PMC:7219429 / 21-479 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":372,"end":383},"obj":"Body_part"},{"id":"T2","span":{"begin":384,"end":389},"obj":"Body_part"},{"id":"T3","span":{"begin":443,"end":450},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":70,"end":78},"obj":"Disease"},{"id":"T2","span":{"begin":197,"end":205},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":117,"end":122},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T2","span":{"begin":208,"end":211},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T3","span":{"begin":219,"end":220},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":319,"end":325},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T5","span":{"begin":431,"end":436},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":11,"end":29},"obj":"Chemical"},{"id":"T3","span":{"begin":34,"end":46},"obj":"Chemical"},{"id":"T4","span":{"begin":267,"end":279},"obj":"Chemical"},{"id":"T5","span":{"begin":355,"end":367},"obj":"Chemical"},{"id":"T6","span":{"begin":372,"end":383},"obj":"Chemical"},{"id":"T7","span":{"begin":443,"end":450},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":117,"end":140},"obj":"http://purl.obolibrary.org/obo/GO_0019048"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":82,"end":147},"obj":"Sentence"},{"id":"T3","span":{"begin":149,"end":159},"obj":"Sentence"},{"id":"T4","span":{"begin":160,"end":244},"obj":"Sentence"},{"id":"T5","span":{"begin":245,"end":325},"obj":"Sentence"},{"id":"T6","span":{"begin":326,"end":401},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}

{"project":"LitCovid-PubTator","denotations":[{"id":"3","span":{"begin":70,"end":80},"obj":"Species"},{"id":"4","span":{"begin":11,"end":29},"obj":"Chemical"},{"id":"5","span":{"begin":34,"end":46},"obj":"Chemical"},{"id":"8","span":{"begin":180,"end":195},"obj":"Species"},{"id":"9","span":{"begin":197,"end":207},"obj":"Species"},{"id":"12","span":{"begin":248,"end":266},"obj":"Chemical"},{"id":"13","span":{"begin":267,"end":279},"obj":"Chemical"},{"id":"16","span":{"begin":355,"end":367},"obj":"Chemical"},{"id":"17","span":{"begin":372,"end":389},"obj":"Chemical"},{"id":"23","span":{"begin":437,"end":442},"obj":"Gene"},{"id":"25","span":{"begin":405,"end":417},"obj":"Chemical"}],"attributes":[{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"Tax:2697049"},{"id":"A4","pred":"tao:has_database_id","subj":"4","obj":"MESH:D006886"},{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"MESH:D017963"},{"id":"A8","pred":"tao:has_database_id","subj":"8","obj":"Tax:2697049"},{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"Tax:2697049"},{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"MESH:D006886"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"MESH:D017963"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"MESH:D017963"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"Gene:43740568"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:D017963"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS"}