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PMC:7242007 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 0-10 Species denotes SARS‐CoV‐2 Tax:2697049
3 44-82 Disease denotes Hepatitis B and Hepatitis C Infections MESH:D006509
5 200-208 Disease denotes COVID‐19 MESH:C000657245
7 209-233 Disease denotes coronavirus disease 2019 MESH:C000657245
9 264-281 Disease denotes hepatitis B virus MESH:D006509
11 286-303 Disease denotes hepatitis C virus MESH:D006526
13 314-336 Disease denotes immunodeficiency virus MESH:D007153
15 361-365 Disease denotes PWID
42 464-511 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
43 513-523 Species denotes SARS‐CoV‐2 Tax:2697049
44 711-721 Species denotes SARS‐CoV‐2 Tax:2697049
45 1371-1379 Species denotes patients Tax:9606
46 1417-1445 Species denotes human immunodeficiency virus Tax:12721
47 1453-1470 Species denotes hepatitis B virus Tax:10407
48 1586-1596 Species denotes SARS‐CoV‐2 Tax:2697049
49 1688-1694 Species denotes people Tax:9606
50 1447-1450 Species denotes HIV Tax:12721
51 1472-1475 Species denotes HBV Tax:10407
52 641-650 Disease denotes mortality MESH:D003643
53 652-676 Disease denotes Coronavirus disease 2019 MESH:C000657245
54 678-686 Disease denotes COVID‐19 MESH:C000657245
55 909-917 Disease denotes infected MESH:D007239
56 1040-1059 Disease denotes acute liver failure MESH:D017114
57 1213-1234 Disease denotes ischemic liver injury MESH:D056486
58 1252-1264 Disease denotes liver injury MESH:D017093
59 1279-1291 Disease denotes liver injury MESH:D017093
60 1397-1407 Disease denotes infections MESH:D007239
61 1482-1515 Disease denotes hepatitis C virus (HCV) infection MESH:D006526
62 1536-1549 Disease denotes co‐infections MESH:D060085
63 1606-1616 Disease denotes infections MESH:D007239
64 1632-1646 Disease denotes liver diseases MESH:D008107
65 1713-1718 Disease denotes PWIDs
66 1820-1828 Disease denotes COVID‐19 MESH:C000657245
67 1924-1934 Disease denotes infections MESH:D007239
99 2621-2629 Species denotes patients Tax:9606
100 2740-2748 Species denotes patients Tax:9606
101 2811-2818 Species denotes patient Tax:9606
102 2877-2885 Species denotes patients Tax:9606
103 3049-3057 Species denotes patients Tax:9606
104 3159-3167 Species denotes patients Tax:9606
105 3495-3505 Species denotes SARS‐CoV‐2 Tax:2697049
106 2185-2188 Species denotes HBV Tax:10407
107 2193-2196 Species denotes HCV Tax:11103
108 2447-2450 Species denotes HCV Tax:11103
109 2455-2458 Species denotes HBV Tax:10407
110 3129-3132 Species denotes HBV Tax:10407
111 3146-3149 Species denotes HBV Tax:10407
112 3348-3351 Species denotes HBV Tax:10407
113 3186-3195 Chemical denotes bilirubin MESH:D001663
114 2056-2069 Disease denotes liver disease MESH:D008107
115 2084-2092 Disease denotes COVID‐19 MESH:C000657245
116 2158-2180 Disease denotes HBV and HCV infections MESH:D006526
117 2209-2219 Disease denotes infections MESH:D007239
118 2336-2344 Disease denotes COVID‐19 MESH:C000657245
119 2409-2429 Disease denotes SARS‐CoV‐2 infection MESH:C000657245
120 2483-2491 Disease denotes COVID‐19 MESH:C000657245
121 2537-2559 Disease denotes HBV and HCV infections MESH:D006526
122 2635-2643 Disease denotes COVID‐19 MESH:C000657245
123 2679-2701 Disease denotes HBV and HCV infections MESH:D006526
124 2891-2903 Disease denotes HBV infected MESH:D006509
125 3063-3071 Disease denotes COVID‐19 MESH:C000657245
126 3076-3089 Disease denotes HBV infection MESH:D006509
127 3274-3283 Disease denotes mortality MESH:D003643
128 3454-3462 Disease denotes COVID‐19 MESH:C000657245
129 3530-3543 Disease denotes HBV infection MESH:D006509
225 3735-3743 Species denotes patients Tax:9606
226 3812-3820 Species denotes patients Tax:9606
227 3961-3969 Species denotes patients Tax:9606
228 4358-4366 Species denotes patients Tax:9606
229 4502-4510 Species denotes patients Tax:9606
230 4550-4558 Species denotes patients Tax:9606
231 4631-4641 Species denotes SARS‐CoV‐2 Tax:2697049
232 4701-4709 Species denotes patients Tax:9606
233 4790-4798 Species denotes patients Tax:9606
234 4883-4891 Species denotes patients Tax:9606
235 4934-4942 Species denotes patients Tax:9606
236 5101-5109 Species denotes patients Tax:9606
237 5191-5199 Species denotes patients Tax:9606
238 5256-5264 Species denotes patients Tax:9606
239 5419-5427 Species denotes patients Tax:9606
240 5540-5548 Species denotes patients Tax:9606
241 5587-5595 Species denotes patients Tax:9606
242 5738-5746 Species denotes patients Tax:9606
243 5778-5786 Species denotes patients Tax:9606
244 6153-6163 Species denotes SARS‐CoV‐2 Tax:2697049
245 6176-6183 Species denotes patient Tax:9606
246 6327-6334 Species denotes patient Tax:9606
247 6356-6366 Species denotes SARS‐CoV‐2 Tax:2697049
248 6615-6623 Species denotes patients Tax:9606
249 6645-6655 Species denotes SARS‐CoV‐2 Tax:2697049
250 6659-6665 Species denotes Turkey Tax:9103
251 6790-6797 Species denotes patient Tax:9606
252 6926-6934 Species denotes patients Tax:9606
253 7017-7024 Species denotes patient Tax:9606
254 7049-7059 Species denotes SARS‐CoV‐2 Tax:2697049
255 3691-3694 Species denotes HBV Tax:10407
256 3826-3829 Species denotes HBV Tax:10407
257 3873-3876 Species denotes HBV Tax:10407
258 4011-4014 Species denotes HBV Tax:10407
259 4161-4164 Species denotes HBV Tax:10407
260 4187-4190 Species denotes HBV Tax:10407
261 4564-4567 Species denotes HBV Tax:10407
262 5068-5071 Species denotes HCV Tax:11103
263 5205-5208 Species denotes HCV Tax:11103
264 5236-5239 Species denotes HCV Tax:11103
265 5326-5329 Species denotes HCV Tax:11103
266 5433-5436 Species denotes HCV Tax:11103
267 5487-5490 Species denotes HIV Tax:12721
268 5601-5604 Species denotes HIV Tax:12721
269 6149-6152 Species denotes HIV Tax:12721
270 6256-6259 Species denotes HIV Tax:12721
271 6352-6355 Species denotes HIV Tax:12721
272 6641-6644 Species denotes HIV Tax:12721
273 6911-6914 Species denotes HIV Tax:12721
274 6965-6968 Species denotes HCV Tax:11103
275 6969-6972 Species denotes HIV Tax:12721
276 7115-7118 Species denotes HIV Tax:12721
277 6494-6503 Chemical denotes lopinavir MESH:D061466
278 3605-3614 Disease denotes Infection MESH:D007239
279 3749-3757 Disease denotes COVID‐19 MESH:C000657245
280 4028-4037 Disease denotes mortality MESH:D003643
281 4104-4117 Disease denotes HBV infection MESH:D006509
282 4121-4129 Disease denotes COVID‐19 MESH:C000657245
283 4169-4174 Disease denotes COVID MESH:C000657245
284 4227-4235 Disease denotes COVID‐19 MESH:C000657245
285 4298-4306 Disease denotes COVID‐19 MESH:C000657245
286 4345-4357 Disease denotes HBV‐infected MESH:D006509
287 4386-4399 Disease denotes cirrhosis Zha MESH:D005355
288 4516-4524 Disease denotes COVID‐19 MESH:C000657245
289 4603-4616 Disease denotes HBV infection MESH:D006509
290 4715-4723 Disease denotes COVID‐19 MESH:C000657245
291 4804-4816 Disease denotes HBV infected MESH:D006509
