PMC:7239011
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1 | 3-11 | Disease | denotes | COVID-19 | MESH:C000657245 |
27 | 3036-3048 | Gene | denotes | hyposmia5–14 | |
28 | 1674-1684 | Species | denotes | Zika virus | Tax:64320 |
29 | 3274-3283 | Chemical | denotes | Lopinavir | MESH:D061466 |
30 | 1697-1707 | Disease | denotes | COVID SARS | MESH:C000657245 |
31 | 2079-2083 | Disease | denotes | pain | MESH:D010146 |
32 | 2096-2133 | Disease | denotes | weakness of limbsLess commonAreflexic | MESH:D018908 |
33 | 2327-2331 | Disease | denotes | rash | MESH:D005076 |
34 | 2333-2340 | Disease | denotes | myalgia | MESH:D063806 |
35 | 2369-2377 | Disease | denotes | weakness | MESH:D018908 |
36 | 2392-2478 | Disease | denotes | facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonLess | MESH:D005148 |
37 | 2643-2651 | Disease | denotes | headache | MESH:D006261 |
38 | 2653-2657 | Disease | denotes | rash | MESH:D005076 |
39 | 2659-2669 | Disease | denotes | arthralgia | MESH:D018771 |
40 | 2671-2679 | Disease | denotes | diarrhea | MESH:D003967 |
41 | 2735-2748 | Disease | denotes | limb weakness | MESH:D018908 |
42 | 2750-2810 | Disease | denotes | facial weaknessMore commonAreflexic quadri/paraparesisCommon | MESH:D005148 |
43 | 3011-3016 | Disease | denotes | cough | MESH:D003371 |
44 | 3018-3025 | Disease | denotes | dyspnea | MESH:D004417 |
45 | 3027-3034 | Disease | denotes | ageusia | MESH:D000370 |
46 | 3072-3085 | Disease | denotes | limb weakness | MESH:D018908 |
47 | 3087-3162 | Disease | denotes | facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess | MESH:D005148 |
48 | 3196-3209 | Disease | denotes | AIDPPneumonia | |
49 | 3224-3246 | Disease | denotes | pneumonitisEnhancement | |
50 | 3329-3337 | Disease | denotes | weakness | MESH:D018908 |
51 | 3339-3348 | Disease | denotes | dysphagia | MESH:D003680 |
54 | 1596-1606 | Species | denotes | Zika virus | Tax:64320 |
55 | 1611-1621 | Disease | denotes | COVID SARS | MESH:C000657245 |
59 | 3390-3418 | Disease | denotes | demyelinating polyneuropathy | MESH:D003711 |
60 | 3433-3456 | Disease | denotes | motor axonal neuropathy | MESH:C536450 |
61 | 3472-3503 | Disease | denotes | motor sensory axonal neuropathy | MESH:C536450 |
93 | 529-537 | Species | denotes | patients | Tax:9606 |
94 | 659-667 | Species | denotes | Patients | Tax:9606 |
95 | 1045-1055 | Species | denotes | Zika virus | Tax:64320 |
96 | 1090-1098 | Species | denotes | patients | Tax:9606 |
97 | 1187-1195 | Species | denotes | patients | Tax:9606 |
98 | 1288-1296 | Species | denotes | patients | Tax:9606 |
99 | 1441-1449 | Species | denotes | patients | Tax:9606 |
100 | 1240-1250 | Chemical | denotes | Gadolinium | MESH:D005682 |
101 | 1306-1324 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
102 | 1326-1338 | Chemical | denotes | azithromycin | MESH:D017963 |
103 | 1340-1349 | Chemical | denotes | lopinavir | MESH:D061466 |
104 | 1354-1363 | Chemical | denotes | ritonavir | MESH:D019438 |
105 | 129-150 | Disease | denotes | SARS-Cov-19 infection | MESH:C000657245 |
106 | 267-275 | Disease | denotes | COVID-19 | MESH:C000657245 |
107 | 276-285 | Disease | denotes | infection | MESH:D007239 |
108 | 356-364 | Disease | denotes | COVID-19 | MESH:C000657245 |
109 | 407-430 | Disease | denotes | areflexic quadriparesis | MESH:D011782 |
110 | 543-551 | Disease | denotes | COVID-19 | MESH:C000657245 |
111 | 602-609 | Disease | denotes | ageusia | MESH:D000370 |
112 | 614-622 | Disease | denotes | hyposmia | MESH:D000857 |
113 | 639-647 | Disease | denotes | COVID-19 | MESH:C000657245 |
114 | 648-657 | Disease | denotes | infection | MESH:D007239 |
115 | 673-681 | Disease | denotes | COVID-19 | MESH:C000657245 |
116 | 720-739 | Disease | denotes | respiratory failure | MESH:D012131 |
117 | 753-762 | Disease | denotes | pneumonia | MESH:D011014 |
118 | 780-791 | Disease | denotes | pneumonitis | MESH:D011014 |
119 | 958-982 | Disease | denotes | demyelinating neuropathy | MESH:D003711 |
120 | 1069-1077 | Disease | denotes | COVID-19 | MESH:C000657245 |
121 | 1127-1162 | Disease | denotes | axonal motor-sensory polyneuropathy | MESH:D011115 |
122 | 1279-1287 | Disease | denotes | COVID-19 | MESH:C000657245 |
123 | 1521-1530 | Disease | denotes | dysphagia | MESH:D003680 |
136 | 3843-3863 | Species | denotes | Campylobacter jejuni | Tax:197 |
137 | 3881-3887 | Species | denotes | jejuni | Tax:197 |
138 | 3975-3981 | Species | denotes | jejuni | Tax:197 |
139 | 3906-3918 | Chemical | denotes | gangliosides | MESH:D005732 |
140 | 4029-4041 | Chemical | denotes | gangliosides | MESH:D005732 |
141 | 4070-4073 | Chemical | denotes | GM1 | MESH:D005677 |
142 | 4081-4087 | Chemical | denotes | GalNac | |
143 | 4133-4144 | Chemical | denotes | ganglioside | MESH:D005732 |
144 | 3508-3516 | Disease | denotes | COVID-19 | MESH:C000657245 |
145 | 3563-3577 | Disease | denotes | polyneuropathy | MESH:D011115 |
146 | 3766-3775 | Disease | denotes | infection | MESH:D007239 |
147 | 3957-3966 | Disease | denotes | infection | MESH:D007239 |
168 | 4406-4414 | Species | denotes | patients | Tax:9606 |
169 | 4420-4432 | Species | denotes | dengue virus | Tax:12637 |
170 | 4510-4518 | Species | denotes | patients | Tax:9606 |
171 | 4537-4547 | Species | denotes | Zika virus | Tax:64320 |
172 | 5054-5062 | Species | denotes | patients | Tax:9606 |
173 | 5166-5174 | Species | denotes | patients | Tax:9606 |
174 | 5191-5201 | Species | denotes | Zika virus | Tax:64320 |
175 | 5289-5297 | Species | denotes | patients | Tax:9606 |
176 | 4472-4483 | Chemical | denotes | ganglioside | MESH:D005732 |
177 | 4524-4532 | Disease | denotes | COVID-19 | MESH:C000657245 |
178 | 4625-4635 | Disease | denotes | neuropathy | MESH:D009422 |
179 | 4639-4655 | Disease | denotes | viral infections | MESH:D001102 |
180 | 4784-4794 | Disease | denotes | neurotoxic | MESH:D020258 |
181 | 4852-4861 | Disease | denotes | infection | MESH:D007239 |
182 | 4959-4974 | Disease | denotes | viral infection | MESH:D001102 |
183 | 5014-5024 | Disease | denotes | neurotoxic | MESH:D020258 |
184 | 5045-5053 | Disease | denotes | COVID-19 | MESH:C000657245 |
185 | 5253-5262 | Disease | denotes | pneumonia | MESH:D011014 |
186 | 5280-5288 | Disease | denotes | COVID-19 | MESH:C000657245 |
187 | 5364-5372 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 832-837 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T2 | 841-846 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T3 | 1225-1236 | Body_part | denotes | nerve roots | http://purl.org/sig/ont/fma/fma5981 |
T4 | 1225-1230 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
T5 | 1267-1272 | Body_part | denotes | spine | http://purl.org/sig/ont/fma/fma13478 |
T6 | 1391-1405 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T7 | 1872-1886 | Body_part | denotes | cranial nerves | http://purl.org/sig/ont/fma/fma63820 |
T8 | 1949-1954 | Body_part | denotes | Brain | http://purl.org/sig/ont/fma/fma50801 |
T9 | 2729-2739 | Body_part | denotes | lower limb | http://purl.org/sig/ont/fma/fma7184 |
T10 | 2868-2881 | Body_part | denotes | cranial nerve | http://purl.org/sig/ont/fma/fma5865 |
T11 | 3066-3076 | Body_part | denotes | lower limb | http://purl.org/sig/ont/fma/fma7184 |
T12 | 3257-3262 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
T13 | 3645-3661 | Body_part | denotes | peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
T14 | 3713-3725 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T15 | 3713-3717 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T16 | 3906-3918 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
T17 | 3993-4001 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T18 | 4029-4041 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
T19 | 4133-4144 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
T20 | 4301-4317 | Body_part | denotes | peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
T21 | 4318-4329 | Body_part | denotes | glycolipids | http://purl.org/sig/ont/fma/fma82780 |
T22 | 4375-4383 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T23 | 4472-4483 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
T24 | 4484-4492 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T25 | 4758-4763 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
T26 | 4865-4882 | Body_part | denotes | peripheral nerves | http://purl.org/sig/ont/fma/fma65239 |
T27 | 5303-5309 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
T28 | 5324-5330 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
T29 | 5611-5619 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
T30 | 5789-5797 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 841-846 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T2 | 1225-1236 | Body_part | denotes | nerve roots | http://purl.obolibrary.org/obo/UBERON_0002211 |
T3 | 1225-1230 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T4 | 1872-1886 | Body_part | denotes | cranial nerves | http://purl.obolibrary.org/obo/UBERON_0001785 |
T5 | 1949-1954 | Body_part | denotes | Brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
T6 | 2735-2739 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
