PMC:7216762 / 9312-10910 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T10","span":{"begin":381,"end":398},"obj":"Body_part"},{"id":"T11","span":{"begin":574,"end":587},"obj":"Body_part"},{"id":"T12","span":{"begin":806,"end":809},"obj":"Body_part"},{"id":"T13","span":{"begin":1223,"end":1228},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma265130"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma9825"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T7","span":{"begin":381,"end":398},"obj":"Body_part"},{"id":"T8","span":{"begin":574,"end":587},"obj":"Body_part"},{"id":"T9","span":{"begin":1223,"end":1228},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0002405"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T29","span":{"begin":1031,"end":1041},"obj":"Disease"}],"attributes":[{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T52","span":{"begin":147,"end":148},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T53","span":{"begin":176,"end":177},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T54","span":{"begin":262,"end":267},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T55","span":{"begin":349,"end":355},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T56","span":{"begin":407,"end":412},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T57","span":{"begin":492,"end":497},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T58","span":{"begin":574,"end":587},"obj":"http://purl.obolibrary.org/obo/UBERON_0002405"},{"id":"T59","span":{"begin":600,"end":601},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T60","span":{"begin":665,"end":666},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T61","span":{"begin":1156,"end":1159},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T62","span":{"begin":1223,"end":1228},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T63","span":{"begin":1223,"end":1228},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T64","span":{"begin":1475,"end":1478},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T3","span":{"begin":298,"end":304},"obj":"http://purl.obolibrary.org/obo/GO_0007613"},{"id":"T4","span":{"begin":612,"end":627},"obj":"http://purl.obolibrary.org/obo/GO_0006955"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-sentences","denotations":[{"id":"T63","span":{"begin":0,"end":132},"obj":"Sentence"},{"id":"T64","span":{"begin":133,"end":316},"obj":"Sentence"},{"id":"T65","span":{"begin":317,"end":420},"obj":"Sentence"},{"id":"T66","span":{"begin":421,"end":739},"obj":"Sentence"},{"id":"T67","span":{"begin":740,"end":791},"obj":"Sentence"},{"id":"T68","span":{"begin":792,"end":1042},"obj":"Sentence"},{"id":"T69","span":{"begin":1043,"end":1243},"obj":"Sentence"},{"id":"T70","span":{"begin":1244,"end":1380},"obj":"Sentence"},{"id":"T71","span":{"begin":1381,"end":1598},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}

{"project":"LitCovid-PubTator","denotations":[{"id":"99","span":{"begin":207,"end":213},"obj":"Species"},{"id":"100","span":{"begin":1292,"end":1298},"obj":"Species"},{"id":"101","span":{"begin":1031,"end":1041},"obj":"Disease"}],"attributes":[{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"Tax:9606"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"Tax:9606"},{"id":"A101","pred":"tao:has_database_id","subj":"101","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This is the fundamental question that two colleagues of the University of Milan, Prof. Bollati and Dr. Milani, are trying to answer. They designed a study to determine whether a large cohort of asymptomatic people already have circulating antibodies against the virus, both short-term response and memory antibodies. In parallel, volunteers will be tested for the presence, in the respiratory tract, of the virus itself. This will lead, in the first place, to an understanding of whether the virus had been circulating long before the outbreak of the epidemic (allowing the immune system to generate a long-term immune response in some individuals) and, second, to a cross-checking of the results of swabs and detection of false negatives. The results will need to be interpreted cautiously. Indeed, viral RNA quantification is an established diagnostic tool, but the interpretation of the presence of specific antibodies is still under debate, as it is currently unknown whether they will confer long-term immunity against future infections. The protocol for safe sample collection (timing of individual appointments and access to the dedicated location) has been designed in collaboration with the Italian Association of Blood Donors (AVIS). The call for voluntary participation to all the people working at the university registered more than 1500 volunteers in less than 24 h. The study, named UNICORN (UNIversity against CORoNavirus), funded by the University of Milan, has already obtained ethics committee approval and is ready to start as soon as citizens’ mobility restrictions are lifted."}