PMC:7228307 / 41489-41938 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7228307","sourcedb":"PMC","sourceid":"7228307","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7228307","text":"Thus, the relative contributions of the activating (A) and inhibitory (I) FcγR to the response by an effector cell, the A‐to‐I ratio, may be an important determinant in clinical outcome of therapeutic mAb activity,76, 81, 82 that is, the higher the A‐to‐I ratio, the greater the proinflammatory response induced by the therapeutic mAb or conversely the lower the A‐to‐I ratio, the greater the inhibition or dampening of the proinflammatory response.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"690","span":{"begin":74,"end":78},"obj":"Gene"}],"attributes":[{"id":"A690","pred":"tao:has_database_id","subj":"690","obj":"Gene:2213"},{"subj":"690","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T358","span":{"begin":110,"end":114},"obj":"Body_part"}],"attributes":[{"id":"A358","pred":"fma_id","subj":"T358","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T358","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T745","span":{"begin":40,"end":50},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T746","span":{"begin":52,"end":53},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T747","span":{"begin":74,"end":76},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T748","span":{"begin":110,"end":114},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T749","span":{"begin":120,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T750","span":{"begin":205,"end":213},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T751","span":{"begin":249,"end":250},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T752","span":{"begin":363,"end":364},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T745","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T746","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T747","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T748","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T749","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T750","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T751","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T752","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T217","span":{"begin":101,"end":109},"obj":"Chemical"}],"attributes":[{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T211","span":{"begin":110,"end":114},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"attributes":[{"subj":"T211","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"690","span":{"begin":74,"end":78},"obj":"Gene"}],"attributes":[{"id":"A690","pred":"pubann:denotes","subj":"690","obj":"Gene:2213"},{"subj":"690","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T234","span":{"begin":0,"end":449},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T234","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T357","span":{"begin":110,"end":114},"obj":"Body_part"}],"attributes":[{"id":"A357","pred":"fma_id","subj":"T357","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T357","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T234","span":{"begin":0,"end":449},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T234","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#d1ec93","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93eb"},{"id":"LitCovid-PD-CLO","color":"#93ecd3"},{"id":"LitCovid-PD-CHEBI","color":"#ecb993"},{"id":"LitCovid-sample-PD-IDO","color":"#9f93ec"},{"id":"LitCovid-sample-Pubtator","color":"#a0ec93"},{"id":"LitCovid-sample-sentences","color":"#ec93bb"},{"id":"LitCovid-sample-PD-FMA","color":"#93d5ec"},{"id":"LitCovid-sentences","color":"#ece993"}]}]}}