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PMC:7212949 / 28131-34187 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T146 834-840 Body_part denotes saliva http://purl.org/sig/ont/fma/fma59862
T147 849-854 Body_part denotes feces http://purl.org/sig/ont/fma/fma64183
T148 888-903 Body_part denotes lymphoid tissue http://purl.org/sig/ont/fma/fma55220
T149 954-969 Body_part denotes lymphoid tissue http://purl.org/sig/ont/fma/fma55220
T150 1956-1961 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T151 2053-2060 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 2209-2214 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T153 2215-2222 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T154 2262-2267 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T155 2269-2277 Body_part denotes pancreas http://purl.org/sig/ont/fma/fma7198
T156 2302-2308 Body_part denotes spleen http://purl.org/sig/ont/fma/fma7196
T157 2342-2347 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T158 2378-2389 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T159 2417-2428 Body_part denotes lymphocytic http://purl.org/sig/ont/fma/fma62863
T160 2491-2496 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T161 2551-2557 Body_part denotes Spleen http://purl.org/sig/ont/fma/fma7196
T162 2567-2577 Body_part denotes white pulp http://purl.org/sig/ont/fma/fma62805
T163 2595-2599 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T164 2663-2668 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 2677-2688 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T166 2727-2743 Body_part denotes pancreatic islet http://purl.org/sig/ont/fma/fma16016
T167 2744-2749 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T168 2885-2893 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T169 2915-2920 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T170 2961-2966 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T171 2967-2972 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T172 3011-3018 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T173 3086-3091 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T174 3165-3170 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T175 3240-3246 Body_part denotes Spleen http://purl.org/sig/ont/fma/fma7196
T176 3383-3389 Body_part denotes spleen http://purl.org/sig/ont/fma/fma7196
T177 3551-3558 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T178 4039-4044 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T179 4101-4114 Body_part denotes T lymphocytes http://purl.org/sig/ont/fma/fma62870
T180 4142-4157 Body_part denotes hepatic lobules http://purl.org/sig/ont/fma/fma14471
T181 4169-4179 Body_part denotes parenchyma http://purl.org/sig/ont/fma/fma45732
T182 4260-4271 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T183 4295-4309 Body_part denotes hepatic plates http://purl.org/sig/ont/fma/fma14655
T184 4365-4375 Body_part denotes sinusoidal http://purl.org/sig/ont/fma/fma63131
T185 4421-4432 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T186 4637-4642 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T187 4975-4980 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T188 5015-5020 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T189 5085-5090 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T190 5237-5248 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T191 5416-5421 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T192 5565-5575 Body_part denotes hepatocyte http://purl.org/sig/ont/fma/fma14515
T193 5625-5633 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T194 5774-5781 Body_part denotes alanine http://purl.org/sig/ont/fma/fma82749

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T87 834-840 Body_part denotes saliva http://purl.obolibrary.org/obo/UBERON_0001836
T88 849-854 Body_part denotes feces http://purl.obolibrary.org/obo/UBERON_0001988
T89 888-903 Body_part denotes lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001744
T90 897-903 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T91 954-969 Body_part denotes lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001744
T92 963-969 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T93 1956-1961 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T94 2209-2214 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T95 2262-2267 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T96 2269-2277 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264
T97 2302-2308 Body_part denotes spleen http://purl.obolibrary.org/obo/UBERON_0002106
T98 2491-2496 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T99 2551-2557 Body_part denotes Spleen http://purl.obolibrary.org/obo/UBERON_0002106
T100 2915-2920 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T101 2967-2972 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T102 3086-3091 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T103 3165-3170 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T104 3240-3246 Body_part denotes Spleen http://purl.obolibrary.org/obo/UBERON_0002106
T105 3383-3389 Body_part denotes spleen http://purl.obolibrary.org/obo/UBERON_0002106
T106 4039-4044 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T107 4169-4179 Body_part denotes parenchyma http://purl.obolibrary.org/obo/UBERON_0000353
T108 4637-4642 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T109 4975-4980 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T110 5015-5020 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T111 5416-5421 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T221 37-45 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T222 236-244 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T223 465-473 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T224 666-674 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T225 698-702 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T226 793-801 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T227 1012-1020 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T228 1035-1043 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T229 1045-1049 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T230 1674-1682 Disease denotes Diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T231 2269-2277 Disease denotes pancreas http://purl.obolibrary.org/obo/MONDO_0021040
