PMC:7219429 / 170-618 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":223,"end":234},"obj":"Body_part"},{"id":"T2","span":{"begin":235,"end":240},"obj":"Body_part"},{"id":"T3","span":{"begin":294,"end":301},"obj":"Body_part"},{"id":"T4","span":{"begin":348,"end":360},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma82816"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T2","span":{"begin":48,"end":56},"obj":"Disease"},{"id":"T3","span":{"begin":305,"end":313},"obj":"Disease"},{"id":"T4","span":{"begin":428,"end":436},"obj":"Disease"},{"id":"T5","span":{"begin":439,"end":448},"obj":"Disease"}],"attributes":[{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T2","span":{"begin":59,"end":62},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T3","span":{"begin":70,"end":71},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":170,"end":176},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T5","span":{"begin":282,"end":287},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":118,"end":130},"obj":"Chemical"},{"id":"T5","span":{"begin":206,"end":218},"obj":"Chemical"},{"id":"T6","span":{"begin":223,"end":234},"obj":"Chemical"},{"id":"T7","span":{"begin":294,"end":301},"obj":"Chemical"},{"id":"T8","span":{"begin":320,"end":338},"obj":"Chemical"},{"id":"T9","span":{"begin":348,"end":360},"obj":"Chemical"},{"id":"T10","span":{"begin":383,"end":395},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}

{"project":"LitCovid-sentences","denotations":[{"id":"T3","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T4","span":{"begin":11,"end":95},"obj":"Sentence"},{"id":"T5","span":{"begin":96,"end":176},"obj":"Sentence"},{"id":"T6","span":{"begin":177,"end":252},"obj":"Sentence"},{"id":"T7","span":{"begin":253,"end":360},"obj":"Sentence"},{"id":"T8","span":{"begin":361,"end":448},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}

{"project":"LitCovid-PubTator","denotations":[{"id":"8","span":{"begin":31,"end":46},"obj":"Species"},{"id":"9","span":{"begin":48,"end":58},"obj":"Species"},{"id":"12","span":{"begin":99,"end":117},"obj":"Chemical"},{"id":"13","span":{"begin":118,"end":130},"obj":"Chemical"},{"id":"16","span":{"begin":206,"end":218},"obj":"Chemical"},{"id":"17","span":{"begin":223,"end":240},"obj":"Chemical"},{"id":"23","span":{"begin":288,"end":293},"obj":"Gene"},{"id":"24","span":{"begin":305,"end":315},"obj":"Species"},{"id":"25","span":{"begin":256,"end":268},"obj":"Chemical"},{"id":"26","span":{"begin":320,"end":338},"obj":"Chemical"},{"id":"27","span":{"begin":348,"end":360},"obj":"Chemical"},{"id":"31","span":{"begin":364,"end":382},"obj":"Chemical"},{"id":"32","span":{"begin":383,"end":395},"obj":"Chemical"},{"id":"33","span":{"begin":428,"end":448},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"tao:has_database_id","subj":"8","obj":"Tax:2697049"},{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"Tax:2697049"},{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"MESH:D006886"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"MESH:D017963"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"MESH:D017963"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"Gene:43740568"},{"id":"A24","pred":"tao:has_database_id","subj":"24","obj":"Tax:2697049"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:D017963"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"MESH:D006886"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"MESH:D005732"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"MESH:D006886"},{"id":"A32","pred":"tao:has_database_id","subj":"32","obj":"MESH:D017963"},{"id":"A33","pred":"tao:has_database_id","subj":"33","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Highlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus spike protein of SARS-CoV-2 and hydroxychloroquine binds to gangliosides\n• Hydroxychloroquine/azithromycin have synergistic effect against SARS-CoV-2 infection"}