PMC:7228307 / 45239-45459
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id | tao:has_standard_notation |
---|---|---|---|---|---|---|
809 | 160-164 | Gene | denotes | FcγR | Gene:2213 | |
810 | 135-139 | Gene | denotes | FcγR | Gene:2213 | |
817 | 14-18 | Gene | denotes | PD‐1 | Gene:5133 | |
835 | 26-31 | Mutation | denotes | S228P | rs1469294455 | |
849 | 47-52 | Mutation | denotes | L235A | p.L235A | |
853 | 33-38 | Mutation | denotes | E233P | p.E233P | |
854 | 40-45 | Mutation | denotes | F234V | rs755807976 | |
856 | 54-59 | Mutation | denotes | D265A | p.D265A | |
857 | 61-66 | Mutation | denotes | L309V | p.L309V | |
858 | 68-73 | Mutation | denotes | R409K | p.R409K |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T796 | 135-137 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T797 | 160-162 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T233 | 14-16 | Chemical | denotes | PD | http://purl.obolibrary.org/obo/CHEBI_74756 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes | pubann:has_HGVS_notation |
---|---|---|---|---|---|---|
809 | 160-164 | Gene | denotes | FcγR | Gene:2213 | |
810 | 135-139 | Gene | denotes | FcγR | Gene:2213 | |
817 | 14-18 | Gene | denotes | PD‐1 | Gene:5133 | |
835 | 26-31 | Mutation | denotes | S228P | rs1469294455 | |
849 | 47-52 | Mutation | denotes | L235A | p.L235A | |
853 | 33-38 | Mutation | denotes | E233P | p.E233P | |
854 | 40-45 | Mutation | denotes | F234V | rs755807976 | |
856 | 54-59 | Mutation | denotes | D265A | p.D265A | |
857 | 61-66 | Mutation | denotes | L309V | p.L309V | |
858 | 68-73 | Mutation | denotes | R409K | p.R409K |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T262 | 0-220 | Sentence | denotes | Tislelizumab PD‐1 IgG4 S228P; E233P; F234V; L235A; D265A; L309V; R409K Stabilize core hinge; mimic IgG2 lower hinge for restricted FcγR specificity; ablate FcγR binding; stabilize CH3 interaction Oncology Phase III |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T559 | 14-18 | Protein | denotes | PD‐1 | https://www.uniprot.org/uniprot/Q7M4M5|https://www.uniprot.org/uniprot/Q6NZ54|https://www.uniprot.org/uniprot/Q3KQW2|https://www.uniprot.org/uniprot/P18621|https://www.uniprot.org/uniprot/J3QL51|https://www.uniprot.org/uniprot/B5ME31|https://www.uniprot.org/uniprot/B4E3C2|https://www.uniprot.org/uniprot/B2R4H3 |
LitCovid-sample-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T28 | 201-209 | Phenotype | denotes | Oncology | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T262 | 0-220 | Sentence | denotes | Tislelizumab PD‐1 IgG4 S228P; E233P; F234V; L235A; D265A; L309V; R409K Stabilize core hinge; mimic IgG2 lower hinge for restricted FcγR specificity; ablate FcγR binding; stabilize CH3 interaction Oncology Phase III |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T28 | 201-209 | Phenotype | denotes | Oncology | http://purl.obolibrary.org/obo/HP_0002664 |