PMC:7212965 / 35713-36612
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T75 | 147-155 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T76 | 292-297 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T77 | 475-480 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T58 | 292-297 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T59 | 475-480 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T164 | 172-181 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T165 | 265-271 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T166 | 332-340 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T167 | 379-391 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T168 | 462-487 | Disease | denotes | drug-induced liver injury | http://purl.obolibrary.org/obo/MONDO_0005359 |
| T169 | 481-487 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T170 | 620-628 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T171 | 849-857 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T281 | 235-240 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T282 | 292-297 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T283 | 292-297 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T284 | 475-480 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T285 | 475-480 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T286 | 595-596 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T54 | 201-205 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T55 | 462-466 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T56 | 832-836 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T159 | 147-161 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
| T160 | 172-181 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T161 | 182-187 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
| T162 | 189-195 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
| T163 | 372-391 | Phenotype | denotes | portal inflammation | http://purl.obolibrary.org/obo/HP_0033196 |
| T164 | 396-420 | Phenotype | denotes | microvesicular steatosis | http://purl.obolibrary.org/obo/HP_0001414 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T7 | 115-136 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
| T8 | 379-391 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32407808-32145190-43469306 | 272-273 | 32145190 | denotes | 7 |
| 32407808-32085846-43469307 | 488-490 | 32085846 | denotes | 81 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T227 | 0-899 | Sentence | denotes | The available studies suggest that abnormal LFTs are more commonly attributable to secondary effects (eg, systemic inflammatory response syndrome, cytokine storm, ischemic hepatitis/shock, sepsis, and drug hepatotoxicity) than primary virus-mediated hepatocellular injury.7 , 9 , 80 However, liver histopathology from patients with COVID-19 have revealed mild lobular and portal inflammation and microvesicular steatosis suggestive of either virally mediated or drug-induced liver injury.81 In addition, some studies have revealed that abnormal LFTs at hospital admission may be associated with a higher risk for severe COVID-19 (odds ratio, 2.73; 95% CI, 1.19–6.3).9 Therefore, we advise checking baseline LFTs in all patients on admission and monitoring of LFTs throughout the hospitalization, particularly in patients undergoing drug therapy for COVID-19 associated with potential hepatotoxicity. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 895 | 318-326 | Species | denotes | patients | Tax:9606 |
| 896 | 719-727 | Species | denotes | patients | Tax:9606 |
| 897 | 812-820 | Species | denotes | patients | Tax:9606 |
| 907 | 163-187 | Disease | denotes | ischemic hepatitis/shock | MESH:D012772 |
| 908 | 189-195 | Disease | denotes | sepsis | MESH:D018805 |
| 909 | 201-220 | Disease | denotes | drug hepatotoxicity | MESH:D056486 |
| 910 | 250-271 | Disease | denotes | hepatocellular injury | MESH:D056486 |
| 911 | 332-340 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 912 | 379-391 | Disease | denotes | inflammation | MESH:D007249 |
| 913 | 396-420 | Disease | denotes | microvesicular steatosis | MESH:D005234 |
| 914 | 475-487 | Disease | denotes | liver injury | MESH:D017093 |
| 915 | 536-549 | Disease | denotes | abnormal LFTs | MESH:D018376 |
| 916 | 620-628 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 917 | 849-857 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 918 | 884-898 | Disease | denotes | hepatotoxicity | MESH:D056486 |