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PMC:7228307 / 53201-53475 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
1090 254-258 Gene denotes FcγR Gene:2213
1091 53-57 Gene denotes FcγR Gene:2213
1094 14-40 Disease denotes PD‐1 antibody tislelizumab MESH:D010300
1095 169-174 Mutation denotes E233P p.E233P
1096 176-181 Mutation denotes F234V rs755807976
1097 183-188 Mutation denotes L235A p.L235A
1098 216-221 Mutation denotes D265A p.D265A

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T409 19-27 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T898 41-44 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T899 53-55 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T900 106-110 http://purl.obolibrary.org/obo/CLO_0007179 denotes L235
T901 166-167 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T902 246-247 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T903 254-256 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T85014 14-16 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes pubann:has_HGVS_notation
1090 254-258 Gene denotes FcγR Gene:2213
1091 53-57 Gene denotes FcγR Gene:2213
1094 14-40 Disease denotes PD‐1 antibody tislelizumab MESH:D010300
1095 169-174 Mutation denotes E233P p.E233P
1096 176-181 Mutation denotes F234V rs755807976
1097 183-188 Mutation denotes L235A p.L235A
1098 216-221 Mutation denotes D265A p.D265A

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T303 0-274 Sentence denotes The IgG4 anti‐PD‐1 antibody tislelizumab has had its FcγR contact residues in the lower hinge E233, F234, L235 substituted with the equivalent residues of IgG2 P, V, A (E233P, F234V, L235A) as well as the additional D265A mutation which disrupts a major FcγR contact in CH2.

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T715 14-18 Protein denotes PD‐1 https://www.uniprot.org/uniprot/Q7M4M5|https://www.uniprot.org/uniprot/Q6NZ54|https://www.uniprot.org/uniprot/Q3KQW2|https://www.uniprot.org/uniprot/P18621|https://www.uniprot.org/uniprot/J3QL51|https://www.uniprot.org/uniprot/B5ME31|https://www.uniprot.org/uniprot/B4E3C2|https://www.uniprot.org/uniprot/B2R4H3

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T408 19-27 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T303 0-274 Sentence denotes The IgG4 anti‐PD‐1 antibody tislelizumab has had its FcγR contact residues in the lower hinge E233, F234, L235 substituted with the equivalent residues of IgG2 P, V, A (E233P, F234V, L235A) as well as the additional D265A mutation which disrupts a major FcγR contact in CH2.