PMC:7219429 / 17095-17583 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T93","span":{"begin":31,"end":38},"obj":"Body_part"},{"id":"T94","span":{"begin":93,"end":103},"obj":"Body_part"},{"id":"T95","span":{"begin":310,"end":315},"obj":"Body_part"},{"id":"T96","span":{"begin":321,"end":336},"obj":"Body_part"},{"id":"T97","span":{"begin":378,"end":388},"obj":"Body_part"},{"id":"T98","span":{"begin":429,"end":433},"obj":"Body_part"}],"attributes":[{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma12520"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T168","span":{"begin":93,"end":111},"obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"T169","span":{"begin":93,"end":111},"obj":"http://purl.obolibrary.org/obo/PR_000036907"},{"id":"T170","span":{"begin":143,"end":145},"obj":"http://purl.obolibrary.org/obo/CLO_0007622"},{"id":"T171","span":{"begin":308,"end":309},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T172","span":{"begin":321,"end":327},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T173","span":{"begin":328,"end":336},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T174","span":{"begin":369,"end":370},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T175","span":{"begin":378,"end":396},"obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"T176","span":{"begin":378,"end":396},"obj":"http://purl.obolibrary.org/obo/PR_000036907"},{"id":"T177","span":{"begin":485,"end":487},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T285","span":{"begin":31,"end":38},"obj":"Chemical"},{"id":"T286","span":{"begin":39,"end":42},"obj":"Chemical"},{"id":"T287","span":{"begin":53,"end":56},"obj":"Chemical"},{"id":"T290","span":{"begin":93,"end":111},"obj":"Chemical"},{"id":"T291","span":{"begin":93,"end":103},"obj":"Chemical"},{"id":"T292","span":{"begin":93,"end":98},"obj":"Chemical"},{"id":"T293","span":{"begin":99,"end":103},"obj":"Chemical"},{"id":"T294","span":{"begin":122,"end":124},"obj":"Chemical"},{"id":"T295","span":{"begin":143,"end":145},"obj":"Chemical"},{"id":"T296","span":{"begin":224,"end":227},"obj":"Chemical"},{"id":"T299","span":{"begin":269,"end":282},"obj":"Chemical"},{"id":"T301","span":{"begin":287,"end":298},"obj":"Chemical"},{"id":"T302","span":{"begin":310,"end":315},"obj":"Chemical"},{"id":"T303","span":{"begin":378,"end":396},"obj":"Chemical"},{"id":"T304","span":{"begin":378,"end":388},"obj":"Chemical"},{"id":"T305","span":{"begin":378,"end":383},"obj":"Chemical"},{"id":"T306","span":{"begin":384,"end":388},"obj":"Chemical"}],"attributes":[{"id":"A285","pred":"chebi_id","subj":"T285","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A286","pred":"chebi_id","subj":"T286","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A287","pred":"chebi_id","subj":"T287","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A288","pred":"chebi_id","subj":"T287","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A289","pred":"chebi_id","subj":"T287","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A290","pred":"chebi_id","subj":"T290","obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"A291","pred":"chebi_id","subj":"T291","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A292","pred":"chebi_id","subj":"T292","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A293","pred":"chebi_id","subj":"T293","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A294","pred":"chebi_id","subj":"T294","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"id":"A295","pred":"chebi_id","subj":"T295","obj":"http://purl.obolibrary.org/obo/CHEBI_74699"},{"id":"A296","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A297","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A298","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_17636"},{"id":"A300","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_64583"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A306","pred":"chebi_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T16","span":{"begin":53,"end":56},"obj":"GlycoEpitope"},{"id":"T17","span":{"begin":224,"end":227},"obj":"GlycoEpitope"}],"attributes":[{"id":"A16","pred":"glyco_epitope_db_id","subj":"T16","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A17","pred":"glyco_epitope_db_id","subj":"T17","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}

{"project":"LitCovid-sentences","denotations":[{"id":"T127","span":{"begin":68,"end":208},"obj":"Sentence"},{"id":"T128","span":{"begin":209,"end":344},"obj":"Sentence"},{"id":"T129","span":{"begin":345,"end":434},"obj":"Sentence"},{"id":"T130","span":{"begin":435,"end":488},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}

{"project":"LitCovid-PubTator","denotations":[{"id":"414","span":{"begin":25,"end":30},"obj":"Gene"},{"id":"415","span":{"begin":47,"end":52},"obj":"Gene"},{"id":"416","span":{"begin":224,"end":227},"obj":"Chemical"},{"id":"417","span":{"begin":269,"end":282},"obj":"Chemical"},{"id":"418","span":{"begin":287,"end":298},"obj":"Chemical"},{"id":"419","span":{"begin":310,"end":315},"obj":"Chemical"}],"attributes":[{"id":"A414","pred":"tao:has_database_id","subj":"414","obj":"Gene:43740568"},{"id":"A415","pred":"tao:has_database_id","subj":"415","obj":"Gene:43740568"},{"id":"A416","pred":"tao:has_database_id","subj":"416","obj":"MESH:D005677"},{"id":"A417","pred":"tao:has_database_id","subj":"417","obj":"MESH:D013109"},{"id":"A418","pred":"tao:has_database_id","subj":"418","obj":"MESH:D002784"},{"id":"A419","pred":"tao:has_database_id","subj":"419","obj":"MESH:D008055"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Energy of interaction of spike protein-ATM and spike-GM1 complexes. Results are expressed by amino acid residue as mean ± SD of three distinct MD simulations (50 ns) with the same starting docking conditions. In the case of GM1, the simulations are done in presence of sphingomyelin and cholesterol to mimic a lipid raft plasma membrane domain. Each bar corresponds to a single amino acid residue, as indicated in the horizontal axis. Detailed values and statistics are shown in Table S1."}