PMC:7219429 / 6012-6415 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T64","span":{"begin":59,"end":61},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T65","span":{"begin":399,"end":401},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"}],"text":"Azithromycin (ATM) is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one. The 3D structure of ATM was obtained from pdb file # 5UXD (ATM co-crystallized with macrolide 2′-phosphotransferase) [22]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T85","span":{"begin":14,"end":17},"obj":"Chemical"},{"id":"T86","span":{"begin":97,"end":104},"obj":"Chemical"},{"id":"T87","span":{"begin":123,"end":126},"obj":"Chemical"},{"id":"T88","span":{"begin":129,"end":134},"obj":"Chemical"},{"id":"T90","span":{"begin":173,"end":180},"obj":"Chemical"},{"id":"T91","span":{"begin":183,"end":190},"obj":"Chemical"},{"id":"T93","span":{"begin":213,"end":216},"obj":"Chemical"},{"id":"T94","span":{"begin":301,"end":304},"obj":"Chemical"},{"id":"T95","span":{"begin":340,"end":343},"obj":"Chemical"},{"id":"T96","span":{"begin":365,"end":374},"obj":"Chemical"}],"attributes":[{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_29354"},{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_37807"},{"id":"A89","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_62801"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A91","pred":"chebi_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/CHEBI_32772"},{"id":"A92","pred":"chebi_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/CHEBI_44520"},{"id":"A93","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_29354"},{"id":"A94","pred":"chebi_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A95","pred":"chebi_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A96","pred":"chebi_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/CHEBI_25106"}],"text":"Azithromycin (ATM) is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one. The 3D structure of ATM was obtained from pdb file # 5UXD (ATM co-crystallized with macrolide 2′-phosphotransferase) [22]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T49","span":{"begin":0,"end":280},"obj":"Sentence"},{"id":"T50","span":{"begin":281,"end":403},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Azithromycin (ATM) is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one. The 3D structure of ATM was obtained from pdb file # 5UXD (ATM co-crystallized with macrolide 2′-phosphotransferase) [22]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"212","span":{"begin":323,"end":326},"obj":"Gene"},{"id":"213","span":{"begin":365,"end":374},"obj":"Chemical"}],"attributes":[{"id":"A212","pred":"tao:has_database_id","subj":"212","obj":"Gene:5131"},{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"MESH:D018942"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Azithromycin (ATM) is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one. The 3D structure of ATM was obtained from pdb file # 5UXD (ATM co-crystallized with macrolide 2′-phosphotransferase) [22]."}