theoretical pl, atomic composition, molecular weight, and grand average of hydropathicity (GRAVY) to assist experimental studies.
T85 11217-11388 Sentence denotes Instability index is one of the key parameters that is significantly considered as it helps in discarding the unstable protein candidates (protein instability index > 40).
T86 11390-11418 Sentence denotes 2.5 MEPVC Immune Simulation
T87 11419-11572 Sentence denotes In this step, the vaccine construct underwent immune response profiling and immunogenicity classification, which was done using the C-ImmSim server [40].
T88 11573-11686 Sentence denotes In order to predict the immune epitopes, a position-specific scoring matrix (PSSM) employed by C-ImmSim was used.
T89 11687-11783 Sentence denotes Whereas, the different machine learning procedures were used to forecast the immune connections.
T90 11784-11927 Sentence denotes This server is concurrently used to execute an immune simulation for 3 compartments such as bone marrow, tertiary lymph nodes, and thymus [41].
T91 11928-12203 Sentence denotes Default simulation parameters were used which are as follows: random seed (12345), simulation steps (100), simulation volume (10), host HLA selection (A MHC class I A0101 allele, B MHC class I B0702, DR MHC class II DRB1_0101 allele), and time step of injection was set to 1.
T92 12205-12238 Sentence denotes 2.6 MEPVC Docking and Refinement
T93 12239-12374 Sentence denotes The technique of molecular docking was utilized to predict conformation of the MEPVC with respect to a suitable innate immune receptor.
T94 12375-12505 Sentence denotes This analysis plays a significant role to determine the high-affinity contacts amid the vaccine construct and the immune receptor.
T95 12506-12517 Sentence denotes The PDB ID:
T96 12518-12539 Sentence denotes 4G8A and TLR3 PDB ID:
T97 12540-12629 Sentence denotes 2A0Z were retrieved from the Protein Data Bank (PDB) for the TLR4 and TLR3, respectively.
T98 12630-12775 Sentence denotes Blind docking employed to calculate the regular pose of the vaccine construct with the mentioned receptors using an online PATCHDOCK server [42].
T99 12776-12897 Sentence denotes The resulting structures were further refined using the Fast Interaction Refinement in Molecular Docking (FireDock) [43].
T100 12898-13173 Sentence denotes The top ranked complex with the minimum global energy was selected and used to analyse the binding pose and intermolecular connections using UCSF Chimera 1.13.1 [44], Discovery Studio (DS) Visualizer 17.2.0 [45].16349, and Visual Molecular Dynamics (VMD) 1.9.3 software [46].
T101 13175-13224 Sentence denotes 2.7 Simulations of MEPVC-Innate Immune Receptors
T102 13225-13372 Sentence denotes In order to gain insights into the dynamics of the vaccine construct with the receptors, molecular dynamics (MD) simulations have been carried out.
T103 13373-13537 Sentence denotes The simulation analysis was also important to validate the exposure of epitopes towards the host structure for identification and handling of a substantial outcome.
T104 13538-13722 Sentence denotes The MD simulations took place in three different phases: system preparation, pre-processing and production [47] with an Assistant model building with Energy Refinement (AMBER) 16 [48].
T105 13723-13834 Sentence denotes The antechamber program [49] was used to build the libraries and parameters for the TLR4 and vaccine construct.
T106 13835-13909 Sentence denotes The TIP3P solvation box (size 12 Å) was inserted to solvate the construct.
T107 13910-14058 Sentence denotes To study the intermolecular interactions, force field, ff14SB [50] was used whereas, the system was neutralized by the addition of Na+ counter ions.
T108 14059-14155 Sentence denotes In the second phase of MD simulations, the energy minimization of the complexes was carried out.
T109 14156-14599 Sentence denotes Each complex was minimized using the following steps: the energy minimization of hydrogen atoms (500 cycles), energy minimization of water box (1000 cycles, control of 200 kcal/mol – Å2 on rest of the system), minimization of the whole atoms of the system (1000 cycles with the restraint of 5 kcal/mol –Å2 on Cα atoms), and the rest of the system was subjected to non-heavy atoms minimization with 300 cycles and restraint of 100 kcal/mol –Å2.
T110 14600-14750 Sentence denotes In the next step, the system was gradually heated from 0 K to 300 K with the time step of 2 femtoseconds and restraints of 5 kcal/mol –Å2 on Cα atoms.
T111 14751-14865 Sentence denotes In order to sustain the temperature of the system, Langevin dynamics [51] with the gamma value of 1.0 was castoff.
T112 14866-14967 Sentence denotes The SHAKE algorithm [52] was used to put constraints on the hydrogen bonds of the system for heating.
T113 14968-15172 Sentence denotes In the next step, systems were equilibrated for 100 ps with a time step of 2 fs followed by pressure equilibrium, which was attained using the NPT ensemble with restraints of 5 kcal/mol – Å 2 on Cα atoms.
T114 15173-15262 Sentence denotes The same step was extended for 50 ps with the 1 scale down on restraints on carbon atoms.
T115 15263-15421 Sentence denotes However, the step of system equilibration was carried out for a time scale of 1 nanosecond followed by the production run of 100 ns with a time scale of 2 fs.
T116 15422-15530 Sentence denotes For the production run, the Berendsen algorithm [53] with the NVT ensemble cast off with a cut-off of 8.0 Ǻ.
T117 15531-15649 Sentence denotes Simulation trajectories were calculated to investigate the strength of a complex via the CPPTRAJ module [54] of AMBER.
T118 15650-15769 Sentence denotes However, the visualization of simulation trajectories was done with UCSF Chimera [55], DS Visualizer [45] and VMD [46].
T119 15771-15811 Sentence denotes 2.8 Estimation of Binding Free Energies
T120 15812-15978 Sentence denotes In order to estimate the MMPBSA binding free energies for the receptors and multi-epitope peptide vaccine construct, the MMPBSA.py module [56] of AMBER16 was castoff.
T121 15979-16094 Sentence denotes The program generated the input files for the complex, receptor and MEPVC molecule using the ante-MMPBSA.py module.
T122 16095-16232 Sentence denotes To compute the variance between the solvated and un-solvated phases, 100 frames of simulation trajectories were picked and analyzed [57].
T123 16233-16375 Sentence denotes For the precise values of binding free energies, the two different conformations were matched to the binding energies of significant residues.
T124 16376-16704 Sentence denotes To estimate the free binding energy of the anticipated complex, ΔGbind, solv was resolved using the three equations (Eqn 1,Eqn 2,Eqn 3 ) given below:(1) ΔGbind,solv=ΔGbind,vaccum+ΔGsolv,complex−ΔGsolv,ligand−ΔGsolv,complex (2) ΔGsolv=ΔGelectrostatic(ϵ80−1)+ΔGhydrophobic (3) ΔGvaccum=ΔEmolecularmechanics−−T.ΔGnormalmodeanalysis
T125 16705-16823 Sentence denotes The net free binding energy was then decomposition into each residue to highlight the interacting and stable residues.
T126 16825-16830 Sentence denotes 3 3.
T127 16831-16854 Sentence denotes Results and Discussions
T128 16856-16891 Sentence denotes 3.1 Retrieval of protein sequences
T129 16892-17048 Sentence denotes The NCBI most recently dedicated a coronavirus disease data hub containing all nucleotide and protein sequences information published from across the world.
T130 17049-17241 Sentence denotes In this study, we aimed at in silico prioritization potential vaccine candidates and designing a chimeric peptide vaccine for COVID-19 based on all available protein sequences in the data hub.
T131 17242-17391 Sentence denotes Several bioinformatic and immunoinformatics techniques are employed with the aim to assist experimentalists in vaccine development against the virus.
T132 17393-17444 Sentence denotes 3.2 Identification of Potential Vaccine Candidates
T133 17445-17772 Sentence denotes Prioritization of potential vaccine candidates could help in minimizing time, labor cost and resources for developing and optimizing the success of getting an effective vaccine against the pathogen. In total, 193 protein entries were retrieved (S-Table 1 ) and analyzed first for sequence homology with the human host proteome.
T134 17773-17953 Sentence denotes This was significant to evaluate as homology between virus protein (s) to be used in vaccine designing and the host is likely to cause strong autoimmune reactions in the host [58].
T135 17954-18135 Sentence denotes This check identified two proteins: (orf1a polyprotein (Accession id, YP_009725295) and nsp3 (Accession id, YP_009725299) as host homologous thus discarded from further evaluations.
T136 18136-18316 Sentence denotes Experimental studies of the human vaccines are usually done in mice because of the many practical advantages they provide compared to vaccine research in higher animal models [22].