292 4897-4905 Disease denotes COVID‐19 MESH:C000657245
293 4948-4973 Disease denotes HBV infected HBV‐infected MESH:D006509
294 5115-5123 Disease denotes COVID‐19 MESH:C000657245
295 5209-5217 Disease denotes infected MESH:D007239
296 5270-5275 Disease denotes COVID MESH:C000657245
297 5333-5341 Disease denotes COVID‐19 MESH:C000657245
298 5372-5380 Disease denotes COVID‐19 MESH:C000657245
299 5459-5475 Disease denotes cirrhosis Blanco MESH:D005355
300 5531-5539 Disease denotes COVID‐19 MESH:C000657245
301 5792-5800 Disease denotes COVID‐19 MESH:C000657245
302 5874-5882 Disease denotes COVID‐19 MESH:C000657245
303 5886-5891 Disease denotes PWIDs
304 6008-6041 Disease denotes renal insufficiency Heterogeneous MESH:D007674
305 6167-6175 Disease denotes infected MESH:D007239
306 6194-6202 Disease denotes diabetes MESH:D003920
307 6338-6346 Disease denotes infected MESH:D007239
308 6378-6386 Disease denotes COVID‐19 MESH:C000657245
309 6387-6416 Disease denotes pneumonia Had ongoing ART HIV MESH:D015658
310 6468-6476 Disease denotes COVID‐19 MESH:C000657245
311 6504-6531 Disease denotes ritonavir Shortened disease MESH:D003141
312 6563-6580 Disease denotes pulmonary lesions MESH:D008171
313 6624-6635 Disease denotes co‐infected MESH:D060085
314 6708-6716 Disease denotes COVID‐19 MESH:C000657245
315 6717-6726 Disease denotes infection MESH:D007239
316 6806-6838 Disease denotes sudden cardiac arrest Resolution MESH:D016757
317 6940-6948 Disease denotes COVID‐19 MESH:C000657245
318 6997-7016 Disease denotes HIV/HCV co‐infected MESH:D060085
319 7030-7038 Disease denotes COVID‐19 MESH:C000657245
323 3554-3564 Species denotes SARS‐CoV‐2 Tax:2697049
324 3565-3573 Disease denotes COVID‐19 MESH:C000657245
325 3578-3589 Disease denotes Hepatitis B MESH:D006509
352 7543-7551 Species denotes patients Tax:9606
353 7635-7643 Species denotes patients Tax:9606
354 7734-7742 Species denotes patients Tax:9606
355 7821-7824 Species denotes men Tax:9606
356 7843-7846 Species denotes men Tax:9606
357 8140-8148 Species denotes patients Tax:9606
358 8285-8295 Species denotes SARS‐CoV‐2 Tax:2697049
359 8486-8496 Species denotes SARS‐CoV‐2 Tax:2697049
360 7901-7904 Species denotes HIV Tax:12721
361 8050-8053 Species denotes HIV Tax:12721
362 8058-8061 Species denotes HCV Tax:11103
363 7531-7539 Disease denotes COVID‐19 MESH:C000657245
364 7557-7570 Disease denotes HIV infection MESH:D015658
365 7649-7657 Disease denotes COVID‐19 MESH:C000657245
366 7669-7681 Disease denotes HIV‐infected MESH:D015658
367 7755-7768 Disease denotes HIV infection MESH:D015658
368 7914-7922 Disease denotes COVID‐19 MESH:C000657245
369 7950-7959 Disease denotes mortality MESH:D003643
370 8015-8023 Disease denotes COVID‐19 MESH:C000657245
371 8033-8044 Disease denotes co‐infected MESH:D060085
372 8099-8139 Disease denotes HIV mono‐infected or HIV/HCV co‐infected MESH:D015658
373 8420-8428 Disease denotes COVID‐19 MESH:C000657245
374 8432-8437 Disease denotes PWIDs
375 8541-8557 Disease denotes viral infections MESH:D001102
376 8559-8572 Disease denotes heart disease MESH:D006331
377 8578-8591 Disease denotes renal disease MESH:D007674
407 9548-9556 Species denotes patients Tax:9606
408 8688-8691 Species denotes HBV Tax:10407
409 8696-8699 Species denotes HCV Tax:11103
410 8960-8963 Species denotes HCV Tax:11103
411 9001-9004 Species denotes HCV Tax:11103
412 9409-9412 Species denotes HCV Tax:11103
413 9562-9565 Species denotes HBV Tax:10407
414 9611-9614 Species denotes HBV Tax:10407
415 9742-9745 Species denotes HBV Tax:10407
416 9843-9846 Species denotes HBV Tax:10407
417 9918-9921 Species denotes HBV Tax:10407
418 10015-10018 Species denotes HBV Tax:10407
419 9660-9671 Chemical denotes tocilizumab MESH:C502936
420 9767-9778 Chemical denotes tocilizumab MESH:C502936
421 9783-9793 Chemical denotes prednisone MESH:D011241
422 8632-8654 Disease denotes HBV and HCV infections MESH:D006526
423 8735-8755 Disease denotes SARS‐CoV‐2 infection MESH:C000657245
424 8760-8768 Disease denotes COVID‐19 MESH:C000657245
425 8889-8903 Disease denotes Liver Diseases MESH:D008107
426 9025-9045 Disease denotes SARS‐CoV‐2 infection MESH:C000657245
427 9132-9140 Disease denotes COVID‐19 MESH:C000657245
428 9314-9322 Disease denotes COVID‐19 MESH:C000657245
429 9365-9378 Disease denotes HCV infection MESH:D006526
430 9439-9447 Disease denotes COVID‐19 MESH:C000657245
431 9716-9724 Disease denotes COVID‐19 MESH:C000657245
432 10069-10077 Disease denotes COVID‐19 MESH:C000657245
433 10143-10151 Disease denotes COVID‐19 MESH:C000657245
434 10191-10204 Disease denotes liver disease MESH:D008107
435 10438-10446 Disease denotes COVID‐19 MESH:C000657245
443 10455-10465 Species denotes SARS‐CoV‐2 Tax:2697049
444 10564-10574 Species denotes SARS‐CoV‐2 Tax:2697049
445 10498-10501 Species denotes HBV Tax:10407
446 10506-10509 Species denotes HCV Tax:11103
447 10470-10478 Disease denotes COVID‐19 MESH:C000657245
448 10511-10519 Disease denotes COVID‐19 MESH:C000657245
449 10534-10553 Disease denotes respiratory illness MESH:D012140

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 19-24 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T2 304-307 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T3 1046-1051 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T4 1222-1227 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T5 1252-1257 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T6 1279-1284 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T7 1447-1450 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T8 1632-1637 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T9 1837-1842 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T10 2056-2061 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T11 5487-5490 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T12 5601-5604 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T13 5805-5808 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T14 5970-5983 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T15 6058-6066 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T16 6149-6152 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T17 6220-6228 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T18 6256-6259 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T19 6352-6355 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T20 6413-6416 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T21 6641-6644 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T22 6876-6884 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T23 6911-6914 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T24 6969-6972 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T25 6997-7000 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T26 7060-7063 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T27 