
PMC:7214333
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 345-350 | Body_part | denotes | bowel | http://purl.org/sig/ont/fma/fma7199 |
T2 | 391-401 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T3 | 552-562 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T4 | 786-791 | Body_part | denotes | bowel | http://purl.org/sig/ont/fma/fma7199 |
T5 | 967-974 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T6 | 987-992 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T7 | 1063-1069 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
T8 | 1096-1111 | Body_part | denotes | small intestine | http://purl.org/sig/ont/fma/fma7200 |
T9 | 1124-1140 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T10 | 1135-1140 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T11 | 1179-1183 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T12 | 1223-1228 | Body_part | denotes | bowel | http://purl.org/sig/ont/fma/fma7199 |
T13 | 1616-1622 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
T14 | 1767-1781 | Body_part | denotes | terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T15 | 1831-1836 | Body_part | denotes | colon | http://purl.org/sig/ont/fma/fma14543 |
T16 | 1917-1923 | Body_part | denotes | rectum | http://purl.org/sig/ont/fma/fma14544 |
T17 | 1982-1996 | Body_part | denotes | terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T18 | 2069-2076 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T19 | 2328-2342 | Body_part | denotes | terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T20 | 2355-2361 | Body_part | denotes | rectum | http://purl.org/sig/ont/fma/fma14544 |
T21 | 2464-2470 | Body_part | denotes | rectum | http://purl.org/sig/ont/fma/fma14544 |
T22 | 2475-2489 | Body_part | denotes | terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T23 | 2555-2559 | Body_part | denotes | mRNA | http://purl.org/sig/ont/fma/fma67122 |
T24 | 2567-2581 | Body_part | denotes | terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T25 | 2586-2592 | Body_part | denotes | rectum | http://purl.org/sig/ont/fma/fma14544 |
T26 | 2772-2786 | Body_part | denotes | Terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
T27 | 2790-2796 | Body_part | denotes | Rectum | http://purl.org/sig/ont/fma/fma14544 |
T28 | 2836-2842 | Body_part | denotes | Rectum | http://purl.org/sig/ont/fma/fma14544 |
T29 | 2883-2897 | Body_part | denotes | Terminal ileum | http://purl.org/sig/ont/fma/fma14966 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
4 | 25-33 | Species | denotes | patients | Tax:9606 |
5 | 0-17 | Disease | denotes | Excessive anxiety | MESH:D001007 |
6 | 21-24 | Disease | denotes | IBD | MESH:D015212 |
7 | 53-61 | Disease | denotes | COVID-19 | MESH:C000657245 |
26 | 89-111 | Species | denotes | 2019 novel coronavirus | Tax:2697049 |
27 | 265-275 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
28 | 489-497 | Species | denotes | patients | Tax:9606 |
29 | 726-734 | Species | denotes | patients | Tax:9606 |
30 | 113-134 | Disease | denotes | SARS-CoV-2) infection | MESH:C000657245 |
31 | 144-152 | Disease | denotes | COVID-19 | MESH:C000657245 |
32 | 308-315 | Disease | denotes | anxiety | MESH:D001007 |
33 | 332-358 | Disease | denotes | Inflammatory bowel disease | MESH:D015212 |
34 | 360-363 | Disease | denotes | IBD | MESH:D015212 |
35 | 391-409 | Disease | denotes | intestinal disease | MESH:D007410 |
36 | 421-439 | Disease | denotes | ulcerative colitis | MESH:D003093 |
37 | 449-464 | Disease | denotes | Crohn's disease | MESH:D003424 |
38 | 503-510 | Disease | denotes | anxiety | MESH:D001007 |
39 | 520-527 | Disease | denotes | anxiety | MESH:D001007 |
40 | 552-571 | Disease | denotes | intestinal diseases | MESH:D007410 |
41 | 626-634 | Disease | denotes | COVID-19 | MESH:C000657245 |
42 | 655-662 | Disease | denotes | anxiety | MESH:D001007 |
43 | 722-725 | Disease | denotes | IBD | MESH:D015212 |
57 | 961-965 | Gene | denotes | ACE2 | Gene:59272 |
58 | 1073-1080 | Gene | denotes | TMPRSS2 | Gene:7113 |
59 | 1142-1146 | Gene | denotes | ACE2 | Gene:59272 |
60 | 879-887 | Species | denotes | patients | Tax:9606 |
61 | 903-914 | Species | denotes | coronavirus | Tax:11118 |
62 | 1090-1095 | Species | denotes | human | Tax:9606 |
63 | 1232-1240 | Species | denotes | patients | Tax:9606 |
64 | 1063-1069 | Chemical | denotes | serine | MESH:D012694 |
65 | 863-871 | Disease | denotes | COVID-19 | MESH:C000657245 |
66 | 875-878 | Disease | denotes | IBD | MESH:D015212 |
67 | 1005-1013 | Disease | denotes | COVID-19 | MESH:C000657245 |
68 | 1116-1123 | Disease | denotes | colonic | MESH:D003110 |
69 | 1246-1254 | Disease | denotes | COVID-19 | MESH:C000657245 |
75 | 2711-2715 | Gene | denotes | ACE2 | Gene:59272 |
76 | 2716-2723 | Gene | denotes | TMPRSS2 | Gene:7113 |
77 | 2768-2771 | Disease | denotes | IBD | MESH:D015212 |
78 | 2832-2835 | Disease | denotes | IBD | MESH:D015212 |