T137 18317-18455 Sentence denotes The appropriateness of mice as an animal model for vaccine research is defined by its ability to reproduce relevant human physiology [59].
T138 18456-18643 Sentence denotes Considering this, a homology check was devoted to the pipeline and applied to the filtered human non-similar proteins (191 in number) to ensure the selection of non-similar mice proteins.
T139 18644-18953 Sentence denotes This assessment resultant into shortlisting of Orf1ab polyprotein (Accession ids, QHQ82463, QHD43415, QHR63279, QHR63259, QHQ71962, QHO62106, QHQ71972, QHR63249, QHO60603, QHO62111, QHN73794, QHR84448, QHR63269, QHN73809, QHR63289, and QHO62876) and nsp3 (Accession id, YP_009724389) as mice similar proteins.
T140 18954-19188 Sentence denotes The mice non-similar proteins will aid in discouraging false positive results during in vivo experimentations and accurate interpretation of immune protective efficiency of the prioritized vaccine candidates against the virus [22,60].
T141 19189-19293 Sentence denotes Next, enumeration of transmembrane helices in the pooled 174 mice non-similar proteins was accomplished.
T142 19294-19435 Sentence denotes This transmembrane topology characterization is deemed vital in relatedness to the afterward experimental expression studies of the proteins.
T143 19436-19654 Sentence denotes Protein with transmembrane helices less than 2 in numbers are often considered as best vaccine candidates as multiple helices make recombinant proteins purification and expression difficult in vaccine development [20].
T144 19655-19719 Sentence denotes This result 33 proteins spanning across five types, and include:
T145 19720-20324 Sentence denotes Orf3a polyprotein (Accession id, QHQ71974, QHR84450, QHD43417, QHQ71964, QHQ82465, QHO60595, YP_009724391, QHN73811, QHN73796, QHO62878), nsp4 (Accession id, YP_009725300), membrane glycoprotein (Accession id, QHD43419, QHQ71966, QHQ71976, QHQ82467, YP_009724393, QHO60597, QHN73813, QHN73798, QHO62880, QHR84452), membrane protein (Accession id, QHR63283, QHR63263, QHR63273, QHR63293, QHR63253), matrix protein (Accession id, QHO62109, QHO62114), and nonstructural protein NS3 (Accession id, QHR63251, QHR63281, QHR63261, QHR63271, QHR63291) containing multiple helices therefore not proceeded further.
T146 20325-20490 Sentence denotes The creation of adhesin-based vaccines is considered an attractive and effective strategy and is being explored as a solution to number of infectious pathogens [61].
T147 20491-20587 Sentence denotes The idea behind exploiting adhesin for a vaccine is based on the promising preclinical findings.
T148 20588-21065 Sentence denotes The aim is to confer protective immunity via two main mechanisms: (i) opsonization driven by opsonising antibodies that is capable of binding the target antigen as an immunological tag leading to activation of other components of the host immune system for enhance recognition of the pathogen and subsequent complement system activity and virus killing by phagocytosis, (ii) neutralization driven by adhesin-specific antibodies that block virus binding ability to host tissues.
T149 21066-21271 Sentence denotes The adhesion probability computation revealed 26 protein to have adhesion probability value greater than a threshold as tabulated in S-Table 2 and can be ideal putative vaccine candidates against COVID-19.
T150 21272-21488 Sentence denotes The adhesin probability of protein ranges from 0.593 to 0.796 (mean, 0.645).Antigenicity of proteins was predicted to reflect their ability of binding to products of adaptive immunity: antibodies or T-cell receptors.
T151 21489-21681 Sentence denotes In total, 7 proteins: nsp8, nsp9, nsp10, 3C-like proteinase, spike glycoprotein, surface glycoprotein, and ORF1ab polyprotein were recognized as antigenic and scored higher than the threshold.
T152 21682-21980 Sentence denotes Coronavirus nsp8 suggested having diverse activities, including template-dependent RNA polymerase activities, canonical RNA-dependent RNA polymerases, cofactor function of nsp8 for nsp12-mediated RNA-dependent RNA polymerase activity, and metal ion-dependent RNA 3′ polyadenylation activities [62].
T153 21981-22098 Sentence denotes Nsp9 is a non-structural protein 9, key to coronavirus replication and is a single-stranded RNA-binding protein [63].
T154 22099-22183 Sentence denotes Nsp10 is a critical cofactor that switches on multiple enzymes in replication cycle.
T155 22184-22483 Sentence denotes It is known to interact with nsp14 and nsp16 subunits activating their respective 3′-5′ exoribonuclease and 2′-O-methyltransferase functions [64]. The 3C-like proteinase is main cysteine protease and is nonstructural protein number 5 (nsp5) and essential in mediating cleavage of nsp4 to nsp16 [65].
T156 22484-22654 Sentence denotes The trimeric transmembrane coronavirus spike glycoprotein initiates infectious cycle by binding to a specific receptor on the host membrane followed by viral fusion [66].
T157 22655-22781 Sentence denotes The surface glycoprotein was analyzed to be different in a sequence patch (Leu3-Phe11) at the start of the spike glycoprotein.
T158 22782-23079 Sentence denotes The ORF1ab is replicase polyprotein cleaved by papain-like protease and 3C-like protease at specific cleavage sites to yield 15 to 16 non-structural proteins (nsps) [67].  The final numbers of potential vaccine candidates obtained in this step by step subtraction phase are presented in Figure 2 .
T159 23080-23205 Sentence denotes Table 1 The final set of selected B-cell derived T-cell epitopes for the potential three vaccine candidates against COVID-19.
T160 23206-23354 Sentence denotes Protein Common B and T-cell Epitopes Antigenicity (cut off score, 0.4) MHCphred (IC50 score, 100 nM) Allergenicity Virulentpred (cut off score, 0.5)
T161 23355-23402 Sentence denotes Nsp8 DRDAAMQRK 0.8641 35.81 non-allergen 1.0606
T162 23403-23445 Sentence denotes QARSEDKRA 0.5770 24.15 non-allergen 1.0606
T163 23446-23501 Sentence denotes Proteinase EDMLNPNYEDL 1.0913 21.68 non-allergen 1.0600
T164 23502-23543 Sentence denotes EFTPFDVVR 1.6049 5.07 non-allergen 1.0604
T165 23544-23607 Sentence denotes Spike Glycoprotein VNNSYECDIPI 1.0996 23.93 non-allergen 1.0593
T166 23608-23690 Sentence denotes Table 2 Top 10 refined models of the MEPVC along with the initial input structure.
T167 23691-23765 Sentence denotes Model RMSD MolProbity Clash score Poor rotamers Rama favored GALAXY energy
T168 23766-23808 Sentence denotes Initial 0.000 3.312 95.9 3.8 93.6 20995.70
T169 23809-23850 Sentence denotes MODEL 1 1.734 1.134 1.2 0.0 95.7 -3784.31
T170 23851-23892 Sentence denotes MODEL 2 1.920 1.444 2.4 0.0 93.6 -3750.72
T171 23893-23934 Sentence denotes MODEL 3 1.766 0.997 0.6 0.0 95.7 -3743.81
T172 23935-23976 Sentence denotes MODEL 4 1.667 0.997 0.6 0.0 95.7 -3739.43
T173 23977-24018 Sentence denotes MODEL 5 2.611 1.187 0.9 1.3 95.2 -3731.44
T174 24019-24060 Sentence denotes MODEL 6 1.782 1.187 0.9 1.3 95.2 -3724.93
T175 24061-24102 Sentence denotes MODEL 7 2.907 1.144 1.5 0.0 96.3 -3722.41
T176 24103-24144 Sentence denotes MODEL 8 1.999 1.459 3.0 0.6 94.7 -3718.59
T177 24145-24186 Sentence denotes MODEL 9 3.194 1.192 1.8 0.0 96.3 -3715.99
T178 24187-24229 Sentence denotes MODEL 10 2.235 1.310 2.7 0.6 96.3 -3713.14
T179 24230-24355 Sentence denotes Fig. 2 The final set of potential vaccine candidates filtered through several in silico checks presented as interactive Venn.
T180 24356-24588 Sentence denotes The total number of proteins (TPs), filtered to 191 host non-homologous proteins (HNHPs), 174 mouse non-similar proteins (MNSPs), 26 adhesive proteins (APs), 7 antigenic proteins and finally to 3 potential vaccine candidates (PVCs).
T181 24590-24624 Sentence denotes 3.3 B and T-cell Epitopes Mapping
T182 24625-24866 Sentence denotes Identification of epitopes in given antigens is vital for a number of practical reasons, including understanding etiology of a disease, monitoring of immune system, development of diagnostic assays, and epitope-based vaccines designing [68].
