PMC:7214327 / 1769-2134 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2","span":{"begin":16,"end":26},"obj":"Body_part"},{"id":"T3","span":{"begin":132,"end":135},"obj":"Body_part"},{"id":"T4","span":{"begin":146,"end":149},"obj":"Body_part"},{"id":"T5","span":{"begin":224,"end":227},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma82740"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T10","span":{"begin":330,"end":338},"obj":"Disease"},{"id":"T11","span":{"begin":343,"end":351},"obj":"Disease"}],"attributes":[{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T13","span":{"begin":14,"end":15},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":105,"end":106},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T15","span":{"begin":185,"end":188},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T16","span":{"begin":241,"end":242},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T15","span":{"begin":16,"end":26},"obj":"Chemical"},{"id":"T16","span":{"begin":49,"end":61},"obj":"Chemical"},{"id":"T17","span":{"begin":85,"end":87},"obj":"Chemical"}],"attributes":[{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_18036"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_73662"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T4","span":{"begin":224,"end":237},"obj":"http://purl.obolibrary.org/obo/GO_0032774"},{"id":"T5","span":{"begin":228,"end":237},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T17","span":{"begin":0,"end":365},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"69","span":{"begin":162,"end":166},"obj":"Gene"},{"id":"70","span":{"begin":355,"end":359},"obj":"Gene"},{"id":"78","span":{"begin":305,"end":318},"obj":"Species"},{"id":"79","span":{"begin":320,"end":328},"obj":"Species"},{"id":"80","span":{"begin":330,"end":338},"obj":"Species"},{"id":"81","span":{"begin":343,"end":353},"obj":"Species"},{"id":"91","span":{"begin":0,"end":10},"obj":"Chemical"},{"id":"92","span":{"begin":70,"end":73},"obj":"Chemical"},{"id":"93","span":{"begin":81,"end":84},"obj":"Chemical"}],"attributes":[{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"Gene:43740578"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Gene:43740578"},{"id":"A78","pred":"tao:has_database_id","subj":"78","obj":"Tax:11118"},{"id":"A79","pred":"tao:has_database_id","subj":"79","obj":"Tax:1335626"},{"id":"A80","pred":"tao:has_database_id","subj":"80","obj":"Tax:694009"},{"id":"A81","pred":"tao:has_database_id","subj":"81","obj":"Tax:2697049"},{"id":"A91","pred":"tao:has_database_id","subj":"91","obj":"MESH:C000606551"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"MESH:C000606551"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"MESH:C000606551"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Remdesivir is a nucleotide analogue (4), and the triphosphate form of RDV, i.e., RDV-TP is being used as a substrate for many viral RNA-dependent RNA polymerase (RdRp) complexes and it has been reported to inhibit the viral RNA synthesis by a specific mechanism of delayed chain termination for all three coronaviruses (MERS-CoV, SARS-CoV and SARS-CoV-2) RdRp (10)."}