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PMC:7228307 / 10334-11233 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
189 350-354 Gene denotes FcγR Gene:2213
190 834-838 Gene denotes FcγR Gene:2213
191 612-616 Gene denotes FcγR Gene:2213
192 454-458 Gene denotes FcγR Gene:2213
193 121-125 Gene denotes FcγR Gene:2213
194 334-339 Species denotes human Tax:9606
195 606-611 Species denotes human Tax:9606

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T88 32-36 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T89 340-349 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T21 69-72 Disease denotes MOA http://purl.obolibrary.org/obo/MONDO_0016702

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T180 32-36 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T181 121-123 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T182 334-339 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T183 350-352 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T184 399-400 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T185 454-456 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T186 519-521 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T187 606-611 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T188 612-614 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T189 644-652 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primates
T190 654-660 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T191 824-833 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humanized
T192 834-836 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T49 43-51 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T50 236-244 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T51 379-387 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T52 675-683 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T65 32-36 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T66 52-64 http://purl.obolibrary.org/obo/BFO_0000034 denotes functions in
T67 340-349 http://purl.obolibrary.org/obo/CL_0000738 denotes leukocyte
T68 388-397 http://purl.obolibrary.org/obo/BFO_0000034 denotes functions
T69 684-692 http://purl.obolibrary.org/obo/BFO_0000034 denotes function

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
189 350-354 Gene denotes FcγR Gene:2213
190 834-838 Gene denotes FcγR Gene:2213
191 612-616 Gene denotes FcγR Gene:2213
192 454-458 Gene denotes FcγR Gene:2213
193 121-125 Gene denotes FcγR Gene:2213
194 334-339 Species denotes human Tax:9606
195 606-611 Species denotes human Tax:9606

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T8 334-339 Species denotes human NCBItxid:9606
T9 606-611 Species denotes human NCBItxid:9606
T10 624-631 Species denotes rodents NCBItxid:9989
T11 644-652 Species denotes primates NCBItxid:9443

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T57 0-255 Sentence denotes Understanding the importance of cell‐based effector functions in the MOA of therapeutic mAbs requires an appreciation of FcγR biology (Tables 1, 2, 3) which also underpins future efforts to tailor new mAbs for the exploitation‐specific effector responses.
T58 256-398 Sentence denotes In this review, we address only key aspects of the extensive knowledge of the human leukocyte FcγR family as it relates to effector functions.
T59 399-899 Sentence denotes A number of other reviews more comprehensively explore FcγR biology physiology, biochemistry, genetics and structure.7, 11, 12, 13, 14 Notwithstanding the recognized differences between the immunobiology of human FcγR and of rodents or nonhuman primates, animal models of FcR effector function in vivo have helped shape the strategies for the development of current therapeutic mAbs and are well reviewed.12, 15 Furthermore, humanized FcγR models will provide even greater insights into the future.16

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T87 32-36 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T88 340-349 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T57 0-255 Sentence denotes Understanding the importance of cell‐based effector functions in the MOA of therapeutic mAbs requires an appreciation of FcγR biology (Tables 1, 2, 3) which also underpins future efforts to tailor new mAbs for the exploitation‐specific effector responses.
T58 256-398 Sentence denotes In this review, we address only key aspects of the extensive knowledge of the human leukocyte FcγR family as it relates to effector functions.
T59 399-899 Sentence denotes A number of other reviews more comprehensively explore FcγR biology physiology, biochemistry, genetics and structure.7, 11, 12, 13, 14 Notwithstanding the recognized differences between the immunobiology of human FcγR and of rodents or nonhuman primates, animal models of FcR effector function in vivo have helped shape the strategies for the development of current therapeutic mAbs and are well reviewed.12, 15 Furthermore, humanized FcγR models will provide even greater insights into the future.16