T183 24867-25011 Sentence denotes From vaccine designing point of view, host adaptive immunity is highly specific and is able to recognize and destroy the invading pathogen [69].
T184 25012-25223 Sentence denotes Additionally, adaptive immunity is able to remember the pathogens, creating long-lasting pathogen-specific protective memory enabling stronger attacks against the pathogen reencountered on successive times [70].
T185 25224-25293 Sentence denotes This arm of host immune system is driven by lymphocytes of two types:
T186 25294-25382 Sentence denotes B and T-cells responsible for the humoral and cell-mediated immunity, respectively [71].
T187 25383-25450 Sentence denotes Both cells recognize pathogen molecular components called antigens.
T188 25451-25537 Sentence denotes The antigens interact with specific receptors present on the surface of B and T-cells.
T189 25538-25691 Sentence denotes The activation of both these cells required antigen recognition by these receptors, in addition, to the second activation signals from the innate system.
T190 25692-25791 Sentence denotes The vaccine candidates prioritized in the first phase were deeply investigated for B-cell epitopes.
T191 25792-25987 Sentence denotes Different lengths of linear B-cell epitopes were predicted for each protein and only recurrent epitopes simultaneously predicted by different servers were selected for chimeric vaccine designing.
T192 25988-26237 Sentence denotes The B-cell epitopes predicted for the vaccine candidates were in the following order: nine for Nsp8 and 3C-like proteinase, five for Nsp9, eight for Nsp10, 34 for spike glycoprotein and surface glycoprotein, and four for ORF1ab polyprotein| partial.
T193 26238-26383 Sentence denotes These B-cells epitopes are recognized as solvent-exposed antigens through B-cell receptors (BCR) and upon activation, B-cells secrete antibodies.
T194 26384-26505 Sentence denotes Antibodies have different functions including neutralizing pathogens, toxins and labeling pathogens for destruction [72].
T195 26506-26617 Sentence denotes The proteins were also analyzed for T-cell epitopes through very stringent criteria of p-value less than 0.005.
T196 26618-26721 Sentence denotes The epitopes were of different lengths and interact with several different alleles of MHC-I and MHC-II.
T197 26722-26952 Sentence denotes For Nsp8, 94 epitopes predicted whereas Nsp9, Nsp10, 3C-like proteinase, spike glycoprotein, surface glycoprotein and ORF1ab polyprotein| partial protein were mapped for 61, 76, 153, 657, 651, and 44, respectively T-cell epitopes.
T198 26953-27165 Sentence denotes These epitopes are presented on the surface through specific receptors known as T-cell receptor (TCR) allowing recognition of these antigens when displayed by antigen-presenting cells bound to MHC molecules [73].
T199 27166-27316 Sentence denotes Epitopes presented by MHC I are recognized by CD8 (cytotoxic T lymphocytes) [74] whereas those presented by MHC II are recognized by CD4 T-cells [75].
T200 27317-27416 Sentence denotes The CD4 T-cells later become helper T-cells that amplify the immune responses against the pathogen.
T201 27417-27629 Sentence denotes Comparative analysis of the predicted epitopes was further carried out to select epitopes that are common to B-cell, CD4 T-cell and CD8 T-cell alleles in order to design a specific, effective, and strong vaccine.
T202 27630-28090 Sentence denotes On this basis, three epitopes from Nsp8 (DRDAAMQRK, QARSEDKRA, EQAVANGDSEV), none for Nsp9 and ORF1ab polyprotein| partial protein, four for Nsp10 (GCSCDQLREP, YLASGGQPIT, YLASGGQPI, TVTPEANMDQESFG), three for 3C-like proteinase (EDMLNPNYEDL, KYNYEPLTQDHV, EFTPFDVVR), five for spike glycoprotein (RVYSTGSNVFQ, VNNSYECDIPI, LADAGFIKQYGDCLG, GQSKRVDFC, RNFYEPQIITTD) and surface glycoprotein (RVYSTGSNVFQ, VNNSYECDIPI, LADAGFIKQYGDCLG, GQSKRVDFC, RNFYEPQIITTD).
T203 28091-28212 Sentence denotes The epitopes were then reevaluated in antigenicity check to make sure their binding potential of binding to immune cells.
T204 28213-28396 Sentence denotes For Nsp8, DRDAAMQRK and QARSEDKRA were found antigenic with score higher than the default threshold of 0.4 whereas the third epitope EQAVANGDSEV was found non-antigenic hence removed.
T205 28397-28482 Sentence denotes All the four epitopes of Nsp9 revealed non-antigenic therefore not processed further.
T206 28483-28643 Sentence denotes In case of 3C-like proteinase, KYNYEPLTQDHV was found non-antigenic whereas EDMLNPNYEDL and EFTPFDVVR were antigenic therefore considered in afterward analysis.
T207 28644-28802 Sentence denotes The spike glycoprotein contains epitopes VNNSYECDIPI, and RNFYEPQIITTD as antigenic whereas none of the surface glycoprotein provided epitopes were antigenic.
T208 28803-29015 Sentence denotes Following, the affinity of the filtered antigenic epitopes for the most prevalent DRB*0101 allele in humans was evaluated through IC50 value and those with value < 100 nM were classified as high affinity binders.
T209 29016-29118 Sentence denotes All the pooled antigenic epitopes were found to have great ability of binding to the mentioned allele.
T210 29119-29255 Sentence denotes Similarly, these epitopes were evaluated in allergenicity and virulent potential check and only virulent and non-allergen were selected.
T211 29256-29363 Sentence denotes Virulent check was significant in ensuring selection of epitopes mediating infectious pathways in the host.
T212 29364-29447 Sentence denotes The final selected epitopes that cleared all these checks are tabulated in Table 1.
T213 29449-29475 Sentence denotes 3.4 Construction of MEPVC
T214 29476-29556 Sentence denotes A MEP was constructed first comprising epitopes finalized in the previous phase.
T215 29557-29652 Sentence denotes MEP based vaccines are considered an ideal approach to prevent and treat viral infections [24].
T216 29653-29828 Sentence denotes The epitopes shown in Table 1 were linked to each other through flexible AAY linkers as such it allows efficient separation required for the effective working of each epitope.
T217 29829-29934 Sentence denotes Once the MEP was designed, to its N-terminus an adjuvant of Cholera toxin subunit B (CTB) was added [76].
T218 29935-29999 Sentence denotes The schematic representation of the MEPVC is shown in Figure 3 .
T219 30000-30123 Sentence denotes CTB is nontoxic part of cholera toxin and is considered an accelerator in protective immunity and a break in auto-immunity.
T220 30124-30322 Sentence denotes It shows high affinity for monosialotetrahexosylganglioside displayed on variety of cell types, including gut epithelial cells, antigen-presenting cells (dendritic and macrophages) and B-cells [77].
T221 30323-30628 Sentence denotes CTB is a preferred choice as an adjuvant because of its ability of self-expression in variety of organisms and can be coupled to antigens through several approaches involving chemical manipulation and genetic fusion resulting in strong immunological responses against the antigens to which it is attached.
T222 30629-30821 Sentence denotes The vaccine construct was then used in a comparative 3D structure prediction to ensure confidentiality in selection of the most suitable model for the construct with minimum structural errors.
T223 30822-30876 Sentence denotes Fig. 3 Schematic representation of the designed MEPVC.
T224 30878-30923 Sentence denotes 3.5 Evaluation of Physicochemical Properties
T225 30924-31013 Sentence denotes Several different physicochemical properties of the MEPVC were deduced from its sequence.
T226 31014-31092 Sentence denotes The vaccine construct is 189 amino acids long with total number of 2984 atoms.
T227 31093-31238 Sentence denotes The molecular weight of the construct is ideal i.e. 21.36 kD as small size construct is easy to handle and purify during experimental evaluation.
T228 31239-31321 Sentence denotes The construct has instability index value of 35.43, signifying its high stability.
T229 31322-31411 Sentence denotes The aliphatic index computed for the construct is 79.68, reflecting high thermostability.
T230 31412-31530 Sentence denotes The estimated half-life in mammals, yeast, and Escherichia coli is 30 hours, > 20 hours, and > 10 hours, respectively.
T231 31531-31644 Sentence denotes The Grand average of hydropathicity (GRAVY) score is -0.315 which highlights hydrophilic nature of the construct.
T232 31645-31717 Sentence denotes The theoretical pI is 6.10 pointing to construct slightly acidic nature.
T233 31719-31762 Sentence denotes 3.6 MEPVC Secondary and Tertiary Structure
T234 31763-32029 Sentence denotes The secondary structure elements of the vaccine construct can be divided into the following order: alpha helix (56.08 %), 310 helix (0 %), Pi helix (0 %), beta bridge (0 %), extended strand (16.40 %), beta-turn (7.94 %), bend region (0 %), and random coil (19.58 %).