7081-7089 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T28 7115-7118 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T29 7557-7560 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T30 7669-7672 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T31 7755-7758 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T32 7901-7904 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T33 8050-8053 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T34 8099-8102 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T35 8120-8123 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T36 8264-8272 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T37 8559-8564 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T38 8889-8894 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T39 9213-9218 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T40 9281-9285 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T41 9289-9293 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T42 10191-10196 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 19-24 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T2 1046-1051 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T3 1222-1227 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T4 1252-1257 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T5 1279-1284 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T6 1632-1637 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T7 1837-1842 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T8 2056-2061 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T9 5970-5983 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T10 8559-8564 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T11 8889-8894 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T12 9213-9218 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T13 9281-9285 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T14 9289-9293 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T15 10191-10196 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 0-4 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T2 44-55 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T3 44-53 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T4 60-71 Disease denotes Hepatitis C http://purl.obolibrary.org/obo/MONDO_0005231
T5 60-69 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T6 83-87 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T7 98-109 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T8 98-107 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T9 200-208 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 209-233 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T11 234-237 Disease denotes DDI http://purl.obolibrary.org/obo/MONDO_0007436
T12 264-275 Disease denotes hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T13 264-273 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T14 286-297 Disease denotes hepatitis C http://purl.obolibrary.org/obo/MONDO_0005231
T15 286-295 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T16 314-330 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T17 391-395 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 402-449 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T19 402-435 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T20 464-511 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T21 464-497 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T22 513-517 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 652-676 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T24 678-686 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 711-715 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T26 1040-1059 Disease denotes acute liver failure http://purl.obolibrary.org/obo/MONDO_0019542
T27 1228-1234 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T28 1258-1264 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T29 1266-1291 Disease denotes drug‐induced liver injury http://purl.obolibrary.org/obo/MONDO_0005359
T30 1285-1291 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T31 1397-1407 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T32 1423-1439 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T33 1453-1464 Disease denotes hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T34 1453-1462 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T35 1482-1493 Disease denotes hepatitis C http://purl.obolibrary.org/obo/MONDO_0005231
T36 1482-1491 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T37 1506-1515 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T38 1539-1549 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T39 1586-1590 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T40 1606-1616 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T41 1632-1646 Disease denotes liver diseases http://purl.obolibrary.org/obo/MONDO_0005154
T42 1820-1828 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 1918-1934 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T44 2056-2069 Disease denotes liver disease http://purl.obolibrary.org/obo/MONDO_0005154
T45 2084-2092 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 2170-2180 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T47 2209-2219 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T48 2336-2344 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 2409-2413 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T50 2420-2429 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T51 2483-2491 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 2549-2562 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T53 2635-2643 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 2691-2701 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T55 3063-3071 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T56 3080-3089 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T57 3454-3462 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T58 3495-3499 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T59 3534-3543 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 3554-3558 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T61 3565-3573 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 3578-3589 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T63 3578-3587 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T64 3605-3614 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 3749-3757 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 4108-4117 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T67 4121-4129 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 4169-4177 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 4227-4235 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 4298-4306 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 4386-4395 Disease denotes cirrhosis http://purl.obolibrary.org/obo/MONDO_0005155
