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PMC:7243778 / 27661-28601 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
684 370-374 Gene denotes CDR3 Gene:8163
685 444-448 Gene denotes ACE2 Gene:59272
686 165-173 Species denotes SARS-CoV Tax:694009
687 177-185 Species denotes MERS-CoV Tax:1335626
688 245-255 Species denotes SARS-CoV-2 Tax:2697049
689 281-289 Species denotes patients Tax:9606
690 710-718 Species denotes SARS-CoV Tax:694009
691 832-842 Species denotes SARS-Cov-2 Tax:2697049
692 924-934 Species denotes SARS-CoV-2 Tax:2697049
693 83-93 Species denotes SARS-CoV-2 Tax:2697049
694 843-846 Gene denotes ACE Gene:1636
695 700-706 Chemical denotes CR3022
696 896-902 Chemical denotes CR3022
697 113-121 Disease denotes infected MESH:D007239

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T125 0-8 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T126 122-128 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T127 320-328 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T128 353-361 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T129 576-584 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T130 732-740 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T121 83-91 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 165-173 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T123 245-253 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 710-718 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T125 832-836 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T126 924-932 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T328 122-128 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T329 190-191 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T330 565-566 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T331 708-709 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 765-769 http://purl.obolibrary.org/obo/CLO_0001692 denotes a kd
T333 863-865 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T159 677-686 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T160 786-793 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T216 0-51 Sentence denotes Antibody response to RBD is viral species-specific.
T217 52-186 Sentence denotes Effectively, none of the found SARS-CoV-2 antibodies nor the infected plasma cross-reacted with RBDs from either SARS-CoV or MERS-CoV.
T218 187-290 Sentence denotes In a study, 206 monoclonal antibodies specific to the RBD SARS-CoV-2 were identified in eight patients.
T219 291-443 Sentence denotes These mAbs are different in: antibody heavy and light chains, antibody clones, CDR3 length… which lead to different binding and neutralizing capacities.
T220 444-535 Sentence denotes ACE2 is out-competed with almost 100% efficacity by some mAbs such as P2B-2F6 and P2C-1F11.
T221 536-699 Sentence denotes Interestingly the latter and a moderate antibody P2C-1C10 seems to target the different epitopes, and they could be combined for synergistic antiviral effect [96].
T222 700-867 Sentence denotes CR3022, a SARS-CoV RBD-specific antibody, can bind strongly with a kd of 6.3 nM to an epitope on RBD that does not overlap with the SARS-Cov-2 ACE-2 binding site [34].
T223 868-940 Sentence denotes Despite its strong binding, CR3022 could not neutralize SARS-CoV-2 [97].

2_test

Id Subject Object Predicate Lexical cue
32450171-32065055-66454512 863-865 32065055 denotes 34