T235 32030-32235 Sentence denotes Compared to the I-tasser, phyre2, and Swiss-model, the 3Dpro predicted structure was determined as the most suitable structure based on the complete modeling of the given length of the amino acid sequence.
T236 32236-32347 Sentence denotes Loop modeling was done at Leu29-Gln37, Ser51-Gln70, Glu72-Gln77, Glu57-Ser76, Val103-Thr113, and Glu167-Asp186.
T237 32348-32546 Sentence denotes The model was refined to minimum RMSD of 1.734 Å and molprobity score of 1.134 that is quite low compared to the original structure score of 3.312, reflecting good quality of the modelled structure.
T238 32547-32674 Sentence denotes Similarly, the clash score in contrast to the original structure is 94.7 times lower demonstrating steric clash free structure.
T239 32675-32804 Sentence denotes The galaxy energy of the structure is very stable (-3784.31) and Ramachandran favored distribution increased from 93.6 to 95.7 %.
T240 32805-32869 Sentence denotes The top 10 refined models of the MEPVC are tabulated in Table 2.
T241 32870-32972 Sentence denotes The 3D models of the vaccine construct after loop modelling and refinement is presented in Figure 4.A.
T242 32973-33144 Sentence denotes The overall Z-score of the modelled structure is -4 and the score is within the range of same size proteins in the pdb illustrating good quality as depicted in Figure 4.B.
T243 33145-33424 Sentence denotes Refinement of the structure Ramachandran plot demonstrated the construct to contain 93.2 % of its residues in the most favored regions, while 5.7%, 0.0%, 1.1% residues are in additional allowed region, generously allowed region, and disallowed regions, respectively (Figure 4.C).
T244 33425-33479 Sentence denotes The overall average G-factor of the construct is 0.05.
T245 33480-33489 Sentence denotes Fig. 4 A.
T246 33490-33535 Sentence denotes The tertiary structure of the designed MEPVC.
T247 33536-33652 Sentence denotes The red, green, purple, and yellow colors represent AAY linkers, epitopes, adjuvant, and EAAK linkers, respectively.
T248 33653-33655 Sentence denotes B.
T249 33656-33722 Sentence denotes The z-score plot indicating the overall good quality of the MEPVC.
T250 33723-33852 Sentence denotes The z-score of the input MEPVC is shown by a black dot, validating the score within the range revealed for similar size proteins.
T251 33853-33855 Sentence denotes C.
T252 33856-34023 Sentence denotes Ramachandran plot for the MEPVC illustrating distribution of torsion angles (blue squares) comparative to the core (shown in red) and allowed (shown in brown) regions.
T253 34024-34146 Sentence denotes Residues in the generously allowed region are shown in dark yellow whereas disallowed regions are depicted in pale yellow.
T254 34148-34183 Sentence denotes 3.7 Disulfide Engineering of MEPVC
T255 34184-34344 Sentence denotes Enhancing protein stability is important in many biomedical applications and is an appealing approach to emulate nature stabilizing molecular interactions [78].
T256 34345-34519 Sentence denotes The covalent disulfide bonds provide substantial stability to target proteins and disulfide engineering had achieved considerable success in broad range of applications [33].
T257 34520-34606 Sentence denotes In total, 11 pairs of residues were selected for the purpose of disulfide engineering.
T258 34607-34775 Sentence denotes These include Met1-Ser81, Lys5-Ala59, Val12-Asp28, Ser16-Asp28, Thr40-Ser47, Val73-Gln77, Ala119-Ala133, Met122-Ala133, Ala126-Asp129, Leu156-Leu163, and Asn159-Asp162.
T259 34776-34899 Sentence denotes The average Chi3 and energy value for the pairs is 12.54 (max, 108.65 and min, -110.64) and 3.12 (max, 4.39 and min, 1.14).
T260 34900-34967 Sentence denotes The disulfide engineered MEPVC structure is presented in Figure 5 .
T261 34968-35010 Sentence denotes Fig. 5 Disulfide engineering of the MEPVC.
T262 35011-35057 Sentence denotes The yellow spheres represent mutated residues.
T263 35059-35104 Sentence denotes 3.8 Codon Optimization and In Silico Cloning
T264 35105-35201 Sentence denotes In the follow up experimental studies, the maximum expression of MEPVC is highly desirable [35].
T265 35202-35380 Sentence denotes One requirement for that is the codon usage of MEPVC that must be adapted according to the expression system, for instance, here we used E. coli K12 as a MEPVC expression system.
T266 35381-35573 Sentence denotes The codon adaptation index (CAI) and GC content revealed for the improved sequence are highly satisfactory with value of 0.96 and 48.85, respectively strongly indicating high MEPVC expression.
T267 35574-35741 Sentence denotes The MEPVC then enclosed on both sites by 6x histidine tag to ease its purification process and inserted at appropriate sites of pET28a(+) vector as shown in Figure 6 .
T268 35742-35814 Sentence denotes Fig. 6 In silico restriction cloning of the MEPVC into pET28a(+) vector.
T269 35815-35842 Sentence denotes The insert is shown in red.
T270 35844-35889 Sentence denotes 3.9 MEPVC Interactions with Immune Receptors
T271 35890-36058 Sentence denotes Molecular interactions and binding conformation of the designed MEPVC with TLR3 and TLR4 innate immune receptors were deciphered via a protein-peptide docking approach.
T272 36059-36319 Sentence denotes Both TLR3 and TLR4 belong to toll-like receptor family of pattern recognition receptor and function to activate intracellular signaling NF-κB pathway and production of inflammatory cytokines responsible for the development of effective innate immunity [79,80].
T273 36320-36477 Sentence denotes These receptors recognize viral associated molecular patterns and induce the production of interferon leading to activation of strong host defense responses.
T274 36478-36640 Sentence denotes Also, the specific adaptive immunity takes time to establish against antigens therefore it's important to evaluate MEPVC affinity for the innate immune receptors.
T275 36641-36793 Sentence denotes In case of MRPVC-TLR3 complex, the patch dock predicted 10 best solutions sorted based on the docking geometric shape complementarity score (S-Table 3).
T276 36794-36936 Sentence denotes A high score implies enhanced affinity of the interacting molecules and best docked conformations of the molecules with respect to each other.
T277 36937-37066 Sentence denotes Solution 3 was visualized for docked conformations and intermolecular forces responsible for such high affinity of the molecules.
T278 37067-37249 Sentence denotes The selection was based on the FireDock analysis (S-Table 4) which is an efficient package for refinement and reassigning procedure of docking scores to rigid body docking solutions.
T279 37250-37362 Sentence denotes The global binding energy of solution 3 is better i.e. -6.39 kJ/mol compared to the rest of predicted solutions.
T280 37363-37586 Sentence denotes The contribution to the total score form attractive van der Waals (VdW) energy is -12.12 kJ/mol, repulsive (VdW) energy (4.79 kJ/mol), hydrogen bond (HB) energy (-1.63 kJ/mol), and atomic contact energy (ACE) (5.95 kJ/mol).
T281 37587-38025 Sentence denotes The MEPVC, within 3 Å, was noticed to posed right in the center of the TLR3 receptor (Figure 7 ) interacting via hydrogen and hydrophobic bonds with His156, Asp180, Lys201, Glu203, Ser206, Phe227, Asp229, Asp230, Ser254, Ser256, Asp257, Ser282, Tyr283, Asp284, Asp285, Glu301, Tyr302, Phe304, Glu306, Tyr307, Arg325, Glu358, His359, Lys382, Tyr383, P408, His410, Iso411, Gly431, His432, Glu434, Pro408, Asp457, Phe459, Gln483, and Glu533.
T282 38026-38261 Sentence denotes Similarly, among 10 predicted MEPVC-TLR4 complexes (S-Table 5), solution 7 (S-Table 6) was affirmed as best with total global energy of -10.39 kJ/mol whereas the rest of complexes were noticed as highly unstable with score in positive.
T283 38262-38419 Sentence denotes The attractive VdW, repulsive VdW, HB and ACE contribution to the global energy is -35.75 kJ/mol, 22.04 kJ/mol, -5.51 kJ/mol, and 12.61 kJ/mol, respectively.
T284 38420-38528 Sentence denotes Visual analysis of the complex revealed binding of the MEPVC at the interface of chains B and D (Figure 8 ).