T232 2538-2550 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T233 2943-2952 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T234 3144-3162 Disease denotes immune dysfunction http://purl.obolibrary.org/obo/MONDO_0005046
T235 3390-3396 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T236 3433-3446 Disease denotes hyperglycemia http://purl.obolibrary.org/obo/MONDO_0002909
T237 3526-3534 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T238 3551-3586 Disease denotes insulin dependent diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005147
T239 3569-3577 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T240 3609-3617 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T241 4059-4071 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T242 4518-4527 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T243 4554-4572 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T244 4592-4608 Disease denotes hepatitis, viral http://purl.obolibrary.org/obo/MONDO_0006011
T245 4592-4601 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T246 4649-4657 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T247 4975-4988 Disease denotes liver disease http://purl.obolibrary.org/obo/MONDO_0005154
T248 5015-5028 Disease denotes liver disease http://purl.obolibrary.org/obo/MONDO_0005154
T249 5974-5978 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T250 5984-6017 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T279 261-263 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T280 478-479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T281 608-609 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T282 873-883 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T283 888-903 http://purl.obolibrary.org/obo/UBERON_0001744 denotes lymphoid tissue
T284 954-969 http://purl.obolibrary.org/obo/UBERON_0001744 denotes lymphoid tissue
T285 1956-1961 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T286 1956-1961 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T287 2209-2214 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T288 2209-2214 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T289 2240-2241 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T290 2244-2249 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T291 2262-2267 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T292 2262-2267 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T293 2269-2277 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
T294 2280-2285 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T295 2302-2308 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleen
T296 2342-2347 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T297 2473-2478 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T298 2491-2496 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T299 2491-2496 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T300 2524-2525 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T301 2551-2557 http://purl.obolibrary.org/obo/UBERON_0002106 denotes Spleen
T302 2595-2599 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T303 2642-2645 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T304 2642-2645 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T305 2648-2651 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T306 2658-2661 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T307 2663-2668 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T308 2671-2675 http://purl.obolibrary.org/obo/PR_000002064 denotes CD68
T309 2727-2743 http://purl.obolibrary.org/obo/UBERON_0000006 denotes pancreatic islet
T310 2744-2749 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T311 2915-2920 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T312 2915-2920 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T313 2961-2966 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T314 2967-2972 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T315 2967-2972 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T316 2990-2995 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T317 3086-3091 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T318 3086-3091 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T319 3165-3170 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T320 3165-3170 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T321 3188-3193 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T322 3240-3246 http://purl.obolibrary.org/obo/UBERON_0002106 denotes Spleen
T323 3383-3389 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleen
T324 3551-3558 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T325 3926-3927 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T326 4014-4015 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T327 4033-4034 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T328 4037-4038 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T329 4039-4044 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T330 4039-4044 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T331 4087-4090 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T332 4096-4099 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T333 4478-4480 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T334 4540-4542 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T335 4637-4642 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T336 4637-4642 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T337 4975-4980 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T338 4975-4980 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T339 5015-5020 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T340 5015-5020 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T341 5069-5072 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T342 5078-5081 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T343 5083-5090 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T344 5130-5131 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T345 5189-5190 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T346 5258-5259 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T347 5262-5263 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T348 5380-5385 http://purl.obolibrary.org/obo/UBERON_0003101 denotes males
