PMC:7224584 / 9232-9814 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7224584","sourcedb":"PMC","sourceid":"7224584","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7224584","text":"The excretion of light chains causes tubular damage, generating obstructive nephropathy known as \"myeloma kidney.\" This nephropathy is characterized by three main components: proximal renal tubular atrophy, the formation of eosinophilic cylinders in the distal tubule, and inflammation with interstitial fibrosis [5]. The typical histopathological finding is the presence of light chain eosinophilic cylinders inside the lumen of the renal tubules surrounded by cells - multinucleated giants generating a \"foreign body\" reaction in the distal tubules and collecting duct (Figure 6).","tracks":[{"project":"2_test","denotations":[{"id":"32419992-28545410-23905630","span":{"begin":314,"end":315},"obj":"28545410"}],"attributes":[{"subj":"32419992-28545410-23905630","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ec93bf","default":true}]}]}}