PMC:7243778 / 30847-31582 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"792","span":{"begin":67,"end":70},"obj":"Gene"},{"id":"793","span":{"begin":59,"end":62},"obj":"Gene"},{"id":"794","span":{"begin":87,"end":88},"obj":"Gene"},{"id":"795","span":{"begin":76,"end":86},"obj":"Species"},{"id":"796","span":{"begin":132,"end":140},"obj":"Species"},{"id":"797","span":{"begin":152,"end":160},"obj":"Species"},{"id":"798","span":{"begin":161,"end":169},"obj":"Species"},{"id":"799","span":{"begin":354,"end":364},"obj":"Species"},{"id":"800","span":{"begin":442,"end":453},"obj":"Species"},{"id":"801","span":{"begin":507,"end":515},"obj":"Species"},{"id":"802","span":{"begin":520,"end":530},"obj":"Species"},{"id":"803","span":{"begin":531,"end":539},"obj":"Species"},{"id":"804","span":{"begin":597,"end":608},"obj":"Species"},{"id":"805","span":{"begin":637,"end":645},"obj":"Species"},{"id":"806","span":{"begin":646,"end":654},"obj":"Species"},{"id":"807","span":{"begin":672,"end":680},"obj":"Species"},{"id":"808","span":{"begin":694,"end":704},"obj":"Species"},{"id":"809","span":{"begin":123,"end":131},"obj":"Disease"}],"attributes":[{"id":"A792","pred":"tao:has_database_id","subj":"792","obj":"Gene:6227"},{"id":"A793","pred":"tao:has_database_id","subj":"793","obj":"Gene:6208"},{"id":"A794","pred":"tao:has_database_id","subj":"794","obj":"Gene:43740568"},{"id":"A795","pred":"tao:has_database_id","subj":"795","obj":"Tax:2697049"},{"id":"A796","pred":"tao:has_database_id","subj":"796","obj":"Tax:9606"},{"id":"A797","pred":"tao:has_database_id","subj":"797","obj":"Tax:694009"},{"id":"A798","pred":"tao:has_database_id","subj":"798","obj":"Tax:9606"},{"id":"A799","pred":"tao:has_database_id","subj":"799","obj":"Tax:2697049"},{"id":"A800","pred":"tao:has_database_id","subj":"800","obj":"Tax:11118"},{"id":"A801","pred":"tao:has_database_id","subj":"801","obj":"Tax:694009"},{"id":"A802","pred":"tao:has_database_id","subj":"802","obj":"Tax:2697049"},{"id":"A803","pred":"tao:has_database_id","subj":"803","obj":"Tax:9606"},{"id":"A804","pred":"tao:has_database_id","subj":"804","obj":"Tax:11118"},{"id":"A805","pred":"tao:has_database_id","subj":"805","obj":"Tax:694009"},{"id":"A806","pred":"tao:has_database_id","subj":"806","obj":"Tax:9606"},{"id":"A807","pred":"tao:has_database_id","subj":"807","obj":"Tax:694009"},{"id":"A808","pred":"tao:has_database_id","subj":"808","obj":"Tax:2697049"},{"id":"A809","pred":"tao:has_database_id","subj":"809","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T150","span":{"begin":76,"end":84},"obj":"Disease"},{"id":"T151","span":{"begin":123,"end":131},"obj":"Disease"},{"id":"T152","span":{"begin":152,"end":160},"obj":"Disease"},{"id":"T153","span":{"begin":354,"end":362},"obj":"Disease"},{"id":"T154","span":{"begin":507,"end":515},"obj":"Disease"},{"id":"T155","span":{"begin":520,"end":528},"obj":"Disease"},{"id":"T156","span":{"begin":637,"end":645},"obj":"Disease"},{"id":"T157","span":{"begin":672,"end":680},"obj":"Disease"},{"id":"T158","span":{"begin":694,"end":702},"obj":"Disease"}],"attributes":[{"id":"A150","pred":"mondo_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A151","pred":"mondo_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A152","pred":"mondo_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A153","pred":"mondo_id","subj":"T153","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A154","pred":"mondo_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A155","pred":"mondo_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A156","pred":"mondo_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T365","span":{"begin":0,"end":8},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T366","span":{"begin":45,"end":52},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T367","span":{"begin":207,"end":215},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T368","span":{"begin":431,"end":438},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T369","span":{"begin":581,"end":582},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T370","span":{"begin":593,"end":596},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9596"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T171","span":{"begin":45,"end":52},"obj":"Chemical"},{"id":"T172","span":{"begin":207,"end":215},"obj":"Chemical"},{"id":"T173","span":{"begin":431,"end":438},"obj":"Chemical"},{"id":"T174","span":{"begin":609,"end":616},"obj":"Chemical"}],"attributes":[{"id":"A171","pred":"chebi_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A172","pred":"chebi_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A173","pred":"chebi_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A174","pred":"chebi_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/CHEBI_53000"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T240","span":{"begin":0,"end":243},"obj":"Sentence"},{"id":"T241","span":{"begin":244,"end":380},"obj":"Sentence"},{"id":"T242","span":{"begin":381,"end":540},"obj":"Sentence"},{"id":"T243","span":{"begin":541,"end":617},"obj":"Sentence"},{"id":"T244","span":{"begin":618,"end":735},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}

{"project":"2_test","denotations":[{"id":"32450171-19439480-66454514","span":{"begin":455,"end":458},"obj":"19439480"}],"text":"Peptides S14P5 and S21P2 in the two distinct peptide pools S14 and S21 from SARS-CoV-2 S library were strongly detected in COVID-19 patients but not in SARS-CoV patients by using pools of overlapping linear peptides and functional assays [78]. With the data from antibodies depletion assays, researchers indicated that S14P5 and S21P2 were necessary for SARS-CoV-2 neutralization. Moreover, pool S51 contains very conserved fusion peptide in coronavirus [106,107] and is partially overlapped in the sera of SARS-CoV and SARS-CoV-2 patients. These results suggested that S51 may be a potential pan-coronavirus epitope. Sera from recalled SARS-CoV patients could neutralize SARS-CoV, but not the SARS-CoV-2 pseudotyped lentiviruses [78]."}