PMC:7242185 / 4342-6967
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T4 | 2067-2084 | Body_part | denotes | coronary arteries | http://purl.org/sig/ont/fma/fma3800 |
T5 | 2156-2160 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T6 | 2178-2193 | Body_part | denotes | coronary artery | http://purl.org/sig/ont/fma/fma49893 |
T7 | 2216-2222 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T8 | 2360-2370 | Body_part | denotes | troponin I | http://purl.org/sig/ont/fma/fma62340 |
T9 | 2360-2368 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 2067-2084 | Body_part | denotes | coronary arteries | http://purl.obolibrary.org/obo/UBERON_0001621 |
T2 | 2178-2193 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
T3 | 2187-2193 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/UBERON_0001637 |
T4 | 2216-2222 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T25 | 528-536 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T26 | 602-611 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T27 | 664-672 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T28 | 673-682 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T29 | 1089-1094 | Disease | denotes | STEMI | http://purl.obolibrary.org/obo/MONDO_0041656 |
T30 | 1148-1153 | Disease | denotes | STEMI | http://purl.obolibrary.org/obo/MONDO_0041656 |
T31 | 1196-1200 | Disease | denotes | COPD | http://purl.obolibrary.org/obo/MONDO_0005002 |
T32 | 1390-1395 | Disease | denotes | STEMI | http://purl.obolibrary.org/obo/MONDO_0041656 |
T33 | 1491-1496 | Disease | denotes | STEMI | http://purl.obolibrary.org/obo/MONDO_0041656 |
T34 | 1738-1741 | Disease | denotes | CAD | http://purl.obolibrary.org/obo/MONDO_0005010|http://purl.obolibrary.org/obo/MONDO_0018922 |
T36 | 1878-1881 | Disease | denotes | CKD | http://purl.obolibrary.org/obo/MONDO_0005300 |
T37 | 2002-2021 | Disease | denotes | Tako-Tsubo syndrome | http://purl.obolibrary.org/obo/MONDO_0019018 |
T38 | 2025-2046 | Disease | denotes | myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0005068 |
T39 | 2100-2119 | Disease | denotes | atrial fibrillation | http://purl.obolibrary.org/obo/MONDO_0004981 |
T40 | 2126-2149 | Disease | denotes | acute coronary syndrome | http://purl.obolibrary.org/obo/MONDO_0005542 |
T41 | 2173-2176 | Disease | denotes | CAD | http://purl.obolibrary.org/obo/MONDO_0005010|http://purl.obolibrary.org/obo/MONDO_0018922 |
T43 | 2178-2201 | Disease | denotes | coronary artery disease | http://purl.obolibrary.org/obo/MONDO_0005010 |
T44 | 2187-2201 | Disease | denotes | artery disease | http://purl.obolibrary.org/obo/MONDO_0000473 |
T45 | 2203-2206 | Disease | denotes | CKD | http://purl.obolibrary.org/obo/MONDO_0005300 |
T46 | 2208-2230 | Disease | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/MONDO_0005300 |
T47 | 2216-2230 | Disease | denotes | kidney disease | http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240 |
T49 | 2232-2275 | Disease | denotes | COPD, chronic obstructive pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005002 |
T50 | 2258-2275 | Disease | denotes | pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
T51 | 2448-2482 | Disease | denotes | ST-elevation myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0041656 |
T52 | 2461-2482 | Disease | denotes | myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0005068 |
T53 | 2583-2588 | Disease | denotes | STEMI | http://purl.obolibrary.org/obo/MONDO_0041656 |
T54 | 2590-2624 | Disease | denotes | ST-elevation myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0041656 |
T55 | 2603-2624 | Disease | denotes | myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0005068 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19 | 47-48 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T20 | 103-106 | http://purl.obolibrary.org/obo/CLO_0001002 | denotes | 162 |
T21 | 223-224 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T22 | 798-799 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T23 | 1106-1108 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
T24 | 1142-1144 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T25 | 1201-1203 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
T26 | 1348-1350 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
T27 | 1460-1462 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
T28 | 1659-1661 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T29 | 1742-1744 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
T30 | 1822-1824 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T31 | 1947-1950 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
T32 | 1962-1964 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
T33 | 2076-2084 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arteries |
T34 | 2076-2084 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arteries |
T35 | 2187-2193 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
T36 | 2187-2193 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | artery |
T37 | 2216-2222 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
T38 | 2216-2222 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
T39 | 2216-2222 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
T40 | 2448-2450 | http://purl.obolibrary.org/obo/CLO_0009141 | denotes | ST |
T41 | 2448-2450 | http://purl.obolibrary.org/obo/CLO_0050980 | denotes | ST |
T42 | 2590-2592 | http://purl.obolibrary.org/obo/CLO_0009141 | denotes | ST |
T43 | 2590-2592 | http://purl.obolibrary.org/obo/CLO_0050980 | denotes | ST |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T5 | 298-300 | Chemical | denotes | IR | http://purl.obolibrary.org/obo/CHEBI_74061 |
T6 | 333-335 | Chemical | denotes | IR | http://purl.obolibrary.org/obo/CHEBI_74061 |
T7 | 1031-1033 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T8 | 1058-1061 | Chemical | denotes | AGE | http://purl.obolibrary.org/obo/CHEBI_84123 |
T9 | 1819-1821 | Chemical | denotes | AF | http://purl.obolibrary.org/obo/CHEBI_73807 |
T10 | 2096-2098 | Chemical | denotes | AF | http://purl.obolibrary.org/obo/CHEBI_73807 |
T11 | 2448-2450 | Chemical | denotes | ST | http://purl.obolibrary.org/obo/CHEBI_141393 |
T12 | 2590-2592 | Chemical | denotes | ST | http://purl.obolibrary.org/obo/CHEBI_141393 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T5 | 602-611 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T6 | 1196-1200 | Phenotype | denotes | COPD | http://purl.obolibrary.org/obo/HP_0006510 |
T7 | 1264-1276 | Phenotype | denotes | HYPERTENSION | http://purl.obolibrary.org/obo/HP_0000822 |
T8 | 1542-1554 | Phenotype | denotes | DYSLIPIDEMIA | http://purl.obolibrary.org/obo/HP_0003119 |
T9 | 2025-2046 | Phenotype | denotes | myocardial infarction | http://purl.obolibrary.org/obo/HP_0001658 |
T10 | 2100-2119 | Phenotype | denotes | atrial fibrillation | http://purl.obolibrary.org/obo/HP_0005110 |
T11 | 2208-2230 | Phenotype | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/HP_0012622 |
T12 | 2232-2236 | Phenotype | denotes | COPD | http://purl.obolibrary.org/obo/HP_0006510 |
T13 | 2238-2275 | Phenotype | denotes | chronic obstructive pulmonary disease | http://purl.obolibrary.org/obo/HP_0006510 |
T14 | 2461-2482 | Phenotype | denotes | myocardial infarction | http://purl.obolibrary.org/obo/HP_0001658 |
T15 | 2603-2624 | Phenotype | denotes | myocardial infarction | http://purl.obolibrary.org/obo/HP_0001658 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 732-753 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | reverse transcription |
T2 | 740-753 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T31 | 0-46 | Sentence | denotes | Patient characteristics are shown in Table 1 . |
T32 | 47-198 | Sentence | denotes | A total of 246 ACS-patients were included in the study (162 patients with ACS admitted in March 2019, and 84 patients with ACS admitted in March 2020). |
T33 | 199-469 | Sentence | denotes | During the case period, a total of 84 hospital admissions for ACS were observed, accounting for an IR of 2.7 admissions per day vs an IR of 5.2 admissions per day observed in the control period (odds ratio [OR], 0.52; 95% confidence interval [CI], 0.39-0.67; P < 0.001). |
T34 | 470-877 | Sentence | denotes | Of the 84 patients with ACS in 2020, 26 were positive for COVID-19; of these, 5 patients were already hospitalized for interstitial pneumonia, whereas—in the remaining 21 cases—the diagnosis of COVID-19 infection was an incidental finding from the routine COVID reverse transcription polymerase chain reaction (RT-PCR) assay of a nasal swab performed immediately at admission before cardiac catheterization. |
T35 | 878-946 | Sentence | denotes | Table 1 Patients clinical characteristics and acute clinical outcome |
T36 | 947-1057 | Sentence | denotes | Group 2019162 patients Group 202084 patients P value Group I 2019162 patients Group II 202084 patients P value |
