PMC:7212965 / 42851-43234 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T95","span":{"begin":26,"end":29},"obj":"Body_part"},{"id":"T96","span":{"begin":93,"end":98},"obj":"Body_part"},{"id":"T97","span":{"begin":160,"end":165},"obj":"Body_part"},{"id":"T98","span":{"begin":210,"end":215},"obj":"Body_part"},{"id":"T99","span":{"begin":344,"end":347},"obj":"Body_part"}],"attributes":[{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T73","span":{"begin":93,"end":98},"obj":"Body_part"},{"id":"T74","span":{"begin":160,"end":165},"obj":"Body_part"},{"id":"T75","span":{"begin":210,"end":215},"obj":"Body_part"}],"attributes":[{"id":"A73","pred":"uberon_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A74","pred":"uberon_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A75","pred":"uberon_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T220","span":{"begin":99,"end":105},"obj":"Disease"},{"id":"T221","span":{"begin":154,"end":173},"obj":"Disease"},{"id":"T222","span":{"begin":352,"end":363},"obj":"Disease"},{"id":"T223","span":{"begin":352,"end":361},"obj":"Disease"},{"id":"T224","span":{"begin":373,"end":382},"obj":"Disease"}],"attributes":[{"id":"A220","pred":"mondo_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A221","pred":"mondo_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/MONDO_0019542"},{"id":"A222","pred":"mondo_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/MONDO_0005231"},{"id":"A223","pred":"mondo_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/MONDO_0002251"},{"id":"A224","pred":"mondo_id","subj":"T224","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T320","span":{"begin":40,"end":41},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T321","span":{"begin":93,"end":98},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T322","span":{"begin":93,"end":98},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T323","span":{"begin":160,"end":165},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T324","span":{"begin":160,"end":165},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T325","span":{"begin":364,"end":369},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T198","span":{"begin":154,"end":173},"obj":"Phenotype"},{"id":"T199","span":{"begin":352,"end":361},"obj":"Phenotype"}],"attributes":[{"id":"A198","pred":"hp_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/HP_0006554"},{"id":"A199","pred":"hp_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/HP_0012115"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-sentences","denotations":[{"id":"T288","span":{"begin":0,"end":383},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1180","span":{"begin":12,"end":20},"obj":"Species"},{"id":"1181","span":{"begin":319,"end":327},"obj":"Species"},{"id":"1184","span":{"begin":26,"end":29},"obj":"Disease"},{"id":"1185","span":{"begin":72,"end":86},"obj":"Disease"},{"id":"1186","span":{"begin":93,"end":105},"obj":"Disease"},{"id":"1187","span":{"begin":154,"end":173},"obj":"Disease"},{"id":"1188","span":{"begin":344,"end":382},"obj":"Disease"}],"attributes":[{"id":"A1180","pred":"tao:has_database_id","subj":"1180","obj":"Tax:9606"},{"id":"A1181","pred":"tao:has_database_id","subj":"1181","obj":"Tax:9606"},{"id":"A1184","pred":"tao:has_database_id","subj":"1184","obj":"MESH:D015658"},{"id":"A1185","pred":"tao:has_database_id","subj":"1185","obj":"MESH:D056486"},{"id":"A1186","pred":"tao:has_database_id","subj":"1186","obj":"MESH:D017093"},{"id":"A1187","pred":"tao:has_database_id","subj":"1187","obj":"MESH:D017114"},{"id":"A1188","pred":"tao:has_database_id","subj":"1188","obj":"MESH:D006526"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, in patients with HIV, there is a well-documented known risk of hepatotoxicity, with liver injury severity ranging from mild enzyme elevations to acute liver failure.91 Moderate-to-severe elevations in serum aminotransferases, defined as more than 5 times the ULN, are found in 3%–10%.91 Rates may be higher in patients with concurrent HIV and hepatitis C virus co-infection."}