PMC:7243778 / 34513-35090 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"898","span":{"begin":71,"end":81},"obj":"Species"},{"id":"899","span":{"begin":163,"end":173},"obj":"Species"},{"id":"900","span":{"begin":558,"end":566},"obj":"Species"},{"id":"901","span":{"begin":389,"end":397},"obj":"Disease"},{"id":"902","span":{"begin":429,"end":439},"obj":"Mutation"},{"id":"903","span":{"begin":441,"end":448},"obj":"Mutation"}],"attributes":[{"id":"A898","pred":"tao:has_database_id","subj":"898","obj":"Tax:2697049"},{"id":"A899","pred":"tao:has_database_id","subj":"899","obj":"Tax:2697049"},{"id":"A900","pred":"tao:has_database_id","subj":"900","obj":"Tax:9606"},{"id":"A901","pred":"tao:has_database_id","subj":"901","obj":"MESH:C000657245"},{"id":"A902","pred":"tao:has_standard_notation","subj":"902","obj":"g.23403A\u003eG"},{"id":"A903","pred":"tao:has_standard_notation","subj":"903","obj":"p.D614G"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T171","span":{"begin":42,"end":45},"obj":"Body_part"},{"id":"T172","span":{"begin":267,"end":272},"obj":"Body_part"}],"attributes":[{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T180","span":{"begin":71,"end":79},"obj":"Disease"},{"id":"T181","span":{"begin":163,"end":171},"obj":"Disease"},{"id":"T182","span":{"begin":389,"end":397},"obj":"Disease"}],"attributes":[{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A182","pred":"mondo_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T405","span":{"begin":46,"end":51},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T406","span":{"begin":178,"end":179},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T407","span":{"begin":265,"end":272},"obj":"http://purl.obolibrary.org/obo/CL_0000236"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T194","span":{"begin":549,"end":554},"obj":"Chemical"}],"attributes":[{"id":"A194","pred":"chebi_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T29","span":{"begin":116,"end":133},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T30","span":{"begin":116,"end":133},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T267","span":{"begin":0,"end":140},"obj":"Sentence"},{"id":"T268","span":{"begin":141,"end":273},"obj":"Sentence"},{"id":"T269","span":{"begin":274,"end":348},"obj":"Sentence"},{"id":"T270","span":{"begin":349,"end":407},"obj":"Sentence"},{"id":"T271","span":{"begin":408,"end":577},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Due to the lack of repairing mechanism of RNA virus replicase complex, SARS-CoV-2 mutations frequently occur during viral replication [111]. The genetic drifts of SARS-CoV-2 are a selective evolution toward less immunogenicity for host immune surveillance by T- or B-cells. The latter appearing strains are less immunogenic than earlier ones [113]. Antigenic drift is also reported in the COVID-19 pandemic. The highly prevalent 23403A \u003e G (p.D614G) variant in the European population may result in vaccine mismatches with little protection to that group of patients [114,115]."}