PMC:7228307 / 53799-54061 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1104","span":{"begin":182,"end":186},"obj":"Gene"},{"id":"1105","span":{"begin":51,"end":55},"obj":"Gene"}],"attributes":[{"id":"A1104","pred":"tao:has_database_id","subj":"1104","obj":"Gene:2213"},{"id":"A1105","pred":"tao:has_database_id","subj":"1105","obj":"Gene:2213"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T411","span":{"begin":130,"end":139},"obj":"Body_part"}],"attributes":[{"id":"A411","pred":"fma_id","subj":"T411","obj":"http://purl.org/sig/ont/fma/fma13478"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T908","span":{"begin":6,"end":8},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T909","span":{"begin":51,"end":53},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T910","span":{"begin":150,"end":151},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T911","span":{"begin":182,"end":184},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T70545","span":{"begin":56,"end":64},"obj":"Chemical"},{"id":"T34","span":{"begin":243,"end":251},"obj":"Chemical"}],"attributes":[{"id":"A70007","pred":"chebi_id","subj":"T70545","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"},{"id":"A5650","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T228","span":{"begin":65,"end":74},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"},{"id":"T229","span":{"begin":252,"end":261},"obj":"http://purl.obolibrary.org/obo/BFO_0000034"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1104","span":{"begin":182,"end":186},"obj":"Gene"},{"id":"1105","span":{"begin":51,"end":55},"obj":"Gene"}],"attributes":[{"id":"A1104","pred":"pubann:denotes","subj":"1104","obj":"Gene:2213"},{"id":"A1105","pred":"pubann:denotes","subj":"1105","obj":"Gene:2213"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T306","span":{"begin":0,"end":262},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T410","span":{"begin":130,"end":139},"obj":"Body_part"}],"attributes":[{"id":"A410","pred":"fma_id","subj":"T410","obj":"http://purl.org/sig/ont/fma/fma13478"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}

{"project":"LitCovid-sentences","denotations":[{"id":"T306","span":{"begin":0,"end":262},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, Fc engineering is an effective way to remove FcγR effector functions and may be preferable to using unmodified IgG2 or IgG4 backbones that have a more restricted repertoire of FcγR interactions but which are still able to induce certain effector functions."}