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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1 23-38 GO:0050817 denotes anticoagulation
T2 42-50 SP_7 denotes COVID-19
T3 102-113 NCBITaxon:11118 denotes Coronavirus
T4 131-139 SP_7 denotes COVID-19
T5 167-177 GO:0007596 denotes thrombotic
T6 208-223 GO:0050817 denotes anticoagulation
T7 278-293 GO:0050817 denotes Anticoagulation
T8 362-374 UBERON:0000970 denotes intracranial
T9 480-488 SP_7 denotes COVID-19
T10 534-549 GO:0050817 denotes anticoagulation
T11 626-634 SP_7 denotes COVID-19
T12 980-988 SP_7 denotes COVID-19
T13 1460-1475 GO:0050817 denotes anticoagulation
T14 1581-1596 GO:0050817 denotes Anticoagulation
T15 1640-1648 SP_7 denotes COVID-19
T16 1797-1808 NCBITaxon:11118 denotes Coronavirus
T17 1826-1834 SP_7 denotes COVID-19
T18 1866-1876 GO:0007596 denotes thrombotic
T19 1892-1900 SP_7 denotes COVID-19
T20 1966-1972 UBERON:0001638 denotes venous
T21 1973-1988 GO:0007596 denotes thromboembolism
T22 2036-2044 SP_7 denotes COVID-19
T23 2068-2079 GO:0050817 denotes coagulation
T24 2283-2298 GO:0050817 denotes anticoagulation
T25 2412-2427 GO:0050817 denotes anticoagulation
T26 2441-2450 UBERON:0002048 denotes pulmonary
T27 2494-2509 GO:0050817 denotes anticoagulation
T28 2565-2577 UBERON:0000970 denotes intracranial
T29 2636-2640 UBERON:0000165 denotes oral
T30 2641-2656 GO:0050817 denotes anticoagulation
T31 2891-2899 SP_7 denotes COVID-19
T32 2940-2948 SP_7 denotes COVID-19
T33 2976-2986 GO:0007596 denotes thrombosis
T34 3110-3118 SP_7 denotes COVID-19
T35 3172-3180 SP_7 denotes COVID-19
T36 3257-3265 SP_7 denotes COVID-19
T37 3318-3333 GO:0050817 denotes anticoagulation
T38 3472-3480 SP_7 denotes COVID-19
T39 3490-3495 UBERON:0007023 denotes adult
T40 4115-4120 UBERON:0000955 denotes brain
T41 4249-4257 SP_7 denotes COVID-19
T42 4553-4563 UBERON:0000074 denotes glomerular
T43 4624-4629 UBERON:0002113 denotes renal
T44 4661-4667 UBERON:0001638 denotes venous
T45 4668-4683 GO:0007596 denotes thromboembolism
T46 4717-4732 GO:0050817 denotes anticoagulation
T47 4782-4789 CHEBI:24505;CHEBI:24505 denotes heparin
T48 4807-4817 CHEBI:57472;CHEBI:57472 denotes argatroban
T49 5716-5724 UBERON:0001851 denotes cortical
T50 5802-5813 UBERON:0008987 denotes parenchymal
T53 6014-6022 SP_7 denotes COVID-19
T54 6720-6736 GO:0007596 denotes thrombocytopenic
T55 6742-6750 CL:0000233 denotes platelet
T65 6953-6965 UBERON:0000970 denotes intracranial
T77 7407-7419 GO:0050817 denotes  Congestive
T79 7841-7859 GO:0050817 denotes age Identification
T80 8047-8095 GO:0050817 denotes Encephalopathy 17 (51.5) 1 (20) 16 (57.1)  Focal
T81 8221-8242 UBERON:0010210 denotes Seizure like symptoms
T82 8656-8676 CHEBI:27641;CHEBI:27641 denotes prior to ICH, median
T83 8717-8751 CHEBI:31401;CHEBI:31401 denotes 2338 (1209–3030) Peak INR prior to
T84 8817-8841 CHEBI:27641;CHEBI:27641 denotes PTT prior to ICH, median
T85 9312-9327 GO:0050817 denotes anticoagulation
T86 9636-9651 GO:0050817 denotes anticoagulation
T87 9972-9987 GO:0050817 denotes anticoagulation
T88 10193-10205 UBERON:0000970 denotes intracranial
T89 11244-11259 GO:0050817 denotes anticoagulation
T90 11311-11326 GO:0050817 denotes anticoagulation
T91 11387-11402 GO:0050817 denotes anticoagulation
T92 11454-11469 GO:0050817 denotes anticoagulation
T93 11634-11642 UBERON:0010210 denotes thrombus
T94 11693-11708 GO:0050817 denotes anticoagulation
T95 11785-11792 CHEBI:24505;CHEBI:24505 denotes heparin
T96 12077-12084 CHEBI:24505;CHEBI:24505 denotes heparin
T97 12160-12170 GO:0042571 denotes antibodies
T98 12252-12267 GO:0050817 denotes anticoagulation
T99 12395-12406 UBERON:0008987 denotes parenchymal
T100 12670-12675 UBERON:0000955 denotes brain
T101 12762-12777 GO:0050817 denotes anticoagulation
T102 12830-12838 UBERON:0010210 denotes thrombus
T103 13325-13331 UBERON:0001851 denotes cortex
T104 13802-13817 GO:0050817 denotes anticoagulation
T105 13822-13830 SP_7 denotes COVID-19
T106 13957-13972 GO:0050817 denotes anticoagulation
T107 14019-14034 GO:0050817 denotes anticoagulation
T108 14165-14173 SP_7 denotes COVID-19
T109 14268-14283 GO:0050817 denotes anticoagulation
T110 14346-14361 GO:0050817 denotes anticoagulation
T111 14437-14452 GO:0050817 denotes anticoagulation
T112 14465-14473 SP_7 denotes COVID-19
T113 14832-14843 UBERON:0008987 denotes parenchymal
T114 15096-15111 GO:0050817 denotes anticoagulation
T115 15138-15148 GO:0007596 denotes thrombosis
T116 15194-15209 GO:0050817 denotes anticoagulation
T117 15265-15280 GO:0050817 denotes anticoagulation
T118 15325-15333 SP_7 denotes COVID-19
T119 15500-15515 GO:0050817 denotes anticoagulation
T120 15530-15538 SP_7 denotes COVID-19
T121 15591-15595 UBERON:0000033 denotes head
T122 15632-15647 GO:0050817 denotes anticoagulation
T123 15709-15721 UBERON:0001016 denotes neurological
T124 15904-15912 UBERON:0001851 denotes cortical
T125 16180-16188 SP_7 denotes COVID-19
T126 16566-16578 UBERON:0001016 denotes neurological
T127 16813-16821 SP_7 denotes COVID-19
T128 16839-16854 GO:0050817 denotes anticoagulation
T129 17018-17026 SP_7 denotes COVID-19
T130 17174-17189 GO:0050817 denotes anticoagulation
T131 17220-17228 SP_7 denotes COVID-19
T132 17302-17317 GO:0050817 denotes anticoagulation
T133 17322-17330 SP_7 denotes COVID-19
T67787 23-38 GO:0050817 denotes anticoagulation
T49280 42-50 SP_7 denotes COVID-19
T33732 102-113 NCBITaxon:11118 denotes Coronavirus
T70228 131-139 SP_7 denotes COVID-19
T83116 167-177 GO:0007596 denotes thrombotic
T11188 208-223 GO:0050817 denotes anticoagulation
T69400 278-293 GO:0050817 denotes Anticoagulation
T89853 362-374 UBERON:0000970 denotes intracranial
T17467 480-488 SP_7 denotes COVID-19
T69069 534-549 GO:0050817 denotes anticoagulation
T29420 626-634 SP_7 denotes COVID-19
T21455 980-988 SP_7 denotes COVID-19
T95287 1460-1475 GO:0050817 denotes anticoagulation
T6967 1581-1596 GO:0050817 denotes Anticoagulation
T8520 1640-1648 SP_7 denotes COVID-19
T73598 1797-1808 NCBITaxon:11118 denotes Coronavirus
T16957 1826-1834 SP_7 denotes COVID-19
T5584 1866-1876 GO:0007596 denotes thrombotic
T52328 1892-1900 SP_7 denotes COVID-19
T93778 1966-1972 UBERON:0001638 denotes venous
T46471 1973-1988 GO:0007596 denotes thromboembolism
T68763 2036-2044 SP_7 denotes COVID-19
T50994 2068-2079 GO:0050817 denotes coagulation
T68819 2283-2298 GO:0050817 denotes anticoagulation
T75390 2412-2427 GO:0050817 denotes anticoagulation
T70584 2441-2450 UBERON:0002048 denotes pulmonary
T55400 2494-2509 GO:0050817 denotes anticoagulation
T53351 2565-2577 UBERON:0000970 denotes intracranial
T63405 2636-2640 UBERON:0000165 denotes oral
T17341 2641-2656 GO:0050817 denotes anticoagulation
T81721 2891-2899 SP_7 denotes COVID-19
T29148 2940-2948 SP_7 denotes COVID-19
T59823 2976-2986 GO:0007596 denotes thrombosis
T26383 3110-3118 SP_7 denotes COVID-19
T84765 3172-3180 SP_7 denotes COVID-19
T63735 3257-3265 SP_7 denotes COVID-19
T94338 3318-3333 GO:0050817 denotes anticoagulation
T33588 3472-3480 SP_7 denotes COVID-19
T75181 3490-3495 UBERON:0007023 denotes adult
T11378 4115-4120 UBERON:0000955 denotes brain
T52216 4249-4257 SP_7 denotes COVID-19
T11336 4553-4563 UBERON:0000074 denotes glomerular
T12896 4624-4629 UBERON:0002113 denotes renal
T54987 4661-4667 UBERON:0001638 denotes venous
T42606 4668-4683 GO:0007596 denotes thromboembolism
T54361 4717-4732 GO:0050817 denotes anticoagulation
T80370 4782-4789 CHEBI:24505;CHEBI:24505 denotes heparin
T64123 4807-4817 CHEBI:57472;CHEBI:57472 denotes argatroban
T78498 5716-5724 UBERON:0001851 denotes cortical
T26933 5802-5813 UBERON:0008987 denotes parenchymal
T52 14832-14843 UBERON:0008987 denotes parenchymal
T68023 17302-17317 GO:0050817 denotes anticoagulation
T78495 17322-17330 SP_7 denotes COVID-19
T81663 15500-15515 GO:0050817 denotes anticoagulation
T38829 15530-15538 SP_7 denotes COVID-19
T31712 15591-15595 UBERON:0000033 denotes head
T92434 15632-15647 GO:0050817 denotes anticoagulation
T94628 15709-15721 UBERON:0001016 denotes neurological
T83689 15904-15912 UBERON:0001851 denotes cortical
T14418 16180-16188 SP_7 denotes COVID-19
T83659 16566-16578 UBERON:0001016 denotes neurological
T4245 16813-16821 SP_7 denotes COVID-19
T58751 16839-16854 GO:0050817 denotes anticoagulation
T61381 17018-17026 SP_7 denotes COVID-19
T14339 17174-17189 GO:0050817 denotes anticoagulation
T72313 17220-17228 SP_7 denotes COVID-19
T13917 17302-17317 GO:0050817 denotes anticoagulation
T96601 17322-17330 SP_7 denotes COVID-19

LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 4782-4789 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T2 4782-4789 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T3 10555-10562 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 10555-10562 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 11785-11792 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T6 11785-11792 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T7 12077-12084 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T8 12077-12084 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 4115-4120 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T2 4782-4789 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T3 6742-6750 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T4 7420-7425 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T5 7458-7473 Body_part denotes Coronary artery http://purl.org/sig/ont/fma/fma49893
T6 7674-7679 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T7 8032-8037 Body_part denotes Brain http://purl.org/sig/ont/fma/fma50801
T8 8137-8146 Body_part denotes brainstem http://purl.org/sig/ont/fma/fma79876
T9 8403-8411 Body_part denotes Platelet http://purl.org/sig/ont/fma/fma62851
T10 9769-9777 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T11 10555-10562 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T12 11785-11792 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T13 12077-12084 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T14 12670-12675 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T15 13325-13331 Body_part denotes cortex http://purl.org/sig/ont/fma/fma61109
T16 15591-15595 Body_part denotes head http://purl.org/sig/ont/fma/fma7154
T17 15665-15671 Body_part denotes mental http://purl.org/sig/ont/fma/fma264279

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 4115-4120 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T2 7420-7425 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T3 7458-7473 Body_part denotes Coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T4 7467-7473 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T5 7674-7679 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T6 8032-8037 Body_part denotes Brain http://purl.obolibrary.org/obo/UBERON_0000955