79 | 2879-2882 | Disease | denotes | IBD | MESH:D015212 |
85 | 2538-2542 | Gene | denotes | ACE2 | Gene:59272 |
86 | 2547-2554 | Gene | denotes | TMPRSS2 | Gene:7113 |
87 | 2600-2608 | Species | denotes | patients | Tax:9606 |
88 | 2596-2599 | Disease | denotes | IBD | MESH:D015212 |
89 | 2627-2630 | Disease | denotes | IBD | MESH:D015212 |
114 | 1755-1759 | Gene | denotes | ACE2 | Gene:59272 |
115 | 1902-1906 | Gene | denotes | ACE2 | Gene:59272 |
116 | 2004-2008 | Gene | denotes | ACE2 | Gene:59272 |
117 | 2084-2088 | Gene | denotes | ACE2 | Gene:59272 |
118 | 2202-2206 | Gene | denotes | ACE2 | Gene:59272 |
119 | 2293-2300 | Gene | denotes | TMPRSS2 | Gene:7113 |
120 | 2438-2445 | Gene | denotes | TMPRSS2 | Gene:7113 |
121 | 1327-1335 | Species | denotes | patients | Tax:9606 |
122 | 1384-1392 | Species | denotes | patients | Tax:9606 |
123 | 2117-2125 | Species | denotes | patients | Tax:9606 |
124 | 2270-2278 | Species | denotes | patients | Tax:9606 |
125 | 2493-2501 | Species | denotes | patients | Tax:9606 |
126 | 1529-1532 | Chemical | denotes | CDs | MESH:D002104 |
127 | 1323-1326 | Disease | denotes | IBD | MESH:D015212 |
128 | 1380-1383 | Disease | denotes | IBD | MESH:D015212 |
129 | 1413-1421 | Disease | denotes | COVID-19 | MESH:C000657245 |
130 | 1472-1475 | Disease | denotes | IBD | MESH:D015212 |
131 | 1914-1923 | Disease | denotes | UC rectum | MESH:D012004 |
132 | 1970-1973 | Disease | denotes | IBD | MESH:D015212 |
133 | 2057-2060 | Disease | denotes | IBD | MESH:D015212 |
134 | 2254-2257 | Disease | denotes | IBD | MESH:D015212 |
135 | 2266-2269 | Disease | denotes | IBD | MESH:D015212 |
136 | 2394-2397 | Disease | denotes | IBD | MESH:D015212 |
137 | 2507-2510 | Disease | denotes | IBD | MESH:D015212 |
148 | 2954-2962 | Species | denotes | patients | Tax:9606 |
149 | 3120-3128 | Species | denotes | patients | Tax:9606 |
150 | 3155-3163 | Species | denotes | patients | Tax:9606 |
151 | 2968-2971 | Disease | denotes | IBD | MESH:D015212 |
152 | 2998-3006 | Disease | denotes | COVID-19 | MESH:C000657245 |
153 | 3104-3112 | Disease | denotes | COVID-19 | MESH:C000657245 |
154 | 3116-3119 | Disease | denotes | IBD | MESH:D015212 |
155 | 3151-3154 | Disease | denotes | IBD | MESH:D015212 |
156 | 3200-3207 | Disease | denotes | anxious | MESH:D001007 |
157 | 3284-3304 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1096-1111 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
T2 | 1102-1111 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/UBERON_0000160 |
T3 | 1179-1183 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T4 | 1616-1622 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T5 | 1776-1781 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T6 | 1831-1836 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
T7 | 1917-1923 | Body_part | denotes | rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T8 | 1991-1996 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T9 | 2337-2342 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T10 | 2355-2361 | Body_part | denotes | rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T11 | 2464-2470 | Body_part | denotes | rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T12 | 2484-2489 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T13 | 2576-2581 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T14 | 2586-2592 | Body_part | denotes | rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T15 | 2781-2786 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
T16 | 2790-2796 | Body_part | denotes | Rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T17 | 2836-2842 | Body_part | denotes | Rectum | http://purl.obolibrary.org/obo/UBERON_0001052 |
T18 | 2892-2897 | Body_part | denotes | ileum | http://purl.obolibrary.org/obo/UBERON_0002116 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 10-17 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
T3 | 21-24 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T5 | 53-61 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T6 | 113-121 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 125-134 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T8 | 144-152 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T9 | 229-239 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T10 | 265-273 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T11 | 308-315 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
T13 | 332-358 | Disease | denotes | Inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
T14 | 360-363 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T16 | 391-409 | Disease | denotes | intestinal disease | http://purl.obolibrary.org/obo/MONDO_0005020 |
T17 | 421-439 | Disease | denotes | ulcerative colitis | http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960 |
T19 | 421-431 | Disease | denotes | ulcerative | http://purl.obolibrary.org/obo/MONDO_0043839 |
