PMC:7239011
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 3-11 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 27 | 3036-3048 | Gene | denotes | hyposmia5–14 | |
| 28 | 1674-1684 | Species | denotes | Zika virus | Tax:64320 |
| 29 | 3274-3283 | Chemical | denotes | Lopinavir | MESH:D061466 |
| 30 | 1697-1707 | Disease | denotes | COVID SARS | MESH:C000657245 |
| 31 | 2079-2083 | Disease | denotes | pain | MESH:D010146 |
| 32 | 2096-2133 | Disease | denotes | weakness of limbsLess commonAreflexic | MESH:D018908 |
| 33 | 2327-2331 | Disease | denotes | rash | MESH:D005076 |
| 34 | 2333-2340 | Disease | denotes | myalgia | MESH:D063806 |
| 35 | 2369-2377 | Disease | denotes | weakness | MESH:D018908 |
| 36 | 2392-2478 | Disease | denotes | facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonLess | MESH:D005148 |
| 37 | 2643-2651 | Disease | denotes | headache | MESH:D006261 |
| 38 | 2653-2657 | Disease | denotes | rash | MESH:D005076 |
| 39 | 2659-2669 | Disease | denotes | arthralgia | MESH:D018771 |
| 40 | 2671-2679 | Disease | denotes | diarrhea | MESH:D003967 |
| 41 | 2735-2748 | Disease | denotes | limb weakness | MESH:D018908 |
| 42 | 2750-2810 | Disease | denotes | facial weaknessMore commonAreflexic quadri/paraparesisCommon | MESH:D005148 |
| 43 | 3011-3016 | Disease | denotes | cough | MESH:D003371 |
| 44 | 3018-3025 | Disease | denotes | dyspnea | MESH:D004417 |
| 45 | 3027-3034 | Disease | denotes | ageusia | MESH:D000370 |
| 46 | 3072-3085 | Disease | denotes | limb weakness | MESH:D018908 |
| 47 | 3087-3162 | Disease | denotes | facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess | MESH:D005148 |
| 48 | 3196-3209 | Disease | denotes | AIDPPneumonia | |
| 49 | 3224-3246 | Disease | denotes | pneumonitisEnhancement | |
| 50 | 3329-3337 | Disease | denotes | weakness | MESH:D018908 |
| 51 | 3339-3348 | Disease | denotes | dysphagia | MESH:D003680 |
| 54 | 1596-1606 | Species | denotes | Zika virus | Tax:64320 |
| 55 | 1611-1621 | Disease | denotes | COVID SARS | MESH:C000657245 |
| 59 | 3390-3418 | Disease | denotes | demyelinating polyneuropathy | MESH:D003711 |
| 60 | 3433-3456 | Disease | denotes | motor axonal neuropathy | MESH:C536450 |
| 61 | 3472-3503 | Disease | denotes | motor sensory axonal neuropathy | MESH:C536450 |
| 93 | 529-537 | Species | denotes | patients | Tax:9606 |
| 94 | 659-667 | Species | denotes | Patients | Tax:9606 |
| 95 | 1045-1055 | Species | denotes | Zika virus | Tax:64320 |
| 96 | 1090-1098 | Species | denotes | patients | Tax:9606 |
| 97 | 1187-1195 | Species | denotes | patients | Tax:9606 |
| 98 | 1288-1296 | Species | denotes | patients | Tax:9606 |
| 99 | 1441-1449 | Species | denotes | patients | Tax:9606 |
| 100 | 1240-1250 | Chemical | denotes | Gadolinium | MESH:D005682 |
| 101 | 1306-1324 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 102 | 1326-1338 | Chemical | denotes | azithromycin | MESH:D017963 |
| 103 | 1340-1349 | Chemical | denotes | lopinavir | MESH:D061466 |
| 104 | 1354-1363 | Chemical | denotes | ritonavir | MESH:D019438 |
| 105 | 129-150 | Disease | denotes | SARS-Cov-19 infection | MESH:C000657245 |
| 106 | 267-275 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 107 | 276-285 | Disease | denotes | infection | MESH:D007239 |
| 108 | 356-364 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 109 | 407-430 | Disease | denotes | areflexic quadriparesis | MESH:D011782 |
| 110 | 543-551 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 111 | 602-609 | Disease | denotes | ageusia | MESH:D000370 |
| 112 | 614-622 | Disease | denotes | hyposmia | MESH:D000857 |
| 113 | 639-647 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 114 | 648-657 | Disease | denotes | infection | MESH:D007239 |
| 115 | 673-681 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 116 | 720-739 | Disease | denotes | respiratory failure | MESH:D012131 |
| 117 | 753-762 | Disease | denotes | pneumonia | MESH:D011014 |
| 118 | 780-791 | Disease | denotes | pneumonitis | MESH:D011014 |
| 119 | 958-982 | Disease | denotes | demyelinating neuropathy | MESH:D003711 |
| 120 | 1069-1077 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 121 | 1127-1162 | Disease | denotes | axonal motor-sensory polyneuropathy | MESH:D011115 |
| 122 | 1279-1287 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 123 | 1521-1530 | Disease | denotes | dysphagia | MESH:D003680 |
| 136 | 3843-3863 | Species | denotes | Campylobacter jejuni | Tax:197 |
| 137 | 3881-3887 | Species | denotes | jejuni | Tax:197 |
| 138 | 3975-3981 | Species | denotes | jejuni | Tax:197 |
| 139 | 3906-3918 | Chemical | denotes | gangliosides | MESH:D005732 |
| 140 | 4029-4041 | Chemical | denotes | gangliosides | MESH:D005732 |
| 141 | 4070-4073 | Chemical | denotes | GM1 | MESH:D005677 |
| 142 | 4081-4087 | Chemical | denotes | GalNac | |
| 143 | 4133-4144 | Chemical | denotes | ganglioside | MESH:D005732 |
| 144 | 3508-3516 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 145 | 3563-3577 | Disease | denotes | polyneuropathy | MESH:D011115 |
| 146 | 3766-3775 | Disease | denotes | infection | MESH:D007239 |
| 147 | 3957-3966 | Disease | denotes | infection | MESH:D007239 |
| 168 | 4406-4414 | Species | denotes | patients | Tax:9606 |
| 169 | 4420-4432 | Species | denotes | dengue virus | Tax:12637 |
