PMC:7228307 / 38904-39234 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"645","span":{"begin":205,"end":212},"obj":"Gene"},{"id":"646","span":{"begin":135,"end":139},"obj":"Gene"}],"attributes":[{"id":"A645","pred":"tao:has_database_id","subj":"645","obj":"Gene:2213"},{"id":"A646","pred":"tao:has_database_id","subj":"646","obj":"Gene:2213"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T346","span":{"begin":313,"end":321},"obj":"Body_part"}],"attributes":[{"id":"A346","pred":"fma_id","subj":"T346","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T58","span":{"begin":298,"end":302},"obj":"Disease"},{"id":"T59","span":{"begin":304,"end":308},"obj":"Disease"}],"attributes":[{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0008734"},{"id":"A59","pred":"mondo_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/MONDO_0022697"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T702","span":{"begin":23,"end":24},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T703","span":{"begin":54,"end":60},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T704","span":{"begin":121,"end":122},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T705","span":{"begin":135,"end":137},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T706","span":{"begin":177,"end":178},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T707","span":{"begin":205,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T708","span":{"begin":265,"end":275},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T709","span":{"begin":281,"end":283},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T710","span":{"begin":284,"end":286},"obj":"http://purl.obolibrary.org/obo/CLO_0008882"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T206","span":{"begin":45,"end":53},"obj":"Chemical"},{"id":"T207","span":{"begin":140,"end":146},"obj":"Chemical"},{"id":"T208","span":{"begin":179,"end":185},"obj":"Chemical"}],"attributes":[{"id":"A206","pred":"chebi_id","subj":"T206","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"},{"id":"A207","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A208","pred":"chebi_id","subj":"T208","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"645","span":{"begin":205,"end":212},"obj":"Gene"},{"id":"646","span":{"begin":135,"end":139},"obj":"Gene"}],"attributes":[{"id":"A645","pred":"pubann:denotes","subj":"645","obj":"Gene:2213"},{"id":"A646","pred":"pubann:denotes","subj":"646","obj":"Gene:2213"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T221","span":{"begin":0,"end":330},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T345","span":{"begin":313,"end":321},"obj":"Body_part"}],"attributes":[{"id":"A345","pred":"fma_id","subj":"T345","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T94","span":{"begin":95,"end":113},"obj":"http://purl.obolibrary.org/obo/GO_0006956"},{"id":"T95","span":{"begin":298,"end":302},"obj":"http://purl.obolibrary.org/obo/GO_0001788"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T95","span":{"begin":95,"end":113},"obj":"http://purl.obolibrary.org/obo/GO_0006956"},{"id":"T96","span":{"begin":298,"end":302},"obj":"http://purl.obolibrary.org/obo/GO_0001788"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T95","span":{"begin":95,"end":113},"obj":"http://purl.obolibrary.org/obo/GO_0006956"},{"id":"T96","span":{"begin":298,"end":302},"obj":"http://purl.obolibrary.org/obo/GO_0001788"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}

{"project":"LitCovid-sentences","denotations":[{"id":"T221","span":{"begin":0,"end":330},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"IgG1 is, in many ways, a proinflammatory or “effector‐active” subclass, as it can initiate the complement cascade and is a “universal” FcγR ligand.74 Notwithstanding it is also a ligand for the inhibitory FcγRIIb, IgG1 elicits proinflammatory responses through all activating‐type FcγRs, including ADCC, ADCP and cytokine release."}