T349 5380-5385 http://www.ebi.ac.uk/efo/EFO_0000970 denotes males
T350 5416-5421 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T351 5416-5421 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T352 5554-5559 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T353 5618-5619 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T82 18-20 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T83 137-139 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T84 176-178 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T85 570-572 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T86 765-767 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T87 1771-1774 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T88 1809-1812 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T89 1831-1834 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T90 1999-2002 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T91 2053-2060 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T92 2215-2222 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T94 2519-2521 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T95 2783-2786 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T96 3011-3018 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T97 3104-3110 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T98 3217-3222 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T99 3295-3302 Chemical denotes Steroid http://purl.obolibrary.org/obo/CHEBI_35341
T100 3450-3453 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T101 3551-3558 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T102 3707-3709 Chemical denotes Al http://purl.obolibrary.org/obo/CHEBI_28984
T103 3975-3978 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T104 3993-3996 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T105 4646-4648 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T106 5134-5137 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T107 5682-5685 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T108 5774-5781 Chemical denotes alanine http://purl.obolibrary.org/obo/CHEBI_16449
T109 5800-5803 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T110 5805-5814 Chemical denotes aspartate http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314
T113 5838-5845 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T114 6046-6055 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T30 2312-2321 http://purl.obolibrary.org/obo/GO_0097194 denotes Apoptosis
T31 2312-2321 http://purl.obolibrary.org/obo/GO_0006915 denotes Apoptosis
T32 2351-2358 http://purl.obolibrary.org/obo/GO_0140014 denotes mitosis
T33 2351-2358 http://purl.obolibrary.org/obo/GO_0000278 denotes mitosis
T34 2538-2550 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T35 4059-4071 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T36 5933-5946 http://purl.obolibrary.org/obo/GO_0003968 denotes transcriptase
T37 5933-5946 http://purl.obolibrary.org/obo/GO_0003899 denotes transcriptase

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T181 236-244 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T182 304-320 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T183 336-350 Phenotype denotes abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T184 465-473 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T185 666-674 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T186 2885-2899 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T187 3135-3140 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T188 3433-3446 Phenotype denotes hyperglycemia http://purl.obolibrary.org/obo/HP_0003074
T189 3551-3586 Phenotype denotes insulin dependent diabetes mellitus http://purl.obolibrary.org/obo/HP_0100651
T190 4052-4071 Phenotype denotes portal inflammation http://purl.obolibrary.org/obo/HP_0033196
T191 4511-4527 Phenotype denotes severe infection http://purl.obolibrary.org/obo/HP_0032169
T192 4592-4601 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T193 4975-4988 Phenotype denotes liver disease http://purl.obolibrary.org/obo/HP_0001392
T194 5015-5028 Phenotype denotes liver disease http://purl.obolibrary.org/obo/HP_0001392
T195 5365-5370 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T196 5407-5430 Phenotype denotes Abnormal liver function http://purl.obolibrary.org/obo/HP_0002910
T197 5625-5639 Phenotype denotes Cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T299 0-275 Sentence denotes Gastrointestinal (GI) involvement in SARS-CoV was common and occurred at different stages of the disease; rarely, patients reported only GI symptoms.68, 69, 70 The most common GI presentation was loss of appetite (up to 55%) and watery diarrhea (up to 76%)69 , 71 (Table 3 ).
T300 276-427 Sentence denotes Patients also complained of nausea, vomiting (14-22.2%) and abdominal pain (3.5-12.6%).72 The association between symptoms and outcomes had been mixed.
T301 428-972 Sentence denotes Leung et al found that patients with diarrhea had a higher likelihood of requiring ICU admission and ventilatory support.68 Others found that GI symptoms at presentation conferred a better prognosis.69 Others found no association between diarrhea and the development of ARDS or the requirement of ventilatory support.70 The mechanism of GI symptoms is unclear, but SARS-CoV particles have been detected in saliva (100%), feces (97%) and mucosal epithelial and lymphoid tissue of affected patients with associated depletion of lymphoid tissue.72
T302 973-1044 Sentence denotes Table 3 Hepatobiliary manifestation of SARS-CoV, MERS-CoV and COVID-19.
