PMC:7243778 / 8895-9780
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
198 | 600-604 | Gene | denotes | ACE2 | Gene:59272 |
199 | 13-21 | Species | denotes | SARS-CoV | Tax:694009 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T41 | 2-9 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T42 | 515-526 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T23 | 13-21 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T97 | 86-88 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T98 | 99-101 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T99 | 151-153 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T100 | 151-153 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T101 | 164-166 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T102 | 189-197 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T103 | 234-242 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T104 | 244-246 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T105 | 247-262 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | is organized in |
T106 | 247-262 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | is organized in |
T107 | 285-286 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T108 | 325-326 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T109 | 357-359 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T110 | 430-432 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T111 | 614-616 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T112 | 659-667 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T113 | 687-688 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T114 | 716-718 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T115 | 716-718 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T116 | 739-747 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T117 | 800-802 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T118 | 821-823 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T35 | 2-9 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T36 | 151-153 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T37 | 515-526 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
T38 | 515-520 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T39 | 521-526 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T40 | 716-718 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T41 | 739-747 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T17 | 189-204 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
T18 | 484-497 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T70 | 0-243 | Sentence | denotes | S protein of SARS-CoV is composed of two functionally distinct subunits: the globular S1 subunit (~aa 12–680) allows receptor recognition, whereas the S2 subunit (~aa 681–1255) facilitates membrane fusion and anchors S into the viral membrane. |
T71 | 244-289 | Sentence | denotes | S1 is organized in four distinct domains A–D. |
T72 | 290-447 | Sentence | denotes | Domains S1A and S1B may be used as a receptor-binding domain (RBD, aa 318–510) containing the highly conserved receptor-binding motif (RBM, aa 424–494) [21]. |
T73 | 448-618 | Sentence | denotes | Moreover, RBD contains 3 functional glycosylation sites located at amino acids 318, 330 and 357, which are necessary for S expression but do not affect ACE2 binding [22]. |
T74 | 619-715 | Sentence | denotes | S1B forms an extended loop on the viral membrane-distal side and is a hypervariable region [20]. |
T75 | 716-885 | Sentence | denotes | S2 contains the fusion peptides (FP1 and FP2) [23], two heptad repeat regions (HR1, aa ~889–972 and HR2, aa ~1142–1193) and the well conserved transmembrane domain [24]. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32450171-16122388-66454450 | 614-616 | 16122388 | denotes | 22 |
32450171-27030273-66454451 | 763-765 | 27030273 | denotes | 23 |
32450171-15161975-66454452 | 881-883 | 15161975 | denotes | 24 |