PMC:7243768 / 36274-37494
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1410 | 5-15 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1411 | 18-35 | Disease | denotes | diabetes mellitus | MESH:D003920 |
1425 | 91-95 | Gene | denotes | ACE2 | Gene:59272 |
1426 | 134-137 | Gene | denotes | ACE | Gene:1636 |
1427 | 174-178 | Gene | denotes | ACE2 | Gene:59272 |
1428 | 258-262 | Gene | denotes | ACE2 | Gene:59272 |
1429 | 400-404 | Gene | denotes | ACE2 | Gene:59272 |
1430 | 36-44 | Species | denotes | Patients | Tax:9606 |
1431 | 281-291 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1432 | 50-67 | Disease | denotes | diabetes mellitus | MESH:D003920 |
1433 | 180-188 | Disease | denotes | Diabetes | MESH:D003920 |
1434 | 325-333 | Disease | denotes | COVID-19 | MESH:C000657245 |
1435 | 341-358 | Disease | denotes | diabetes mellitus | MESH:D003920 |
1436 | 363-375 | Disease | denotes | hypertension | MESH:D006973 |
1437 | 450-458 | Disease | denotes | COVID-19 | MESH:C000657245 |
1451 | 508-512 | Gene | denotes | ACE2 | Gene:59272 |
1452 | 567-571 | Gene | denotes | ACE2 | Gene:59272 |
1453 | 538-548 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1454 | 704-712 | Species | denotes | patients | Tax:9606 |
1455 | 893-900 | Species | denotes | patient | Tax:9606 |
1456 | 1048-1055 | Species | denotes | patient | Tax:9606 |
1457 | 1161-1166 | Species | denotes | human | Tax:9606 |
1458 | 686-694 | Disease | denotes | COVID-19 | MESH:C000657245 |
1459 | 738-755 | Disease | denotes | diabetes mellitus | MESH:D003920 |
1460 | 916-928 | Disease | denotes | hypertension | MESH:D006973 |
1461 | 940-948 | Disease | denotes | COVID-19 | MESH:C000657245 |
1462 | 1039-1047 | Disease | denotes | diabetic | MESH:D003920 |
1463 | 1089-1097 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T313 | 306-311 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T314 | 598-605 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T417 | 5-13 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T418 | 5-9 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T419 | 18-35 | Disease | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005015 |
T420 | 50-67 | Disease | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005015 |
T421 | 180-188 | Disease | denotes | Diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
T422 | 281-289 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T423 | 281-285 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T424 | 325-333 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T425 | 341-358 | Disease | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005015 |
T426 | 363-375 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T427 | 450-458 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T428 | 538-546 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T429 | 538-542 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T430 | 686-694 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T431 | 738-755 | Disease | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005015 |
T432 | 916-928 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T433 | 940-948 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T434 | 1071-1073 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
T435 | 1089-1097 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T498 | 306-311 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T499 | 433-434 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T500 | 970-973 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T501 | 1037-1038 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T502 | 1161-1166 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T194 | 120-130 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T195 | 416-421 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
T196 | 598-605 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T197 | 800-804 | Chemical | denotes | ACEi | http://purl.obolibrary.org/obo/CHEBI_35457 |
T198 | 1201-1205 | Chemical | denotes | ACEi | http://purl.obolibrary.org/obo/CHEBI_35457 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T244 | 0-35 | Sentence | denotes | 6.4 SARS-CoV-2 – diabetes mellitus |
T245 | 36-179 | Sentence | denotes | Patients with diabetes mellitus exhibit high levels of ACE2, and treatment with the inhibitors of ACE and ARBs augments the expression of ACE2. |
T246 | 180-334 | Sentence | denotes | Diabetes condition may lead to the suspicion that the excessive expression of ACE2 aids the entry of SARS-CoV-2 into the host cells resulting in COVID-19. |
T247 | 335-464 | Sentence | denotes | Since diabetes mellitus and hypertension conditions are treated, ACE2 increasing drugs are having a severe risk of COVID-19 [10]. |
T248 | 465-640 | Sentence | denotes | Simultaneously, the elevated expression of ACE2 ensures the entry of the SARS-CoV-2, attaching to the ACE2 enzyme with the help of S protein present on its envelope's surface. |
T249 | 641-821 | Sentence | denotes | There forth, it became controversial whether COVID-19 affected patients who are predisposed with diabetes mellitus should be resumed with their treatment with ACEi and ARBs or not. |
T250 | 822-949 | Sentence | denotes | Also, if the medication is abruptly ceased, there are chances that the patient may die due to hypertension instead of COVID-19. |
T251 | 950-1220 | Sentence | denotes | For this reason, it has been suggested that there is no need to stop the medication of a diabetic patient even though if he is affected by COVID-19 because there is no scientific evidence available conducted on human subjects regarding whether to use ACEi and ARBs [10]. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T183 | 18-35 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T184 | 50-67 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T185 | 341-358 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T186 | 363-375 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T187 | 738-755 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T188 | 916-928 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |