PMC:7228307 / 3968-4301 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"49","span":{"begin":291,"end":295},"obj":"Gene"}],"attributes":[{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:2213"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T23","span":{"begin":59,"end":62},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T13","span":{"begin":314,"end":320},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T41","span":{"begin":41,"end":42},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T42","span":{"begin":78,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T43","span":{"begin":130,"end":140},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T44","span":{"begin":146,"end":148},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T45","span":{"begin":149,"end":151},"obj":"http://purl.obolibrary.org/obo/CLO_0008882"},{"id":"T46","span":{"begin":291,"end":293},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":249,"end":257},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T20","span":{"begin":196,"end":205},"obj":"http://purl.obolibrary.org/obo/IDO_0000528"},{"id":"T21","span":{"begin":328,"end":332},"obj":"http://purl.obolibrary.org/obo/IDO_0000531"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"49","span":{"begin":291,"end":295},"obj":"Gene"}],"attributes":[{"id":"A49","pred":"pubann:denotes","subj":"49","obj":"Gene:2213"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T23","span":{"begin":0,"end":333},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T23","span":{"begin":59,"end":62},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T10","span":{"begin":314,"end":320},"obj":"Disease"}],"attributes":[{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}

{"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":0,"end":333},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In normal homeostatic immunity, there is a balance between IgG immune complex activation of proinflammatory responses through the activating‐type FcγRs—which leads to the destruction of opsonized pathogens—and of the modulation of these destructive effector responses by the inhibitory‐type FcγR, thereby avoiding injury to the host."}