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PMC:7228253 / 59-2797 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
22 64-111 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
23 113-123 Species denotes SARS‐CoV‐2 Tax:2697049
24 286-292 Species denotes people Tax:9606
25 802-812 Species denotes SARS‐CoV‐2 Tax:2697049
26 1015-1023 Species denotes patients Tax:9606
27 1083-1093 Species denotes SARS‐CoV‐2 Tax:2697049
28 1152-1160 Species denotes patients Tax:9606
29 1227-1237 Species denotes SARS‐CoV‐2 Tax:2697049
30 1548-1556 Species denotes patients Tax:9606
31 13-37 Disease denotes Coronavirus Disease 2019 MESH:C000657245
32 39-47 Disease denotes COVID‐19 MESH:C000657245
33 293-301 Disease denotes infected MESH:D007239
34 396-404 Disease denotes infected MESH:D007239
35 438-447 Disease denotes infection MESH:D007239
36 538-546 Disease denotes COVID‐19 MESH:C000657245
37 1006-1014 Disease denotes COVID‐19 MESH:C000657245
38 1029-1043 Disease denotes conjunctivitis MESH:D003231
39 1174-1188 Disease denotes conjunctivitis MESH:D003231
40 1439-1447 Disease denotes COVID‐19 MESH:C000657245
41 1539-1547 Disease denotes infected MESH:D007239
52 1767-1771 Gene denotes ACE2 Gene:59272
53 1917-1921 Gene denotes ACE2 Gene:59272
54 1643-1688 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
55 1690-1698 Species denotes SARS‐CoV Tax:694009
56 1718-1728 Species denotes SARS‐CoV‐2 Tax:2697049
57 1738-1743 Species denotes human Tax:9606
58 2041-2046 Species denotes human Tax:9606
59 2064-2082 Disease denotes corneal epithelium MESH:D003316
60 2521-2529 Disease denotes COVID‐19 MESH:C000657245
61 2659-2667 Disease denotes COVID‐19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T3 1110-1126 Body_part denotes conjunctival sac http://purl.org/sig/ont/fma/fma20291
T4 1260-1271 Body_part denotes conjunctiva http://purl.org/sig/ont/fma/fma59011
T5 1483-1486 Body_part denotes eye http://purl.org/sig/ont/fma/fma54448
T6 1788-1792 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T7 1834-1838 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T8 1839-1849 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T9 1872-1879 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T10 1955-1962 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T11 1970-1973 Body_part denotes eye http://purl.org/sig/ont/fma/fma54448
T12 1987-1993 Body_part denotes retina http://purl.org/sig/ont/fma/fma58301
T13 2002-2028 Body_part denotes retinal pigment epithelium http://purl.org/sig/ont/fma/fma58627
T14 2018-2028 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T15 2064-2082 Body_part denotes corneal epithelium http://purl.org/sig/ont/fma/fma58263
T16 2072-2082 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T17 2197-2202 Body_part denotes Tears http://purl.org/sig/ont/fma/fma59756
T18 2300-2305 Body_part denotes tears http://purl.org/sig/ont/fma/fma59756
T19 2351-2369 Body_part denotes nasolacrimal ducts http://purl.org/sig/ont/fma/fma9703
T20 2388-2405 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T21 2562-2565 Body_part denotes eye http://purl.org/sig/ont/fma/fma54448

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T3 1110-1126 Body_part denotes conjunctival sac http://purl.obolibrary.org/obo/UBERON_0005908
T4 1123-1126 Body_part denotes sac http://purl.obolibrary.org/obo/UBERON_0009856
T5 1260-1271 Body_part denotes conjunctiva http://purl.obolibrary.org/obo/UBERON_0001811
T6 1272-1275 Body_part denotes sac http://purl.obolibrary.org/obo/UBERON_0009856
T7 1483-1486 Body_part denotes eye http://purl.obolibrary.org/obo/UBERON_0000970
T8 1834-1849 Body_part denotes lung epithelium http://purl.obolibrary.org/obo/UBERON_0000115
T9 1834-1838 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T10 1839-1849 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T11 1970-1973 Body_part denotes eye http://purl.obolibrary.org/obo/UBERON_0000970
T12 1987-1993 Body_part denotes retina http://purl.obolibrary.org/obo/UBERON_0000966
T13 2018-2028 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T14 2064-2082 Body_part denotes corneal epithelium http://purl.obolibrary.org/obo/UBERON_0001772
T15 2072-2082 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T16 2178-2186 Body_part denotes lacrimal http://purl.obolibrary.org/obo/UBERON_3010146
T17 2233-2241 Body_part denotes lacrimal http://purl.obolibrary.org/obo/UBERON_3010146
T18 2351-2369 Body_part denotes nasolacrimal ducts http://purl.obolibrary.org/obo/UBERON_0002392
T19 2388-2405 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T20 2562-2565 Body_part denotes eye http://purl.obolibrary.org/obo/UBERON_0000970