T303 1045-1101 Sentence denotes SARS (only studies with large study population included)
T304 1102-1555 Sentence denotes Study Duan et al (2003)N = 154, confirmed casesRetrospective study Ding et al (2004)N = 8 (4 confirmed cases, 4 control)Clinicopathologic study Chau et al (2004)N = 3, confirmedCase report Zhao et al (2004)N = 169, confirmed casesRetrospective study Yang et al (2005)N = 168, confirmed casesRetrospective study Zhan et al (2006)N = 12 (6 confirmed cases, 6 controls)Clinicopathologic study Yang et al (2010)N = 539 (520 confirmed cases)Prospective study
T305 1556-1704 Sentence denotes Clinical Features Hepatic dysfunction Hepatic dysfunction Hepatic dysfunction Hepatic dysfunction Hepatic dysfunction Diabetes:• 35.9% within 3 days
T306 1705-1727 Sentence denotes • 51.3% within 2 weeks
T307 1728-1782 Sentence denotes Key findings on investigations • ↑ALT &/or AST (37.7%)
T308 1783-1797 Sentence denotes • ↑ALT (70.7%)
T309 1798-1820 Sentence denotes • ↑ALT and AST (22.4%)
T310 1821-1869 Sentence denotes • ALT and AST normalized within 2 weeks in 75.9%
T311 1870-1887 Sentence denotes • ↑T. bili (8.4%)
T312 1888-1904 Sentence denotes • ↑Albumin (24%)
T313 1905-1935 Sentence denotes • ↓ Prealbumin (28.6%) • ↑ ALT
T314 1936-1994 Sentence denotes • + viral RT-PCR in liver, not sera • ↑ ALT (32.76-62.50%)
T315 1995-2017 Sentence denotes • ↑ AST (13.04-40.00%)
T316 2018-2044 Sentence denotes • ↓ Albumin (40.35-72.00%)
T317 2045-2090 Sentence denotes • Total protein remained normal ↑ ALT:• Peak:
T318 2091-2110 Sentence denotes 111.32 ± 160.24 U/L
T319 2111-2126 Sentence denotes • At admission:
T320 2127-2133 Sentence denotes 52.5%,
T321 2134-2147 Sentence denotes • First week:
T322 2148-2153 Sentence denotes 71.8%
T323 2154-2168 Sentence denotes • Second week:
T324 2169-2174 Sentence denotes 85.7%
T325 2175-2188 Sentence denotes • Third week:
T326 2189-2194 Sentence denotes 85.2%
T327 2195-2222 Sentence denotes • ↓ Albumin ↑ blood glucose
T328 2223-2277 Sentence denotes Histopathology N/A • Virus detected in liver, pancreas
T329 2278-2327 Sentence denotes • Virus not detected in spleen. • Apoptosis (3/3)
T330 2328-2364 Sentence denotes • Accumulated cells in mitosis (2/3)
T331 2365-2389 Sentence denotes • Ballooning hepatocytes
T332 2390-2441 Sentence denotes • Mild to moderate lobular lymphocytic infiltration
T333 2442-2470 Sentence denotes • Ki-67 + nuclei (0.5-11.4%)
T334 2471-2584 Sentence denotes • Virus detected in liver by RT-PCR, but not by EM N/A Nonspecific inflammation Spleen:• Severe white pulp damage
T335 2585-2612 Sentence denotes • Altered cell distribution
T336 2613-2668 Sentence denotes • Markedly reduced or absent CD3+, CD4+, and CD8+ cells
T337 2669-2749 Sentence denotes • CD68+ macrophages most numerous ACE2 receptors found in pancreatic islet cells
T338 2750-2850 Sentence denotes Key study findings and message • AST/ALT elevation rates associated with disease severity (P < 0.05)
T339 2851-3162 Sentence denotes • Possibly beneficial to suppress cytokine storm in early stage Liver may also be target of infection besides lungs Liver damage likely by virus directly Total protein remained normal despite albuminemia • No association found between liver damage, and oxygen saturation or degree of fever or immune dysfunction
T340 3163-3202 Sentence denotes • Liver damage likely by virus directly
T341 3203-3292 Sentence denotes • Hepatotoxic drugs may contribute • Spleen damage most likely due to direct viral attack
T342 3293-3328 Sentence denotes • Steroid medication may contribute