T7 | 2868-2881 | Body_part | denotes | cranial nerve | http://purl.obolibrary.org/obo/UBERON_0001785 |
T8 | 2876-2881 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T9 | 3072-3076 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
T10 | 3257-3262 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T11 | 3656-3661 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T12 | 4312-4317 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T13 | 4758-4763 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 417-430 | Phenotype | denotes | quadriparesis | http://purl.obolibrary.org/obo/HP_0002273 |
T2 | 602-609 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
T3 | 614-622 | Phenotype | denotes | hyposmia | http://purl.obolibrary.org/obo/HP_0004409 |
T4 | 720-739 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
T5 | 753-762 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T6 | 767-791 | Phenotype | denotes | interstitial pneumonitis | http://purl.obolibrary.org/obo/HP_0006515 |
T7 | 958-971 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
T8 | 972-982 | Phenotype | denotes | neuropathy | http://purl.obolibrary.org/obo/HP_0009830 |
T9 | 1148-1162 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
T10 | 1521-1530 | Phenotype | denotes | dysphagia | http://purl.obolibrary.org/obo/HP_0002015 |
T11 | 2079-2083 | Phenotype | denotes | pain | http://purl.obolibrary.org/obo/HP_0012531 |
T12 | 2327-2331 | Phenotype | denotes | rash | http://purl.obolibrary.org/obo/HP_0000988 |
T13 | 2333-2340 | Phenotype | denotes | myalgia | http://purl.obolibrary.org/obo/HP_0003326 |
T14 | 2379-2390 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
T15 | 2643-2651 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
T16 | 2653-2657 | Phenotype | denotes | rash | http://purl.obolibrary.org/obo/HP_0000988 |
T17 | 2659-2669 | Phenotype | denotes | arthralgia | http://purl.obolibrary.org/obo/HP_0002829 |
T18 | 2671-2679 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T19 | 2716-2727 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
T20 | 2729-2748 | Phenotype | denotes | lower limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
T21 | 3011-3016 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
T22 | 3018-3025 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
T23 | 3027-3034 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
T24 | 3066-3085 | Phenotype | denotes | lower limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
T25 | 3339-3348 | Phenotype | denotes | dysphagia | http://purl.obolibrary.org/obo/HP_0002015 |
T26 | 3390-3403 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
T27 | 3404-3418 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
T28 | 3433-3456 | Phenotype | denotes | motor axonal neuropathy | http://purl.obolibrary.org/obo/HP_0007002 |
T29 | 3478-3503 | Phenotype | denotes | sensory axonal neuropathy | http://purl.obolibrary.org/obo/HP_0003390 |
T30 | 3563-3577 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
T31 | 4625-4635 | Phenotype | denotes | neuropathy | http://purl.obolibrary.org/obo/HP_0009830 |
T32 | 5253-5262 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 3-11 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 20-43 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
T3 | 92-115 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
T4 | 129-133 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T5 | 141-150 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T6 | 217-240 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
T7 | 242-245 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T8 | 267-275 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T9 | 276-285 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T10 | 356-364 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T11 | 373-376 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T12 | 543-551 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 560-563 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T14 | 639-647 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T15 | 648-657 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T16 | 673-681 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 690-693 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T18 | 720-739 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
T19 | 753-762 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T20 | 780-791 | Disease | denotes | pneumonitis | http://purl.obolibrary.org/obo/MONDO_0043905 |
T21 | 972-982 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
T22 | 1011-1014 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T23 | 1019-1022 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T24 | 1034-1040 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
T25 | 1045-1049 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
T26 | 1069-1077 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T27 | 1086-1089 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T28 | 1117-1121 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
T29 | 1148-1162 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
T30 | 1164-1169 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T31 | 1279-1287 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T32 | 1583-1586 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T33 | 1588-1594 | Disease | denotes | Dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
T34 | 1596-1600 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
T35 | 1617-1621 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T36 | 1630-1633 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T37 | 1651-1654 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T38 | 1655-1661 | Disease | denotes | Dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
T39 | 1670-1673 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T40 | 1674-1678 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
T41 | 1693-1696 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T42 | 1703-1707 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T43 | 1716-1719 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T44 | 2525-2530 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T45 | 2671-2679 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T46 | 2883-2887 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
T47 | 2890-2894 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
T48 | 2896-2901 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T49 | 3183-3188 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T50 | 3190-3194 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
T51 | 3364-3368 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
T52 | 3371-3418 | Disease | denotes | Acute inflammatory demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0016218 |
T53 | 3390-3418 | Disease | denotes | demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0003334 |
T54 | 3404-3418 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
T55 | 3420-3424 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
T56 | 3427-3456 | Disease | denotes | Acute motor axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020349 |
T57 | 3439-3456 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
T58 | 3446-3456 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
T59 | 3458-3463 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T60 | 3466-3503 | Disease | denotes | Acute motor sensory axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020348 |
T61 | 3486-3503 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
T62 | 3493-3503 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
T63 | 3508-3516 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T64 | 3525-3528 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T65 | 3563-3577 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
T66 | 3581-3584 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T67 | 3766-3775 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T68 | 3873-3876 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T69 | 3957-3966 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T70 | 4184-4188 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
T71 | 4190-4195 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
T72 | 4215-4230 | Disease | denotes | variants of GBS | http://purl.obolibrary.org/obo/MONDO_0016493 |
T73 | 4227-4230 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T74 | 4420-4426 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
T75 | 4441-4444 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T76 | 4524-4532 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T77 | 4537-4541 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
T78 | 4556-4559 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T79 | 4625-4635 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
T80 | 4639-4655 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
T81 | 4664-4667 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T82 | 4852-4861 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T83 | 4959-4974 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