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T2 13-37 Disease denotes Coronavirus Disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 39-47 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 64-111 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T5 64-97 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T6 113-117 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T7 438-447 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 538-546 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 802-806 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T10 1006-1014 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1029-1043 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T12 1083-1087 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T13 1174-1188 Disease denotes conjunctivitis http://purl.obolibrary.org/obo/MONDO_0003799
T14 1227-1231 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T15 1439-1447 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 1643-1676 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T17 1690-1694 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 1712-1716 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 1718-1722 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T20 2521-2529 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 2659-2667 Disease denotes COVID‐19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T3 169-172 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T4 208-211 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T5 311-314 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T6 514-517 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T7 711-712 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 779-780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 906-908 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T10 906-908 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T11 988-989 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 1075-1079 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T13 1123-1126 http://purl.obolibrary.org/obo/UBERON_0009856 denotes sac
T14 1206-1210 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T15 1260-1271 http://purl.obolibrary.org/obo/UBERON_0001811 denotes conjunctiva
T16 1260-1271 http://www.ebi.ac.uk/efo/EFO_0000374 denotes conjunctiva
T17 1272-1275 http://purl.obolibrary.org/obo/UBERON_0009856 denotes sac
T18 1483-1486 http://www.ebi.ac.uk/efo/EFO_0000827 denotes eye
T19 1558-1559 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 1738-1743 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T21 1786-1792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a cell
T22 1834-1849 http://purl.obolibrary.org/obo/UBERON_0000115 denotes lung epithelium
T23 1945-1954 http://purl.obolibrary.org/obo/UBERON_0001353 denotes posterior
T24 1970-1973 http://www.ebi.ac.uk/efo/EFO_0000827 denotes eye
T25 1975-1993 http://www.ebi.ac.uk/efo/EFO_0000832 denotes such as the retina
T26 2018-2028 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T27 2041-2046 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T28 2072-2082 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T29 2283-2288 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T30 2364-2369 http://purl.obolibrary.org/obo/UBERON_0000025 denotes ducts
T31 2364-2369 http://purl.obolibrary.org/obo/UBERON_0000058 denotes ducts
T32 2562-2565 http://www.ebi.ac.uk/efo/EFO_0000827 denotes eye

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 823-825 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T2 906-908 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T3 1094-1106 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T4 1102-1106 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T5 1238-1250 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T6 1246-1250 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T7 1744-1755 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T8 1763-1765 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T9 1872-1879 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T10 2002-2009 Chemical denotes retinal http://purl.obolibrary.org/obo/CHEBI_15035

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T2 0-7 Sentence denotes Editor,
T3 9-263 Sentence denotes The Coronavirus Disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is not only spreading throughout China but has reached more than 20 countries and has already posed threats to global health and economy.
T4 264-343 Sentence denotes So far, the number of people infected in China has climbed to more than 70 000.
T5 344-405 Sentence denotes Of them, at least 3019 healthcare workers have been infected.
T6 406-510 Sentence denotes However, the specific causes of infection among healthcare workers in hospital environments are unclear.
T7 511-622 Sentence denotes It has been confirmed that COVID‐19 is mainly transmitted through both respiratory droplets and direct contact.
T8 623-692 Sentence denotes Aerosols are another possible transmission route requiring attention.
T9 693-832 Sentence denotes In February 2020, a report in The Lancet raised the issue that ocular surfaces may be a potential target for SARS‐CoV‐2 invasion (Lu et al.
T10 833-839 Sentence denotes 2020).
T11 840-915 Sentence denotes However, two recent studies do not fully support this assumption (Li et al.
T12 916-933 Sentence denotes 2020; Zhou et al.
T13 934-959 Sentence denotes 2020, unpublished paper).
T14 960-1133 Sentence denotes The reason is that although a small number of COVID‐19 patients have conjunctivitis, not all of them show positive test of SARS‐CoV‐2 nucleic acid in conjunctival sac swabs.
T15 1134-1371 Sentence denotes In addition, some patients did not have conjunctivitis despite positive test results for the SARS‐CoV‐2 nucleic acid in their conjunctiva sac swabs (Dr. Yanping Song from Wuhan City, China, the outbreak area in China, unpublished paper).
T16 1372-1614 Sentence denotes Interestingly, the medical history of the clinical physicians with COVID‐19 revealed that neither of them used eye goggles when examining (physician 1) and intubating infected patients (a high‐risk procedure to produce aerosol) (physician 2).
T17 1615-1907 Sentence denotes Studies show that, like the severe acute respiratory syndrome coronavirus (SARS‐CoV) that caused SARS, SARS‐CoV‐2 binds to human angiotensin‐enzyme II (ACE2), using it as a cell entry receptor to invade respiratory and lung epithelium through the spike (S) protein (Zhou et al., 2020a,2020b).
T18 1908-2100 Sentence denotes However, ACE2 is mainly expressed in posterior tissues of the eye, such as the retina and the retinal pigment epithelium, not in the human conjunctival and corneal epithelium (Choudhary et al.
T19 2101-2107 Sentence denotes 2017).
T20 2108-2196 Sentence denotes We presume that these previous studies ignored the characteristics of lacrimal drainage.
T21 2197-2249 Sentence denotes Tears are constantly renewed by the lacrimal system.
T22 2250-2406 Sentence denotes Therefore, we speculate that the virus enters the tears through droplets, which may pass through the nasolacrimal ducts and then into the respiratory tract.
T23 2407-2581 Sentence denotes Combined with all this information, we assert that, when coming into contact with confirmed or suspected cases of COVID‐19, healthcare workers should wear eye safety goggles.
T24 2582-2668 Sentence denotes This should become one of the critical measures for preventing the spread of COVID‐19.
T25 2669-2738 Sentence denotes The authors hope this topic is helpful for work in the outbreak area.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1029-1043 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509
T2 1174-1188 Phenotype denotes conjunctivitis http://purl.obolibrary.org/obo/HP_0000509