T285 38529-38573 Sentence denotes The MEPVC is surrounded by chain B residues:
T286 38574-38724 Sentence denotes Pro23, Glu24, Ser25, Asp44, Lys47, Asp50, Asp51, Arg67, Arg87, Glu89, Pro113, Gln115, Asp137, His159, Asp160, Ser184, and Lys186 and chain D residues:
T287 38725-38750 Sentence denotes Lys20, Phe64, and Asp114.
T288 38751-38832 Sentence denotes Fig. 7 Binding conformation of MEPVC with respect to TLR3 innate immune receptor.
T289 38833-38953 Sentence denotes The yellow labeled region pointing to the residues involved in both hydrophobic and hydrophilic interactions with MEPVC.
T290 38954-39035 Sentence denotes Fig. 8 Binding conformation of MEPVC with respect to TLR4 innate immune receptor.
T291 39036-39156 Sentence denotes The yellow labeled region pointing to the residues involved in both hydrophobic and hydrophilic interactions with MEPVC.
T292 39158-39195 Sentence denotes 3.10 Computational Immune Simulation
T293 39196-39338 Sentence denotes The dynamic simulations of the human immune system in response to the designed vaccine construct were deciphered through C-immsim server [40].
T294 39339-39434 Sentence denotes The vaccine construct upon administration revealed to generate robust primary immune responses.
T295 39435-39592 Sentence denotes As can be seen in Figure 9A that combine IgM and IgG antibodies has a titer scale close to 10,000/ml followed by IgM antibody (> 6000 antibody titer per ml).
T296 39593-39713 Sentence denotes The combined IgG1 and IgG2 and IgG1 were seen to generate high titer scale of around 6300/ml, 3100/ml, and respectively.
T297 39714-39806 Sentence denotes The IgG2 antibody response revealed to be low throughout post vaccine administration period.
T298 39807-39903 Sentence denotes The dimerized soluble cytokine IFN-g produced against the antigen is > 400000 ng/ml (Figure 9B).
T299 39904-39984 Sentence denotes Fig. 9 In silico simulation of the host immune system using MEPVS as an antigen.
T300 39985-39987 Sentence denotes A.
T301 39988-40071 Sentence denotes Antibodies titer (A) and cytokines and interleukins (B) in response to the antigen.
T302 40073-40108 Sentence denotes 3.11 Molecular Dynamics Simulation
T303 40109-40470 Sentence denotes The stability and dynamics of the designed vaccine construct ensemble docked to innate immune receptors were disclosed through 100-ns of MD production run and interpreted through the root mean square deviation (RMSD) [81], root mean square fluctuation (RMSF) 82, the radius of gyration (Rg) [83] and beta factor (β-factor) [84] assays as depicted in Figure 10 .
T304 40471-40600 Sentence denotes Fig. 10 MD trajectories based calculation of Cα RMSD (top left), RMSD (top right), Rg (bottom left), and β-factor (bottom right).
T305 40601-40711 Sentence denotes The average Cα atomic distance over 10,000 frames of TLR3-MEPVC and TLR4-MEPVC was decoded through RMSD assay.
T306 40712-40844 Sentence denotes An average RMSD of 3.44 Å (maximum, 6.30 Å) and 3.36 Å (maximum, 5.22 Å) were estimated for TLR3-MEPVC and TLR4-MEPVC, respectively.
T307 40845-41075 Sentence denotes The TLR3 and TLR4 receptors are observed more compact than the MEPVC and as a result, continuous movements of the vaccine construct through its length are noticed at the exposed regions though rooted stable at the docked position.
T308 41076-41163 Sentence denotes This seems to be responsible for bringing small structural deviation as probed by RMSD.
T309 41164-41321 Sentence denotes Visual inspection of the trajectories illustrated no major global and local secondary structure conformation changes in the receptor TLR3 and TLR4 structure.
T310 41322-41429 Sentence denotes The MEPVC movements with respect to the TLR3 are shown at different snapshots as illustrated in Figure 11 .
T311 41430-41592 Sentence denotes The MEPVC seems responsible for the deviations in the receptor TLR4 at positions Glu1-Ser79, Hie540-Asn614, Gln1144-Gln1209, Gln1347-Pro1371, and Lys1489-Lys1491.
T312 41593-41784 Sentence denotes Continuous flexibility of the loops of MEPVC exposed region is observed and is highly flexible responsible for the movements of the MEPVC at the docked site though rooted stably (Figure 12 ).
T313 41785-41862 Sentence denotes Fig. 11 Binding mode of MEPVC at different snapshots at the TLR3 docked side.
T314 41863-41940 Sentence denotes Fig. 12 Binding mode of MEPVC at different snapshots at the TLR4 docked side.
T315 41941-42134 Sentence denotes The second statistical parameter computed for both complexes was the root mean square fluctuations (RMSF) that demonstrate average dynamical residue fluctuations over a specific length of time.
T316 42135-42257 Sentence denotes The mean RMSF concluded for TLR3-MEPVC system is 2.1 Å whereas, an average RMSF of 2.03 Å for TLR4-MEPVC was demonstrated.
T317 42258-42371 Sentence denotes Majority of the receptors residues are showing less variability and are satisfactory stable with mean RMSF < 3 Å.
T318 42372-42504 Sentence denotes The residues range mentioned above were reported to have higher RMSF values and revealed fluctuating throughout the simulation time.
T319 42505-42596 Sentence denotes These fluctuations are in all likelihood as an outcome of the moving adjuvant of the MEPVC.
T320 42597-42709 Sentence denotes This is supported by the fact that the mean RMSF of the MEPVC is comparatively very high than that of receptors.
T321 42710-42816 Sentence denotes The RMSF of MEPVC in TLR3-MEPVC and TLR4-MEPVC is 1.86 Å (maximum, 10.16 Å) and 7.45 Ǻ (maximum, 13.04 Ǻ).
T322 42817-43027 Sentence denotes The receptors stability in both complexes is reaffirmed by radius of gyration (Rg) analysis that depicted stable plot with mean value of 33.97 Å (maximum, 35.62 Å) and 41.01 Ǻ (maximum, 41.65 Ǻ) for TLR4-MEPVC.
T323 43028-43151 Sentence denotes The Rg findings are coherent with that of RMSD in interpreting systems stable behavior and compact nature of the receptors.
T324 43152-43256 Sentence denotes Lastly, thermal beta factor (β-factor) indicated the same pattern of residues dynamics as shown by RMSF.
T325 43257-43357 Sentence denotes An average β-factor derived from TLR3-MEPVC and TLR4-MEPVC is 121.34 Ų and 123.47 Ų, respectively.
T326 43359-43387 Sentence denotes 3.12 Hydrogen bond analysis
T327 43388-43526 Sentence denotes Hydrogen bonding results when a hydrogen atom attached to a highly electronegative atom is attracted by another electronegative atom [85].
T328 43527-43670 Sentence denotes In a biological system, these hydrogen bonds are vital in determining specificity and directionality fundamental in molecular recognition [86].
T329 43671-43853 Sentence denotes The patterns of hydrogen bonds for both complexes were illustrated in each frame within 3 Å in order to probe the strength of intermolecular association across the simulation period.
T330 43854-43995 Sentence denotes The maximum number of hydrogen bonds of MEPVC with TLR3 and TLR4 are 11 and 12, respectively demonstrating the high strength of interactions.
T331 43996-44068 Sentence denotes The number of hydrogen bonds for both complexes are shown in Figure 13 .
T332 44069-44173 Sentence denotes Fig. 13 The number of hydrogen bonds formed during simulation between MEPVC and TLR3 and TLR4 receptors.
T333 44175-44205 Sentence denotes 3.13 Analysis of Salt bridges
T334 44206-44310 Sentence denotes In a protein molecule, salt bridges are formed between charged side chains of amino acids at neutral pH.
T335 44311-44492 Sentence denotes The residues mainly involved in these interactions include negative full electron charge glutamine and aspartate and opposite positive full electron charge arginine and lysine [87].
T336 44493-44611 Sentence denotes The presence of salt bridges between the interacting molecules is a clear sign of strengthening interaction stability.
T337 44612-44788 Sentence denotes For TLR3-MEPVC complex high numbers of salt bridges were estimated within 3.2 Å between receptor Glu8, Glu276, Arg306, Glu333 with MEPVC Lys3, Lys8, Glu83, Arg16, respectively.
T338 44789-44950 Sentence denotes In case of TLR4-MEPVC complex, receptor residues Arg646, Asp268, Arg1396 are involved in salt bridging with Asp146, Arg175 and Glu184 of the MEPVC, respectively.
T339 44952-44993 Sentence denotes 3.14 Estimation of Binding Free Energies
T340 44994-45140 Sentence denotes The binding free energies of both TLR3-MEPVC and TLR4-MEPVC complexes were computed using continuum solvation MMPBSA and its complementary MMGBSA.