T84 | 4965-4974 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T85 | 4983-4986 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T86 | 5045-5053 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T87 | 5068-5072 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
T88 | 5123-5138 | Disease | denotes | variants of GBS | http://purl.obolibrary.org/obo/MONDO_0016493 |
T89 | 5135-5138 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T90 | 5180-5186 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
T91 | 5191-5195 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
T92 | 5210-5213 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T93 | 5253-5262 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T94 | 5280-5288 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T95 | 5364-5372 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T96 | 5381-5384 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 517-521 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
T2 | 698-699 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T3 | 832-837 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T4 | 841-846 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T5 | 1050-1055 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T6 | 1172-1173 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T7 | 1225-1230 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T8 | 1601-1606 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T9 | 1679-1684 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T10 | 1880-1886 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
T11 | 1949-1954 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | Brain |
T12 | 1949-1954 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | Brain |
T13 | 2735-2739 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
T14 | 2876-2881 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T15 | 3072-3076 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
T16 | 3257-3262 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T17 | 3529-3532 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T18 | 3533-3534 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T19 | 3645-3661 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | peripheral nerve |
T20 | 3713-3717 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T21 | 3729-3737 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T22 | 4060-4068 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T23 | 4301-4317 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | peripheral nerve |
T24 | 4400-4401 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T25 | 4427-4432 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T26 | 4542-4547 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T27 | 4593-4596 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T28 | 4741-4748 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T29 | 4758-4763 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T30 | 4876-4882 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
T31 | 4886-4893 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T32 | 5036-5043 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T33 | 5140-5141 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T34 | 5196-5201 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T35 | 5225-5226 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T36 | 5263-5266 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T37 | 5303-5309 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T38 | 5324-5330 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T39 | 5620-5621 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T40 | 5798-5799 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 1306-1324 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T2 | 1326-1338 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
T3 | 1340-1363 | Chemical | denotes | lopinavir and ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T4 | 1340-1349 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T5 | 1354-1363 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T6 | 3274-3283 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T7 | 3285-3294 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T8 | 3906-3918 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
T9 | 3919-3926 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
T10 | 4029-4041 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
T11 | 4070-4073 | Chemical | denotes | GM1 | http://purl.obolibrary.org/obo/CHEBI_18216|http://purl.obolibrary.org/obo/CHEBI_61048|http://purl.obolibrary.org/obo/CHEBI_73110 |