T343 3329-3466 Sentence denotes • Indirect viral mechanism, perhaps vascular, causing spleen injury • Higher mortality in patients with hyperglycemia, ↑ AST (P < 0.0001)
T344 3467-3523 Sentence denotes • Mortality not higher in patients with ↑ ALT (P = 0.35)
T345 3524-3586 Sentence denotes • SARS-CoV may cause acute insulin dependent diabetes mellitus
T346 3587-3641 Sentence denotes • 5% (2/39) still had diabetes 3 years after discharge
T347 3642-3646 Sentence denotes MERS
T348 3647-3827 Sentence denotes Study Saad et al (2014)N = 70, confirmed casesRetrospective Al-Hameed et al (2016)N = 8, confirmed casesProspective study Alsaad et al (2017)N = 1, confirmed casesClinicopathologic
T349 3828-3927 Sentence denotes Clinical Features Hepatic dysfunction (31.4%) Hepatic dysfunction later during ICU stay (62.5%) N/A
T350 3928-3970 Sentence denotes Key findings on investigations • ↓ Albumin
T351 3971-3978 Sentence denotes • ↑ AST
T352 3979-4001 Sentence denotes • ↑ T.bil • ↑ AST, ALT
T353 4002-4015 Sentence denotes • ↑ T.bil N/A
T354 4016-4115 Sentence denotes Histopathology N/A N/A Liver:• Mild portal inflammation, chronic, with CD4+ and CD8+ T lymphocytes.
T355 4116-4157 Sentence denotes Necroinflammatory foci in hepatic lobules
T356 4158-4237 Sentence denotes • Reactive parenchyma with mild hydropic degeneration, more in perivenular area
T357 4238-4271 Sentence denotes • Rare multinucleated hepatocytes
T358 4272-4309 Sentence denotes • Mild disarray of the hepatic plates
T359 4310-4437 Sentence denotes • Minimal macrovesicular perivenular steatotic change, sinusoidal congestion, hemorrhage and focal perivenular hepatocytes loss
T360 4438-4648 Sentence denotes Key study findings and message Albumin <35 g/L at diagnosis predictor of severe infection (P = 0.026) 41% developed multiorgan failure Portal and lobular hepatitis, viral particles not identified in liver on EM
T361 4649-4657 Sentence denotes COVID-19
T362 4658-4895 Sentence denotes Study Fan et al (2020)N = 148, confirmed casesRetrospective study Chai et al (2020)N = 4 (healthy)Clinicopathologic Huang et al (2020)N = 41, confirmed casesRetrospective study Wang et al (2020)N = 138, confirmed casesRetrospective study
T363 4896-5035 Sentence denotes Clinical features Hepatic dysfunction at admission (50.7%) Preexisting chronic liver disease (2%) Pre-existing chronic liver disease (2.9%)
T364 5036-5171 Sentence denotes Key findings on investigations ↓ CD4+ and CD8+ T cells in patients with hepatic dysfunction N/A ↑ AST (37%)(62% ICU, 25% non-ICU) ↑ LDH
T365 5172-5263 Sentence denotes Histopathology N/A ACE2 expression in cholangiocytes (59.7%) and hepatocytes (2.6%) N/A N/A
T366 5264-5404 Sentence denotes Key study findings and message • Patients with hepatic dysfunction more likely to have moderate-high fever, more in males (P = 0.035, 0.005)
T367 5405-5575 Sentence denotes • Abnormal liver function after admission associated with prolonged stay (P = 0.02) • Hepatic dysfunction more likely due to cholangiocyte damage by virus, not hepatocyte
T368 5576-5768 Sentence denotes • Drug induced damage, SIRS may also play a role Cytokine storm possible associated with disease severity AST, ALT, T.bil, LDH higher in ICU patients (P < 0.001, P = 0.007,P = 0.02, P < 0.001)
T369 5769-6033 Sentence denotes ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; MERS-CoV, middle east respiratory syndrome coronavirus; RT-PCR, reverse transcriptase polymerase chain reaction; SARS-COV, severe acute respiratory syndrome coronavirus; T.