T72 4516-4524 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 4607-4616 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T74 4631-4635 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T75 4715-4723 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 4897-4905 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 5115-5123 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 5270-5278 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T79 5333-5341 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T80 5372-5380 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T81 5459-5468 Disease denotes cirrhosis http://purl.obolibrary.org/obo/MONDO_0005155
T82 5531-5539 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T83 5792-5800 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 5874-5882 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 6008-6027 Disease denotes renal insufficiency http://purl.obolibrary.org/obo/MONDO_0001106
T86 6153-6157 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T87 6194-6202 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T88 6356-6360 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T89 6378-6386 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T90 6387-6396 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T91 6468-6476 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 6645-6649 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T93 6708-6716 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 6717-6726 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T95 6806-6827 Disease denotes sudden cardiac arrest http://purl.obolibrary.org/obo/MONDO_0007264
T96 6813-6827 Disease denotes cardiac arrest http://purl.obolibrary.org/obo/MONDO_0000745
T97 6940-6948 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T98 7030-7038 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 7049-7053 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T100 7228-7236 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T101 7531-7539 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T102 7557-7570 Disease denotes HIV infection http://purl.obolibrary.org/obo/MONDO_0005109
T103 7561-7570 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T104 7649-7657 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 7755-7768 Disease denotes HIV infection http://purl.obolibrary.org/obo/MONDO_0005109
T106 7759-7768 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T107 7914-7922 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T108 8015-8023 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 8285-8289 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T110 8420-8428 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T111 8486-8490 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T112 8541-8557 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T113 8559-8572 Disease denotes heart disease http://purl.obolibrary.org/obo/MONDO_0005267
T114 8578-8591 Disease denotes renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T116 8644-8654 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T117 8735-8739 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T118 8746-8755 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T119 8760-8768 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 9025-9029 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T121 9036-9045 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T122 9132-9140 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 9314-9322 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T124 9369-9378 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T125 9439-9447 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 9716-9724 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 10069-10077 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 10143-10151 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T129 10191-10204 Disease denotes liver disease http://purl.obolibrary.org/obo/MONDO_0005154
T130 10438-10446 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T131 10455-10459 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T132 10470-10478 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 10511-10519 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 10564-10568 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 19-24 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T2 19-24 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T3 54-55 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T4 108-109 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T5 274-275 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T6 276-281 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T7 298-303 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T8 308-313 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T9 331-336 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T10 525-530 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T11 531-534 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T12 588-591 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T13 597-598 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 723-726 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T15 1014-1019 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T16 1046-1051 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T17 1046-1051 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T18 1144-1145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 1174-1175 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 1193-1194 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 1222-1227 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T22 1222-1227 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T23 1252-1257 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T24 1252-1257 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T25 1279-1284 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T26 1279-1284 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T27 1296-1297 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 1330-1335 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T29 1337-1343 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3 , 4
T30 1417-1422 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T31 1440-1445 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T32 1463-1464 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T33 1465-1470 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T34 1494-1499 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T35 1632-1637 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T36 1632-1637 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T37 1837-1842 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T38 1837-1842 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T39 1950-1951 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T40 2013-2016 http://purl.obolibrary.org/obo/CLO_0001577 denotes a 3