| 170 | 4510-4518 | Species | denotes | patients | Tax:9606 |
| 171 | 4537-4547 | Species | denotes | Zika virus | Tax:64320 |
| 172 | 5054-5062 | Species | denotes | patients | Tax:9606 |
| 173 | 5166-5174 | Species | denotes | patients | Tax:9606 |
| 174 | 5191-5201 | Species | denotes | Zika virus | Tax:64320 |
| 175 | 5289-5297 | Species | denotes | patients | Tax:9606 |
| 176 | 4472-4483 | Chemical | denotes | ganglioside | MESH:D005732 |
| 177 | 4524-4532 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 178 | 4625-4635 | Disease | denotes | neuropathy | MESH:D009422 |
| 179 | 4639-4655 | Disease | denotes | viral infections | MESH:D001102 |
| 180 | 4784-4794 | Disease | denotes | neurotoxic | MESH:D020258 |
| 181 | 4852-4861 | Disease | denotes | infection | MESH:D007239 |
| 182 | 4959-4974 | Disease | denotes | viral infection | MESH:D001102 |
| 183 | 5014-5024 | Disease | denotes | neurotoxic | MESH:D020258 |
| 184 | 5045-5053 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 185 | 5253-5262 | Disease | denotes | pneumonia | MESH:D011014 |
| 186 | 5280-5288 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 187 | 5364-5372 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 832-837 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T2 | 841-846 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T3 | 1225-1236 | Body_part | denotes | nerve roots | http://purl.org/sig/ont/fma/fma5981 |
| T4 | 1225-1230 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
| T5 | 1267-1272 | Body_part | denotes | spine | http://purl.org/sig/ont/fma/fma13478 |
| T6 | 1391-1405 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T7 | 1872-1886 | Body_part | denotes | cranial nerves | http://purl.org/sig/ont/fma/fma63820 |
| T8 | 1949-1954 | Body_part | denotes | Brain | http://purl.org/sig/ont/fma/fma50801 |
| T9 | 2729-2739 | Body_part | denotes | lower limb | http://purl.org/sig/ont/fma/fma7184 |
| T10 | 2868-2881 | Body_part | denotes | cranial nerve | http://purl.org/sig/ont/fma/fma5865 |
| T11 | 3066-3076 | Body_part | denotes | lower limb | http://purl.org/sig/ont/fma/fma7184 |
| T12 | 3257-3262 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
| T13 | 3645-3661 | Body_part | denotes | peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
| T14 | 3713-3725 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T15 | 3713-3717 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T16 | 3906-3918 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T17 | 3993-4001 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T18 | 4029-4041 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T19 | 4133-4144 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T20 | 4301-4317 | Body_part | denotes | peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
| T21 | 4318-4329 | Body_part | denotes | glycolipids | http://purl.org/sig/ont/fma/fma82780 |
| T22 | 4375-4383 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T23 | 4472-4483 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T24 | 4484-4492 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T25 | 4758-4763 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
| T26 | 4865-4882 | Body_part | denotes | peripheral nerves | http://purl.org/sig/ont/fma/fma65239 |
| T27 | 5303-5309 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T28 | 5324-5330 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T29 | 5611-5619 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T30 | 5789-5797 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 841-846 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T2 | 1225-1236 | Body_part | denotes | nerve roots | http://purl.obolibrary.org/obo/UBERON_0002211 |
| T3 | 1225-1230 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T4 | 1872-1886 | Body_part | denotes | cranial nerves | http://purl.obolibrary.org/obo/UBERON_0001785 |
| T5 | 1949-1954 | Body_part | denotes | Brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T6 | 2735-2739 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
| T7 | 2868-2881 | Body_part | denotes | cranial nerve | http://purl.obolibrary.org/obo/UBERON_0001785 |
| T8 | 2876-2881 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T9 | 3072-3076 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
| T10 | 3257-3262 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T11 | 3656-3661 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T12 | 4312-4317 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T13 | 4758-4763 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 417-430 | Phenotype | denotes | quadriparesis | http://purl.obolibrary.org/obo/HP_0002273 |
| T2 | 602-609 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
| T3 | 614-622 | Phenotype | denotes | hyposmia | http://purl.obolibrary.org/obo/HP_0004409 |
| T4 | 720-739 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T5 | 753-762 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T6 | 767-791 | Phenotype | denotes | interstitial pneumonitis | http://purl.obolibrary.org/obo/HP_0006515 |
| T7 | 958-971 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
| T8 | 972-982 | Phenotype | denotes | neuropathy | http://purl.obolibrary.org/obo/HP_0009830 |
| T9 | 1148-1162 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
| T10 | 1521-1530 | Phenotype | denotes | dysphagia | http://purl.obolibrary.org/obo/HP_0002015 |
