PMC:7243778 / 23153-23960
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 573 | 97-101 | Gene | denotes | ACE2 | Gene:59272 |
| 574 | 453-457 | Gene | denotes | ACE2 | Gene:59272 |
| 575 | 67-68 | Gene | denotes | N | Gene:43740575 |
| 576 | 0-1 | Gene | denotes | S | Gene:43740568 |
| 577 | 13-23 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 578 | 139-147 | Species | denotes | SARS-CoV | Tax:694009 |
| 579 | 373-383 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 580 | 362-371 | Disease | denotes | infection | MESH:D007239 |
| 581 | 786-801 | Disease | denotes | virus infection | MESH:D001102 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T96 | 2-9 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T97 | 41-52 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T98 | 150-162 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T99 | 405-409 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T100 | 576-580 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T101 | 668-678 | Body_part | denotes | Antibodies | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T85 | 13-21 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T86 | 139-147 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T87 | 238-241 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T89 | 362-371 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T90 | 373-381 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T91 | 786-801 | Disease | denotes | virus infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T92 | 792-801 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T288 | 78-80 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T289 | 116-117 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T290 | 192-194 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T291 | 247-248 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T292 | 326-327 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T293 | 405-409 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T294 | 442-444 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T295 | 500-502 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T296 | 500-502 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T297 | 537-542 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T298 | 576-580 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T299 | 637-638 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T300 | 735-742 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T301 | 786-791 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T302 | 803-805 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T134 | 2-9 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T135 | 41-52 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T136 | 41-46 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T137 | 47-52 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T138 | 150-162 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T139 | 500-502 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T140 | 654-661 | Chemical | denotes | epitope | http://purl.obolibrary.org/obo/CHEBI_53000 |
| T141 | 735-742 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T179 | 0-178 | Sentence | denotes | S protein of SARS-CoV-2 composed of 1273 amino acids [76] uses its N-terminal S1 subunit to bind ACE2 receptor with a better affinity than SARS-CoV S glycoprotein for entry [78]. |
| T180 | 179-279 | Sentence | denotes | Effectively, S1 subunit divides into an N-terminal domain (NTD) and a receptor-binding domain (RBD). |
| T181 | 280-354 | Sentence | denotes | The latter is necessary for viral binding and a potential target for nAbs. |
| T182 | 355-589 | Sentence | denotes | During infection, SARS-CoV-2 first binds the host cell through interaction between its S1-RBD and ACE2, triggering conformational changes in the S2 subunit that is indispensable for virus fusion and entry into the target cell [79,80]. |
| T183 | 590-667 | Sentence | denotes | Some recent studies also confirmed that RBD is a conformational epitope [78]. |
| T184 | 668-807 | Sentence | denotes | Antibodies binding RBD may sterically hinder binding to the nearby peptide S14P5 of ACE2 receptor, thereby abolishing virus infection [34]. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32450171-19198616-66454502 | 582-584 | 19198616 | denotes | 79 |
| 32450171-27936982-66454503 | 585-587 | 27936982 | denotes | 80 |
| 32450171-32065055-66454504 | 803-805 | 32065055 | denotes | 34 |