> top > docs > PMC:7235801 > spans > 7833-10711 > annotations

PMC:7235801 / 7833-10711 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
178 492-496 Gene denotes RdRp Gene:43740578
179 573-577 Gene denotes RdRp Gene:43740578
180 708-713 Gene denotes ORF1b Gene:43740578
181 718-719 Gene denotes N Gene:43740575
182 813-818 Gene denotes Orf1b Gene:43740578
183 898-903 Gene denotes ORF1b Gene:43740578
184 1270-1274 Gene denotes RdRp Gene:43740578
185 1275-1283 Gene denotes helicase Gene:164045
186 770-771 Gene denotes N Gene:43740575
187 340-350 Species denotes SARS-CoV-2 Tax:2697049
188 390-403 Species denotes coronaviruses Tax:11118
189 426-436 Species denotes SARS-CoV-2 Tax:2697049
190 731-741 Species denotes SARS-CoV-2 Tax:2697049
191 988-996 Species denotes SARS-CoV Tax:694009
192 1086-1096 Species denotes SARS-CoV-2 Tax:2697049
193 1102-1110 Species denotes SARS-CoV Tax:694009
194 1297-1307 Species denotes SARS-CoV-2 Tax:2697049
195 1346-1351 Species denotes human Tax:9606
196 1352-1365 Species denotes coronaviruses Tax:11118
197 1729-1739 Species denotes SARS-CoV-2 Tax:2697049
198 1942-1952 Species denotes SARS-CoV-2 Tax:2697049
199 2588-2598 Species denotes SARS-CoV-2 Tax:2697049
200 66-74 Disease denotes COVID-19 MESH:C000657245
201 1444-1452 Disease denotes COVID-19 MESH:C000657245
202 2320-2328 Disease denotes COVID-19 MESH:C000657245
203 2372-2392 Disease denotes SARS-CoV-2 infection MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T38 351-354 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T39 437-440 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T40 462-465 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T41 476-479 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T42 498-502 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T43 517-521 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T44 578-582 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T45 772-776 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T46 1516-1522 Body_part denotes saliva http://purl.org/sig/ont/fma/fma59862
T47 1524-1530 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T48 1536-1559 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T49 2178-2184 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T50 2693-2697 Body_part denotes nose http://purl.org/sig/ont/fma/fma46472
T51 2701-2707 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T11 1516-1522 Body_part denotes saliva http://purl.obolibrary.org/obo/UBERON_0001836
T12 1536-1559 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T13 1542-1559 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T14 2693-2697 Body_part denotes nose http://purl.obolibrary.org/obo/UBERON_0000004
T15 2701-2707 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T64 66-74 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T65 340-348 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 426-434 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 731-739 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 988-996 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 1086-1094 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 1102-1110 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 1297-1305 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T72 1444-1452 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 1729-1737 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 1942-1950 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 2320-2328 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 2372-2380 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 2383-2392 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T78 2588-2596 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 2645-2654 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T67 155-156 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T68 409-413 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T69 498-502 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T70 517-521 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T71 578-582 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T72 619-626 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T73 772-776 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T74 844-848 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T75 1023-1030 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T76 1288-1293 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T77 1346-1351 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T78 1382-1389 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T79 1508-1515 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T80 1524-1530 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T81 1703-1710 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test is
T82 1740-1744 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T83 1793-1795 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T84 1843-1844 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 1895-1899 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T86 2030-2034 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T87 2049-2050 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 2189-2192 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89 2329-2333 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T90 2353-2355 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T91 2429-2437 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T92 2510-2511 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 2552-2556 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T94 2626-2633 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T95 2655-2656 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T96 2661-2662 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T97 2693-2697 http://www.ebi.ac.uk/efo/EFO_0000828 denotes nose
T98 2725-2726 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 2750-2751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 2842-2843 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T53 351-354 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T54 437-440 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T55 462-465 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T56 476-479 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T57 2797-2805 Chemical denotes reagents http://purl.obolibrary.org/obo/CHEBI_33893

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T56 0-154 Sentence denotes The most widely used IVD assays for the confirmatory diagnosis of COVID-19 are based on RT-PCR that have been employed globally to deal with the pandemic.
T57 155-312 Sentence denotes A novel and robust real-time RT-PCR assay was developed by Tib-Molbiol, Germany, in collaboration with various partners by the 2nd week of January 2020 [14].
T58 313-404 Sentence denotes It was highly specific for SARS-CoV-2 RNA and did not cross-react with other coronaviruses.
T59 405-510 Sentence denotes The test detects the SARS-CoV-2 RNA via envelope (E) and RNA-dependent RNA polymerase (RdRp) gene assays.
T60 511-627 Sentence denotes The E-gene assay was used for first line screening, while the RdRp gene assay was employed for confirmatory testing.
T61 628-765 Sentence denotes In another approach, the researchers developed one-step RT-PCR assays to detect ORF1b and N regions of SARS-CoV-2 in 1 h and 15 min [15].
T62 766-849 Sentence denotes The N gene assay was used for screening, while Orf1b was used as confirmatory test.
T63 850-1031 Sentence denotes However, as the assay involved the detection of ORF1b and N regions that are highly conserved among sarbecoviruses, it could also bind to SARS-CoV and other closely-related viruses.
T64 1032-1190 Sentence denotes The authors mentioned that they could distinguish the SARS-CoV-2 from SARS-CoV via sequence analysis of positive amplicons if the RT-PCR results are positive.
T65 1191-1395 Sentence denotes Of interest was the development of real-time RT-PCR assay for the detection of RdRp/helicase (H) genes of SARS-CoV-2, which did not cross-react with other human coronaviruses and respiratory viruses [16].
T66 1396-1568 Sentence denotes Due to its high sensitivity, it can be used for COVID-19 detection in samples that have low viral loads and for testing saliva, plasma, and upper respiratory tract samples.
T67 1569-1660 Sentence denotes Many RT-PCR assays have already been developed by many companies and researchers worldwide.
T68 1661-1836 Sentence denotes The most prominent real-time RT-PCR rapid test is the Xpert® Xpress SARS-CoV-2 test by Cepheid, USA, which provides results in just 45 min using GenXpert benchtop system [17].
T69 1837-2025 Sentence denotes It is a rapid and automated point-of-care (POC) molecular test that enables the qualitative detection of SARS-CoV-2 in nasopharyngeal swab, nasal wash, or aspirate specimens from suspects.
T70 2026-2185 Sentence denotes The test requires only a minute for sample preparation, employs Cepheid’s Xpert® Xpress cartridge technology, and targets multiple regions of the viral genome.
T71 2186-2276 Sentence denotes It has also received Food and Drug Administration (FDA) emergency use authorization (EUA).
T72 2277-2424 Sentence denotes Another prominent advance is the Vivalytic COVID-19 test by Bosch, Germany [18], which detects SARS-CoV-2 infection in suspects in less than 2.5 h.
T73 2425-2503 Sentence denotes The test was developed by Bosch in collaboration with Randox Laboratories, UK.
T74 2504-2663 Sentence denotes It is a fully automated and rapid POC molecular test that can simultaneously detect SARS-CoV-2 and nine other respiratory viruses, including influenza A and B.
T75 2664-2806 Sentence denotes The sample is taken from the nose or throat of suspect using a swab and placed inside a Vivalytic cartridge containing all the assay reagents.
T76 2807-2878 Sentence denotes The cartridge is then plugged into a small benchtop Vivalytic analyzer.