T20 | 432-439 | Disease | denotes | colitis | http://purl.obolibrary.org/obo/MONDO_0005292 |
T21 | 441-443 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T22 | 449-464 | Disease | denotes | Crohn's disease | http://purl.obolibrary.org/obo/MONDO_0005011 |
T23 | 466-468 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T24 | 503-510 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
T26 | 520-527 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
T28 | 552-571 | Disease | denotes | intestinal diseases | http://purl.obolibrary.org/obo/MONDO_0005020 |
T29 | 626-634 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T30 | 655-662 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
T32 | 722-725 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T34 | 863-871 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T35 | 875-878 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T37 | 1005-1013 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T38 | 1246-1254 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T39 | 1303-1319 | Disease | denotes | Immune disorders | http://purl.obolibrary.org/obo/MONDO_0005046 |
T40 | 1323-1326 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T42 | 1380-1383 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T44 | 1413-1421 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T45 | 1472-1475 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T47 | 1914-1916 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T48 | 1970-1973 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T50 | 2000-2002 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T51 | 2057-2060 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T53 | 2107-2109 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T54 | 2114-2116 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T55 | 2254-2257 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T57 | 2266-2269 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T59 | 2394-2397 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T61 | 2507-2510 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T63 | 2596-2599 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T65 | 2627-2630 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T67 | 2768-2771 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T69 | 2822-2824 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T70 | 2832-2835 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T72 | 2869-2871 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T73 | 2879-2882 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T75 | 2968-2971 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T77 | 2998-3006 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T78 | 3104-3112 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T79 | 3116-3119 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T81 | 3151-3154 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T83 | 3284-3292 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T84 | 3295-3304 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 288-291 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T2 | 368-369 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T3 | 391-401 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T4 | 391-401 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T5 | 552-562 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T6 | 552-562 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T7 | 635-638 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T8 | 744-745 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T9 | 851-852 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 987-992 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T11 | 1090-1095 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T12 | 1096-1111 | http://purl.obolibrary.org/obo/UBERON_0002108 | denotes | small intestine |
T13 | 1116-1123 | http://purl.obolibrary.org/obo/UBERON_0001155 | denotes | colonic |
T14 | 1124-1134 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T15 | 1135-1140 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T16 | 1179-1183 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T17 | 1179-1183 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T18 | 1507-1508 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T19 | 1776-1781 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T20 | 1831-1836 | http://purl.obolibrary.org/obo/UBERON_0001155 | denotes | colon |
T21 | 1843-1844 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T22 | 1917-1923 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | rectum |
T23 | 1917-1923 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | rectum |
T24 | 1991-1996 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T25 | 2221-2222 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T26 | 2337-2342 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T27 | 2355-2361 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | rectum |