| T11 | 2079-2083 | Phenotype | denotes | pain | http://purl.obolibrary.org/obo/HP_0012531 |
| T12 | 2327-2331 | Phenotype | denotes | rash | http://purl.obolibrary.org/obo/HP_0000988 |
| T13 | 2333-2340 | Phenotype | denotes | myalgia | http://purl.obolibrary.org/obo/HP_0003326 |
| T14 | 2379-2390 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T15 | 2643-2651 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
| T16 | 2653-2657 | Phenotype | denotes | rash | http://purl.obolibrary.org/obo/HP_0000988 |
| T17 | 2659-2669 | Phenotype | denotes | arthralgia | http://purl.obolibrary.org/obo/HP_0002829 |
| T18 | 2671-2679 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
| T19 | 2716-2727 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T20 | 2729-2748 | Phenotype | denotes | lower limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
| T21 | 3011-3016 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T22 | 3018-3025 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
| T23 | 3027-3034 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
| T24 | 3066-3085 | Phenotype | denotes | lower limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
| T25 | 3339-3348 | Phenotype | denotes | dysphagia | http://purl.obolibrary.org/obo/HP_0002015 |
| T26 | 3390-3403 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
| T27 | 3404-3418 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
| T28 | 3433-3456 | Phenotype | denotes | motor axonal neuropathy | http://purl.obolibrary.org/obo/HP_0007002 |
| T29 | 3478-3503 | Phenotype | denotes | sensory axonal neuropathy | http://purl.obolibrary.org/obo/HP_0003390 |
| T30 | 3563-3577 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
| T31 | 4625-4635 | Phenotype | denotes | neuropathy | http://purl.obolibrary.org/obo/HP_0009830 |
| T32 | 5253-5262 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 3-11 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 20-43 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T3 | 92-115 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T4 | 129-133 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 141-150 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T6 | 217-240 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T7 | 242-245 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T8 | 267-275 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 276-285 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T10 | 356-364 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 373-376 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T12 | 543-551 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T13 | 560-563 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T14 | 639-647 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T15 | 648-657 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T16 | 673-681 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T17 | 690-693 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T18 | 720-739 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T19 | 753-762 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T20 | 780-791 | Disease | denotes | pneumonitis | http://purl.obolibrary.org/obo/MONDO_0043905 |
| T21 | 972-982 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T22 | 1011-1014 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T23 | 1019-1022 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T24 | 1034-1040 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T25 | 1045-1049 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T26 | 1069-1077 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T27 | 1086-1089 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T28 | 1117-1121 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T29 | 1148-1162 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
| T30 | 1164-1169 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T31 | 1279-1287 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T32 | 1583-1586 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T33 | 1588-1594 | Disease | denotes | Dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T34 | 1596-1600 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T35 | 1617-1621 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T36 | 1630-1633 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T37 | 1651-1654 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T38 | 1655-1661 | Disease | denotes | Dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T39 | 1670-1673 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T40 | 1674-1678 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T41 | 1693-1696 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T42 | 1703-1707 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T43 | 1716-1719 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T44 | 2525-2530 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T45 | 2671-2679 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T46 | 2883-2887 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
| T47 | 2890-2894 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T48 | 2896-2901 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T49 | 3183-3188 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T50 | 3190-3194 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T51 | 3364-3368 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