T341 45141-45296 Sentence denotes The binding free energies of the vaccine construct for the receptors were estimated considering molecular mechanics energies as well as solvation energies.
T342 45297-45429 Sentence denotes The net binding free energy for both complexes revealed to be very high illustrating the high interacting affinity of the molecules.
T343 45430-45561 Sentence denotes For TLR3-MEPVC, the total free energy of binding is -41.4273 kcal/mol in MMGBSA while in MMPBSA it is -84.4908 kcal/mol (Table 3 ).
T344 45562-45686 Sentence denotes In case of TLR4-MEPVC, the net binding energy is -13.9690 kcal/mol and -21.2289 kcal/mol in MMGBSA and MMPBSA, respectively.
T345 45687-45811 Sentence denotes The gas phase energy in TLR3-MEPVC complex is highly dominating and contributes significantly to the overall binding energy.
T346 45812-45918 Sentence denotes The total gas phase energy of TLR3-MEPVC is -530.5792 kcal/mol in MMGBSA and -530.5792 kcal/mol in MMPBSA.
T347 45919-46090 Sentence denotes The electrostatic contribution to the net gas phase energy is high i.e. -393.2724 kcal/mol in both MMGBSA and MMPBSA compared to van der Waals energy (-137.3068 kcal/mol).
T348 46091-46272 Sentence denotes The electrostatic energy contribution to the solvation energy is 507.5596 kcal/mol in MMGBSA and 462.9381 kcal/mol in MMPBSA and is highly non-favorable to the net solvation energy.
T349 46273-46472 Sentence denotes For TLR4-MEPVC, the net MMPBSA is the comparatively high (-21.2289 kcal/mol) than the MMGBSA (-13.9690 kcal/mol) with solvation energy noticed to dominate the overall interaction energies (Table 4 ).
T350 46473-46658 Sentence denotes The solvation energy in MMGBSA and MMPBSA is -245.2265 kcal/mol (electrostatic contribution, -240.2983 kcal/mol) and -252.4865 kcal/mol (electrostatic contribution, -248.2779 kcal/mol).
T351 46659-46872 Sentence denotes The net gas phase energy is 231.2576 kcal/ mol in both MMGBSA and MMPBSA and major favorable contribution is from van der Waals is -35.8526 kcal/mol opposed to the non-favorable contributions is 267.1101 kcal/mol.
T352 46873-47128 Sentence denotes Residue wise, most of the interacting residues of TLR3 reported in docking assay have very low binding energy reflecting the highly stable nature of these residues in interaction and the key role they are playing in holding the MEPVC at the docked region.
T353 47129-47186 Sentence denotes The binding energy of the hotspot residues are as follow:
T354 47187-47990 Sentence denotes His156 (-2.14 kcal/mol), Asp180 (-6.21 kcal/mol), Lys201 (-1.23 kcal/mol), Glu20 (-2.13 kcal/mol), Ser206 (-0.43 kcal/mol), Phe227 (-3.45 kcal/mol), Asp229 (-1.51 kcal/mol), Asp230 (-1.88 kcal/mol), Ser254 (-2.98 kcal/mol), Ser256 (-1.52 kcal/mol), Ser282 (-1.21 kcal/mol), Asp284 (-1.99 kcal/mol), Asp285 (-0.23 kcal/mol), Glu301 (-3.13 kcal/mol), Tyr302 (-1.48 kcal/mol), Phe304 (-3.52 kcal/mol), Glu306 (-3.43 kcal/mol), Tyr307 (-2.89 kcal/mol), Arg325 (-8.12 kcal/mol), His359 (-0.17 kcal/mol), Lys382 (-0.43 kcal/mol), Tyr383 (-3.27 kcal/mol), Pro408 (-2.22 kcal/mol), His410 (-1.16 kcal/mol), Iso411 (-1.81 kcal/mol), His432 (-1.76 kcal/mol), Glu434 (-2.77 kcal/mol), Pro408 (-3.11 kcal/mol), Asp457 (-1.15 kcal/mol), Phe459 (-.5.12 kcal/mol), Gln483 (-4.11 kcal/mol), and Glu533 (-1.23 kcal/mol).
T355 47991-48525 Sentence denotes In case of TLR4-MEPVC, docking residues Pro23 (-1.54 kcal/mol), Glu24 (-2.31 kcal/mol), Ser25 (-3.33 kcal/mol), Asp44 (-4.43 kcal/mol), Lys47 (-5.23 kcal/mol), Asp50 (-2.21 kcal/mol), Asp51 (-1.99 kcal/mol), Arg67 (-5.65 kcal/mol), Arg87 (-1.21 kcal/mol), Glu89 (-2.11 kcal/mol), Pro113 (-0.12 kcal/mol), Gln115 (-1.21 kcal/mol), Asp137 (-0.23 kcal/mol), His159 (-3.22 kcal/mol), and Asp160 (-2.43 kcal/mol) from chain B and Lys20 (-2,89 kcal/mol), Phe64 (3.21 kcal/mol), and Asp114 (-2.11 kcal/mol) from chain D are hotspot residues.
T356 48526-48639 Sentence denotes Table 3 Differences of binding free energy (Complex - Receptor - Ligand) in MMGB/PBSA for the TLR3-MEPVC complex.
T357 48640-48680 Sentence denotes Method Net Energy Component Average Std.
T358 48681-48685 Sentence denotes Dev.
T359 48686-48690 Sentence denotes Std.
T360 48691-48703 Sentence denotes Err. of Mean
T361 48704-48741 Sentence denotes MMGBSA DWAALS -137.3068 7.0875 0.7088
T362 48742-48770 Sentence denotes EEL -393.2724 43.8913 4.3891
T363 48771-48798 Sentence denotes EGB 507.5596 41.1568 4.1157
T364 48799-48827 Sentence denotes ESURF -18.4077 0.8700 0.0870
T365 48828-48864 Sentence denotes DELTA G gas -530.5792 41.8517 4.1852
T366 48865-48901 Sentence denotes DELTA G solv 489.1519 41.4134 4.1413
T367 48902-48936 Sentence denotes DELTA TOTAL -41.4273 7.7453 0.7745
T368 48937-48975 Sentence denotes MMPBSA VDWAALS -137.3068 7.0875 0.7088
T369 48976-49004 Sentence denotes EEL -393.2724 43.8913 4.3891
T370 49005-49032 Sentence denotes EPB 462.9381 39.2924 3.9292
T371 49033-49063 Sentence denotes ENPOLAR -16.8497 0.6609 0.0661
T372 49064-49092 Sentence denotes EDISPER 0.0000 0.0000 0.0000
T373 49093-49129 Sentence denotes DELTA G gas -530.5792 41.8517 4.1852
T374 49130-49166 Sentence denotes DELTA G solv 446.0884 39.5288 3.9529
T375 49167-49202 Sentence denotes DELTA TOTAL -84.4908 10.3941 1.0394
T376 49203-49316 Sentence denotes Table 4 Differences of binding free energy (Complex - Receptor - Ligand) in MMGB/PBSA for the TLR4-MEPVC complex.
T377 49317-49357 Sentence denotes Method Net Energy Component Average Std.
T378 49358-49362 Sentence denotes Dev.
T379 49363-49367 Sentence denotes Std.
T380 49368-49380 Sentence denotes Err. of Mean
T381 49381-49417 Sentence denotes MMGBSA DWAALS -35.8526 3.0453 0.3045
T382 49418-49445 Sentence denotes EEL 267.1101 29.5270 2.9527
T383 49446-49474 Sentence denotes EGB -240.2983 27.5172 2.7517
T384 49475-49502 Sentence denotes ESURF -4.9282 0.3849 0.0385
T385 49503-49538 Sentence denotes DELTA G gas 231.2576 29.5487 2.9549
T386 49539-49576 Sentence denotes DELTA G solv -245.2265 27.4463 2.7446
T387 49577-49611 Sentence denotes DELTA TOTAL -13.9690 4.2201 0.4220
T388 49612-49649 Sentence denotes MMPBSA VDWAALS -35.8526 3.0453 0.3045
T389 49650-49677 Sentence denotes EEL 267.1101 29.5270 2.9527
T390 49678-49706 Sentence denotes EPB -248.2779 27.2761 2.7276
T391 49707-49736 Sentence denotes ENPOLAR -4.2085 0.2122 0.0212
T392 49737-49765 Sentence denotes EDISPER 0.0000 0.0000 0.0000
T393 49766-49801 Sentence denotes DELTA G gas 231.2576 29.5487 2.9549
T394 49802-49839 Sentence denotes DELTA G solv -252.4865 27.2706 2.7271
T395 49840-49874 Sentence denotes DELTA TOTAL -21.2289 5.3805 0.5380
T396 49876-49910 Sentence denotes 3.15 Probable Prevention Strategy
T397 49911-50107 Sentence denotes After performing the immune system simulation to MEPVC and a thorough peptide dynamics analysis, a novel MEPVC is proposed as a probable solution to the widely spread viral coronaviruses outbreak.
T398 50108-50272 Sentence denotes Meanwhile, this seems necessary to have a deep down lesson as COVID-19 viral outbreak is propagating to the human species on this part of the universe called Earth.
T399 50273-50498 Sentence denotes As we are already living under a serious threat of antibiotic and antimicrobial resistance [88] which if ignored can cause havoc and the current spread of COVID-19 is a clear example of even a viral resistance coming in line.
T400 50499-50778 Sentence denotes Referring to the introduction section where the probable cause of this viral attack is discussed, this is mandatory to mention that there is retaliation from animals and animal-associated viruses or bacteria observed against Homo sapiens quite frequently in the recent past [89].
T401 50779-50951 Sentence denotes This not only alarms the way of consuming animals in our food in the form of livestock but at the same time explains the advancing defense system of various species around.
T402 50952-51140 Sentence denotes Either it is horizontal gene transfer among bacteria or transient nature of viral transmission throughout the world as one way or the other this is a form of advanced defense of organisms.
T403 51141-51268 Sentence denotes It is meant to state that even before and after the Cognitive Revolution, Homo sapiens cannot be exempted from biological laws.
T404 51269-51442 Sentence denotes While considering under the realm of these biological laws this is much expected from all other species to have the right of keeping and exercising a defense mechanism [90].
T405 51443-51642 Sentence denotes Instead of spending on wars among humans there is a dire need to be equipped for all wars to come against human species under the disguise of either environmental hazards or antimicrobial resistance.
T406 51643-51696 Sentence denotes Even viruses are finding new ways of infecting hosts.
T407 51697-51799 Sentence denotes Under this perspective the role of avian has been observed as much dominating in the recent past [91].
T408 51800-52004 Sentence denotes After having insights from comparative advancing mechanism we mention here and thereafter the preliminary existence of a “Theory of Retaliation” on the basis of currently available facts and observations.
T409 52005-52068 Sentence denotes This theory of retaliation will play its role in coming future.
T410 52069-52181 Sentence denotes The continuous attacks in the form of outbreaks by them have raised many challenges and threats to human beings.
T411 52182-52380 Sentence denotes A recent mechanism study by Bazel et al reported H5N1 influenza viruses is posing threat to human and animal health and is currently unclear what restricts these interspecies jumps on the host side.
T412 52381-52554 Sentence denotes It is further signified that PB1-F2 (a short viral peptide) assists H5N1 bird influenza viruses to overcome a human restriction factor of the viral polymerase complex HAX-1.
T413 52555-52666 Sentence denotes It is also evidenced that a functional PB1-F2 aids in direct transmission of viruses from birds to humans [92].
T414 52667-52823 Sentence denotes Additionally, there is already a mechanism existing for the antimicrobial defense of avian eggs which illustrates their efficacy in defense mechanisms [93].
T415 52824-52985 Sentence denotes Furthermore, discovery of avian antimicrobial peptides, classified as B-defensins, present in chicken and turkey found active against bacteria, fungi, and yeast.
T416 52986-53156 Sentence denotes This is another example of advance mechanism showed by avian and the possibility of a common ancestral gene between avian and other mammalian peptides seems obvious [94].
T417 53157-53346 Sentence denotes WHO alarmed quite often that influenza viruses with a vast silent reservoir in aquatic birds are impossible to eradicate while avian influenza is proved to be a threat to human health [95].
T418 53347-53539 Sentence denotes Even having the phylogenetic identity between SARS-CoV-2 and SARS-CoV, some clinical characteristics differentiate SARS-CoV-2 from SARS-CoV, MERS-CoV, and seasonal influenza infections [2,96].
T419 53540-53641 Sentence denotes This leads to the fact that viruses are attacking humans with different clinical features every time.
T420 53642-53781 Sentence denotes The complex relationships between the human and animal species never faced a halt in evolving giving rise to numerous infectious pathogens.
T421 53782-54090 Sentence denotes Whatsoever is the case, the dramatic impact of infectious diseases affecting the modern human population worldwide is evident and unexpected rise of coronavirus infections raised to 100000 while writing this research and getting beyond the normal control (https://www.nature.com/articles/d41586-020-00154-w).
T422 54091-54202 Sentence denotes After all we belong to the kingdom Animalia with even ten on ten embarrassing similarities to chimpanzees [97].
T423 54203-54415 Sentence denotes Probable prevention in this context is to somehow avoid the excruciating utilization and consumption of other mammals as edibles from Homo sapiens and stop becoming a reason for the extinction of certain species.
T424 54416-54599 Sentence denotes Avenging from these species from time to time by utilizing the microbes associated with them against human has become obvious and vaccine design and discovery is of utmost importance.
T425 54600-54849 Sentence denotes This is crucial to strategize a preventive control not only for symptomatic relief but in general taking steps to prevent hunting and strategy required to maintain a balanced ecosystem where specifically avian will not dwell under threat by sapiens.
T426 54850-54998 Sentence denotes The advent of various new mechanisms of viral survival has remained sapiens perplexed and a broader strategy is required to circumvent this problem.
T427 55000-55014 Sentence denotes 4 Conclusions
T428 55015-55214 Sentence denotes In this study, we used available immunoinformatics approaches for the purpose to prioritize potential vaccine candidates against COVID-19 considering their ease of use in experimental investigations.
T429 55215-55403 Sentence denotes Bearing in mind, the wide immunological applications of peptide vaccines only highly antigenic, virulent, conserved and non-allergic epitopes targeted by both B and T-cells were disclosed.
T430 55404-55557 Sentence denotes A multi-epitope peptide was constructed and an appropriate adjuvant was added to allow suitable delivery and efficient immune processing of the epitopes.
T431 55558-55771 Sentence denotes These promising computational findings might deliver preliminary epitopes set for a vaccine against the COVID-19 notwithstanding the experimental testing in appropriate animal models to unravel real effectiveness.
T432 55772-56065 Sentence denotes Meanwhile, probable prevention discussed in this study for Homo sapiens is to avoid becoming a reason for the extinction of various species either by hunting and/or over utilizing other mammals as this may be a reason for resistance both from microbes and other animal species of this kingdom.
T433 56066-56204 Sentence denotes There must be strategic studies keeping in view the advancements in defense mechanism of avian and avian related microbes avenging humans.
T434 56205-56405 Sentence denotes Preventive use of animals or avian in human diet and avoiding hunting can be preventive options for self-defense in this connection and/or maintenance of a balanced ecosystem should be reinvestigated.
T435 56407-56430 Sentence denotes 5 Disclosure Statement
T436 56431-56483 Sentence denotes No conflict of interest was reported by the authors.
T437 56485-56508 Sentence denotes Credit Author Statement
T438 56509-56522 Sentence denotes Sajjad Ahmad:
T439 56523-56621 Sentence denotes Conceptualization, Methodology, Writing- Original Draft Preparation, Visualization, Investigation.
T440 56622-56634 Sentence denotes Afifa Navid:
T441 56635-56707 Sentence denotes Data Curation, Writing- Original Draft Preparation, Figures Preparation.
T442 56708-56720 Sentence denotes Rabia Farid:
T443 56721-56793 Sentence denotes Data Curation, Figures Preparation, Writing- Original Draft Preparation.
T444 56794-56807 Sentence denotes Ghulam Abbas:
T445 56808-56835 Sentence denotes Methodology, Data Curation.
T446 56836-56849 Sentence denotes Faisal Ahmad:
T447 56850-56883 Sentence denotes Methodology, Figures Preparation.
T448 56884-56896 Sentence denotes Naila Zaman:
T449 56897-56928 Sentence denotes Writing- Reviewing and Editing.
T450 56929-56946 Sentence denotes Nousheen Parvaiz:
T451 56947-56955 Sentence denotes Writing.
T452 56956-56975 Sentence denotes Syed Sikander Azam:
T453 56976-57115 Sentence denotes Supervision, Conceptualization, Methodology, Softwares, Resources, Funding Acquisition, Writing- Reviewing and Editing, Project Management.
T454 57117-57150 Sentence denotes Appendix Supplementary materials
T455 57152-57166 Sentence denotes Acknowledgment
T456 57167-57278 Sentence denotes Authors are highly grateful to the Pakistan-United States Science and Technology Cooperation Program (Grant No.
T457 57279-57330 Sentence denotes Pak-US/2017/360) for granting financial assistance.
T458 57331-57454 Sentence denotes Supplementary material associated with this article can be found, in the online version, at doi:10.1016/j.ejps.2020.105387.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 2407-2416 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 5310-5315 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T3 5317-5326 Phenotype denotes dry cough http://purl.obolibrary.org/obo/HP_0031246
T4 5328-5347 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T5 5352-5359 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T6 5361-5372 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T7 5377-5387 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T8 30109-30122 Phenotype denotes auto-immunity http://purl.obolibrary.org/obo/HP_0002960

2_test

Id Subject Object Predicate Lexical cue
32454128-31953166-29238294 3275-3276 31953166 denotes 4
32454128-31953166-29238295 5277-5278 31953166 denotes 4
32454128-27899561-29238296 6167-6168 27899561 denotes 9
32454128-23382822-29238297 6728-6730 23382822 denotes 10
32454128-30797936-29238298 6944-6946 30797936 denotes 11
32454128-11590105-29238299 7043-7045 11590105 denotes 13
32454128-15374866-29238300 7175-7177 15374866 denotes 14
32454128-10341176-29238301 7289-7291 10341176 denotes 15
32454128-30797936-29238302 7636-7638 30797936 denotes 11
32454128-16635264-29238303 7809-7811 16635264 denotes 17
32454128-28472356-29238304 7815-7817 28472356 denotes 18
32454128-12824380-29238305 8298-8300 12824380 denotes 19
32454128-18226234-29238306 8468-8470 18226234 denotes 21
32454128-28890542-29238307 9019-9021 28890542 denotes 24
32454128-26344743-29238308 9176-9178 26344743 denotes 25
32454128-28411163-29238309 9277-9279 28411163 denotes 26
32454128-28835708-29238310 9449-9451 28835708 denotes 27
32454128-15980571-29238311 9564-9566 15980571 denotes 28
32454128-18215316-29238312 9579-9581 18215316 denotes 29
32454128-29788355-29238313 9601-9603 29788355 denotes 30
32454128-16169926-29238314 9665-9667 16169926 denotes 31
32454128-23737448-29238315 9701-9703 23737448 denotes 32
32454128-3282505-29238316 9807-9809 3282505 denotes 33
32454128-21567958-29238317 10067-10069 21567958 denotes 35
32454128-15980527-29238318 10157-10159 15980527 denotes 36
32454128-29348555-29238319 10336-10338 29348555 denotes 37
32454128-30867498-29238320 10339-10341 30867498 denotes 38
32454128-28835708-29238321 10479-10481 28835708 denotes 27
32454128-20419125-29238322 11923-11925 20419125 denotes 41
32454128-15980490-29238323 12771-12773 15980490 denotes 42
32454128-25540183-29238324 13060-13062 25540183 denotes 44
32454128-8744570-29238325 13169-13171 8744570 denotes 46
32454128-8744570-29238326 15765-15767 8744570 denotes 46
32454128-25818402-29238327 19650-19652 25818402 denotes 20
32454128-24336184-29238328 20486-20488 24336184 denotes 61
32454128-22039154-29238329 21976-21978 22039154 denotes 62
32454128-26855426-29238330 22650-22652 26855426 denotes 66
32454128-30871454-29238331 25007-25009 30871454 denotes 69
32454128-24051159-29238332 25219-25221 24051159 denotes 70
32454128-12209139-29238333 26501-26503 12209139 denotes 72
32454128-14511229-29238334 27243-27245 14511229 denotes 74
32454128-25720354-29238335 27312-27314 25720354 denotes 75
32454128-28890542-29238336 29648-29650 28890542 denotes 24
32454128-26350596-29238337 29930-29932 26350596 denotes 76
32454128-25802972-29238338 30318-30320 25802972 denotes 77
32454128-24291258-29238339 34340-34342 24291258 denotes 78
32454128-3282505-29238340 34515-34517 3282505 denotes 33
32454128-21567958-29238341 35197-35199 21567958 denotes 35
32454128-25071777-29238342 36312-36314 25071777 denotes 79
32454128-27162029-29238343 36315-36317 27162029 denotes 80
32454128-20197040-29238344 40368-40370 20197040 denotes 82
32454128-31018129-29238345 44488-44490 31018129 denotes 87
32454128-21845185-29238346 51438-51440 21845185 denotes 90
32454128-15241422-29238347 51795-51797 15241422 denotes 91
32454128-15381059-29238348 53152-53154 15381059 denotes 94
32454128-17428885-29238349 53342-53344 17428885 denotes 95
32454128-27669147-29238350 54198-54200 27669147 denotes 97

MyTest

Id Subject Object Predicate Lexical cue
32454128-31953166-29238294 3275-3276 31953166 denotes 4
32454128-31953166-29238295 5277-5278 31953166 denotes 4
32454128-27899561-29238296 6167-6168 27899561 denotes 9
32454128-23382822-29238297 6728-6730 23382822 denotes 10
32454128-30797936-29238298 6944-6946 30797936 denotes 11
32454128-11590105-29238299 7043-7045 11590105 denotes 13
32454128-15374866-29238300 7175-7177 15374866 denotes 14
32454128-10341176-29238301 7289-7291 10341176 denotes 15
32454128-30797936-29238302 7636-7638 30797936 denotes 11
32454128-16635264-29238303 7809-7811 16635264 denotes 17
32454128-28472356-29238304 7815-7817 28472356 denotes 18
32454128-12824380-29238305 8298-8300 12824380 denotes 19
32454128-18226234-29238306 8468-8470 18226234 denotes 21
32454128-28890542-29238307 9019-9021 28890542 denotes 24
32454128-26344743-29238308 9176-9178 26344743 denotes 25
32454128-28411163-29238309 9277-9279 28411163 denotes 26
32454128-28835708-29238310 9449-9451 28835708 denotes 27
32454128-15980571-29238311 9564-9566 15980571 denotes 28
32454128-18215316-29238312 9579-9581 18215316 denotes 29
32454128-29788355-29238313 9601-9603 29788355 denotes 30
32454128-16169926-29238314 9665-9667 16169926 denotes 31
32454128-23737448-29238315 9701-9703 23737448 denotes 32
32454128-3282505-29238316 9807-9809 3282505 denotes 33
32454128-21567958-29238317 10067-10069 21567958 denotes 35
32454128-15980527-29238318 10157-10159 15980527 denotes 36
32454128-29348555-29238319 10336-10338 29348555 denotes 37
32454128-30867498-29238320 10339-10341 30867498 denotes 38
32454128-28835708-29238321 10479-10481 28835708 denotes 27
32454128-20419125-29238322 11923-11925 20419125 denotes 41
32454128-15980490-29238323 12771-12773 15980490 denotes 42
32454128-25540183-29238324 13060-13062 25540183 denotes 44
32454128-8744570-29238325 13169-13171 8744570 denotes 46
32454128-8744570-29238326 15765-15767 8744570 denotes 46
32454128-25818402-29238327 19650-19652 25818402 denotes 20
32454128-24336184-29238328 20486-20488 24336184 denotes 61
32454128-22039154-29238329 21976-21978 22039154 denotes 62
32454128-26855426-29238330 22650-22652 26855426 denotes 66
32454128-30871454-29238331 25007-25009 30871454 denotes 69
32454128-24051159-29238332 25219-25221 24051159 denotes 70
32454128-12209139-29238333 26501-26503 12209139 denotes 72
32454128-14511229-29238334 27243-27245 14511229 denotes 74
32454128-25720354-29238335 27312-27314 25720354 denotes 75
32454128-28890542-29238336 29648-29650 28890542 denotes 24
32454128-26350596-29238337 29930-29932 26350596 denotes 76
32454128-25802972-29238338 30318-30320 25802972 denotes 77
32454128-24291258-29238339 34340-34342 24291258 denotes 78
32454128-3282505-29238340 34515-34517 3282505 denotes 33
32454128-21567958-29238341 35197-35199 21567958 denotes 35
32454128-25071777-29238342 36312-36314 25071777 denotes 79
32454128-27162029-29238343 36315-36317 27162029 denotes 80
32454128-20197040-29238344 40368-40370 20197040 denotes 82
32454128-31018129-29238345 44488-44490 31018129 denotes 87
32454128-21845185-29238346 51438-51440 21845185 denotes 90
32454128-15241422-29238347 51795-51797 15241422 denotes 91
32454128-15381059-29238348 53152-53154 15381059 denotes 94
32454128-17428885-29238349 53342-53344 17428885 denotes 95
32454128-27669147-29238350 54198-54200 27669147 denotes 97