PMC:7225588 / 27753-28802 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7225588","sourcedb":"PMC","sourceid":"7225588","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7225588","text":"Metabolic pathway and enrichment analyses revealed six biochemical pathways altered following exposure to lower temperature suggesting theses pathways were essential in combating the stress. Most of these metabolic pathways were involved in the energy production. The most affected metabolic pathway was citric acid cycle; this may suggest the lower energy production by cells exposed stress to minimize the energy during the stressful conditions. The substantial alteration in purine and pyrimidine pathways was represented by the significant reduction in their metabolites. The reductions in these metabolites may indicate the consumption of these metabolites to produce proteins to combat the cold stress. Our prior investigation showed that cold stress led to significant increase in nine ribosomal proteins and a substantial decrease in the majority of amino acids (Alreshidi et al., 2015). An earlier study showed that, the abundance of nucleotides was reduced ten-folds in lactic bacteria when grown in lactose medium (Kilstrup et al., 2005).","tracks":[{"project":"2_test","denotations":[{"id":"32457719-25782752-35703036","span":{"begin":889,"end":893},"obj":"25782752"},{"id":"32457719-15935511-35703037","span":{"begin":1043,"end":1047},"obj":"15935511"}],"attributes":[{"subj":"32457719-25782752-35703036","pred":"source","obj":"2_test"},{"subj":"32457719-15935511-35703037","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#a893ec","default":true}]}]}}