| T52 | 3371-3418 | Disease | denotes | Acute inflammatory demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T53 | 3390-3418 | Disease | denotes | demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0003334 |
| T54 | 3404-3418 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
| T55 | 3420-3424 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T56 | 3427-3456 | Disease | denotes | Acute motor axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T57 | 3439-3456 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
| T58 | 3446-3456 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T59 | 3458-3463 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T60 | 3466-3503 | Disease | denotes | Acute motor sensory axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T61 | 3486-3503 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
| T62 | 3493-3503 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T63 | 3508-3516 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T64 | 3525-3528 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T65 | 3563-3577 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
| T66 | 3581-3584 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T67 | 3766-3775 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T68 | 3873-3876 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T69 | 3957-3966 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T70 | 4184-4188 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T71 | 4190-4195 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T72 | 4215-4230 | Disease | denotes | variants of GBS | http://purl.obolibrary.org/obo/MONDO_0016493 |
| T73 | 4227-4230 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T74 | 4420-4426 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T75 | 4441-4444 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T76 | 4524-4532 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T77 | 4537-4541 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T78 | 4556-4559 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T79 | 4625-4635 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T80 | 4639-4655 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T81 | 4664-4667 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T82 | 4852-4861 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T83 | 4959-4974 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T84 | 4965-4974 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T85 | 4983-4986 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T86 | 5045-5053 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T87 | 5068-5072 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
| T88 | 5123-5138 | Disease | denotes | variants of GBS | http://purl.obolibrary.org/obo/MONDO_0016493 |
| T89 | 5135-5138 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T90 | 5180-5186 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T91 | 5191-5195 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T92 | 5210-5213 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T93 | 5253-5262 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T94 | 5280-5288 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T95 | 5364-5372 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T96 | 5381-5384 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 517-521 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T2 | 698-699 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 832-837 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T4 | 841-846 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T5 | 1050-1055 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T6 | 1172-1173 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T7 | 1225-1230 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T8 | 1601-1606 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T9 | 1679-1684 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T10 | 1880-1886 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
| T11 | 1949-1954 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | Brain |
| T12 | 1949-1954 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | Brain |
| T13 | 2735-2739 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T14 | 2876-2881 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T15 | 3072-3076 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T16 | 3257-3262 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T17 | 3529-3532 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T18 | 3533-3534 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T19 | 3645-3661 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | peripheral nerve |
| T20 | 3713-3717 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T21 | 3729-3737 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
| T22 | 4060-4068 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T23 | 4301-4317 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | peripheral nerve |
| T24 | 4400-4401 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T25 | 4427-4432 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T26 | 4542-4547 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T27 | 4593-4596 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T28 | 4741-4748 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T29 | 4758-4763 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T30 | 4876-4882 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
| T31 | 4886-4893 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T32 | 5036-5043 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T33 | 5140-5141 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T34 | 5196-5201 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T35 | 5225-5226 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T36 | 5263-5266 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T37 | 5303-5309 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T38 | 5324-5330 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T39 | 5620-5621 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T40 | 5798-5799 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 1306-1324 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T2 | 1326-1338 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T3 | 1340-1363 | Chemical | denotes | lopinavir and ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
| T4 | 1340-1349 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T5 | 1354-1363 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T6 | 3274-3283 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T7 | 3285-3294 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T8 | 3906-3918 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T9 | 3919-3926 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T10 | 4029-4041 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T11 | 4070-4073 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
| T14 | 4075-4079 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
| T16 | 4088-4092 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
| T18 | 4094-4098 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
| T19 | 4103-4107 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T20 | 4133-4144 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T21 | 4288-4296 | Chemical | denotes | antigens | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T22 | 4318-4329 | Chemical | denotes | glycolipids | http://purl.obolibrary.org/obo/CHEBI_33563 |
| T23 | 4370-4374 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
| T25 | 4472-4483 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 3545-3557 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
| T2 | 4002-4011 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T3 | 4639-4655 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
| T4 | 4959-4974 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-54 | Sentence | denotes | Is COVID-19-related Guillain-Barré syndrome different? |
| T2 | 56-163 | Sentence | denotes | We read with interest the report of Guillain-Barré syndrome secondary to SARS-Cov-19 infection (Coen et al. |
| T3 | 164-170 | Sentence | denotes | 2020). |
| T4 | 171-350 | Sentence | denotes | Recently, there have been multiple reports of Guillain-Barré syndrome (GBS) associated with the COVID-19 infection (Sedaghat and Karimi, 2020, Toscano et al.,, Zhao et al., 2020). |
| T5 | 351-431 | Sentence | denotes | Most COVID-19-related GBS presented with acute onset of areflexic quadriparesis. |
| T6 | 432-523 | Sentence | denotes | However, there are some important differences to highlight (table 1 ). (Garg et al., 2018). |
| T7 | 524-577 | Sentence | denotes | Most patients with COVID-19-related GBS were elderly. |
| T8 | 578-658 | Sentence | denotes | Preceding symptoms like ageusia and hyposmia were unique for COVID-19 infection. |
| T9 | 659-792 | Sentence | denotes | Patients with COVID-19-related GBS had a severe disease with respiratory failure due to lobar pneumonia and interstitial pneumonitis. |
| T10 | 793-871 | Sentence | denotes | They showed ground-glass appearance of lungs on chest computerized tomography. |
| T11 | 872-951 | Sentence | denotes | Increased severity of disease is also evident from the electrophysiology study. |
| T12 | 952-1171 | Sentence | denotes | Where demyelinating neuropathy is more common with typical GBS and GBS related to dengue and Zika virus, majority of COVID-19-related GBS patients had axonal motor (AMAN) and axonal motor-sensory polyneuropathy (AMSAN). |
| T13 | 1172-1273 | Sentence | denotes | A few of these patients showed enhancement of caudal nerve roots on Gadolinium-enhanced MRI of spine. |
| T14 | 1274-1413 | Sentence | denotes | Most COVID-19 patients received hydroxychloroquine, azithromycin, lopinavir and ritonavir in addition to intravenous immunoglobulin (IVIG). |
| T15 | 1414-1531 | Sentence | denotes | However, more than half of patients showed poor outcome in the form of long ICU stay, residual paresis and dysphagia. |
| T16 | 1532-1634 | Sentence | denotes | Table 1 Differences in the presentation of Typical GBS, Dengue, Zika virus and COVID SARS related GBS. |
| T17 | 1635-1719 | Sentence | denotes | Feature Typical GBS Dengue-related GBS Zika virus-related GBS COVID SARS related GBS |
| T18 | 1720-3363 | Sentence | denotes | Geographical distributionAgeSexPreceding illnessMean time to GBSInitial symptomsDysphagiaSignsFacial diplegiaDysautonomiaAtaxiaRespiratory failureOther cranial nerves involvedLeukopeniaThrombocytopeniaNerve conductionCT chestMRI Brain/spineTreatmentOutcome GlobalAll age groupsMales 1.5 times more affectedRespiratory or gastrointestinal< 6 weeksParesthesia, pain followed by weakness of limbsLess commonAreflexic quadreparesisCommonCommonLess common25%Ocular nervesUncommonUncommonAIDP--IVIG, PlasmapherisisGood, persistent disability in 20%-30% Latin America, IndiaAll age groupsMales:Females EqualFever, rash, myalgia, headache1–30 daysAscending weakness, paresthesia, facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonLess commonGlossopharyngeal nerveCommonCommonAIDP, AMSAN--IVIG, PlasmapheresisGood Latin America, Europe, East Asia, North AmericalMiddle age to elderlyMore malesFever, headache, rash, arthralgia, diarrhea, conjunctivitis0–10 daysLimb pains, paresthesia, lower limb weakness, facial weaknessMore commonAreflexic quadri/paraparesisCommon (>50%)Common (up to 30%)Common (up to 70%)Less common3rd cranial nerve--AIDP > AMAN, AMSAN--IVIG, PlasmapheresisGood, half may require ICU care China, Iran, Europe, USAUsually elderlyMore malesFever, cough, dyspnea, ageusia, hyposmia5–14 daysParesthesia, lower limb weakness, facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonCommon-Common-AMSAN, AMAN, AIDPPneumonia, interstitial pneumonitisEnhancement of caudal nerve rootsIVIG, Lopinavir, ritonavir, HCQ, Azithromycin,Poor, residual weakness, dysphagia, long ICU stay |
| T19 | 3364-3504 | Sentence | denotes | AIDP – Acute inflammatory demyelinating polyneuropathy, AMAN – Acute motor axonal neuropathy, AMSAN – Acute motor sensory axonal neuropathy. |
| T20 | 3505-3558 | Sentence | denotes | Is COVID-19-related GBS has a different pathogenesis? |
| T21 | 3559-3776 | Sentence | denotes | The polyneuropathy in GBS is believed to be due to cross-immunity against epitopes of peripheral nerve components that it shares with the epitopes on the cell surface of bacteria that produces an antecedent infection. |
| T22 | 3777-3877 | Sentence | denotes | This mechanism of “molecular mimicry” is best understood with the Campylobacter jejuni -related GBS. |
| T23 | 3878-3945 | Sentence | denotes | C. jejuni expresses various gangliosides antigen on its outer core. |
| T24 | 3946-4109 | Sentence | denotes | Antecedent infection with C. jejuni results in antibody formation against specific gangliosides present on axonal membrane (GM1, GD1a, GalNac-GD1a, GD1b and GQ1b). |
| T25 | 4110-4254 | Sentence | denotes | Presence of these anti-ganglioside antibodies is strongly associated with AMAN, AMSAN and Miller-Fischer variants of GBS (Ogawara et al., 2000). |
| T26 | 4255-4360 | Sentence | denotes | The cross-immunity between viral antigens and peripheral nerve glycolipids have not been well-documented. |
| T27 | 4361-4466 | Sentence | denotes | Positive GD1a antibody was reported in a few patients with dengue virus-related GBS (Simon et al., 2016). |
| T28 | 4467-4587 | Sentence | denotes | Anti-ganglioside antibody was not found in patients with COVID-19 and Zika virus-related GBS (Cao-Lormeau et al., 2016). |
| T29 | 4588-4803 | Sentence | denotes | This has led to speculation that the neuropathy in viral infections-related GBS could be due to other autoantibodies that are not detected as yet or the viruses produced nerve damage due to other neurotoxic effects. |
| T30 | 4804-4924 | Sentence | denotes | However, there is paucity of evidence of direct infection of peripheral nerves by viruses from the pathological studies. |
| T31 | 4925-5044 | Sentence | denotes | Good response to immunotherapy in viral infection-related GBS is also against the direct neurotoxic effects of viruses. |
| T32 | 5045-5214 | Sentence | denotes | COVID-19 patients with AIDP responded better as compared to those with axonal variants of GBS; a difference also seen in patients with dengue and Zika virus-related GBS. |
| T33 | 5215-5318 | Sentence | denotes | Recently, a good clinical response in pneumonia has been seen in COVID-19 patients with plasma therapy. |
| T34 | 5319-5403 | Sentence | denotes | Does plasma therapy produce good recovery in COVID-19-related GBS is yet to be seen. |
| T35 | 5405-5438 | Sentence | denotes | Declaration of Competing Interest |
| T36 | 5439-5609 | Sentence | denotes | The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| T37 | 5611-5641 | Sentence | denotes | Appendix A Supplementary data |
| T38 | 5642-5719 | Sentence | denotes | The following are the Supplementary data to this article:Supplementary data 1 |
| T39 | 5721-5736 | Sentence | denotes | Acknowledgement |
| T40 | 5737-5742 | Sentence | denotes | None. |
| T41 | 5743-5750 | Sentence | denotes | Funding |
| T42 | 5751-5788 | Sentence | denotes | The work did not receive any funding. |
| T43 | 5789-5901 | Sentence | denotes | Appendix A Supplementary data to this article can be found online at https://doi.org/10.1016/j.bbi.2020.05.051. |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 4070-4073 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 4075-4079 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |
| T3 | 4081-4092 | GlycoEpitope | denotes | GalNac-GD1a | http://www.glycoepitope.jp/epitopes/EP0058 |
| T4 | 4088-4092 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |
| T5 | 4094-4098 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T6 | 4103-4107 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T7 | 4370-4374 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |