PMC:7219429 / 2427-3636
Annnotations
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T13 | 38-54 | Disease | denotes | SARS-coronavirus | http://purl.obolibrary.org/obo/MONDO_0005091 |
T14 | 58-66 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 146-154 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T16 | 636-644 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 874-883 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T18 | 1200-1208 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T26 | 70-73 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T27 | 81-82 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T28 | 169-170 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T29 | 212-213 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T30 | 303-304 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T31 | 432-435 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T32 | 515-516 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T33 | 556-561 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2], a |
T34 | 618-619 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T35 | 659-660 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T36 | 751-752 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T37 | 840-843 | http://purl.obolibrary.org/obo/PR_000001343 | denotes | aim |
T38 | 1173-1174 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T42 | 345-357 | Chemical | denotes | antimalarial | http://purl.obolibrary.org/obo/CHEBI_38068 |
T43 | 358-362 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T44 | 364-382 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T45 | 401-411 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
T46 | 413-425 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
T47 | 427-430 | Chemical | denotes | ATM | http://purl.obolibrary.org/obo/CHEBI_2955 |
T48 | 537-548 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T49 | 797-802 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
T50 | 937-940 | Chemical | denotes | ATM | http://purl.obolibrary.org/obo/CHEBI_2955 |
T51 | 1108-1111 | Chemical | denotes | ATM | http://purl.obolibrary.org/obo/CHEBI_2955 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24 | 0-160 | Sentence | denotes | The emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) has led to a global pandemic disease referred to as coronavirus disease 19 (COVID-19) [1]. |
T25 | 161-241 | Sentence | denotes | In such a health emergency, it is critical to find a cure and stop the pandemic. |
T26 | 242-466 | Sentence | denotes | Among the potential solutions currently under investigation, a combination bitherapy consisting of the antimalarial drug, hydroxychloroquine (CLQ-OH) with the antibiotic, azithromycin (ATM) has received particular attention. |
T27 | 467-658 | Sentence | denotes | Following initial reports from China indicating a potential effect of chloroquine (CLQ) [2], a preliminary clinical trial was implemented in France on a small cohort of COVID-19 patients [3]. |
T28 | 659-830 | Sentence | denotes | A significant viral load reduction was observed in the 20 patients treated with CLQ-OH [3], a CLQ derivative with increased solubility in water and decreased toxicity [4]. |
T29 | 831-952 | Sentence | denotes | With the aim of preventing bacterial super-infection, six additional patients in this trial also received ATM for 5 days. |
T30 | 953-1017 | Sentence | denotes | All these patients had undetectable viral load after 6 days [3]. |
T31 | 1018-1209 | Sentence | denotes | Thus, although these promising data need clinical confirmation with more patients, CLQ-OH/ATM combination therapy already appears superior to CLQ alone as a first-line treatment for COVID-19. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
112 | 38-56 | Species | denotes | SARS-coronavirus 2 | Tax:2697049 |
113 | 58-68 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
114 | 645-653 | Species | denotes | patients | Tax:9606 |
115 | 717-725 | Species | denotes | patients | Tax:9606 |
116 | 900-908 | Species | denotes | patients | Tax:9606 |
117 | 963-971 | Species | denotes | patients | Tax:9606 |
118 | 1091-1099 | Species | denotes | patients | Tax:9606 |
119 | 364-382 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
120 | 384-390 | Chemical | denotes | CLQ-OH | |
121 | 413-425 | Chemical | denotes | azithromycin | MESH:D017963 |
122 | 427-430 | Chemical | denotes | ATM | MESH:D017963 |
123 | 537-548 | Chemical | denotes | chloroquine | MESH:D002738 |
124 | 550-553 | Chemical | denotes | CLQ | MESH:D002738 |
125 | 739-745 | Chemical | denotes | CLQ-OH | |
126 | 753-756 | Chemical | denotes | CLQ | MESH:D002738 |
127 | 797-802 | Chemical | denotes | water | MESH:D014867 |
128 | 1101-1107 | Chemical | denotes | CLQ-OH | |
129 | 1160-1163 | Chemical | denotes | CLQ | MESH:D002738 |
130 | 122-144 | Disease | denotes | coronavirus disease 19 | MESH:C000657245 |
131 | 146-154 | Disease | denotes | COVID-19 | MESH:C000657245 |
132 | 636-644 | Disease | denotes | COVID-19 | MESH:C000657245 |
133 | 807-825 | Disease | denotes | decreased toxicity | MESH:D066126 |
134 | 858-883 | Disease | denotes | bacterial super-infection | MESH:D001424 |
135 | 1200-1208 | Disease | denotes | COVID-19 | MESH:C000657245 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32405156-32015508-48150994 | 157-158 | 32015508 | denotes | 1 |
32405156-32074550-48150995 | 556-557 | 32074550 | denotes | 2 |
32405156-32194981-48150996 | 827-828 | 32194981 | denotes | 4 |
T92857 | 157-158 | 32015508 | denotes | 1 |
T20596 | 556-557 | 32074550 | denotes | 2 |
T63350 | 827-828 | 32194981 | denotes | 4 |