PMC:7228307 / 3200-3574 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"43","span":{"begin":102,"end":120},"obj":"Disease"},{"id":"44","span":{"begin":163,"end":172},"obj":"Disease"},{"id":"45","span":{"begin":200,"end":207},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:D001327"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:D007239"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"MESH:D004342"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T14","span":{"begin":89,"end":98},"obj":"Body_part"},{"id":"T15","span":{"begin":176,"end":190},"obj":"Body_part"},{"id":"T16","span":{"begin":191,"end":196},"obj":"Body_part"},{"id":"T17","span":{"begin":192,"end":194},"obj":"Body_part"},{"id":"T18","span":{"begin":238,"end":242},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma62875"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T9","span":{"begin":102,"end":120},"obj":"Disease"},{"id":"T10","span":{"begin":154,"end":172},"obj":"Disease"},{"id":"T11","span":{"begin":163,"end":172},"obj":"Disease"},{"id":"T12","span":{"begin":200,"end":207},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0007179"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0005271"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T33","span":{"begin":154,"end":159},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T34","span":{"begin":238,"end":242},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T35","span":{"begin":243,"end":253},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T11","span":{"begin":229,"end":237},"obj":"Chemical"}],"attributes":[{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T5","span":{"begin":176,"end":190},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T6","span":{"begin":192,"end":194},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A5","pred":"meddra_id","subj":"T5","obj":"http://purl.bioontology.org/ontology/MEDDRA/10021496"},{"id":"A6","pred":"meddra_id","subj":"T6","obj":"http://purl.bioontology.org/ontology/MEDDRA/10021496"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T15","span":{"begin":113,"end":120},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"},{"id":"T16","span":{"begin":154,"end":159},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T17","span":{"begin":163,"end":172},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"},{"id":"T18","span":{"begin":238,"end":242},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"43","span":{"begin":102,"end":120},"obj":"Disease"},{"id":"44","span":{"begin":163,"end":172},"obj":"Disease"},{"id":"45","span":{"begin":200,"end":207},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"pubann:denotes","subj":"43","obj":"MESH:D001327"},{"id":"A44","pred":"pubann:denotes","subj":"44","obj":"MESH:D007239"},{"id":"A45","pred":"pubann:denotes","subj":"45","obj":"MESH:D004342"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T21","span":{"begin":0,"end":374},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T14","span":{"begin":89,"end":98},"obj":"Body_part"},{"id":"T15","span":{"begin":176,"end":190},"obj":"Body_part"},{"id":"T16","span":{"begin":191,"end":196},"obj":"Body_part"},{"id":"T17","span":{"begin":192,"end":194},"obj":"Body_part"},{"id":"T18","span":{"begin":238,"end":242},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma62875"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T3","span":{"begin":238,"end":253},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T4","span":{"begin":312,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T5","span":{"begin":325,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0097194"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T7","span":{"begin":102,"end":120},"obj":"Disease"},{"id":"T8","span":{"begin":154,"end":172},"obj":"Disease"},{"id":"T9","span":{"begin":200,"end":207},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0007179"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005271"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T2","span":{"begin":102,"end":120},"obj":"Phenotype"},{"id":"T3","span":{"begin":200,"end":207},"obj":"Phenotype"}],"attributes":[{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002960"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0012393"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T3","span":{"begin":238,"end":253},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T4","span":{"begin":312,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T5","span":{"begin":325,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0097194"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T3","span":{"begin":238,"end":253},"obj":"http://purl.obolibrary.org/obo/GO_0001775"},{"id":"T4","span":{"begin":312,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T5","span":{"begin":325,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0097194"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-sentences","denotations":[{"id":"T21","span":{"begin":0,"end":374},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T2","span":{"begin":102,"end":120},"obj":"Phenotype"},{"id":"T3","span":{"begin":200,"end":207},"obj":"Phenotype"}],"attributes":[{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002960"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0012393"}],"text":"The therapeutic actions of mAbs can take many forms—neutralization of the target such as cytokines in autoimmune disease, clearance of the target such as virus in infection or immunoglobulin (Ig)E in allergy, induction of innate effector cell activation that leads to target destruction by direct killing or the induction of apoptosis and the induction of adaptive immunity."}