T28 | 2355-2361 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | rectum |
T29 | 2464-2470 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | rectum |
T30 | 2464-2470 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | rectum |
T31 | 2484-2489 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T32 | 2576-2581 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T33 | 2586-2592 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | rectum |
T34 | 2586-2592 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | rectum |
T35 | 2781-2786 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T36 | 2790-2796 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | Rectum |
T37 | 2790-2796 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | Rectum |
T38 | 2836-2842 | http://purl.obolibrary.org/obo/UBERON_0001052 | denotes | Rectum |
T39 | 2836-2842 | http://purl.obolibrary.org/obo/UBERON_0006866 | denotes | Rectum |
T40 | 2892-2897 | http://purl.obolibrary.org/obo/UBERON_0002116 | denotes | ileum |
T41 | 3030-3031 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 466-468 | Chemical | denotes | CD | http://purl.obolibrary.org/obo/CHEBI_8673 |
T2 | 928-939 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T3 | 967-974 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T4 | 1063-1069 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
T5 | 2000-2002 | Chemical | denotes | CD | http://purl.obolibrary.org/obo/CHEBI_8673 |
T6 | 2069-2076 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T7 | 2114-2116 | Chemical | denotes | CD | http://purl.obolibrary.org/obo/CHEBI_8673 |
T8 | 2869-2871 | Chemical | denotes | CD | http://purl.obolibrary.org/obo/CHEBI_8673 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-61 | Sentence | denotes | Excessive anxiety in IBD patients is unnecessary for COVID-19 |
T2 | 63-77 | Sentence | denotes | To the editor, |
T3 | 78-210 | Sentence | denotes | Currently, 2019 novel coronavirus (SARS-CoV-2) infection disease (COVID-19) broke out in Wuhan, China and spread worldwide [1], [2]. |
T4 | 211-331 | Sentence | denotes | Due to the highly infectious and pathogenic nature of SARS-CoV-2, the public has shown excessive anxiety and even panic. |
T5 | 332-515 | Sentence | denotes | Inflammatory bowel disease (IBD) is a chronic non-specific intestinal disease, including ulcerative colitis (UC) and Crohn's disease (CD), and many of these patients have anxiety [3]. |
T6 | 516-669 | Sentence | denotes | The anxiety not only comes from the intestinal diseases that already exist, the current epidemic situation of COVID-19 has also made their anxiety worse. |
T7 | 670-811 | Sentence | denotes | Emotions are an important part of the management of IBD patients, because a less optimistic attitude can make their bowel symptoms recur [4]. |
T8 | 812-888 | Sentence | denotes | To date, there have been no reports of a confirmed COVID-19 in IBD patients. |
T9 | 889-1086 | Sentence | denotes | As known, the coronavirus binds to the angiotensin-converting enzyme 2 (ACE2) protein, enters the cells, leading to COVID-19 with the contribution of transmembrane protease, serine 2 (TMPRSS2) [5]. |
T10 | 1087-1188 | Sentence | denotes | In human small intestine and colonic epithelial cells, ACE2 exhibits higher expression than lung [6]. |
T11 | 1189-1302 | Sentence | denotes | According to autopsy results, the bowel of patients with COVID-19 appeared segmental narrowing and expansion [7]. |
T12 | 1303-1422 | Sentence | denotes | Immune disorders in IBD patients, coupled with current research reports, are IBD patients more susceptible to COVID-19? |
T13 | 1423-1489 | Sentence | denotes | We could obtain some information from the public IBD database [8]. |
T14 | 1490-1591 | Sentence | denotes | After screening, a total of 23 UCs, 37 CDs, and 21 non-IBDs were included in the analysis (Table 1 ). |
T15 | 1592-1669 | Sentence | denotes | Each subject had paired tissue samples of rectal and terminal ileal biopsies. |
T16 | 1670-1883 | Sentence | denotes | Analysis of the transcriptome data of these samples, we found that the expression of ACE2 in the terminal ileum was significantly higher than that in the rectal colon, with a fold change of 9.8 times (P < 0.001). |
T17 | 1884-1974 | Sentence | denotes | The expression of ACE2 in the UC rectum was not significantly higher than that in non-IBD. |
T18 | 1975-2061 | Sentence | denotes | In the terminal ileum of CD, ACE2 expression was also not higher than that of non-IBD. |
T19 | 2062-2155 | Sentence | denotes | At the protein level, ACE2 was not higher in UC and CD patients than in healthy controls [9]. |
T20 | 2156-2279 | Sentence | denotes | These results indicate that the expression of ACE2 does not show a significant difference between IBD and non-IBD patients. |
T21 | 2280-2375 | Sentence | denotes | In addition, TMPRSS2 expression is lower in the terminal ileum than in the rectum (P = 0.005). |
