PMC:7243778 / 28602-29684
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
714 | 232-236 | Gene | denotes | ACE2 | Gene:59272 |
715 | 790-791 | Gene | denotes | S | Gene:43740568 |
716 | 29-39 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
717 | 76-84 | Species | denotes | SARS-CoV | Tax:694009 |
718 | 88-98 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
719 | 442-450 | Species | denotes | SARS-CoV | Tax:694009 |
720 | 511-521 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
721 | 603-611 | Species | denotes | SARS-CoV | Tax:694009 |
722 | 658-668 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
723 | 725-735 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
724 | 803-813 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
725 | 943-951 | Species | denotes | SARS-CoV | Tax:694009 |
726 | 1058-1066 | Species | denotes | SARS-CoV | Tax:694009 |
727 | 1071-1081 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
728 | 142-147 | Species | denotes | human | Tax:9606 |
729 | 821-830 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T131 | 154-162 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T132 | 263-275 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T133 | 263-267 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T134 | 647-654 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T135 | 792-799 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T136 | 881-903 | Body_part | denotes | cytotoxic T-lymphocyte | http://purl.org/sig/ont/fma/fma70573 |
T137 | 891-903 | Body_part | denotes | T-lymphocyte | http://purl.org/sig/ont/fma/fma62870 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T127 | 29-37 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T128 | 76-84 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T129 | 88-96 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T130 | 442-450 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T131 | 511-519 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T132 | 603-611 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T133 | 658-666 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T134 | 725-733 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T135 | 803-811 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T136 | 821-830 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T137 | 943-951 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T138 | 1058-1066 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T139 | 1071-1079 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T334 | 0-2 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T335 | 6-7 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T336 | 62-64 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T337 | 99-102 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T338 | 142-147 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T339 | 185-192 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T340 | 263-267 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T341 | 307-315 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T342 | 428-430 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T343 | 428-430 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T344 | 454-456 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T345 | 556-560 | http://purl.obolibrary.org/obo/CLO_0001165 | denotes | 1G10 |
T346 | 589-591 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T347 | 589-591 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T348 | 711-713 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T349 | 711-713 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T350 | 744-745 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T351 | 761-763 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T352 | 914-916 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
T353 | 952-954 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T354 | 952-954 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T161 | 17-24 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
T162 | 428-430 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T163 | 589-591 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T164 | 647-654 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T165 | 711-713 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T166 | 752-759 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
T167 | 792-799 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T168 | 843-850 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
T169 | 952-954 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22 | 1024-1049 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
T23 | 1024-1049 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
T24 | 1024-1049 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T4 | 556-560 | GlycoEpitope | denotes | 1G10 | http://www.glycoepitope.jp/epitopes/AN0438 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T224 | 0-57 | Sentence | denotes | S1 is a specific antigen for SARS-CoV-2 diagnostics [98]. |
T225 | 58-137 | Sentence | denotes | The S1 subunit of SARS-CoV or SARS-CoV-2 has four core domains S1A through S1D. |
T226 | 138-398 | Sentence | denotes | The human 47D11 antibody binds the S1B of both viruses, without competing with S1B binding to ACE2 receptor expressed at the cell surface, and showed cross-neutralizing activity by an unknown mechanism that is different from receptor binding interference [99]. |
T227 | 399-522 | Sentence | denotes | An immunogenic domain in the S2 subunit of SARS-CoV S (aa 1029–1192) was highly conserved in several strains of SARS-CoV-2. |
T228 | 523-669 | Sentence | denotes | Four murine monoclonal Abs, 1A9, 1G10, 2B2 and 4B12, against this S2 subunit of SARS-CoV can also cross-reactive with the S protein of SARS-CoV-2. |
T229 | 670-837 | Sentence | denotes | Interestingly, 1A9 can strongly bind the S2 subunit of SARS-CoV-2 through a novel epitope (aa 1111–1130) and can detect S protein in SARS-CoV-2 during infection [100]. |
T230 | 838-969 | Sentence | denotes | This epitope also overlaps with one of two cytotoxic T-lymphocyte epitopes (aa 884–891 and 1116–1123) of SARS-CoV S2 subunit [101]. |
T231 | 970-1082 | Sentence | denotes | 1A9 is therefore suggested to induce both humoral and cellular immune responses against SARS-CoV and SARS-CoV-2. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32450171-19475608-66454513 | 964-967 | 19475608 | denotes | 101 |