T370 6034-6056 Sentence denotes Bili, total bilirubin.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T885 71-76 UBERON:0000981 denotes t dif
T886 77-82 NCBITaxon:10239 denotes erent
T887 188-193 UBERON:0001443 denotes ion w
T888 205-213 CHEBI:10545;CHEBI:10545 denotes ppetite
T889 242-264 UBERON:0001555 denotes ea (up to 76%)69 , 71
T890 342-350 SP_9 denotes nal pain
T891 352-363 SP_9 denotes 3.5-12.6%).
T892 364-374 SP_9;UBERON:0001004 denotes 2 The asso
T893 375-395 SP_9 denotes iation between sympt
T894 397-405 SP_10 denotes s and ou
T895 407-419 SP_10 denotes omes had bee
T896 420-430 SP_10;UBERON:0001004 denotes mixed. Le
T897 431-451 SP_10 denotes ng et al found that
T898 482-498 UBERON:0005409 denotes gher likelihood
T899 517-525 SP_10 denotes mission
T900 527-535 SP_9 denotes d ventil
T901 540-548 SP_7 denotes support
T902 662-671 UBERON:0000916 denotes een diarr
T903 833-835 UBERON:0005409 denotes s
T904 1047-1049 UBERON:0005409 denotes RS
T905 1247-1252 NCBITaxon:10239 denotes hau e
T906 1275-1284 UBERON:0000483;CL:0000066 denotes rmedCase
T907 1285-1290 CL:0000066 denotes eport
T908 1294-1299 UBERON:0000160 denotes o et
T909 1307-1309 GO:0005783 denotes )N
T910 1326-1336 GO:0005902 denotes casesRetr
T911 1345-1350 NCBITaxon:10239;GO:0006260 denotes stud
T912 1351-1362 GO:0006260 denotes Yang et al
T913 1366-1376 UBERON:0000160 denotes 05)N = 168
T914 1395-1400 NCBITaxon:10239 denotes trosp
T915 1417-1432 UBERON:0002108 denotes et al (2006)N 
T916 1533-1546 UBERON:0001199 denotes ases)Prospect
T917 1603-1618 UBERON:0001744 denotes ysfunction Hepa
T918 1638-1646 SP_10 denotes tic dysf
T919 1669-1678 UBERON:0000483;CL:0000066 denotes tion Diab
T920 1679-1684 CL:0000066 denotes tes:•
T921 1727-1729 UBERON:0005409 denotes K
T922 1870-1875 CHEBI:27026;CHEBI:27026 denotes • ↑T.
