PMC:7228307 / 43643-43772 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"813","span":{"begin":97,"end":101},"obj":"Gene"},{"id":"818","span":{"begin":12,"end":17},"obj":"Gene"},{"id":"828","span":{"begin":25,"end":30},"obj":"Mutation"},{"id":"829","span":{"begin":32,"end":37},"obj":"Mutation"},{"id":"830","span":{"begin":39,"end":44},"obj":"Mutation"}],"attributes":[{"id":"A813","pred":"tao:has_database_id","subj":"813","obj":"Gene:2213"},{"id":"A818","pred":"tao:has_database_id","subj":"818","obj":"Gene:29126"},{"id":"A828","pred":"tao:has_standard_notation","subj":"828","obj":"p.L234F"},{"id":"A829","pred":"tao:has_standard_notation","subj":"829","obj":"p.L235E"},{"id":"A830","pred":"tao:has_standard_notation","subj":"830","obj":"p.P331S"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T775","span":{"begin":12,"end":17},"obj":"http://purl.obolibrary.org/obo/CLO_0008407"},{"id":"T776","span":{"begin":97,"end":99},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T225","span":{"begin":12,"end":14},"obj":"Chemical"}],"attributes":[{"id":"A225","pred":"chebi_id","subj":"T225","obj":"http://purl.obolibrary.org/obo/CHEBI_74756"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-sample-Pubtator

    {"project":"LitCovid-sample-Pubtator","denotations":[{"id":"813","span":{"begin":97,"end":101},"obj":"Gene"},{"id":"818","span":{"begin":12,"end":17},"obj":"Gene"},{"id":"828","span":{"begin":25,"end":30},"obj":"Mutation"},{"id":"829","span":{"begin":32,"end":37},"obj":"Mutation"},{"id":"830","span":{"begin":39,"end":44},"obj":"Mutation"}],"attributes":[{"id":"A813","pred":"pubann:denotes","subj":"813","obj":"Gene:2213"},{"id":"A818","pred":"pubann:denotes","subj":"818","obj":"Gene:29126"},{"id":"A828","pred":"pubann:has_HGVS_notation","subj":"828","obj":"p.L234F"},{"id":"A829","pred":"pubann:has_HGVS_notation","subj":"829","obj":"p.L235E"},{"id":"A830","pred":"pubann:has_HGVS_notation","subj":"830","obj":"p.P331S"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-sample-sentences

    {"project":"LitCovid-sample-sentences","denotations":[{"id":"T248","span":{"begin":0,"end":129},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-sample-UniProt

    {"project":"LitCovid-sample-UniProt","denotations":[{"id":"T471","span":{"begin":12,"end":17},"obj":"Protein"}],"attributes":[{"id":"A471","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q9NZQ7"},{"id":"A472","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q9NUZ5"},{"id":"A473","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q9EP73"},{"id":"A474","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q6WEX4"},{"id":"A475","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q66RK1"},{"id":"A476","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q2V8D5"},{"id":"A477","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/Q14CJ2"},{"id":"A478","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/B4DU27"},{"id":"A479","pred":"uniprot_id","subj":"T471","obj":"https://www.uniprot.org/uniprot/B2RBA2"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-sample-PD-HP

    {"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T19","span":{"begin":111,"end":119},"obj":"Phenotype"}],"attributes":[{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T248","span":{"begin":0,"end":129},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T19","span":{"begin":111,"end":119},"obj":"Phenotype"}],"attributes":[{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"Durvalumab PD‐L1 IgG1 L234F; L235E; P331S Mimic IgG4 hinge and its CH2 F/G loop; plus ablate FcγR binding Oncology Marketed"}