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PMC:7228307 / 17304-18321 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
354 380-387 Gene denotes FcγRIIb Gene:2213
355 440-448 Gene denotes FcγRIIb1 Gene:1555
356 594-617 Gene denotes B‐cell antigen receptor Gene:613
357 619-622 Gene denotes BCR Gene:613
358 845-853 Gene denotes FcγRIIb1 Gene:1555
359 315-319 Gene denotes FcγR Gene:2213
360 33-37 Gene denotes FcγR Gene:2213
361 1003-1008 Species denotes human Tax:9606

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T178 62-66 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T179 244-248 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T180 339-344 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T181 412-418 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T182 477-490 Body_part denotes B lymphocytes http://purl.org/sig/ont/fma/fma62869
T183 505-515 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T184 516-527 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T185 596-600 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T186 682-691 Body_part denotes basophils http://purl.org/sig/ont/fma/fma62862
T187 696-707 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T188 741-751 Body_part denotes mast cells http://purl.org/sig/ont/fma/fma66784
T189 746-751 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T190 753-768 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T191 763-768 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T192 778-787 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T193 788-799 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T194 820-831 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T195 1011-1016 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T8 412-418 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T329 0-2 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T330 33-35 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T331 53-54 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 62-66 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T333 104-113 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T334 242-248 http://purl.obolibrary.org/obo/CL_0000236 denotes B‐cell
T335 249-259 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T336 299-309 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T337 315-317 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T338 339-344 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T339 380-382 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T340 440-442 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T341 477-478 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T342 500-504 http://purl.obolibrary.org/obo/CLO_0001564 denotes a 20
T343 500-504 http://purl.obolibrary.org/obo/CLO_0050194 denotes a 20
T344 552-560 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T345 594-600 http://purl.obolibrary.org/obo/CL_0000236 denotes B‐cell
T346 625-627 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T347 746-751 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T348 753-768 http://purl.obolibrary.org/obo/CL_0000451 denotes dendritic cells
T349 778-787 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T350 801-803 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T351 845-847 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T352 914-924 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T353 959-961 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T354 1003-1008 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T355 1009-1016 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T81 272-279 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T82 505-515 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T83 505-510 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T84 511-515 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T85 601-608 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T104 244-248 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T105 320-328 http://purl.obolibrary.org/obo/BFO_0000034 denotes function
T106 339-344 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T107 596-600 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T108 746-751 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T109 763-768 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T110 1011-1016 http://purl.obolibrary.org/obo/CL_0000000 denotes cells

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T13 505-515 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
354 380-387 Gene denotes FcγRIIb Gene:2213
355 440-448 Gene denotes FcγRIIb1 Gene:1555
356 594-617 Gene denotes B‐cell antigen receptor Gene:613
357 619-622 Gene denotes BCR Gene:613
358 845-853 Gene denotes FcγRIIb1 Gene:1555
359 315-319 Gene denotes FcγR Gene:2213
360 33-37 Gene denotes FcγR Gene:2213
361 1003-1008 Species denotes human Tax:9606

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T26 1003-1008 Species denotes human NCBItxid:9606

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T107 0-67 Sentence denotes FcγRIIbs are the inhibitory‐type FcγR and arise from a single gene.
T108 68-149 Sentence denotes They lack intrinsic proinflammatory signaling and are instead immune checkpoints.
T109 150-280 Sentence denotes They provide feedback regulation by antibodies, in the form of immune complexes, to inhibit B‐cell activation by specific antigen.
T110 281-345 Sentence denotes They also control activating‐type FcγR function on innate cells.
T111 346-439 Sentence denotes Two major splice variant forms of FcγRIIb exist with differential tissue expression profiles.
T112 440-624 Sentence denotes FcγRIIb1 preferentially expressed on B lymphocytes contains a 20‐amino acid cytoplasmic insertion necessary for membrane retention and cocapping with the B‐cell antigen receptor (BCR).
T113 625-800 Sentence denotes FcγRIIb2 is the predominant inhibitory receptor found on basophils and neutrophils, as well as on subpopulations of mast cells, dendritic cells and some monocytes/macrophages.
T114 801-1017 Sentence denotes FcγRIIb2 lacks the cytoplasmic insertion of FcγRIIb1 and consequently can internalize rapidly including with the activating FcR when they are co‐cross‐linked.11 It is not clear which form is present on human T cells.

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T8 412-418 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T91 741-745 Protein denotes mast https://www.uniprot.org/uniprot/Q9NL57|https://www.uniprot.org/uniprot/Q9NBD7|https://www.uniprot.org/uniprot/A4V279

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T177 62-66 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T178 244-248 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T179 339-344 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T180 412-418 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T181 477-490 Body_part denotes B lymphocytes http://purl.org/sig/ont/fma/fma62869
T182 505-515 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T183 516-527 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T184 596-600 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T185 682-691 Body_part denotes basophils http://purl.org/sig/ont/fma/fma62862
T186 696-707 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T187 741-751 Body_part denotes mast cells http://purl.org/sig/ont/fma/fma66784
T188 746-751 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T189 753-768 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T190 763-768 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T191 778-787 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T192 788-799 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T193 820-831 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T194 1011-1016 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T37 104-113 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T38 172-182 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T39 234-259 http://purl.obolibrary.org/obo/GO_0050869 denotes inhibit B‐cell activation
T40 242-259 http://purl.obolibrary.org/obo/GO_0042113 denotes B‐cell activation
T41 244-259 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T42 561-570 http://purl.obolibrary.org/obo/GO_0051235 denotes retention

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T37 104-113 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T38 172-182 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T39 234-259 http://purl.obolibrary.org/obo/GO_0050869 denotes inhibit B‐cell activation
T40 242-259 http://purl.obolibrary.org/obo/GO_0042113 denotes B‐cell activation
T41 244-259 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T42 561-570 http://purl.obolibrary.org/obo/GO_0051235 denotes retention

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T37 104-113 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T38 172-182 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T39 234-259 http://purl.obolibrary.org/obo/GO_0050869 denotes inhibit B‐cell activation
T40 242-259 http://purl.obolibrary.org/obo/GO_0042113 denotes B‐cell activation
T41 244-259 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T42 561-570 http://purl.obolibrary.org/obo/GO_0051235 denotes retention

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T107 0-67 Sentence denotes FcγRIIbs are the inhibitory‐type FcγR and arise from a single gene.
T108 68-149 Sentence denotes They lack intrinsic proinflammatory signaling and are instead immune checkpoints.
T109 150-280 Sentence denotes They provide feedback regulation by antibodies, in the form of immune complexes, to inhibit B‐cell activation by specific antigen.
T110 281-345 Sentence denotes They also control activating‐type FcγR function on innate cells.
T111 346-439 Sentence denotes Two major splice variant forms of FcγRIIb exist with differential tissue expression profiles.
T112 440-624 Sentence denotes FcγRIIb1 preferentially expressed on B lymphocytes contains a 20‐amino acid cytoplasmic insertion necessary for membrane retention and cocapping with the B‐cell antigen receptor (BCR).
T113 625-800 Sentence denotes FcγRIIb2 is the predominant inhibitory receptor found on basophils and neutrophils, as well as on subpopulations of mast cells, dendritic cells and some monocytes/macrophages.
T114 801-1017 Sentence denotes FcγRIIb2 lacks the cytoplasmic insertion of FcγRIIb1 and consequently can internalize rapidly including with the activating FcR when they are co‐cross‐linked.11 It is not clear which form is present on human T cells.