T923 1892-1897 NCBITaxon:10239;GO:0006260 denotes lbumi
T924 1898-1909 GO:0006260 denotes (24%) • ↓
T925 2005-2019 UBERON:0001728 denotes 3.04-40.00%) •
T926 2094-2099 NCBITaxon:10239 denotes .32 ±
T927 2103-2113 CHEBI:33282;CHEBI:33282 denotes .24 U/L •
T928 2132-2137 UBERON:0002405 denotes , • F
T929 2160-2171 CL:0000542 denotes nd week: 85
T930 2295-2297 UBERON:0005409 denotes te
T931 2485-2494 UBERON:0000916 denotes ed in liv
T932 2659-2664 UBERON:0001988 denotes D8+ c
T933 2673-2678 NCBITaxon:10239 denotes 68+ m
T934 2700-2705 UBERON:0001988 denotes us AC
T935 2737-2759 UBERON:0001558 denotes islet cells Key study
T936 2788-2793 UBERON:0001988 denotes LT el
T937 2828-2842 UBERON:0000922 denotes se severity (P
T938 2854-2864 UBERON:0000160;CL:0002563 denotes ossibly be
T939 2865-2874 CL:0002563;UBERON:0000483 denotes eficial t
T940 2875-2880 CL:0002563 denotes supp
T941 2895-2900 NCBITaxon:10239;GO:0006260 denotes torm
T942 2901-2912 GO:0006260 denotes n early sta
T943 2953-2963 UBERON:0001004 denotes besides lu
T944 3083-3092 UBERON:0000916 denotes en liver
T945 3181-3183 UBERON:0005409 denotes el
T946 3329-3338 UBERON:0000916 denotes • Indirec
T947 3360-3369 SP_7 denotes haps vasc
T948 3388-3394 UBERON:0001836 denotes n inju
T949 3430-3436 UBERON:0001836 denotes th hyp
T950 3460-3465 UBERON:0001988 denotes .0001
T951 3525-3530 UBERON:0001988 denotes SARS
T952 3732-3734 UBERON:0005409 denotes  8
T953 3763-3774 CHEBI:33282;CHEBI:33282 denotes study Alsaa
T954 3921-3926 UBERON:0001988 denotes %) N/
T955 3956-3961 NCBITaxon:10239 denotes ns •
T956 4034-4039 UBERON:0000981 denotes N/A
T957 4040-4045 NCBITaxon:10239 denotes iver:
T958 4154-4159 UBERON:0001443 denotes les •
T959 4171-4179 CHEBI:10545;CHEBI:10545 denotes renchyma
T960 4204-4207 UBERON:0005409 denotes era
T961 4209-4232 UBERON:0001555 denotes on, more in perivenular
T962 4312-4320 SP_9 denotes Minimal
T963 4322-4333 SP_9 denotes crovesicula
T964 4334-4345 SP_9;UBERON:0001004 denotes perivenula
T965 4346-4366 SP_9 denotes steatotic change, s
T966 4369-4377 SP_10 denotes soidal c
T967 4379-4391 SP_10 denotes gestion, hem
T968 4392-4402 SP_10;UBERON:0001004 denotes rrhage and
T969 4403-4424 SP_10 denotes focal perivenular hep
T970 4468-4475 UBERON:0000025 denotes Albumi
T971 4547-4552 UBERON:0001088 denotes elope
T972 4733-4737 GO:0016265 denotes l (2
T973 4741-4749 SP_10 denotes N = 4 (h
T974 4754-4764 UBERON:0000473 denotes y)Clinicop
T975 4812-4817 UBERON:0002405;GO:0006955 denotes sesRe
T976 4818-4826 GO:0006955 denotes rospecti
T977 4830-4838 SP_9 denotes tudy Wan
T978 4839-4847 SP_9 denotes et al (
T979 4881-4892 PR:000012546 denotes spective st
T980 4896-4901 PR:000001341;PG_7 denotes Clini
T981 4944-4953 GO:0010467 denotes on (50.7%
T982 4957-4965 UBERON:0002113 denotes eexistin
T983 4970-4975 UBERON:0002113 denotes onic
T984 5039-5047 SP_10 denotes finding
T985 5228-5234 UBERON:0002113 denotes .7%) a
T986 5278-5284 UBERON:0002113 denotes ings a
T987 5341-5351 CHEBI:16737;CHEBI:16737 denotes y to have
T988 5379-5384 UBERON:0002113 denotes male
T989 5448-5454 UBERON:0002113 denotes ssocia
T990 5519-5524 NCBITaxon:10239 denotes ely d
T991 5546-5551 UBERON:0001088 denotes mage
T992 5556-5561 UBERON:0002113 denotes rus,
T993 5562-5568 UBERON:0000479 denotes ot hep
T994 5580-5589 GO:0006915 denotes ug induce