T7 8137-8146 Body_part denotes brainstem http://purl.obolibrary.org/obo/UBERON_0002298
T8 12670-12675 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T9 13325-13331 Body_part denotes cortex http://purl.obolibrary.org/obo/UBERON_0001851
T10 15591-15595 Body_part denotes head http://purl.obolibrary.org/obo/UBERON_0000033

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T15 1553-1556 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T1 12-18 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T3 42-50 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 102-129 Disease denotes Coronavirus Disease of 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T5 131-139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 362-385 Disease denotes intracranial hemorrhage http://purl.obolibrary.org/obo/MONDO_0005049
T7 387-390 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T8 480-488 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 518-521 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T10 626-634 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 664-667 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T12 980-988 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 1012-1015 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T14 1235-1238 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T16 1640-1648 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 1668-1671 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T18 1797-1824 Disease denotes Coronavirus Disease of 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T19 1826-1834 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 1892-1900 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 1966-1988 Disease denotes venous thromboembolism http://purl.obolibrary.org/obo/MONDO_0005399
T22 1990-1993 Disease denotes VTE http://purl.obolibrary.org/obo/MONDO_0005399
T23 2036-2044 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 2228-2231 Disease denotes VTE http://purl.obolibrary.org/obo/MONDO_0005399
T25 2565-2588 Disease denotes intracranial hemorrhage http://purl.obolibrary.org/obo/MONDO_0005049
T26 2590-2593 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T27 2658-2661 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T28 2832-2835 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T29 2891-2899 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T30 2940-2948 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 2976-2986 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T32 3100-3106 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T34 3110-3118 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T35 3151-3154 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T36 3172-3180 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 3237-3240 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T38 3257-3265 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T39 3472-3480 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 4087-4093 Disease denotes trauma http://purl.obolibrary.org/obo/MONDO_0021178
T41 4150-4155 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T42 4249-4257 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 4661-4683 Disease denotes venous thromboembolism http://purl.obolibrary.org/obo/MONDO_0005399
T44 5276-5282 Disease denotes Stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T46 5581-5584 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T47 6014-6022 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 6046-6049 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T49 6125-6128 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T50 6474-6477 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T51 6953-6976 Disease denotes intracranial hemorrhage http://purl.obolibrary.org/obo/MONDO_0005049
T52 7409-7433 Disease denotes Congestive heart failure http://purl.obolibrary.org/obo/MONDO_0005009
T53 7420-7433 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T54 7458-7481 Disease denotes Coronary artery disease http://purl.obolibrary.org/obo/MONDO_0005010
T55 7467-7481 Disease denotes artery disease http://purl.obolibrary.org/obo/MONDO_0000473
T56 7510-7518 Disease denotes Diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T57 7548-7562 Disease denotes Hyperlipidemia http://purl.obolibrary.org/obo/MONDO_0021187
T58 7593-7605 Disease denotes Hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T59 7636-7650 Disease denotes Hypothyroidism http://purl.obolibrary.org/obo/MONDO_0005420
T60 7674-7687 Disease denotes Liver disease http://purl.obolibrary.org/obo/MONDO_0005154
T61 7760-7766 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T63 7790-7803 Disease denotes Renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T65 7969-7972 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T66 8047-8061 Disease denotes Encephalopathy http://purl.obolibrary.org/obo/MONDO_0005560
T67 8266-8273 Disease denotes Aphasia http://purl.obolibrary.org/obo/MONDO_0000598
T68 8373-8376 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T69 8427-8430 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T70 8665-8668 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T71 8752-8755 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T72 8830-8833 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T73 8917-8920 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T74 9337-9340 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T75 9751-9767 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T76 10193-10216 Disease denotes intracranial hemorrhage http://purl.obolibrary.org/obo/MONDO_0005049
T77 10835-10843 Disease denotes Thrombus http://purl.obolibrary.org/obo/MONDO_0000831
T78 11634-11642 Disease denotes thrombus http://purl.obolibrary.org/obo/MONDO_0000831
T79 12077-12109 Disease denotes heparin-induced thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0018048
T80 12093-12109 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T81 12111-12114 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T82 12156-12159 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T83 12380-12383 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T84 12467-12470 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T85 12659-12665 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T86 12830-12838 Disease denotes thrombus http://purl.obolibrary.org/obo/MONDO_0000831
T87 13176-13179 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T88 13227-13233 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T90 13265-13268 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T91 13822-13830 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 13878-13896 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T93 14005-14008 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T94 14165-14173 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 14211-14214 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T96 14465-14473 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 14513-14531 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T98 14653-14676 Disease denotes intracranial hemorrhage http://purl.obolibrary.org/obo/MONDO_0005049
T99 14760-14766 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T101 15138-15148 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T102 15325-15333 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 15530-15538 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 15972-15995 Disease denotes subarachnoid hemorrhage http://purl.obolibrary.org/obo/MONDO_0005099
T105 16083-16086 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T106 16180-16188 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 16218-16221 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T108 16234-16237 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T109 16434-16437 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T110 16731-16734 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T111 16813-16821 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T112 16883-16886 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T113 17018-17026 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 17166-17169 Disease denotes ICH http://purl.obolibrary.org/obo/MONDO_0005049
T115 17220-17228 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T116 17322-17330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 17489-17495 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 430-431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 608-610 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T3 753-754 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 1077-1083 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T5 1178-1179 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 1341-1342 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1480-1482 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T8 1717-1718 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 3506-3508 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T10 3917-3918 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 4115-4120 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T12 4115-4120 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T13 4299-4300 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 4324-4325 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 4988-4990 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T16 5030-5032 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T17 5188-5189 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T18 5708-5709 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 5734-5735 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T20 5777-5778 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T21 6103-6109 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T22 6116-6117 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 6695-6697 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T24 7142-7144 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T25 7314-7320 http://purl.obolibrary.org/obo/UBERON_0003100 denotes Female
T26 7420-7425 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T27 7420-7425 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T28 7420-7425 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T29 7420-7425 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T30 7467-7473 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T31 7467-7473 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T32 7674-7679 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T33 7674-7679 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T34 7889-7891 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T35 8032-8037 http://purl.obolibrary.org/obo/UBERON_0000955 denotes Brain
