PMC:7228307 / 34976-35230 JSONTXT

{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T1","span":{"begin":212,"end":218},"obj":"https://glytoucan.org/Structures/Glycans/G82576YO"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-PubTator","denotations":[{"id":"604","span":{"begin":152,"end":160},"obj":"Gene"},{"id":"606","span":{"begin":28,"end":32},"obj":"Gene"},{"id":"612","span":{"begin":212,"end":218},"obj":"Chemical"},{"id":"613","span":{"begin":236,"end":251},"obj":"Chemical"}],"attributes":[{"id":"A604","pred":"tao:has_database_id","subj":"604","obj":"Gene:2214"},{"id":"A606","pred":"tao:has_database_id","subj":"606","obj":"Gene:2213"},{"id":"A612","pred":"tao:has_database_id","subj":"612","obj":"MESH:D005643"},{"id":"A613","pred":"tao:has_database_id","subj":"613","obj":"MESH:D009844"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T333","span":{"begin":131,"end":134},"obj":"Body_part"},{"id":"T334","span":{"begin":212,"end":218},"obj":"Body_part"},{"id":"T335","span":{"begin":236,"end":251},"obj":"Body_part"}],"attributes":[{"id":"A333","pred":"fma_id","subj":"T333","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A334","pred":"fma_id","subj":"T334","obj":"http://purl.org/sig/ont/fma/fma82790"},{"id":"A335","pred":"fma_id","subj":"T335","obj":"http://purl.org/sig/ont/fma/fma82742"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T671","span":{"begin":28,"end":30},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T672","span":{"begin":152,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T673","span":{"begin":233,"end":235},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T190","span":{"begin":212,"end":218},"obj":"Chemical"},{"id":"T191","span":{"begin":236,"end":251},"obj":"Chemical"}],"attributes":[{"id":"A190","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_33984"},{"id":"A191","pred":"chebi_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/CHEBI_50699"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T38","span":{"begin":212,"end":218},"obj":"Chemical"},{"id":"T39","span":{"begin":236,"end":251},"obj":"Chemical"}],"attributes":[{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_33984"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_50699"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"604","span":{"begin":152,"end":160},"obj":"Gene"},{"id":"606","span":{"begin":28,"end":32},"obj":"Gene"},{"id":"612","span":{"begin":212,"end":218},"obj":"Chemical"},{"id":"613","span":{"begin":236,"end":251},"obj":"Chemical"}],"attributes":[{"id":"A604","pred":"pubann:denotes","subj":"604","obj":"Gene:2214"},{"id":"A606","pred":"pubann:denotes","subj":"606","obj":"Gene:2213"},{"id":"A612","pred":"pubann:denotes","subj":"612","obj":"MESH:D005643"},{"id":"A613","pred":"pubann:denotes","subj":"613","obj":"MESH:D009844"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T201","span":{"begin":0,"end":254},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T332","span":{"begin":131,"end":134},"obj":"Body_part"},{"id":"T333","span":{"begin":212,"end":218},"obj":"Body_part"},{"id":"T334","span":{"begin":236,"end":251},"obj":"Body_part"}],"attributes":[{"id":"A332","pred":"fma_id","subj":"T332","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A333","pred":"fma_id","subj":"T333","obj":"http://purl.org/sig/ont/fma/fma82790"},{"id":"A334","pred":"fma_id","subj":"T334","obj":"http://purl.org/sig/ont/fma/fma82742"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}

{"project":"LitCovid-sentences","denotations":[{"id":"T201","span":{"begin":0,"end":254},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Indeed, its removal ablates FcγR binding.67 Of particular relevance to therapeutic mAb development is that the normal low‐affinity IgG interaction with FcγRIIIa is profoundly increased by the removal of the core fucose from the N297 Fc oligosaccharide.68"}