T995 5609-5614 NCBITaxon:10239 denotes lso p
T996 5615-5628 BV_19 denotes ay a role Cyt
T997 5665-5670 UBERON:0002113 denotes disea
T998 5692-5700 SP_7 denotes T.bil, L
T999 5707-5712 UBERON:0002113 denotes er in
T1000 5728-5736 SP_7 denotes < 0.001
T1001 5819-5825 UBERON:0002113 denotes otrans
T1002 6052-6056 CHEBI:16199;CHEBI:16199 denotes bin.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
766 5069-5072 Gene denotes CD4 Gene:920
767 5078-5081 Gene denotes CD8 Gene:925
768 5134-5137 Gene denotes AST Gene:26503
769 5191-5195 Gene denotes ACE2 Gene:59272
770 5682-5685 Gene denotes AST Gene:26503
771 5094-5102 Species denotes patients Tax:9606
772 5297-5305 Species denotes Patients Tax:9606
773 5717-5725 Species denotes patients Tax:9606
774 4649-4657 Disease denotes COVID-19 MESH:C000657245
775 4914-4933 Disease denotes Hepatic dysfunction MESH:D008107
776 4975-4988 Disease denotes liver disease MESH:D008107
777 5007-5028 Disease denotes chronic liver disease MESH:D058625
778 5108-5129 Disease denotes hepatic dysfunction N MESH:D008107
779 5311-5330 Disease denotes hepatic dysfunction MESH:D008107
780 5365-5370 Disease denotes fever MESH:D005334
781 5407-5430 Disease denotes Abnormal liver function MESH:D056486
782 5491-5510 Disease denotes Hepatic dysfunction MESH:D008107
783 5599-5603 Disease denotes SIRS
787 1012-1020 Species denotes SARS-CoV Tax:694009
788 1022-1030 Species denotes MERS-CoV Tax:1335626
789 1035-1043 Disease denotes COVID-19 MESH:C000657245
798 5774-5798 Gene denotes alanine aminotransferase Gene:2875
799 5800-5803 Gene denotes AST Gene:26503
800 5861-5869 Species denotes MERS-CoV Tax:1335626
801 5871-5915 Species denotes middle east respiratory syndrome coronavirus Tax:1335626
802 5974-5982 Species denotes SARS-COV Tax:694009
803 5984-6029 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
804 6034-6038 Chemical denotes Bili
805 6046-6055 Chemical denotes bilirubin MESH:D001663
823 765-767 Gene denotes GI Gene:2770
824 570-572 Gene denotes GI Gene:2770
825 176-178 Gene denotes GI Gene:2770
826 137-139 Gene denotes GI Gene:2770
827 37-45 Species denotes SARS-CoV Tax:694009
828 114-122 Species denotes patients Tax:9606
829 276-284 Species denotes Patients Tax:9606
830 451-459 Species denotes patients Tax:9606
831 793-801 Species denotes SARS-CoV Tax:694009
832 916-924 Species denotes patients Tax:9606
833 236-244 Disease denotes diarrhea MESH:D003967
834 304-310 Disease denotes nausea MESH:D009325
835 312-320 Disease denotes vomiting MESH:D014839
836 336-350 Disease denotes abdominal pain MESH:D015746
837 465-473 Disease denotes diarrhea MESH:D003967
838 666-674 Disease denotes diarrhea MESH:D003967
839 698-702 Disease denotes ARDS MESH:D012128

2_test

Id Subject Object Predicate Lexical cue
32620220-14517783-2074110 149-151 14517783 denotes 68
32620220-15836711-2074111 153-155 15836711 denotes 69
32620220-12781535-2074112 157-159 12781535 denotes 70
32620220-15836711-2074113 256-258 15836711 denotes 69
32620220-12781533-2074114 261-263 12781533 denotes 71
32620220-15654797-2074115 363-365 15654797 denotes 72
32620220-14517783-2074116 549-551 14517783 denotes 68
32620220-15836711-2074117 627-629 15836711 denotes 69
32620220-12781535-2074118 745-747 12781535 denotes 70
32620220-15654797-2074119 970-972 15654797 denotes 72