T36 8032-8037 http://www.ebi.ac.uk/efo/EFO_0000302 denotes Brain
T37 9371-9373 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T38 9807-9808 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T39 10449-10451 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T40 10509-10511 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T41 10805-10807 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T42 10959-10961 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T43 11417-11419 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T44 11505-11507 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T45 11613-11614 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 11664-11666 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T47 12145-12151 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T48 12225-12227 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T49 12284-12285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 12670-12675 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T51 12670-12675 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T52 12689-12690 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 12791-12792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 12822-12823 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 12894-12896 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T56 13325-13331 http://purl.obolibrary.org/obo/UBERON_0001851 denotes cortex
T57 13385-13386 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 14402-14403 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 15281-15284 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T60 15579-15580 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 15591-15595 http://purl.obolibrary.org/obo/UBERON_0000033 denotes head
T62 15591-15595 http://www.ebi.ac.uk/efo/EFO_0000964 denotes head
T63 15702-15703 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 16141-16144 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T65 16291-16294 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T66 16368-16369 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T67 16555-16556 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 16605-16606 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 17472-17473 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T70 17603-17606 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T71 17617-17618 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 4782-4789 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T2 4807-4817 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T3 7371-7373 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T4 8817-8820 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088
T5 9548-9556 Chemical denotes warfarin http://purl.obolibrary.org/obo/CHEBI_10033
T6 9561-9571 Chemical denotes dabigatran http://purl.obolibrary.org/obo/CHEBI_70752
T7 10401-10404 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088
T8 10555-10562 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T9 10575-10585 Chemical denotes Enoxaparin http://purl.obolibrary.org/obo/CHEBI_28304
T10 10987-10994 Chemical denotes Aspirin http://purl.obolibrary.org/obo/CHEBI_15365
T11 11027-11034 Chemical denotes Aspirin http://purl.obolibrary.org/obo/CHEBI_15365
T12 11039-11050 Chemical denotes clopidogrel http://purl.obolibrary.org/obo/CHEBI_37941
T13 11785-11792 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T14 11885-11895 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T15 12077-12084 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T16 12350-12353 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088
T17 12995-12998 Chemical denotes PTT http://purl.obolibrary.org/obo/CHEBI_3088

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 2068-2079 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T2 4553-4574 http://purl.obolibrary.org/obo/GO_0003094 denotes glomerular filtration
T3 4581-4585 http://purl.obolibrary.org/obo/GO_0005006 denotes eGFR
T4 6585-6606 http://purl.obolibrary.org/obo/GO_0003094 denotes glomerular filtration
T5 6613-6617 http://purl.obolibrary.org/obo/GO_0005006 denotes eGFR
T6 8355-8359 http://purl.obolibrary.org/obo/GO_0005006 denotes eGFR
T7 9151-9172 http://purl.obolibrary.org/obo/GO_0003094 denotes glomerular filtration
T8 12024-12028 http://purl.obolibrary.org/obo/GO_0005006 denotes eGFR
T9 16623-16632 http://purl.obolibrary.org/obo/GO_0006810 denotes transport

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 0-18 Phenotype denotes Hemorrhagic stroke http://purl.obolibrary.org/obo/HP_0001342
T2 362-385 Phenotype denotes intracranial hemorrhage http://purl.obolibrary.org/obo/HP_0002170
T3 387-390 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T4 518-521 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T5 664-667 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T6 1012-1015 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T7 1235-1238 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T8 1553-1556 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T9 1668-1671 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T10 1973-1988 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T11 2565-2588 Phenotype denotes intracranial hemorrhage http://purl.obolibrary.org/obo/HP_0002170
T12 2590-2593 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T13 2658-2661 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T14 2832-2835 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T15 3091-3106 Phenotype denotes ischemic stroke http://purl.obolibrary.org/obo/HP_0002140
T16 3151-3154 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T17 3237-3240 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T18 4103-4120 Phenotype denotes bleeding in brain http://purl.obolibrary.org/obo/HP_0001342
T19 4150-4155 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T20 4668-4683 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T21 5276-5282 Phenotype denotes Stroke http://purl.obolibrary.org/obo/HP_0001297
T22 5581-5584 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T23 6046-6049 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T24 6125-6128 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T25 6474-6477 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T26 6953-6976 Phenotype denotes intracranial hemorrhage http://purl.obolibrary.org/obo/HP_0002170
T27 7409-7433 Phenotype denotes Congestive heart failure http://purl.obolibrary.org/obo/HP_0001635
T28 7548-7562 Phenotype denotes Hyperlipidemia http://purl.obolibrary.org/obo/HP_0003077
T29 7593-7605 Phenotype denotes Hypertension http://purl.obolibrary.org/obo/HP_0000822
T30 7636-7650 Phenotype denotes Hypothyroidism http://purl.obolibrary.org/obo/HP_0000821
T31 7674-7687 Phenotype denotes Liver disease http://purl.obolibrary.org/obo/HP_0001392
T32 7760-7766 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T33 7969-7972 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T34 8047-8061 Phenotype denotes Encephalopathy http://purl.obolibrary.org/obo/HP_0001298
T35 8221-8228 Phenotype denotes Seizure http://purl.obolibrary.org/obo/HP_0001250
T36 8266-8273 Phenotype denotes Aphasia http://purl.obolibrary.org/obo/HP_0002381
T37 8373-8376 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T38 8427-8430 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T39 8665-8668 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T40 8752-8755 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T41 8830-8833 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T42 8917-8920 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T43 9337-9340 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T44 9751-9767 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T45 10193-10216 Phenotype denotes intracranial hemorrhage http://purl.obolibrary.org/obo/HP_0002170
T46 10788-10804 Phenotype denotes Elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T47 11529-11545 Phenotype denotes elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T48 12077-12109 Phenotype denotes heparin-induced thrombocytopenia http://purl.obolibrary.org/obo/HP_0011874
T49 12111-12114 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T50 12156-12159 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T51 12380-12383 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T52 12467-12470 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T53 12670-12684 Phenotype denotes brain swelling http://purl.obolibrary.org/obo/HP_0002181
T54 13176-13179 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T55 13218-13233 Phenotype denotes ischemic stroke http://purl.obolibrary.org/obo/HP_0002140
T56 13265-13268 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T57 13878-13896 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724
T58 14005-14008 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T59 14211-14214 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T60 14366-14382 Phenotype denotes elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T61 14513-14531 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724
T62 14653-14676 Phenotype denotes intracranial hemorrhage http://purl.obolibrary.org/obo/HP_0002170
T63 14751-14766 Phenotype denotes ischemic stroke http://purl.obolibrary.org/obo/HP_0002140
T64 15357-15373 Phenotype denotes elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T65 15972-15995 Phenotype denotes subarachnoid hemorrhage http://purl.obolibrary.org/obo/HP_0002138
T66 16083-16086 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T67 16218-16221 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T68 16234-16237 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T69 16434-16437 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T70 16731-16734 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T71 16883-16886 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T72 17166-17169 Phenotype denotes ICH http://purl.obolibrary.org/obo/HP_0002170
T73 17489-17495 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-50 Sentence denotes Hemorrhagic stroke and anticoagulation in COVID-19
T2 52-60 Sentence denotes Abstract
T3 61-83 Sentence denotes Background and Purpose
T4 84-199 Sentence denotes Patients with the Coronavirus Disease of 2019 (COVID-19) are at increased risk for thrombotic events and mortality.
T5 200-277 Sentence denotes Various anticoagulation regimens are now being considered for these patients.
T6 278-418 Sentence denotes Anticoagulation is known to increase the risk for adverse bleeding events, of which intracranial hemorrhage (ICH) is one of the most feared.
T7 419-573 Sentence denotes We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population.
T8 575-582 Sentence denotes Methods
T9 583-696 Sentence denotes Patients over the age of 18 with confirmed COVID-19 and radiographic evidence of ICH were included in this study.
T10 697-791 Sentence denotes Evidence of hemorrhage was confirmed and categorized by a fellowship trained neuroradiologist.
T11 792-953 Sentence denotes Electronic health records were analyzed for patient information including demographic data, medical history, hospital course, laboratory values, and medications.
T12 955-962 Sentence denotes Results
T13 963-1084 Sentence denotes We identified 33 COVID-19 positive patients with ICH, mean age 61.6 years (range 37–83 years), 21.2% of whom were female.
T14 1085-1200 Sentence denotes Parenchymal hemorrhages with mass effect and herniation occurred in 5 (15.2%) patients, with a 100% mortality rate.
T15 1201-1406 Sentence denotes Of the remaining 28 patients with ICH, 7 (25%) had punctate hemorrhages, 17 (60.7%) had small- moderate size hemorrhages, and 4 (14.3%) had a large single site of hemorrhage without evidence of herniation.
T16 1407-1567 Sentence denotes Almost all patients received either therapeutic dose anticoagulation (in 22 [66.7%] patients) or prophylactic dose (in 3 [9.1] patients) prior to ICH discovery.
T17 1569-1580 Sentence denotes Conclusions
T18 1581-1737 Sentence denotes Anticoagulation therapy may be considered in patients with COVID-19 though the risk of ICH should be taken into account when developing a treatment regimen.
T19 1739-1751 Sentence denotes Introduction
T20 1752-2459 Sentence denotes Recent studies have shown that patients with Coronavirus Disease of 2019 (COVID-19) are predisposed to developing thrombotic events.1, 2, 3 COVID-19 patients in intensive care units (ICU) have an increased rate of venous thromboembolism (VTE), ranging from 17% to 25%.1 , 2 Moreover, COVID-19 patients have elevated coagulation markers such as D-dimer, which in turn is correlated with increased mortality.3 Recent expert opinion recommends that all admitted patients receive VTE prophylaxis, but some centers have escalated their anticoagulation regimen for patients with certain risk factors.4 Some ICU centers have also begun to empirically use therapeutic anticoagulation for presumed pulmonary emboli.4
T21 2460-2609 Sentence denotes The greatest concern of increased anticoagulation use is an increased risk of bleeding in general and of intracranial hemorrhage (ICH) in particular.
T22 2610-3341 Sentence denotes In studies of patients on oral anticoagulation, ICH was shown to be the most devastating adverse event overall; these patients also had more extensive bleeding and increased mortality compared to patients with spontaneous ICH.5 , 6 While information on bleeding remains limited in COVID-19 patients, one study suggested that many COVID-19 patients with high risk of thrombosis were simultaneously at increased risk for bleeding.7 Although there have been recent publications about ischemic stroke in COVID-19 patients,1 literature regarding ICH in patients with COVID-19 is currently limited.8 , 9 We evaluated the presence of ICH in hospitalized COVID-19 patients and correlated imaging findings with their anticoagulation status.
T23 3343-3364 Sentence denotes Materials and methods
T24 3365-3459 Sentence denotes This cohort study was approved by the Institutional Review Board with informed consent waived.
T25 3460-3737 Sentence denotes Out of 3824 COVID-19 positive adult (age over 18) patients admitted to the NYU Langone Health system (Tisch Hospital, Kimmel Pavilion, NYU Brooklyn, NYU Winthrop, or NYU Langone Orthopedic Hospital) between March 1st and April 27th, 2020, neuroimaging was done in 755 patients.
T26 3738-3868 Sentence denotes After reviewing the neuroimaging reports for these patients, 37 were found to have documented radiographic evidence of hemorrhage.
T27 3869-4040 Sentence denotes Neuroimaging for these patients was reviewed by a fellowship-trained neuroradiologist, blinded to clinical data and outcome, to verify the presence and type of hemorrhage.
T28 4041-4188 Sentence denotes Four patients who had hemorrhage secondary to trauma (n = 2), bleeding in brain metastases (n = 1), or after tumor resection (n = 1) were excluded.
T29 4189-4340 Sentence denotes Of the 33 remaining patients (4.4% of the 755 patients with COVID-19 diagnoses and neuroimaging), 24 had only a CT scan and 9 had both a CT and an MRI.
T30 4341-4704 Sentence denotes Electronic health records of all patients with verified hemorrhage were then examined in order to review demographic data, medical history, hospital course, medications, and laboratory values including estimated glomerular filtration rate (eGFR) due to associations between impaired renal function and increased risk of venous thromboembolism as well as bleeding.
T31 4705-5063 Sentence denotes Therapeutic anticoagulation for our cohort was classified as any intravenous heparin, any intravenous argatroban, or enoxaparin dose above prophylactic levels (40mg subcutaneously daily or 30mg subcutaneously twice daily for BMI <40; 40mg subcutaneously twice daily for BMI>40).10 , 11 The closest D-dimer to the scan within 48 hours of imaging was recorded.
T32 5064-5187 Sentence denotes Follow-up was performed through May 6th, 2020 to track mortality, continued hospitalization, or discharge for all patients.
T33 5188-5625 Sentence denotes A modified version of the classification system used for the European Cooperative Acute Stroke Study was used to classify hemorrhages as infarct with petechial hemorrhage, infarct with small hemorrhage (<5 cm), single site of large parenchymal hemorrhage with local mass effect but without herniation, and multiple sites of parenchymal hemorrhages with mass effect and herniation (Fig. 1 ).12 ICH Score was calculated for all patients.13
T34 5626-5935 Sentence denotes Fig. 1 CT images of four different patients demonstrating petechial hemorrhage in a small cortical infarct (A), infarct with small hemorrhage (<5 cm) (B), single site of large parenchymal hemorrhage with local mass effect (C), and multiple sites of parenchymal hemorrhages with mass effect and herniation (D).
T35 5937-5944 Sentence denotes Results
T36 5946-5996 Sentence denotes Patient demographics and pertinent laboratory data
T37 5997-6183 Sentence denotes We identified 33 COVID-19 positive patients with ICH, mean age 61.6 years (range 37–83 years), 21.2% were female, with a median ICH score of 2 (interquartile range [IQR] 1-2) (Table 1 ).
T38 6184-6336 Sentence denotes As of May 6th, 2020, mortality occurred in 14 (42.4%) patients, 15 (45.5%) patients were still hospitalized, and 4 (12.1%) patients had been discharged.
T39 6337-6502 Sentence denotes Initial radiographic evidence of hemorrhage was seen on median hospital day 17 (IQR 8-23) although 4 (12.1%) patients were found to have ICH on initial presentation.
T40 6503-6643 Sentence denotes Immediately prior to discovery of the bleed, 10 (30.3%) patients had an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m2.
T41 6644-6776 Sentence denotes Within the 72 hours prior to hemorrhage discovery, 11 (33.3%) patients were thrombocytopenic with platelet counts below 150 × 103/μ.
T42 6777-6869 Sentence denotes The median D-dimer value prior to hemorrhage discovery was 2204 ng/mL (IQR 1232–3074 ng/mL).
T43 6870-6977 Sentence denotes Table 1 Demographic, admission, imaging, and laboratory data for all patients with intracranial hemorrhage.
T44 6978-7032 Sentence denotes Data is presented as n (%) unless otherwise specified.
T45 7033-7158 Sentence denotes Lab values are within 72 h prior to hemorrhage discovery, besides D-dimer, which is the closest value within 48 h of imaging.
T46 7159-7251 Sentence denotes Parameter Total (n = 33) Large hemorrhage with herniation (n = 5) Other hemorrhages (n = 28)
T47 7252-7313 Sentence denotes Age, median (range) in years 62 (37–83) 62 (37–74) 62 (40–83)
T48 7314-7344 Sentence denotes Female 7 (21.2) 0 (0) 7 (25.0)
T49 7345-7358 Sentence denotes Comorbidities
T50 7359-7407 Sentence denotes  BMI, mean (SD) 28.9 (5.6) 32.9 (9.0) 28.1 (4.6)
T51 7408-7456 Sentence denotes  Congestive heart failure 3 (9.1) 0 (0) 3 (10.7)
T52 7457-7508 Sentence denotes  Coronary artery disease 4 (12.1) 1 (20.0) 3 (10.7)
T53 7509-7546 Sentence denotes  Diabetes 10 (30.3) 2 (40.0) 8 (28.6)
T54 7547-7591 Sentence denotes  Hyperlipidemia 12 (36.4) 2 (40.0) 10 (35.7)
T55 7592-7634 Sentence denotes  Hypertension 16 (48.5) 3 (60.0) 13 (46.4)
T56 7635-7672 Sentence denotes  Hypothyroidism 2 (6.1) 0 (0) 2 (7.1)
T57 7673-7709 Sentence denotes  Liver disease 1 (3.0) 0 (0) 1 (3.6)
T58 7710-7752 Sentence denotes  Prior malignancy 3 (9.1) 2 (40.0) 1 (3.6)
T59 7753-7788 Sentence denotes  Prior stroke 1 (3.0) 0 (0) 1 (3.6)
T60 7789-7825 Sentence denotes  Renal disease 1 (3.0) 0 (0) 1 (3.6)
T61 7826-7909 Sentence denotes Time to Hemorrhage Identification, median days (IQR) 17 (8–23) 22 (19–28) 16 (8–33)
T62 7910-7968 Sentence denotes GCS at time of Scan, median (IQR) 3 (3–9) 3 (3-3) 3 (3–10)
T63 7969-8016 Sentence denotes ICH Score, median (IQR) 2 (1-2) 5 (5-5) 2 (1-2)
T64 8017-8045 Sentence denotes Indication for Brain Imaging
T65 8046-8088 Sentence denotes  Encephalopathy 17 (51.5) 1 (20) 16 (57.1)
T66 8089-8128 Sentence denotes  Focal weakness 7 (21.2) 0 (0) 7 (25.0)
T67 8129-8177 Sentence denotes  Absent brainstem reflexes 4 (12.1) 4 (80) 0 (0)
T68 8178-8219 Sentence denotes  Incidental finding 2 (6.1) 0 (0) 2 (7.1)
T69 8220-8264 Sentence denotes  Seizure like symptoms 2 (6.1) 0 (0) 2 (7.1)
T70 8265-8295 Sentence denotes  Aphasia 1 (3.0) 0 (0) 1 (3.6)
T71 8296-8354 Sentence denotes Hemorrhage on initial presentation 4 (12.1) 0 (0) 4 (14.3)
T72 8355-8402 Sentence denotes eGFR <30 prior to ICH 10 (30.3) 2 (40) 8 (28.6)
T73 8403-8486 Sentence denotes Platelet nadir prior to ICH, median [IQR] 200 (123–270) 147 (123–187) 227 (118–274)
T74 8487-8551 Sentence denotes  Nadir 100 to 149, n (range) 4 (101–147) 2 (123–147) 2 (101–124)
T75 8552-8605 Sentence denotes  Nadir 50 to 99, n (range) 6 (50–97) 1 (50) 5 (51–97)
T76 8606-8647 Sentence denotes  Nadir 0 to 49, n (range) 1 (15) 0 1 (15)
T77 8648-8733 Sentence denotes D-dimer prior to ICH, median (IQR) 2204 (1232–3074) 2069 (1791–4488) 2338 (1209–3030)
T78 8734-8811 Sentence denotes Peak INR prior to ICH, median (IQR) 1.3 (1.2–2.0) 1.6 (1.3–2.9) 1.3 (1.2–1.7)
T79 8812-8899 Sentence denotes Peak PTT prior to ICH, median (IQR) 77.0 (42.2–96.2) 86.1 (66.8–121.4) 75.1 (41.7–85.8)
T80 8900-8976 Sentence denotes Peak Xa prior to ICH, median (IQR) 0.7 (0.4–1.0) 1.1 (1.0–1.1) 0.6 (0.3–0.8)
T81 8977-9013 Sentence denotes Mortality 14 (42.4) 5 (100) 9 (32.1)
T82 9014-9253 Sentence denotes Abbreviations: SD = standard deviation; IQR =interquartile range; BMI = body mass index; ICH = intracranial hemorrhage; eGFR = estimated glomerular filtration fraction; INR: international normalized ratio; PTT = partial thromboplastin time
T83 9255-9294 Sentence denotes Anticoagulation and antiplatelet status
T84 9295-9402 Sentence denotes Therapeutic dose anticoagulation prior to ICH discovery was administered to 22 (66.7%) patients (Table 2 ).
T85 9403-9475 Sentence denotes Prophylactic dose anticoagulation was administered to 3 (9.1%) patients.
T86 9476-9599 Sentence denotes Two (6.1%) patients who presented with hemorrhage had been on long-term warfarin and dabigatran at home prior to admission.
T87 9600-9908 Sentence denotes Six (18.2%) patients never received anticoagulation either before or during their hospitalization; three were on antiplatelet medication only, two had thrombocytopenia (platelet count <75 on admission), and a sixth presented with systemic hemorrhage of unknown etiology and thus anticoagulation was withheld.
T88 9909-10121 Sentence denotes Six (27.3%) patients received concurrent inpatient therapeutic anticoagulation and antiplatelet therapy, and one (4.5%) patient received concurrent inpatient prophylactic anticoagulation and antiplatelet therapy.
T89 10122-10217 Sentence denotes Table 2 Anticoagulation and antiplatelet therapy for all patients with intracranial hemorrhage.
T90 10218-10272 Sentence denotes Data is presented as n (%) unless otherwise specified.
T91 10273-10365 Sentence denotes Parameter Total (n = 33) Large hemorrhage with herniation (n = 5) Other hemorrhages (n = 28)
T92 10366-10458 Sentence denotes Supratherapeutic anti-factor Xa or PTT within 72 h prior to bleed 15 (45.5) 4 (80) 11 (39.3)
T93 10459-10490 Sentence denotes Anticoagulation prior to bleed*
T94 10491-10538 Sentence denotes  Therapeutic dose 22 (66.7) 5 (100.0) 17 (60.7)
T95 10539-10573 Sentence denotes  Unfractionated heparin, n 21 5 16
T96 10574-10594 Sentence denotes  Enoxaparin, n 4 0 4
T97 10595-10615 Sentence denotes  Argatroban, n 3 0 3
T98 10616-10657 Sentence denotes  Prophylactic dose 3 (9.1) 0 (0) 3 (10.7)
T99 10658-10715 Sentence denotes  Anticoagulation prior to admission 2 (6.1) 0 (0) 2 (7.1)
T100 10716-10745 Sentence denotes  None 6 (18.2) 0 (0) 6 (21.4)
T101 10746-10786 Sentence denotes Indication for Inpatient Anticoagulation
T102 10787-10833 Sentence denotes  Elevated D-dimer 18 (72.0) 3 (60.0) 15 (75.0)
T103 10834-10870 Sentence denotes  Thrombus 4 (16.0) 2 (40.0) 2 (10.0)
T104 10871-10916 Sentence denotes  Standard prophylaxis 3 (12.0) 0 (0) 3 (15.0)
T105 10917-10952 Sentence denotes Antiplatelet therapy prior to bleed
T106 10953-10985 Sentence denotes  None 22 (66.7) 3 (60) 19 (67.9)
T107 10986-11025 Sentence denotes  Aspirin alone 7 (21.2) 1 (20) 6 (21.4)
T108 11026-11072 Sentence denotes  Aspirin and clopidogrel 2 (6.1) 0 (0) 2 (7.1)
T109 11073-11112 Sentence denotes  Cilostazol alone 1 (3.0) 0 (0) 1 (3.6)
T110 11113-11154 Sentence denotes  Clopidogrel alone 1 (3.0) 1 (20) 0 (0.0)
T111 11155-11373 Sentence denotes ⁎ Therapeutic dose numbers sum to more than the number of patients receiving therapeutic anticoagulation as patients received multiple types of therapeutic anticoagulation at different periods of their hospitalization.
T112 11375-11409 Sentence denotes Therapeutic anticoagulation cohort
T113 11410-11653 Sentence denotes Of the 22 patients that were on therapeutic anticoagulation as an inpatient, the indication in 18 (81.8%) patients was elevated D-dimer levels (median 3493 ng/mL, IQR 2468–9296 ng/ml), and 4 (18.2%) had a known or suspected thrombus (Table 2).
T114 11654-11732 Sentence denotes For these 22 patients, the therapeutic anticoagulation regimen was as follows:
T115 11733-11954 Sentence denotes 15 (68.2%) received only intravenous unfractionated heparin (UFH), 3 (13.6%) received UFH and enoxaparin at different times, 3 (13.6%) received UFH and argatroban at different times, and 1 (4.5%) received only enoxaparin.
T116 11955-12029 Sentence denotes Changes between UFH and enoxaparin and vice versa were made based on eGFR.
T117 12030-12217 Sentence denotes Argatroban was used when there was concern for heparin-induced thrombocytopenia (HIT); however, four patients were tested for HIT antibodies, and all were eventually noted to be negative.