T14 | 4075-4079 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
T16 | 4088-4092 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
T18 | 4094-4098 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
T19 | 4103-4107 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
T20 | 4133-4144 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
T21 | 4288-4296 | Chemical | denotes | antigens | http://purl.obolibrary.org/obo/CHEBI_59132 |
T22 | 4318-4329 | Chemical | denotes | glycolipids | http://purl.obolibrary.org/obo/CHEBI_33563 |
T23 | 4370-4374 | Chemical | denotes | GD1a | http://purl.obolibrary.org/obo/CHEBI_18163|http://purl.obolibrary.org/obo/CHEBI_82607 |
T25 | 4472-4483 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 3545-3557 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
T2 | 4002-4011 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
T3 | 4639-4655 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
T4 | 4959-4974 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-54 | Sentence | denotes | Is COVID-19-related Guillain-Barré syndrome different? |
T2 | 56-163 | Sentence | denotes | We read with interest the report of Guillain-Barré syndrome secondary to SARS-Cov-19 infection (Coen et al. |
T3 | 164-170 | Sentence | denotes | 2020). |
T4 | 171-350 | Sentence | denotes | Recently, there have been multiple reports of Guillain-Barré syndrome (GBS) associated with the COVID-19 infection (Sedaghat and Karimi, 2020, Toscano et al.,, Zhao et al., 2020). |
T5 | 351-431 | Sentence | denotes | Most COVID-19-related GBS presented with acute onset of areflexic quadriparesis. |
T6 | 432-523 | Sentence | denotes | However, there are some important differences to highlight (table 1 ). (Garg et al., 2018). |
T7 | 524-577 | Sentence | denotes | Most patients with COVID-19-related GBS were elderly. |
T8 | 578-658 | Sentence | denotes | Preceding symptoms like ageusia and hyposmia were unique for COVID-19 infection. |
T9 | 659-792 | Sentence | denotes | Patients with COVID-19-related GBS had a severe disease with respiratory failure due to lobar pneumonia and interstitial pneumonitis. |
T10 | 793-871 | Sentence | denotes | They showed ground-glass appearance of lungs on chest computerized tomography. |
T11 | 872-951 | Sentence | denotes | Increased severity of disease is also evident from the electrophysiology study. |
T12 | 952-1171 | Sentence | denotes | Where demyelinating neuropathy is more common with typical GBS and GBS related to dengue and Zika virus, majority of COVID-19-related GBS patients had axonal motor (AMAN) and axonal motor-sensory polyneuropathy (AMSAN). |
T13 | 1172-1273 | Sentence | denotes | A few of these patients showed enhancement of caudal nerve roots on Gadolinium-enhanced MRI of spine. |
T14 | 1274-1413 | Sentence | denotes | Most COVID-19 patients received hydroxychloroquine, azithromycin, lopinavir and ritonavir in addition to intravenous immunoglobulin (IVIG). |
T15 | 1414-1531 | Sentence | denotes | However, more than half of patients showed poor outcome in the form of long ICU stay, residual paresis and dysphagia. |
T16 | 1532-1634 | Sentence | denotes | Table 1 Differences in the presentation of Typical GBS, Dengue, Zika virus and COVID SARS related GBS. |
T17 | 1635-1719 | Sentence | denotes | Feature Typical GBS Dengue-related GBS Zika virus-related GBS COVID SARS related GBS |
T18 | 1720-3363 | Sentence | denotes | Geographical distributionAgeSexPreceding illnessMean time to GBSInitial symptomsDysphagiaSignsFacial diplegiaDysautonomiaAtaxiaRespiratory failureOther cranial nerves involvedLeukopeniaThrombocytopeniaNerve conductionCT chestMRI Brain/spineTreatmentOutcome GlobalAll age groupsMales 1.5 times more affectedRespiratory or gastrointestinal< 6 weeksParesthesia, pain followed by weakness of limbsLess commonAreflexic quadreparesisCommonCommonLess common25%Ocular nervesUncommonUncommonAIDP--IVIG, PlasmapherisisGood, persistent disability in 20%-30% Latin America, IndiaAll age groupsMales:Females EqualFever, rash, myalgia, headache1–30 daysAscending weakness, paresthesia, facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonLess commonGlossopharyngeal nerveCommonCommonAIDP, AMSAN--IVIG, PlasmapheresisGood Latin America, Europe, East Asia, North AmericalMiddle age to elderlyMore malesFever, headache, rash, arthralgia, diarrhea, conjunctivitis0–10 daysLimb pains, paresthesia, lower limb weakness, facial weaknessMore commonAreflexic quadri/paraparesisCommon (>50%)Common (up to 30%)Common (up to 70%)Less common3rd cranial nerve--AIDP > AMAN, AMSAN--IVIG, PlasmapheresisGood, half may require ICU care China, Iran, Europe, USAUsually elderlyMore malesFever, cough, dyspnea, ageusia, hyposmia5–14 daysParesthesia, lower limb weakness, facial weaknessLess commonAreflexic quadri/paraparesisCommonLess commonLess commonCommon-Common-AMSAN, AMAN, AIDPPneumonia, interstitial pneumonitisEnhancement of caudal nerve rootsIVIG, Lopinavir, ritonavir, HCQ, Azithromycin,Poor, residual weakness, dysphagia, long ICU stay |