T41 2056-2061 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T42 2056-2061 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T43 2372-2375 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T44 2492-2495 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T45 2585-2586 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 2790-2791 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 2973-2974 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T48 3095-3096 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T49 3214-3215 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 3265-3266 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51 3325-3327 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T52 3335-3336 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 3588-3589 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T54 3761-3762 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 3839-3840 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T56 3887-3888 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 4019-4020 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 4407-4409 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T59 5552-5553 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 5909-5912 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T61 5970-5983 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T62 6147-6148 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 6237-6241 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T64 6325-6326 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 6659-6665 http://purl.obolibrary.org/obo/NCBITaxon_9005 denotes Turkey
T66 7064-7068 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T67 7594-7595 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T68 8439-8440 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 8559-8564 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T70 8559-8564 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T71 8559-8564 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T72 8559-8564 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T73 8824-8829 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T74 8889-8894 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T75 8889-8894 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T76 9023-9024 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77 9141-9151 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T78 9213-9218 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T79 9213-9218 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T80 9219-9226 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T81 9281-9285 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T82 9289-9293 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T83 9296-9298 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T84 9344-9345 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 9427-9428 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 9448-9451 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T87 9794-9797 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T88 9870-9871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 10191-10196 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T90 10191-10196 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 234-237 Chemical denotes DDI http://purl.obolibrary.org/obo/CHEBI_490877
T2 238-242 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T3 243-247 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T4 385-390 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T5 1266-1270 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T6 1706-1711 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T7 3186-3195 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990
T8 3435-3450 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T9 3931-3940 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990
T10 4247-4258 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T11 4260-4275 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T12 4461-4475 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T13 5712-5730 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T15 5721-5730 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T16 6229-6236 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T17 6428-6437 Chemical denotes tenofovir http://purl.obolibrary.org/obo/CHEBI_134504|http://purl.obolibrary.org/obo/CHEBI_63625|http://purl.obolibrary.org/obo/CHEBI_63716
T20 6439-6449 Chemical denotes lamivudine http://purl.obolibrary.org/obo/CHEBI_63577
T21 6451-6460 Chemical denotes efavirenz http://purl.obolibrary.org/obo/CHEBI_119486
T22 6494-6513 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T23 6494-6503 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T24 6504-6513 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T25 8224-8228 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T26 8229-8233 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T27 9660-9671 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T28 9676-9691 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T29 9767-9778 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T30 9783-9793 Chemical denotes prednisone http://purl.obolibrary.org/obo/CHEBI_8382

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 1918-1934 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T2 6885-6894 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T3 8541-8557 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-25 Sentence denotes SARS‐CoV‐2 and the Liver:
T2 26-82 Sentence denotes Considerations in Hepatitis B and Hepatitis C Infections
T3 83-115 Sentence denotes SARS‐CoV‐2 and Hepatitis B and C
T4 116-121 Sentence denotes Reddy
T5 123-158 Sentence denotes Watch the interview with the author
T6 159-172 Sentence denotes Abbreviations
T7 173-199 Sentence denotes ART antiretroviral therapy
T8 200-233 Sentence denotes COVID‐19 coronavirus disease 2019
T9 234-259 Sentence denotes DDI drug‐drug interaction
T10 260-281 Sentence denotes HBV hepatitis B virus
T11 282-303 Sentence denotes HCV hepatitis C virus
T12 304-336 Sentence denotes HIV human immunodeficiency virus
T13 337-360 Sentence denotes ICU intensive care unit
T14 361-390 Sentence denotes PWID person who injects drugs
T15 391-449 Sentence denotes SARS‐CoV‐2 severe acute respiratory syndrome coronavirus 2
T16 450-651 Sentence denotes Globally, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus has variably affected the various parts of the world and has been a major cause for significant morbidity and mortality.
T17 652-842 Sentence denotes Coronavirus disease 2019 (COVID‐19), the disease caused by SARS‐CoV‐2, has been reported to have multiple clinical manifestations, although primarily they have been pulmonary manifestations.
T18 843-930 Sentence denotes Hepatic manifestations have variably been present in up to 50% of infected individuals.
T19 931-1060 Sentence denotes 1 , 2 The spectrum ranges from asymptomatic abnormalities in hepatic biochemical tests to the rare case of acute liver failure.
T20 1061-1336 Sentence denotes The cause for hepatic manifestations is unclear at this stage and may be caused by a variety of reasons, such as a manifestation of a systemic illness, ischemic liver injury, immune‐mediated liver injury, drug‐induced liver injury, or a direct cytopathic effect of the virus.
T21 1337-1658 Sentence denotes 3 , 4 , 5 , 6 Not uncommonly, patients have concomitant infections, such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infection, either alone or as co‐infections, and the impact of the pandemic and SARS‐CoV‐2 on these infections and associated liver diseases is unknown.
T22 1659-1734 Sentence denotes Further, the implications in people who inject drugs (PWIDs) may be unique.
T23 1735-1949 Sentence denotes Observations continue to evolve regarding hepatic manifestations and challenges with COVID‐19 and the liver, and as such, expectations and guidance on issues relevant to the multiple viral infections are important.
T24 1950-2181 Sentence denotes A meta‐analysis, primarily involving reports from China, noted a 3% prevalence rate of underlying chronic liver disease in those with COVID‐19, although it does not provide specific data on the prevalence of HBV and HCV infections.
T25 2182-2359 Sentence denotes 7 HBV and HCV are chronic infections that are frequently encountered worldwide, and the former is particularly common in China, where the first cases of COVID‐19 were reported.
T26 2360-2459 Sentence denotes Thus, there has been concern about the impact of SARS‐CoV‐2 infection on the course of HCV and HBV.
T27 2460-2581 Sentence denotes Thus far, fortunately, COVID‐19 has been reported infrequently in those with HBV and HCV infections in the United States.
T28 2582-2776 Sentence denotes In a large series of 5700 hospitalized patients with COVID‐19 in the northeastern United States, HBV and HCV infections were encountered in 0.1% and <0.1% of patients, respectively 8 (Table 1).
T29 2777-2969 Sentence denotes In contrast, a large hospitalized patient series from Wuhan, China, observed that 2.1% (23/1099) of patients were HBV infected and represented 2.4% of nonsevere cases and 0.6% of severe cases.
T30 2970-3309 Sentence denotes 9 A single‐center retrospective study from China noted that 12.2% (15/123) of patients with COVID‐19 had HBV infection, and a higher percentage with comorbid HBV, relative to HBV‐negative patients, had higher total bilirubin levels, developed a more severe course (46.7% versus 24.1%), and had a higher mortality rate (13.3% versus 2.8%).
T31 3310-3324 Sentence denotes 10 Zha et al.
T32 3325-3544 Sentence denotes 11 noted a background HBV prevalence rate of 6.5% (2/31) while reporting on their experience with the use of corticosteroids in COVID‐19; further, they observed delayed SARS‐CoV‐2 clearance in those with HBV infection.
T33 3545-3595 Sentence denotes Table 1 SARS‐CoV‐2/COVID‐19 and Hepatitis B and C
T34 3596-3674 Sentence denotes Authors Infection Study Characteristics Observations Unique Considerations
T35 3675-3686 Sentence denotes Chen et al.
T36 3687-3838 Sentence denotes 10 HBV Retrospective analysis of hospitalized patients with COVID‐19 in a single center in Wuhan, China 12.2% (15/123) of patients were HBV infected
T37 3839-3924 Sentence denotes A higher percentage with comorbid HBV developed a severe outcome (46.7% versus 24.1%)
T38 3925-3987 Sentence denotes Total bilirubin level was higher in patients with comorbid HBV
T39 3988-4177 Sentence denotes Patients with comorbid HBV had a higher mortality rate (13.3% versus 2.8%) Heterogeneous data on the prevalence of HBV infection in COVID‐19 and on the interaction between HBV and COVID‐19
T40 4178-4276 Sentence denotes Risk for HBV reactivation with some experimental COVID‐19 therapies (tocilizumab, corticosteroids)
T41 4277-4395 Sentence denotes Some investigational COVID‐19 medications may be contraindicated in HBV‐infected patients with decompensated cirrhosis
T42 4396-4406 Sentence denotes Zha et al.
T43 4407-4576 Sentence denotes 11 Observational study investigating the efficacy of corticosteroid treatment in hospitalized patients with COVID‐19 in China 6.5% (2/31) of patients were HBV infected
T44 4577-4651 Sentence denotes Association found between HBV infection and prolonged SARS‐CoV‐2 clearance
T45 4652-4669 Sentence denotes Richardson et al.
T46 4670-4816 Sentence denotes 8 Case series of hospitalized patients with COVID‐19 in 12 hospitals in the New York City metro area 0.1% (8/5700) of patients were HBV infected
T47 4817-4828 Sentence denotes Guan et al.
T48 4829-4960 Sentence denotes 9 Retrospective multicenter analysis of hospitalized patients with COVID‐19 in China 2.1% (23/1099) of patients were HBV infected
T49 4961-5046 Sentence denotes HBV‐infected individuals represented 2.4% of nonsevere cases and 0.6% of severe cases
T50 5047-5064 Sentence denotes Richardson et al.
T51 5065-5278 Sentence denotes 8 HCV Case series of hospitalized patients with COVID‐19 in 12 hospitals in the New York City metro area <0.1% (3/5700) of patients were HCV infected Low incidence of HCV in hospitalized patients with COVID‐19
T52 5279-5350 Sentence denotes No studies to date have reported the effect of HCV on COVID‐19 outcomes
T53 5351-5468 Sentence denotes Some investigational COVID‐19 medications may be contraindicated in patients with HCV‐related decompensated cirrhosis
T54 5469-5482 Sentence denotes Blanco et al.
T55 5483-5613 Sentence denotes 12 HIV Clinical case series of 5 hospitalized COVID‐19 patients in a single center in Spain 0.92% of patients were HIV infected
T56 5614-5687 Sentence denotes 0 died, 2 were admitted to the ICU (1 remained in the ICU at publication)
T57 5688-5808 Sentence denotes ART regimens adapted to protease inhibitor in all patients Low incidence of hospitalized patients with COVID‐19 and HIV
T58 5809-5835 Sentence denotes ART may need to be adapted
T59 5836-6027 Sentence denotes Although no studies have investigated COVID‐19 in PWIDs, that population has risk factors for severe disease course, including weaker immune system, cardiac pathology, and renal insufficiency
T60 6028-6108 Sentence denotes Heterogeneous data on time to antibody response and time to clinical improvement
T61 6109-6119 Sentence denotes Zhu et al.
T62 6120-6219 Sentence denotes 13 Case study in China in a HIV/SARS‐CoV‐2 co‐infected patient Comorbid diabetes and heavy smoker
T63 6220-6285 Sentence denotes Antibody/antigen test gave positive HIV results (no previous ART)
T64 6286-6297 Sentence denotes Chen et al.
T65 6298-6396 Sentence denotes 15 Case study in China in a patient co‐infected with HIV/SARS‐CoV‐2 Nonsevere COVID‐19 pneumonia
T66 6397-6461 Sentence denotes Had ongoing ART HIV treatment (tenofovir, lamivudine, efavirenz)
T67 6462-6513 Sentence denotes After COVID‐19 diagnosis, given lopinavir/ritonavir
T68 6514-6580 Sentence denotes Shortened disease course and quick resolution of pulmonary lesions
T69 6581-6593 Sentence denotes Aydin et al.
T70 6594-6785 Sentence denotes 14 Case series of 4 patients co‐infected with HIV/SARS‐CoV‐2 in Turkey In limited cases, study highlighted that COVID‐19 infection improved in cases using regular ART with viral suppression
T71 6786-6827 Sentence denotes One patient died of sudden cardiac arrest
T72 6828-6948 Sentence denotes Resolution of radiological findings and time to antibody formation were similar to HIV‐uninfected patients with COVID‐19
T73 6949-6960 Sentence denotes Zhao et al.
T74 6961-7098 Sentence denotes 16 HCV+HIV Case study in China of HIV/HCV co‐infected patient with COVID‐19 Negative SARS‐CoV‐2 RNA test and delayed antibody response
T75 7099-7122 Sentence denotes Was taking anti‐HIV ART
T76 7123-7270 Sentence denotes John Wiley & Sons, Ltd This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response.
T77 7271-7453 Sentence denotes It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
T78 7454-7571 Sentence denotes There have been only sparse reports, involving case series, on the impact of COVID‐19 in patients with HIV infection.
T79 7572-7743 Sentence denotes 12 , 13 , 14 , 15 A Barcelona experience with hospitalized patients with COVID‐19 noted that HIV‐infected individuals accounted for close to only 1% of these patients.
T80 7744-7969 Sentence denotes Those with HIV infection were younger than 50 years, they self‐identified as men who have sex with men, their clinical picture was similar to those who were HIV negative/COVID‐19 positive, and there was no mortality reported.
T81 7970-8342 Sentence denotes 12 There have been only sporadic reports of COVID‐19 in those co‐infected with HIV and HCV, and unique considerations in either HIV mono‐infected or HIV/HCV co‐infected patients would be of adjustments to antiretroviral therapy (ART) based on potential drug‐drug interactions (DDIs); further, antibody response to SARS‐CoV‐2 may be impaired or delayed in this population.
T82 8343-8592 Sentence denotes 16 Thus far, studies have not been presented on the frequency and impact of COVID‐19 in PWIDs, a population vulnerable to the consequences of SARS‐CoV‐2 due to several comorbidities, such as other viral infections, heart disease, and renal disease.
T83 8593-8595 Sentence denotes 17
T84 8596-8839 Sentence denotes Unique considerations in those with HBV and HCV infections involve possible precautions for HBV and HCV therapies in those with or without SARS‐CoV‐2 infection and COVID‐19 manifestations of abnormalities in hepatic biochemical tests (Fig. 1).
T85 8840-9295 Sentence denotes As per the American Association for the Study of Liver Diseases guidance document, it would seem reasonable to initiate HCV therapy, in newly diagnosed cases of HCV, in those without a SARS‐CoV‐2 infection if adequate resources are available and if those resources have not been deployed for COVID‐19 activities (e.g., pharmacy services, personnel for approval of therapy, blood testing service, follow‐up facilities through telemedicine or face‐to‐face).
T86 9296-9538 Sentence denotes 18 In those with COVID‐19 in the background of a recently diagnosed HCV infection, it seems reasonable to defer HCV therapy until a time when COVID‐19 has cleared, whereas already initiated therapy can be continued while monitoring for DDIs.
T87 9539-9725 Sentence denotes In those patients with HBV, it is important to be aware of the risk for HBV reactivation related to medications, such as tocilizumab and corticosteroids, used in the context of COVID‐19.
T88 9726-9886 Sentence denotes Reactivation of HBV following the use of tocilizumab and prednisone has been described, and thus prophylaxis against HBV reactivation should be a consideration.
T89 9887-10078 Sentence denotes 19 , 20 In addition, chronic HBV therapy where indicated as per guidelines 21 can be initiated in those with newly diagnosed HBV and continued if receiving therapy, regardless of COVID‐19.
T90 10079-10447 Sentence denotes Last but not least, caution needs to be exercised in initiating COVID‐19‐related therapy in those with advanced liver disease; thus, established guidelines on such use need to be followed to minimize the risk for hepatic decompensation, although the risk/benefit of an intervention is likely to weigh in heavily in dealing with the highly lethal condition of COVID‐19.
T91 10448-10510 Sentence denotes Fig 1 SARS‐CoV‐2 and COVID‐19: considerations in HBV and HCV.
T92 10511-10575 Sentence denotes COVID‐19 refers to the respiratory illness caused by SARS‐CoV‐2.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 44-53 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T2 60-69 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T3 98-107 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T4 264-273 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T5 286-295 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T6 314-330 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T7 1040-1059 Phenotype denotes acute liver failure http://purl.obolibrary.org/obo/HP_0006554
T8 1423-1439 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T9 1453-1462 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T10 1482-1491 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T11 1632-1646 Phenotype denotes liver diseases http://purl.obolibrary.org/obo/HP_0001392
T12 2056-2069 Phenotype denotes liver disease http://purl.obolibrary.org/obo/HP_0001392
T13 2201-2219 Phenotype denotes chronic infections http://purl.obolibrary.org/obo/HP_0031035
T14 3578-3587 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T15 4386-4395 Phenotype denotes cirrhosis http://purl.obolibrary.org/obo/HP_0001394
T16 5459-5468 Phenotype denotes cirrhosis http://purl.obolibrary.org/obo/HP_0001394
T17 6008-6027 Phenotype denotes renal insufficiency http://purl.obolibrary.org/obo/HP_0000083
T18 6387-6396 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T19 6806-6827 Phenotype denotes sudden cardiac arrest http://purl.obolibrary.org/obo/HP_0031628
T20 8889-8903 Phenotype denotes Liver Diseases http://purl.obolibrary.org/obo/HP_0001392
T21 10191-10204 Phenotype denotes liver disease http://purl.obolibrary.org/obo/HP_0001392
T22 10534-10553 Phenotype denotes respiratory illness http://purl.obolibrary.org/obo/HP_0002086