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PMC:7228307 / 24380-24962 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
432 100-104 Gene denotes FcγR Gene:2213
433 348-354 Chemical denotes glycan MESH:D011134

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T248 125-138 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T249 125-129 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T468 48-50 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T469 100-102 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T470 105-117 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T471 125-129 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T472 130-138 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T473 326-328 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T474 362-363 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T475 529-531 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T476 544-546 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T125 329-340 Chemical denotes polypeptide http://purl.obolibrary.org/obo/CHEBI_15841
T126 452-463 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T127 512-520 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T143 105-117 http://purl.obolibrary.org/obo/OBI_0100026 denotes organization
T144 125-129 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T145 369-377 http://purl.obolibrary.org/obo/BFO_0000034 denotes function
T146 571-581 http://purl.obolibrary.org/obo/IDO_0000607 denotes productive

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T27 329-340 Chemical denotes polypeptide http://purl.obolibrary.org/obo/CHEBI_15841

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
432 100-104 Gene denotes FcγR Gene:2213
433 348-354 Chemical denotes glycan MESH:D011134

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T141 0-244 Sentence denotes Clearly, the effects of immune complex valency, Fc density, presentation and geometry together with FcγR organization in the cell membrane suggest that the development of mAbs to certain targets will be heavily influenced by the context of use.
T142 245-361 Sentence denotes Thus, improved mAb potency may not necessarily be achieved by engineering of the Fc polypeptide or its glycan alone.
T143 362-582 Sentence denotes A more function‐oriented approach early in mAb selection and development by, for example, application of rapid screening technologies that select for effector potency,34 followed by Fc engineering may be more productive.

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T247 125-138 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T248 125-129 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T141 0-244 Sentence denotes Clearly, the effects of immune complex valency, Fc density, presentation and geometry together with FcγR organization in the cell membrane suggest that the development of mAbs to certain targets will be heavily influenced by the context of use.
T142 245-361 Sentence denotes Thus, improved mAb potency may not necessarily be achieved by engineering of the Fc polypeptide or its glycan alone.
T143 362-582 Sentence denotes A more function‐oriented approach early in mAb selection and development by, for example, application of rapid screening technologies that select for effector potency,34 followed by Fc engineering may be more productive.