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PMC:7228307 / 45239-45459 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
809 160-164 Gene denotes FcγR Gene:2213
810 135-139 Gene denotes FcγR Gene:2213
817 14-18 Gene denotes PD‐1 Gene:5133
835 26-31 Mutation denotes S228P rs1469294455
849 47-52 Mutation denotes L235A p.L235A
853 33-38 Mutation denotes E233P p.E233P
854 40-45 Mutation denotes F234V rs755807976
856 54-59 Mutation denotes D265A p.D265A
857 61-66 Mutation denotes L309V p.L309V
858 68-73 Mutation denotes R409K p.R409K

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T796 135-137 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T797 160-162 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T233 14-16 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes pubann:has_HGVS_notation
809 160-164 Gene denotes FcγR Gene:2213
810 135-139 Gene denotes FcγR Gene:2213
817 14-18 Gene denotes PD‐1 Gene:5133
835 26-31 Mutation denotes S228P rs1469294455
849 47-52 Mutation denotes L235A p.L235A
853 33-38 Mutation denotes E233P p.E233P
854 40-45 Mutation denotes F234V rs755807976
856 54-59 Mutation denotes D265A p.D265A
857 61-66 Mutation denotes L309V p.L309V
858 68-73 Mutation denotes R409K p.R409K

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T262 0-220 Sentence denotes Tislelizumab PD‐1 IgG4 S228P; E233P; F234V; L235A; D265A; L309V; R409K Stabilize core hinge; mimic IgG2 lower hinge for restricted FcγR specificity; ablate FcγR binding; stabilize CH3 interaction Oncology Phase III

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T559 14-18 Protein denotes PD‐1 https://www.uniprot.org/uniprot/Q7M4M5|https://www.uniprot.org/uniprot/Q6NZ54|https://www.uniprot.org/uniprot/Q3KQW2|https://www.uniprot.org/uniprot/P18621|https://www.uniprot.org/uniprot/J3QL51|https://www.uniprot.org/uniprot/B5ME31|https://www.uniprot.org/uniprot/B4E3C2|https://www.uniprot.org/uniprot/B2R4H3

LitCovid-sample-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T28 201-209 Phenotype denotes Oncology http://purl.obolibrary.org/obo/HP_0002664

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T262 0-220 Sentence denotes Tislelizumab PD‐1 IgG4 S228P; E233P; F234V; L235A; D265A; L309V; R409K Stabilize core hinge; mimic IgG2 lower hinge for restricted FcγR specificity; ablate FcγR binding; stabilize CH3 interaction Oncology Phase III

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T28 201-209 Phenotype denotes Oncology http://purl.obolibrary.org/obo/HP_0002664