T19 | 3364-3504 | Sentence | denotes | AIDP – Acute inflammatory demyelinating polyneuropathy, AMAN – Acute motor axonal neuropathy, AMSAN – Acute motor sensory axonal neuropathy. |
T20 | 3505-3558 | Sentence | denotes | Is COVID-19-related GBS has a different pathogenesis? |
T21 | 3559-3776 | Sentence | denotes | The polyneuropathy in GBS is believed to be due to cross-immunity against epitopes of peripheral nerve components that it shares with the epitopes on the cell surface of bacteria that produces an antecedent infection. |
T22 | 3777-3877 | Sentence | denotes | This mechanism of “molecular mimicry” is best understood with the Campylobacter jejuni -related GBS. |
T23 | 3878-3945 | Sentence | denotes | C. jejuni expresses various gangliosides antigen on its outer core. |
T24 | 3946-4109 | Sentence | denotes | Antecedent infection with C. jejuni results in antibody formation against specific gangliosides present on axonal membrane (GM1, GD1a, GalNac-GD1a, GD1b and GQ1b). |
T25 | 4110-4254 | Sentence | denotes | Presence of these anti-ganglioside antibodies is strongly associated with AMAN, AMSAN and Miller-Fischer variants of GBS (Ogawara et al., 2000). |
T26 | 4255-4360 | Sentence | denotes | The cross-immunity between viral antigens and peripheral nerve glycolipids have not been well-documented. |
T27 | 4361-4466 | Sentence | denotes | Positive GD1a antibody was reported in a few patients with dengue virus-related GBS (Simon et al., 2016). |
T28 | 4467-4587 | Sentence | denotes | Anti-ganglioside antibody was not found in patients with COVID-19 and Zika virus-related GBS (Cao-Lormeau et al., 2016). |
T29 | 4588-4803 | Sentence | denotes | This has led to speculation that the neuropathy in viral infections-related GBS could be due to other autoantibodies that are not detected as yet or the viruses produced nerve damage due to other neurotoxic effects. |
T30 | 4804-4924 | Sentence | denotes | However, there is paucity of evidence of direct infection of peripheral nerves by viruses from the pathological studies. |
T31 | 4925-5044 | Sentence | denotes | Good response to immunotherapy in viral infection-related GBS is also against the direct neurotoxic effects of viruses. |
T32 | 5045-5214 | Sentence | denotes | COVID-19 patients with AIDP responded better as compared to those with axonal variants of GBS; a difference also seen in patients with dengue and Zika virus-related GBS. |
T33 | 5215-5318 | Sentence | denotes | Recently, a good clinical response in pneumonia has been seen in COVID-19 patients with plasma therapy. |
T34 | 5319-5403 | Sentence | denotes | Does plasma therapy produce good recovery in COVID-19-related GBS is yet to be seen. |
T35 | 5405-5438 | Sentence | denotes | Declaration of Competing Interest |
T36 | 5439-5609 | Sentence | denotes | The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
T37 | 5611-5641 | Sentence | denotes | Appendix A Supplementary data |
T38 | 5642-5719 | Sentence | denotes | The following are the Supplementary data to this article:Supplementary data 1 |
T39 | 5721-5736 | Sentence | denotes | Acknowledgement |
T40 | 5737-5742 | Sentence | denotes | None. |
T41 | 5743-5750 | Sentence | denotes | Funding |
T42 | 5751-5788 | Sentence | denotes | The work did not receive any funding. |
T43 | 5789-5901 | Sentence | denotes | Appendix A Supplementary data to this article can be found online at https://doi.org/10.1016/j.bbi.2020.05.051. |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T1 | 4070-4073 | GlycoEpitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
T2 | 4075-4079 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |
T3 | 4081-4092 | GlycoEpitope | denotes | GalNac-GD1a | http://www.glycoepitope.jp/epitopes/EP0058 |
T4 | 4088-4092 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |
T5 | 4094-4098 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
T6 | 4103-4107 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
T7 | 4370-4374 | GlycoEpitope | denotes | GD1a | http://www.glycoepitope.jp/epitopes/EP0056 |