T118 12218-12384 Sentence denotes Of the 22 patients on therapeutic anticoagulation, 12 (54.5%) had a supratherapeutic anti-factor Xa or partial thromboplastin time (PTT) within 72 h prior to the ICH.
T119 12386-12442 Sentence denotes Types of parenchymal hemorrhage and clinical correlation
T120 12443-12542 Sentence denotes Of the 33 patients with ICH, 5 (15.2%) had parenchymal hemorrhages with mass effect and herniation.
T121 12543-12721 Sentence denotes These images were particularly notable as all 5 patients also had radiographic evidence of diffuse hypoxic ischemic injury and brain swelling and a 100% mortality rate (Table 1).
T122 12722-12839 Sentence denotes All 5 patients had received therapeutic anticoagulation, 3 (60%) for a high D-dimer and 2 (40%) for a known thrombus.
T123 12840-12928 Sentence denotes Imaging evidence of hemorrhage was seen on median day 22 (IQR 19–28) of hospitalization.
T124 12929-13076 Sentence denotes Among these 5 patients, 4 (80%) patients had an anti-factor Xa or PTT above the upper limit of normal within 72 hours prior to the bleed (Table 2).
T125 13077-13234 Sentence denotes Based on review by the study neuroradiologist, all of these hemorrhages were thought to be primary ICH rather than hemorrhagic conversion of ischemic stroke.
T126 13235-13460 Sentence denotes Of the other 28 patients with ICH, 7 (25%) had punctate hemorrhages, mostly involving the cortex, 17 (60.7%) had small hemorrhages, and 4 (14.3%) had a large single site of hemorrhage without evidence of herniation (Table 1).
T127 13461-13608 Sentence denotes Based on review by the study neuroradiologist, 26/28 (92.9%) bleeds were considered to have suffered hemorrhagic conversion of an ischemic infarct.
T128 13609-13767 Sentence denotes Mortality was 8/24 (33.3%) of the patients with punctate and small hemorrhages and 1/4 (25%) of the patients with large single hemorrhages without herniation.
T129 13769-13779 Sentence denotes Discussion
T130 13780-13940 Sentence denotes Discussions regarding anticoagulation for COVID-19 patients have been intensifying as evidence of hypercoagulability in this population continues to accumulate.
T131 13941-14054 Sentence denotes Decisions about anticoagulation must, in part, take the risk of ICH following anticoagulation into consideration.
T132 14055-14105 Sentence denotes Our data will certainly be helpful in this regard.
T133 14106-14215 Sentence denotes We found that 4.4% of 755 patients diagnosed with positive COVID-19 and with concurrent neuroimaging had ICH.
T134 14216-14303 Sentence denotes The majority of these patients received therapeutic anticoagulation, most commonly UFH.
T135 14304-14767 Sentence denotes The most frequent indication for starting anticoagulation was elevated D-dimer levels, reflecting a trend among centers to intensify anticoagulation regimens in COVID-19 positive patients based on evidence of hypercoagulability including increased D-dimer.4 Although the large hemorrhages causing herniation were thought to be the result of primary intracranial hemorrhage, the majority of the other hemorrhages were hemorrhagic transformation of ischemic stroke.
T136 14768-14891 Sentence denotes Of particular interest is our subgroup of 5 patients with large parenchymal hemorrhages causing mass effect and herniation.
T137 14892-15037 Sentence denotes Mortality was 100% in these patients, all of whom were on continuous UFH and were found to have hemorrhages many days into their hospitalization.
T138 15038-15247 Sentence denotes Although two of these patients were placed on therapeutic anticoagulation due to known or suspected thrombosis, the other three were started on therapeutic anticoagulation because of increasing D-dimer levels.
T139 15248-15539 Sentence denotes Although empiric anticoagulation has been shown to lower 28-day mortality in COVID-19 patients with severely elevated D-dimer,14 this sobering outcome underscores the need for randomized clinical trials to properly assess benefit versus risk regarding anticoagulation strategies in COVID-19.
T140 15540-15823 Sentence denotes It also raises the question of whether a screening head CT should be done prior to starting anticoagulation in patients with mental status too impaired to obtain a good neurological assessment, so as to avoid the risk of catastrophic hemorrhage in an unsuspected large acute infarct.
T141 15824-16014 Sentence denotes In our study, many patients had punctate hemorrhages that were characterized as cortical in nature on MRI, but that were either mischaracterized as subarachnoid hemorrhage or not seen on CT.
T142 16015-16280 Sentence denotes MRI is known to have better sensitivity than CT for detecting small ICH,15 but as neuroimaging use, and particularly MRI use, has decreased significantly during the COVID-19 pandemic, some patients with ICH may have an ICH that is diagnosed late or missed entirely.
T143 16281-16388 Sentence denotes Our study has multiple limitations, most importantly its descriptive nature as well as a small sample size.
T144 16389-16666 Sentence denotes It is possible that additional patients with ICH in this cohort were not identified either because the patients were heavily sedated and there was no opportunity for a detailed neurological examination and there was a desire to limit transport out of the room for neuroimaging.
T145 16667-16781 Sentence denotes As such, MRI use was limited in this cohort and adjudication of ICH etiology were made to the best of our ability.
T146 16782-16982 Sentence denotes We were not able to review all COVID-19 patients getting anticoagulation to see how many of them had ICH, and we did not include patients with neuroimaging but no hemorrhage in this descriptive paper.
T147 16983-17088 Sentence denotes We did not compare our patients to COVID-19 patients who had neuroimaging without evidence of hemorrhage.
T148 17089-17229 Sentence denotes Nevertheless, we believe our study provides important initial data regarding ICH and anticoagulation in patients hospitalized with COVID-19.
T149 17230-17425 Sentence denotes Future work must look more deeply into the benefits and consequences of anticoagulation for COVID-19 patients, through outcomes analysis and well-powered, prospective, randomized clinical trials.
T150 17427-17460 Sentence denotes Declaration of Competing Interest
T151 17461-17463 Sentence denotes R.
T152 17464-17591 Sentence denotes Jain is a consultant for Cancer Panels Inc., receive royalties from Thieme Inc., and is on the advisory board for Nuevozen Inc.
T153 17592-17594 Sentence denotes S.
T154 17595-17640 Sentence denotes Galetta has served as a consultant to Biogen.
T155 17641-17679 Sentence denotes The other authors report no conflicts.
T156 17681-17696 Sentence denotes Acknowledgments
T157 17697-17850 Sentence denotes We would like to acknowledge the NYU Family Connect Program as well as the thousands of front-line healthcare workers as an inspiration for this project.
T158 17852-17859 Sentence denotes Funding
T159 17860-17865 Sentence denotes None.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 0-18 Disease denotes Hemorrhagic stroke MESH:D020521
3 42-50 Disease denotes COVID-19 MESH:C000657245
16 84-92 Species denotes Patients Tax:9606
17 458-466 Species denotes patients Tax:9606
18 268-276 Species denotes patients Tax:9606
19 102-129 Disease denotes Coronavirus Disease of 2019 MESH:C000657245
20 131-139 Disease denotes COVID-19 MESH:C000657245
21 167-177 Disease denotes thrombotic MESH:D013927
22 189-198 Disease denotes mortality MESH:D003643
23 328-344 Disease denotes adverse bleeding MESH:D006470
24 362-385 Disease denotes intracranial hemorrhage MESH:D020300
25 387-390 Disease denotes ICH MESH:D002543
26 480-488 Disease denotes COVID-19 MESH:C000657245
27 518-521 Disease denotes ICH MESH:D002543
33 583-591 Species denotes Patients Tax:9606
34 836-843 Species denotes patient Tax:9606
35 626-634 Disease denotes COVID-19 MESH:C000657245
36 664-667 Disease denotes ICH MESH:D002543
37 709-719 Disease denotes hemorrhage MESH:D006470
53 998-1006 Species denotes patients Tax:9606
54 1163-1171 Species denotes patients Tax:9606
55 1221-1229 Species denotes patients Tax:9606
56 1418-1426 Species denotes patients Tax:9606
57 1491-1499 Species denotes patients Tax:9606
58 1534-1542 Species denotes patients Tax:9606
59 980-988 Disease denotes COVID-19 MESH:C000657245
60 1012-1015 Disease denotes ICH MESH:D002543
61 1097-1108 Disease denotes hemorrhages MESH:D006470
62 1185-1194 Disease denotes mortality MESH:D003643
63 1235-1238 Disease denotes ICH MESH:D002543
64 1261-1272 Disease denotes hemorrhages MESH:D006470
65 1310-1321 Disease denotes hemorrhages MESH:D006470
66 1364-1374 Disease denotes hemorrhage MESH:D006470
67 1553-1556 Disease denotes ICH MESH:D002543
71 1626-1634 Species denotes patients Tax:9606
72 1640-1648 Disease denotes COVID-19 MESH:C000657245
73 1668-1671 Disease denotes ICH MESH:D002543
89 1783-1791 Species denotes patients Tax:9606
90 1901-1909 Species denotes patients Tax:9606
91 2045-2053 Species denotes patients Tax:9606
92 2211-2219 Species denotes patients Tax:9606
93 2311-2319 Species denotes patients Tax:9606
94 1797-1824 Disease denotes Coronavirus Disease of 2019 MESH:C000657245
95 1826-1834 Disease denotes COVID-19 MESH:C000657245
96 1866-1876 Disease denotes thrombotic MESH:D013927
97 1892-1900 Disease denotes COVID-19 MESH:C000657245
98 1966-1988 Disease denotes venous thromboembolism MESH:D054556
99 1990-1993 Disease denotes VTE MESH:D054556
100 2036-2044 Disease denotes COVID-19 MESH:C000657245
101 2148-2157 Disease denotes mortality MESH:D003643
102 2228-2231 Disease denotes VTE MESH:D054556
103 2441-2457 Disease denotes pulmonary emboli MESH:D011655
130 2624-2632 Species denotes patients Tax:9606
131 2728-2736 Species denotes patients Tax:9606
132 2806-2814 Species denotes patients Tax:9606
133 2900-2908 Species denotes patients Tax:9606
134 2949-2957 Species denotes patients Tax:9606
135 3119-3127 Species denotes patients Tax:9606
136 3158-3166 Species denotes patients Tax:9606
137 3266-3274 Species denotes patients Tax:9606
138 2538-2546 Disease denotes bleeding MESH:D006470
139 2565-2588 Disease denotes intracranial hemorrhage MESH:D020300
140 2590-2593 Disease denotes ICH MESH:D002543
141 2658-2661 Disease denotes ICH MESH:D002543
142 2761-2769 Disease denotes bleeding MESH:D006470
143 2784-2793 Disease denotes mortality MESH:D003643
144 2832-2835 Disease denotes ICH MESH:D002543
145 2863-2871 Disease denotes bleeding MESH:D006470
146 2891-2899 Disease denotes COVID-19 MESH:C000657245
147 2940-2948 Disease denotes COVID-19 MESH:C000657245
148 2976-2986 Disease denotes thrombosis MESH:D013927
149 3029-3037 Disease denotes bleeding MESH:D006470
150 3091-3106 Disease denotes ischemic stroke MESH:D002544
151 3110-3118 Disease denotes COVID-19 MESH:C000657245
152 3151-3154 Disease denotes ICH MESH:D002543
153 3172-3180 Disease denotes COVID-19 MESH:C000657245
154 3237-3240 Disease denotes ICH MESH:D002543
155 3257-3265 Disease denotes COVID-19 MESH:C000657245
161 3510-3518 Species denotes patients Tax:9606
162 3728-3736 Species denotes patients Tax:9606
163 3789-3797 Species denotes patients Tax:9606
164 3472-3480 Disease denotes COVID-19 MESH:C000657245
165 3857-3867 Disease denotes hemorrhage MESH:D006470
177 3892-3900 Species denotes patients Tax:9606
178 4046-4054 Species denotes patients Tax:9606
179 4209-4217 Species denotes patients Tax:9606
180 4235-4243 Species denotes patients Tax:9606
181 4029-4039 Disease denotes hemorrhage MESH:D006470
182 4063-4073 Disease denotes hemorrhage MESH:D006470
183 4087-4093 Disease denotes trauma MESH:D014947
184 4103-4111 Disease denotes bleeding MESH:D006470
185 4115-4131 Disease denotes brain metastases MESH:D009362
186 4150-4155 Disease denotes tumor MESH:D009369
187 4249-4257 Disease denotes COVID-19 MESH:C000657245
197 4374-4382 Species denotes patients Tax:9606
198 5178-5186 Species denotes patients Tax:9606
199 4782-4789 Chemical denotes heparin MESH:D006493
200 4807-4817 Chemical denotes argatroban MESH:C031942
201 4822-4832 Chemical denotes enoxaparin MESH:D017984
202 4397-4407 Disease denotes hemorrhage MESH:D006470
203 4661-4683 Disease denotes venous thromboembolism MESH:D054556
204 4695-4703 Disease denotes bleeding MESH:D006470
205 5119-5128 Disease denotes mortality MESH:D003643
213 5661-5669 Species denotes patients Tax:9606
214 5694-5704 Disease denotes hemorrhage MESH:D006470
215 5725-5732 Disease denotes infarct MESH:D007238
216 5738-5745 Disease denotes infarct MESH:D007238
217 5751-5767 Disease denotes small hemorrhage MESH:D006470
218 5814-5824 Disease denotes hemorrhage MESH:D006470
219 5875-5898 Disease denotes parenchymal hemorrhages MESH:D002543
230 5614-5622 Species denotes patients Tax:9606
231 5276-5282 Disease denotes Stroke MESH:D020521
232 5310-5321 Disease denotes hemorrhages MESH:D006470
233 5325-5332 Disease denotes infarct MESH:D007238
234 5348-5358 Disease denotes hemorrhage MESH:D006470
235 5360-5367 Disease denotes infarct MESH:D007238
236 5373-5389 Disease denotes small hemorrhage MESH:D006470
237 5432-5442 Disease denotes hemorrhage MESH:D006470
238 5512-5535 Disease denotes parenchymal hemorrhages MESH:D002543
239 5581-5584 Disease denotes ICH MESH:D002543
241 5946-5953 Species denotes Patient Tax:9606
267 7190-7200 Disease denotes hemorrhage MESH:D006470
268 7231-7242 Disease denotes hemorrhages MESH:D006470
269 7409-7433 Disease denotes Congestive heart failure MESH:D006333
270 7458-7473 Disease denotes Coronary artery MESH:D003324
271 7510-7518 Disease denotes Diabetes MESH:D003920
272 7548-7562 Disease denotes Hyperlipidemia MESH:D006949
273 7593-7605 Disease denotes Hypertension MESH:D006973
274 7636-7650 Disease denotes Hypothyroidism MESH:D007037
275 7674-7687 Disease denotes Liver disease MESH:D008107
276 7717-7727 Disease denotes malignancy MESH:D009369
277 7760-7766 Disease denotes stroke MESH:D020521
278 7790-7803 Disease denotes Renal disease MESH:D007674
279 7834-7844 Disease denotes Hemorrhage MESH:D006470
280 7969-7972 Disease denotes ICH MESH:D002543
281 8047-8061 Disease denotes Encephalopathy MESH:D001927
282 8096-8104 Disease denotes weakness MESH:D018908
283 8221-8228 Disease denotes Seizure MESH:D012640
284 8296-8306 Disease denotes Hemorrhage MESH:D006470
285 8373-8376 Disease denotes ICH MESH:D002543
286 8427-8430 Disease denotes ICH MESH:D002543
287 8665-8668 Disease denotes ICH MESH:D002543
288 8752-8755 Disease denotes ICH MESH:D002543
289 8830-8833 Disease denotes ICH MESH:D002543
290 8917-8920 Disease denotes ICH MESH:D002543
291 8977-8986 Disease denotes Mortality MESH:D003643
295 6939-6947 Species denotes patients Tax:9606
296 6953-6976 Disease denotes intracranial hemorrhage MESH:D020300
297 7069-7079 Disease denotes hemorrhage MESH:D006470
300 9103-9106 Disease denotes ICH MESH:D002543
301 9109-9132 Disease denotes intracranial hemorrhage MESH:D020300
318 6032-6040 Species denotes patients Tax:9606
319 6238-6246 Species denotes patients Tax:9606
320 6259-6267 Species denotes patients Tax:9606
321 6307-6315 Species denotes patients Tax:9606
322 6446-6454 Species denotes patients Tax:9606
323 6559-6567 Species denotes patients Tax:9606
324 6706-6714 Species denotes patients Tax:9606
325 6014-6022 Disease denotes COVID-19 MESH:C000657245
326 6046-6049 Disease denotes ICH MESH:D002543
327 6125-6128 Disease denotes ICH MESH:D002543
328 6205-6214 Disease denotes mortality MESH:D003643
329 6370-6380 Disease denotes hemorrhage MESH:D006470
330 6474-6477 Disease denotes ICH MESH:D002543
331 6673-6683 Disease denotes hemorrhage MESH:D006470
332 6720-6736 Disease denotes thrombocytopenic MESH:D013921
333 6811-6821 Disease denotes hemorrhage MESH:D006470
337 10555-10562 Chemical denotes heparin MESH:D006493
338 10304-10314 Disease denotes hemorrhage MESH:D006470
339 10345-10356 Disease denotes hemorrhages MESH:D006470
342 10179-10187 Species denotes patients Tax:9606
343 10193-10216 Disease denotes intracranial hemorrhage MESH:D020300
346 11213-11221 Species denotes patients Tax:9606
347 11263-11271 Species denotes patients Tax:9606
360 9382-9390 Species denotes patients Tax:9606
361 9466-9474 Species denotes patients Tax:9606
362 9487-9495 Species denotes patients Tax:9606
363 9612-9620 Species denotes patients Tax:9606
364 9921-9929 Species denotes patients Tax:9606
365 10029-10036 Species denotes patient Tax:9606
366 9548-9556 Chemical denotes warfarin MESH:D014859
367 9561-9571 Chemical denotes dabigatran MESH:D000069604
368 9337-9340 Disease denotes ICH MESH:D002543
369 9515-9525 Disease denotes hemorrhage MESH:D006470
370 9751-9767 Disease denotes thrombocytopenia MESH:D013921
371 9839-9849 Disease denotes hemorrhage MESH:D006470
393 11420-11428 Species denotes patients Tax:9606
394 11516-11524 Species denotes patients Tax:9606
395 11667-11675 Species denotes patients Tax:9606
396 12131-12139 Species denotes patients Tax:9606
397 12228-12236 Species denotes patients Tax:9606
398 11785-11792 Chemical denotes heparin MESH:D006493
399 11794-11797 Chemical denotes UFH MESH:D006493
400 11819-11822 Chemical denotes UFH MESH:D006493
401 11827-11837 Chemical denotes enoxaparin MESH:D017984
402 11877-11880 Chemical denotes UFH MESH:D006493
403 11885-11895 Chemical denotes argatroban MESH:C031942
404 11943-11953 Chemical denotes enoxaparin MESH:D017984
405 11971-11974 Chemical denotes UFH MESH:D006493
406 11979-11989 Chemical denotes enoxaparin MESH:D017984
407 12030-12040 Chemical denotes Argatroban MESH:C031942
408 12077-12084 Chemical denotes heparin MESH:D006493
409 11634-11642 Disease denotes thrombus MESH:D013927
410 12093-12109 Disease denotes thrombocytopenia MESH:D013921
411 12111-12114 Disease denotes HIT MESH:D013921
412 12156-12159 Disease denotes HIT MESH:D013921
413 12380-12383 Disease denotes ICH MESH:D002543
415 12395-12417 Disease denotes parenchymal hemorrhage MESH:D002543
431 12453-12461 Species denotes patients Tax:9606
432 12591-12599 Species denotes patients Tax:9606
433 12728-12736 Species denotes patients Tax:9606
434 12943-12951 Species denotes patients Tax:9606
435 12961-12969 Species denotes patients Tax:9606
436 12467-12470 Disease denotes ICH MESH:D002543
437 12498-12509 Disease denotes hemorrhages MESH:D006470
438 12642-12684 Disease denotes hypoxic ischemic injury and brain swelling MESH:D001929
439 12696-12705 Disease denotes mortality MESH:D003643
440 12830-12838 Disease denotes thrombus MESH:D013927
441 12860-12870 Disease denotes hemorrhage MESH:D006470
442 13137-13148 Disease denotes hemorrhages MESH:D006470
443 13176-13179 Disease denotes ICH MESH:D002543
444 13192-13203 Disease denotes hemorrhagic MESH:D006470
445 13218-13233 Disease denotes ischemic stroke MESH:D002544
458 13251-13259 Species denotes patients Tax:9606
459 13643-13651 Species denotes patients Tax:9606
460 13709-13717 Species denotes patients Tax:9606
461 13265-13268 Disease denotes ICH MESH:D002543
462 13291-13302 Disease denotes hemorrhages MESH:D006470
463 13354-13365 Disease denotes hemorrhages MESH:D006470
464 13408-13418 Disease denotes hemorrhage MESH:D006470
465 13562-13573 Disease denotes hemorrhagic MESH:D006470
466 13591-13607 Disease denotes ischemic infarct MESH:D009203
467 13609-13618 Disease denotes Mortality MESH:D003643
468 13676-13687 Disease denotes hemorrhages MESH:D006470
469 13736-13747 Disease denotes hemorrhages MESH:D006470
487 13831-13839 Species denotes patients Tax:9606
488 14132-14140 Species denotes patients Tax:9606
489 14238-14246 Species denotes patients Tax:9606
490 14483-14491 Species denotes patients Tax:9606
491 14299-14302 Chemical denotes UFH MESH:D006493
492 13822-13830 Disease denotes COVID-19 MESH:C000657245
493 13878-13896 Disease denotes hypercoagulability MESH:D019851
494 14005-14008 Disease denotes ICH MESH:D002543
495 14165-14173 Disease denotes COVID-19 MESH:C000657245
496 14211-14214 Disease denotes ICH MESH:D002543
497 14465-14473 Disease denotes COVID-19 MESH:C000657245
498 14513-14531 Disease denotes hypercoagulability MESH:D019851
499 14581-14592 Disease denotes hemorrhages MESH:D006470
500 14653-14676 Disease denotes intracranial hemorrhage MESH:D020300
501 14704-14715 Disease denotes hemorrhages MESH:D006470
502 14721-14732 Disease denotes hemorrhagic MESH:D006470
503 14751-14766 Disease denotes ischemic stroke MESH:D002544
519 14812-14820 Species denotes patients Tax:9606
520 14920-14928 Species denotes patients Tax:9606
521 15060-15068 Species denotes patients Tax:9606
522 15334-15342 Species denotes patients Tax:9606
523 15651-15659 Species denotes patients Tax:9606
524 14961-14964 Chemical denotes UFH MESH:D006493
525 14844-14855 Disease denotes hemorrhages MESH:D006470
526 14892-14901 Disease denotes Mortality MESH:D003643
527 14988-14999 Disease denotes hemorrhages MESH:D006470
528 15138-15148 Disease denotes thrombosis MESH:D013927
529 15312-15321 Disease denotes mortality MESH:D003643
530 15325-15333 Disease denotes COVID-19 MESH:C000657245
531 15530-15538 Disease denotes COVID-19 MESH:C000657245
532 15761-15784 Disease denotes catastrophic hemorrhage MESH:D006470
533 15815-15822 Disease denotes infarct MESH:D007238
542 15843-15851 Species denotes patients Tax:9606
543 16204-16212 Species denotes patients Tax:9606
544 15865-15876 Disease denotes hemorrhages MESH:D006470
545 15972-15995 Disease denotes subarachnoid hemorrhage MESH:D013345
546 16083-16086 Disease denotes ICH MESH:D002543
547 16180-16188 Disease denotes COVID-19 MESH:C000657245
548 16218-16221 Disease denotes ICH MESH:D002543
549 16234-16237 Disease denotes ICH MESH:D002543
563 16420-16428 Species denotes patients Tax:9606
564 16492-16500 Species denotes patients Tax:9606
565 16911-16919 Species denotes patients Tax:9606
566 17006-17014 Species denotes patients Tax:9606
567 17027-17035 Species denotes patients Tax:9606
568 16822-16830 Species denotes patients Tax:9606
569 16434-16437 Disease denotes ICH MESH:D002543
570 16731-16734 Disease denotes ICH MESH:D002543
571 16813-16821 Disease denotes COVID-19 MESH:C000657245
572 16883-16886 Disease denotes ICH MESH:D002543
573 16945-16955 Disease denotes hemorrhage MESH:D006470
574 17018-17026 Disease denotes COVID-19 MESH:C000657245
575 17077-17087 Disease denotes hemorrhage MESH:D006470
581 17193-17201 Species denotes patients Tax:9606
582 17331-17339 Species denotes patients Tax:9606
583 17166-17169 Disease denotes ICH MESH:D002543
584 17220-17228 Disease denotes COVID-19 MESH:C000657245
585 17322-17330 Disease denotes COVID-19 MESH:C000657245
587 17489-17495 Disease denotes Cancer MESH:D009369

2_test

Id Subject Object Predicate Lexical cue
32689588-32171076-64892979 1890-1891 32171076 denotes 3
32689588-32171076-64892980 2158-2159 32171076 denotes 3
32689588-26660118-64892981 2836-2837 26660118 denotes 5
32689588-23287421-64892982 2840-2841 23287421 denotes 6
32689588-32278361-64892983 3038-3039 32278361 denotes 7
32689588-32447193-64892984 3206-3207 32447193 denotes 9
32689588-23687625-64892985 4983-4985 23687625 denotes 10
32689588-11157179-64892986 5578-5580 11157179 denotes 12
32689588-11283388-64892987 5623-5625 11283388 denotes 13
32689588-32220112-64892988 15374-15376 32220112 denotes 14
32689588-28030895-64892989 16087-16089 28030895 denotes 15