PMC:7243778 / 32452-32926 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"845","span":{"begin":156,"end":160},"obj":"Gene"},{"id":"846","span":{"begin":125,"end":135},"obj":"Species"},{"id":"847","span":{"begin":254,"end":264},"obj":"Species"},{"id":"848","span":{"begin":296,"end":306},"obj":"Species"},{"id":"849","span":{"begin":322,"end":330},"obj":"Species"},{"id":"850","span":{"begin":410,"end":418},"obj":"Species"},{"id":"851","span":{"begin":423,"end":433},"obj":"Species"},{"id":"852","span":{"begin":457,"end":467},"obj":"Species"},{"id":"853","span":{"begin":80,"end":83},"obj":"Chemical"},{"id":"854","span":{"begin":99,"end":103},"obj":"Chemical"},{"id":"855","span":{"begin":202,"end":206},"obj":"Chemical"},{"id":"856","span":{"begin":207,"end":213},"obj":"Chemical"},{"id":"857","span":{"begin":281,"end":292},"obj":"Chemical"},{"id":"858","span":{"begin":367,"end":371},"obj":"Chemical"},{"id":"859","span":{"begin":49,"end":66},"obj":"Disease"}],"attributes":[{"id":"A845","pred":"tao:has_database_id","subj":"845","obj":"Gene:59272"},{"id":"A846","pred":"tao:has_database_id","subj":"846","obj":"Tax:2697049"},{"id":"A847","pred":"tao:has_database_id","subj":"847","obj":"Tax:2697049"},{"id":"A848","pred":"tao:has_database_id","subj":"848","obj":"Tax:2697049"},{"id":"A849","pred":"tao:has_database_id","subj":"849","obj":"Tax:694009"},{"id":"A850","pred":"tao:has_database_id","subj":"850","obj":"Tax:694009"},{"id":"A851","pred":"tao:has_database_id","subj":"851","obj":"Tax:2697049"},{"id":"A852","pred":"tao:has_database_id","subj":"852","obj":"Tax:2697049"},{"id":"A856","pred":"tao:has_database_id","subj":"856","obj":"MESH:D011134"},{"id":"A859","pred":"tao:has_database_id","subj":"859","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T160","span":{"begin":19,"end":24},"obj":"Body_part"}],"attributes":[{"id":"A160","pred":"fma_id","subj":"T160","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T165","span":{"begin":49,"end":57},"obj":"Disease"},{"id":"T166","span":{"begin":125,"end":133},"obj":"Disease"},{"id":"T167","span":{"begin":254,"end":262},"obj":"Disease"},{"id":"T168","span":{"begin":296,"end":304},"obj":"Disease"},{"id":"T169","span":{"begin":322,"end":330},"obj":"Disease"},{"id":"T170","span":{"begin":410,"end":418},"obj":"Disease"},{"id":"T171","span":{"begin":423,"end":431},"obj":"Disease"},{"id":"T172","span":{"begin":457,"end":465},"obj":"Disease"}],"attributes":[{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A170","pred":"mondo_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A172","pred":"mondo_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T383","span":{"begin":17,"end":24},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T384","span":{"begin":30,"end":31},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T385","span":{"begin":200,"end":201},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T182","span":{"begin":214,"end":221},"obj":"Chemical"}],"attributes":[{"id":"A182","pred":"chebi_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/CHEBI_53000"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T27","span":{"begin":10,"end":16},"obj":"http://purl.obolibrary.org/obo/GO_0007613"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T250","span":{"begin":0,"end":169},"obj":"Sentence"},{"id":"T251","span":{"begin":170,"end":265},"obj":"Sentence"},{"id":"T252","span":{"begin":266,"end":366},"obj":"Sentence"},{"id":"T253","span":{"begin":367,"end":474},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Using the memory B cells from a survivor who was SARS-CoV infected in 2003, one nAb anti-RBD named S309 was found to bind to SARS-CoV-2 without interfering ACE2 binding. Besides, S309 could recognize a N343-glycan epitope that is distant from the RBM of SARS-CoV-2. Interestingly, N343-glycan of SARS-CoV-2 corresponds to SARS-CoV N330 and they are highly conserved. S309 potently neutralized both pseudotyped SARS-CoV and SARS-CoV-2 and also the authentic SARS-CoV-2 [109]."}