T37 | 1058-1119 | Sentence | denotes | AGE 69.9 + 32.6 68.3 + 30.9 ns STEMI 59 (36.4%) 34 (40.5%) ns |
T38 | 1120-1195 | Sentence | denotes | SEX M:113/F:49 M:62/F:22 ns STEMI rr > 24 hours 7 (4.3%) 15 (17.8%) < 0.001 |
T39 | 1196-1263 | Sentence | denotes | COPD 35 (21.6%) 7 (8.3%) < 0.01 NSTEMI 93 (57.4%) 33 (39.3%) < 0.01 |
T40 | 1264-1338 | Sentence | denotes | HYPERTENSION 108 (66.7%) 65 (77.4%) ns Others ACS 3 (1.9%) 2 (2.4%) < 0.01 |
T41 | 1339-1440 | Sentence | denotes | DIABETES 48 (29.6%) 31 (36.9%) ns Door to balloon (STEMI) 40 + 12 (minutes) 66 + 17 (minutes) < 0.001 |
T42 | 1441-1541 | Sentence | denotes | SMOKING 85 (52.5%) 34 (40.5%) ns Symptoms to PCI (STEMI) 3.9 + 2.2 (hours) 5.8 + 3.1 (hours) < 0.001 |
T43 | 1542-1649 | Sentence | denotes | DYSLIPIDEMIA 100 (61.7%) 58 (69%) ns Symptoms to PCI (NSTEMI) 18.8 + 20 (hours) 36.9 + 38.4 (hours) < 0.001 |
T44 | 1650-1731 | Sentence | denotes | BMI > 30 36 (22.2%) 23 (27.4%) ns hs-cTnI (basal) 1142 + 4017 5138 + 9408 < 0.001 |
T45 | 1732-1818 | Sentence | denotes | KNOWN CAD 41 (25.3%) 31 (36.9%) ns hs-cTnI (peak) 9143 + 13,825 13,681 + 10,936 < 0.01 |
T46 | 1819-1877 | Sentence | denotes | AF 18 (11.1%) 6 (7.1%) ns LVEF 48.9 + 9.4 45.9 + 12 < 0.05 |
T47 | 1878-1934 | Sentence | denotes | CKD 21 (13%) 12 (14.3%) ns LVEF < 40% 24.7% 42.8% < 0.01 |
T48 | 1935-1990 | Sentence | denotes | GRACE SCORE 116 + 26 126 + 27 < 0.01 Death 1.8% 4.7% ns |
T49 | 1991-2095 | Sentence | denotes | Other ACS (Tako-Tsubo syndrome or myocardial infarction with nonobstructive coronary arteries [MINOCA]). |
T50 | 2096-2625 | Sentence | denotes | AF, atrial fibrillation; ACS, acute coronary syndrome; BMI, body mass index; CAD, coronary artery disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; GRACE, Global Registry of Acute Coronary Events; hs-cTnI, high-sensitivity cardiac troponin I (lab range 0-58 ng/L); LVEF, left-ventricular ejection fraction; NSTEMI, non–ST-elevation myocardial infarction; rr, recommended reperfusion; PCI, percutaneous coronary intervention; rr, recommended reperfusion; STEMI, ST-elevation myocardial infarction. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
62 | 1687-1691 | Gene | denotes | cTnI | Gene:7137 |
63 | 1770-1774 | Gene | denotes | cTnI | Gene:7137 |
64 | 1310-1315 | Gene | denotes | ACS 3 | Gene:7291 |
65 | 961-969 | Species | denotes | patients | Tax:9606 |
66 | 983-991 | Species | denotes | patients | Tax:9606 |
67 | 1016-1024 | Species | denotes | patients | Tax:9606 |
68 | 1041-1049 | Species | denotes | patients | Tax:9606 |
69 | 1196-1200 | Disease | denotes | COPD | MESH:D029424 |
70 | 1339-1347 | Disease | denotes | DIABETES | MESH:D003920 |
71 | 1819-1821 | Disease | denotes | AF | MESH:D001281 |
72 | 1878-1881 | Disease | denotes | CKD | MESH:D012080 |
73 | 1972-1977 | Disease | denotes | Death | MESH:D003643 |
75 | 886-894 | Species | denotes | Patients | Tax:9606 |
78 | 2002-2021 | Disease | denotes | Tako-Tsubo syndrome | MESH:D054549 |
79 | 2025-2046 | Disease | denotes | myocardial infarction | MESH:D009203 |
91 | 2329-2333 | Gene | denotes | cTnI | Gene:7137 |
92 | 2096-2098 | Disease | denotes | AF | MESH:D001281 |
93 | 2100-2119 | Disease | denotes | atrial fibrillation | MESH:D001281 |
94 | 2126-2149 | Disease | denotes | acute coronary syndrome | MESH:D054058 |
95 | 2178-2201 | Disease | denotes | coronary artery disease | MESH:D003324 |
96 | 2203-2206 | Disease | denotes | CKD | MESH:D012080 |
97 | 2208-2230 | Disease | denotes | chronic kidney disease | MESH:D051436 |
98 | 2232-2236 | Disease | denotes | COPD | MESH:D029424 |
99 | 2238-2275 | Disease | denotes | chronic obstructive pulmonary disease | MESH:D029424 |
100 | 2461-2482 | Disease | denotes | myocardial infarction | MESH:D009203 |
101 | 2603-2624 | Disease | denotes | myocardial infarction | MESH:D009203 |
113 | 0-7 | Species | denotes | Patient | Tax:9606 |
114 | 66-74 | Species | denotes | patients | Tax:9606 |
115 | 107-115 | Species | denotes | patients | Tax:9606 |
116 | 156-164 | Species | denotes | patients | Tax:9606 |
117 | 480-488 | Species | denotes | patients | Tax:9606 |
118 | 550-558 | Species | denotes | patients | Tax:9606 |
119 | 528-536 | Disease | denotes | COVID-19 | MESH:C000657245 |
120 | 602-611 | Disease | denotes | pneumonia | MESH:D011014 |
121 | 664-672 | Disease | denotes | COVID-19 | MESH:C000657245 |
122 | 673-682 | Disease | denotes | infection | MESH:D007239 |
123 | 726-731 | Disease | denotes | COVID | MESH:C000657245 |