PMC:7219429 / 0-458 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":393,"end":404},"obj":"Body_part"},{"id":"T2","span":{"begin":405,"end":410},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma82737"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":91,"end":99},"obj":"Disease"},{"id":"T2","span":{"begin":218,"end":226},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":138,"end":143},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T2","span":{"begin":229,"end":232},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T3","span":{"begin":240,"end":241},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":340,"end":346},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T5","span":{"begin":452,"end":457},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":12,"end":21},"obj":"Chemical"},{"id":"T2","span":{"begin":32,"end":50},"obj":"Chemical"},{"id":"T3","span":{"begin":55,"end":67},"obj":"Chemical"},{"id":"T4","span":{"begin":288,"end":300},"obj":"Chemical"},{"id":"T5","span":{"begin":376,"end":388},"obj":"Chemical"},{"id":"T6","span":{"begin":393,"end":404},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":138,"end":161},"obj":"http://purl.obolibrary.org/obo/GO_0019048"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":102},"obj":"Sentence"},{"id":"T2","span":{"begin":103,"end":168},"obj":"Sentence"},{"id":"T3","span":{"begin":170,"end":180},"obj":"Sentence"},{"id":"T4","span":{"begin":181,"end":265},"obj":"Sentence"},{"id":"T5","span":{"begin":266,"end":346},"obj":"Sentence"},{"id":"T6","span":{"begin":347,"end":422},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}

{"project":"LitCovid-PubTator","denotations":[{"id":"3","span":{"begin":91,"end":101},"obj":"Species"},{"id":"4","span":{"begin":32,"end":50},"obj":"Chemical"},{"id":"5","span":{"begin":55,"end":67},"obj":"Chemical"},{"id":"8","span":{"begin":201,"end":216},"obj":"Species"},{"id":"9","span":{"begin":218,"end":228},"obj":"Species"},{"id":"12","span":{"begin":269,"end":287},"obj":"Chemical"},{"id":"13","span":{"begin":288,"end":300},"obj":"Chemical"},{"id":"16","span":{"begin":376,"end":388},"obj":"Chemical"},{"id":"17","span":{"begin":393,"end":410},"obj":"Chemical"},{"id":"25","span":{"begin":426,"end":438},"obj":"Chemical"}],"attributes":[{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"Tax:2697049"},{"id":"A4","pred":"tao:has_database_id","subj":"4","obj":"MESH:D006886"},{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"MESH:D017963"},{"id":"A8","pred":"tao:has_database_id","subj":"8","obj":"Tax:2697049"},{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"Tax:2697049"},{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"MESH:D006886"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"MESH:D017963"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"MESH:D017963"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:D017963"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal\n\nHighlights\n• Emergence of the new coronavirus, SARS-CoV-2 has led to a global pandemic disease\n• Hydroxychloroquine/azithromycin combination therapy is currently being tested\n• Molecular mimicry between azithromycin and ganglioside sugar is revealed\n• Azithromycin binds to the virus "}