T22 | 2376-2511 | Sentence | denotes | Compared with non-IBD, there was no significant difference in TMPRSS2 expression in the rectum and terminal ileum of patients with IBD. |
T23 | 2512-2631 | Sentence | denotes | Table 1 The expression of ACE2 and TMPRSS2 mRNA in the terminal ileum and rectum of IBD patients compared with non-IBD. |
T24 | 2632-2689 | Sentence | denotes | The data used for analysis were from the IBDMDB database. |
T25 | 2690-2723 | Sentence | denotes | Subjects Biopsy site ACE2 TMPRSS2 |
T26 | 2724-2763 | Sentence | denotes | Fold Change P-value Fold Change P-value |
T27 | 2764-2821 | Sentence | denotes | Non-IBD Terminal ileum vs Rectum 9.8 < 0.001 0.5707 0.005 |
T28 | 2822-2868 | Sentence | denotes | UC vs non-IBD Rectum 1.0639 0.844 1.1138 0.576 |
T29 | 2869-2924 | Sentence | denotes | CD vs non-IBD Terminal ileum 0.71395 0.248 0.9851 0.933 |
T30 | 2925-3007 | Sentence | denotes | Therefore, we speculate that patients with IBD may not be susceptible to COVID-19. |
T31 | 3008-3129 | Sentence | denotes | However, this is only a theoretical guess, and we need to further understand the actual risk of COVID-19 in IBD patients. |
T32 | 3130-3208 | Sentence | denotes | At least, in theory, IBD patients don’t need to be overly worried and anxious. |
T33 | 3209-3305 | Sentence | denotes | Like everyone else, personal protection is an important measure to prevent SARS-CoV-2 infection. |
T34 | 3307-3327 | Sentence | denotes | Author contributions |
T35 | 3328-3480 | Sentence | denotes | Hong-Gang Wang and Xiao-Zhong Yang designed the research; Hong-Gang Wang and Rui Xie analyzed the data; Hong-Gang Wang and Tian-Heng Ma wrote the paper. |
T36 | 3482-3504 | Sentence | denotes | Disclosure of interest |
T37 | 3505-3562 | Sentence | denotes | The authors declare that they have no competing interest. |
T38 | 3564-3580 | Sentence | denotes | Acknowledgements |
T39 | 3581-3586 | Sentence | denotes | None. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 10-17 | Phenotype | denotes | anxiety | http://purl.obolibrary.org/obo/HP_0000739 |
T2 | 21-24 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T3 | 308-315 | Phenotype | denotes | anxiety | http://purl.obolibrary.org/obo/HP_0000739 |
T4 | 332-358 | Phenotype | denotes | Inflammatory bowel disease | http://purl.obolibrary.org/obo/HP_0002037 |
T5 | 360-363 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T6 | 421-439 | Phenotype | denotes | ulcerative colitis | http://purl.obolibrary.org/obo/HP_0100279 |
T7 | 441-443 | Phenotype | denotes | UC | http://purl.obolibrary.org/obo/HP_0100279 |
T8 | 449-464 | Phenotype | denotes | Crohn's disease | http://purl.obolibrary.org/obo/HP_0100280 |
T9 | 466-468 | Phenotype | denotes | CD | http://purl.obolibrary.org/obo/HP_0100280 |
T10 | 503-510 | Phenotype | denotes | anxiety | http://purl.obolibrary.org/obo/HP_0000739 |
T11 | 520-527 | Phenotype | denotes | anxiety | http://purl.obolibrary.org/obo/HP_0000739 |
T12 | 655-662 | Phenotype | denotes | anxiety | http://purl.obolibrary.org/obo/HP_0000739 |
T13 | 722-725 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T14 | 875-878 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T15 | 1323-1326 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T16 | 1380-1383 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T17 | 1472-1475 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T18 | 1914-1916 | Phenotype | denotes | UC | http://purl.obolibrary.org/obo/HP_0100279 |
T19 | 1970-1973 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T20 | 2000-2002 | Phenotype | denotes | CD | http://purl.obolibrary.org/obo/HP_0100280 |
T21 | 2057-2060 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T22 | 2107-2109 | Phenotype | denotes | UC | http://purl.obolibrary.org/obo/HP_0100279 |
T23 | 2114-2116 | Phenotype | denotes | CD | http://purl.obolibrary.org/obo/HP_0100280 |
T24 | 2254-2257 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T25 | 2266-2269 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T26 | 2394-2397 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T27 | 2507-2510 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T28 | 2596-2599 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T29 | 2627-2630 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T30 | 2768-2771 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T31 | 2822-2824 | Phenotype | denotes | UC | http://purl.obolibrary.org/obo/HP_0100279 |
T32 | 2832-2835 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T33 | 2869-2871 | Phenotype | denotes | CD | http://purl.obolibrary.org/obo/HP_0100280 |
T34 | 2879-2882 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T35 | 2968-2971 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T36 | 3116-3119 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T37 | 3151-3154 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |