PMC:7212949 / 22124-24029
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T111 | 396-401 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T112 | 429-434 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T113 | 566-571 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T114 | 755-760 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T115 | 771-776 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T116 | 1154-1165 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
| T117 | 1197-1209 | Body_part | denotes | Muscle fiber | http://purl.org/sig/ont/fma/fma67328 |
| T118 | 1683-1688 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T63 | 396-401 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T64 | 429-434 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T65 | 566-571 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T66 | 755-760 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T67 | 771-776 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T68 | 1143-1150 | Body_part | denotes | vessels | http://purl.obolibrary.org/obo/UBERON_0000055 |
| T69 | 1683-1688 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T165 | 0-4 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T166 | 449-452 | Disease | denotes | CHF | http://purl.obolibrary.org/obo/MONDO_0005009 |
| T167 | 491-494 | Disease | denotes | CHF | http://purl.obolibrary.org/obo/MONDO_0005009 |
| T168 | 510-531 | Disease | denotes | Sudden cardiac arrest | http://purl.obolibrary.org/obo/MONDO_0007264 |
| T169 | 517-531 | Disease | denotes | cardiac arrest | http://purl.obolibrary.org/obo/MONDO_0000745 |
| T170 | 540-542 | Disease | denotes | MI | http://purl.obolibrary.org/obo/MONDO_0005068 |
| T171 | 547-557 | Disease | denotes | arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
| T172 | 755-768 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T173 | 914-916 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
| T174 | 998-1000 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
| T175 | 1004-1006 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
| T176 | 1309-1317 | Disease | denotes | Diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T177 | 1448-1452 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T178 | 1552-1558 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T179 | 1716-1718 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
| T180 | 1733-1741 | Disease | denotes | myositis | http://purl.obolibrary.org/obo/MONDO_0008054|http://purl.obolibrary.org/obo/MONDO_0021167 |
| T182 | 1883-1893 | Disease | denotes | arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T189 | 125-127 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
| T190 | 125-127 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
| T191 | 181-184 | http://purl.obolibrary.org/obo/NCBITaxon_9596 | denotes | Pan |
| T192 | 396-401 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T193 | 429-434 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T194 | 566-571 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T195 | 755-760 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T196 | 755-760 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T197 | 755-760 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T198 | 755-760 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T199 | 771-776 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T200 | 879-881 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T201 | 891-893 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T202 | 928-930 | http://purl.obolibrary.org/obo/CLO_0003622 | denotes | Hb |
| T203 | 992-993 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T204 | 1088-1089 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T205 | 1092-1093 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T206 | 1096-1097 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T207 | 1143-1150 | http://purl.obolibrary.org/obo/UBERON_0000055 | denotes | vessels |
| T208 | 1197-1203 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | Muscle |
| T209 | 1197-1203 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | Muscle |
| T210 | 1197-1203 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | Muscle |
| T211 | 1197-1203 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | Muscle |
| T212 | 1218-1219 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T213 | 1683-1688 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T214 | 1683-1688 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T215 | 1683-1688 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T216 | 1683-1688 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T217 | 1694-1699 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T218 | 1790-1792 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T53 | 125-127 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
| T54 | 540-542 | Chemical | denotes | MI | http://purl.obolibrary.org/obo/CHEBI_53620|http://purl.obolibrary.org/obo/CHEBI_74704 |
| T56 | 616-618 | Chemical | denotes | BP | http://purl.obolibrary.org/obo/CHEBI_29865 |
| T57 | 847-849 | Chemical | denotes | Ca | http://purl.obolibrary.org/obo/CHEBI_22984 |
| T58 | 873-875 | Chemical | denotes | Mg | http://purl.obolibrary.org/obo/CHEBI_25107 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T21 | 1028-1032 | http://purl.obolibrary.org/obo/GO_0004111 | denotes | CKMB |
| T22 | 1210-1215 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | lysis |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T137 | 396-406 | Phenotype | denotes | Chest pain | http://purl.obolibrary.org/obo/HP_0100749 |
| T138 | 429-439 | Phenotype | denotes | chest pain | http://purl.obolibrary.org/obo/HP_0100749 |
| T139 | 449-452 | Phenotype | denotes | CHF | http://purl.obolibrary.org/obo/HP_0001635 |
| T140 | 491-494 | Phenotype | denotes | CHF | http://purl.obolibrary.org/obo/HP_0001635 |
| T141 | 510-531 | Phenotype | denotes | Sudden cardiac arrest | http://purl.obolibrary.org/obo/HP_0031628 |
| T142 | 547-557 | Phenotype | denotes | arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |
| T143 | 566-576 | Phenotype | denotes | Chest pain | http://purl.obolibrary.org/obo/HP_0100749 |
| T144 | 721-733 | Phenotype | denotes | cardiomegaly | http://purl.obolibrary.org/obo/HP_0001640 |
| T145 | 755-768 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T146 | 795-807 | Phenotype | denotes | Palpitations | http://purl.obolibrary.org/obo/HP_0001962 |
| T147 | 1119-1124 | Phenotype | denotes | edema | http://purl.obolibrary.org/obo/HP_0000969 |
| T148 | 1487-1496 | Phenotype | denotes | Hypoxemia | http://purl.obolibrary.org/obo/HP_0012418 |
| T149 | 1733-1741 | Phenotype | denotes | myositis | http://purl.obolibrary.org/obo/HP_0100614 |
| T150 | 1835-1846 | Phenotype | denotes | Tachycardia | http://purl.obolibrary.org/obo/HP_0001649 |
| T151 | 1875-1893 | Phenotype | denotes | Cardiac arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T225 | 0-56 | Sentence | denotes | SARS (only studies with large study population included) |
| T226 | 57-375 | Sentence | denotes | Study Booth et al (2003)N = 144, confirmed casesRetrospective study Li et al (2003)N = 46, confirmed casesProspective study Pan et al (2003)N = 15, confirmed casesRetrospective study Ding et al (2004)N = 8 (4 confirmed cases, 4 control)Clinicopathologic study Yu et al (2006)N = 121, confirmed casesRetrospective study |
| T227 | 376-612 | Sentence | denotes | Clinical features • Chest pain (10%)• ↑HR (46%) • No chest pain or overt CHF on admission• ↓HR (non-ICU) ↑HR (ICU)•CHF exacerbation • Sudden cardiac arrest (100%)• MI and arrhythmia (33%) • Chest pain • ↑HR (71.9%) (62.8%, 45.4%, 35.5%) |
| T228 | 613-707 | Sentence | denotes | • ↓BP (50.4%) (28.1%, 21.5%, 14.8% during the first, second, third week)↓HR, transient (14.9%) |
| T229 | 708-768 | Sentence | denotes | • Reversible cardiomegaly (10.7%), no clinical heart failure |
| T230 | 769-792 | Sentence | denotes | • Chest discomfort (7%) |
| T231 | 793-812 | Sentence | denotes | • Palpitations (4%) |
| T232 | 813-857 | Sentence | denotes | Key findings on investigations • ↓Ca++ (60%) |
| T233 | 858-869 | Sentence | denotes | • ↓K+ (26%) |
| T234 | 870-883 | Sentence | denotes | • ↓Mg++ (18%) |
| T235 | 884-895 | Sentence | denotes | • ↓P+ (27%) |
| T236 | 896-916 | Sentence | denotes | • ↑ LDH (87%) • ↑ CK |
| T237 | 917-924 | Sentence | denotes | • ↑ LDH |
| T238 | 925-930 | Sentence | denotes | • ↓Hb |
| T239 | 931-942 | Sentence | denotes | • EKG: RBBB |
| T240 | 943-1000 | Sentence | denotes | • Echo: ↓LVEF • Abnormal cardiac enzymes (66%) N/A • ↑ CK |
| T241 | 1001-1032 | Sentence | denotes | • ↑CK (26%) without TnI or CKMB |
| T242 | 1033-1040 | Sentence | denotes | • ↑ LDH |
| T243 | 1041-1065 | Sentence | denotes | • CXR or CT abnormality: |
| T244 | 1066-1070 | Sentence | denotes | 100% |
| T245 | 1071-1124 | Sentence | denotes | Histopathology N/A N/A N/A • Myocardial stromal edema |
| T246 | 1125-1165 | Sentence | denotes | • Infiltration of vessels by lymphocytes |
| T247 | 1166-1194 | Sentence | denotes | • Focal hyaline degeneration |
| T248 | 1195-1219 | Sentence | denotes | • Muscle fiber lysis N/A |
| T249 | 1220-1270 | Sentence | denotes | Key study findings and message • 20% ICU admission |
| T250 | 1271-1306 | Sentence | denotes | • 6.5% Case fatality rate (21 days) |
| T251 | 1307-1525 | Sentence | denotes | • Diabetes and other comorbidities independently associated with poor prognosis Possibly reversible subclinical diastolic impairment seen in SARS patients Proposed causes of SCD:• Hypoxemia leading to myocardial strain |
| T252 | 1526-1558 | Sentence | denotes | • Direct viral myocardial injury |
| T253 | 1559-1599 | Sentence | denotes | • Stress aggravates pre-existing disease |
| T254 | 1600-1767 | Sentence | denotes | • Sympathetic response causing electrical myocardial instability ACE2 expressed in heart, but virus not detected • ↑CK likely due to myositis as cardiac enzymes normal |
| T255 | 1768-1787 | Sentence | denotes | • 15% ICU admission |
| T256 | 1788-1832 | Sentence | denotes | • 18 (5) days mean duration of hospital stay |
| T257 | 1833-1872 | Sentence | denotes | • Tachycardia persists during follow up |
| T258 | 1873-1905 | Sentence | denotes | • Cardiac arrhythmia is uncommon |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1726 | 240-243 | CHEBI:85129;DG_29;CHEBI:85129 | denotes | Din |
| T1727 | 314-325 | GO:0007567 | denotes | dy Yu et al |
| T1729 | 472-479 | GO:0007565 | denotes | non-ICU |
| T1730 | 543-546 | UBERON:0002113 | denotes | and |
| T1732 | 808-835 | GO:0007565 | denotes | (4%) Key findings on invest |
| T1733 | 1047-1080 | GO:0007567 | denotes | or CT abnormality: 100% Histopath |
| T1735 | 1279-1291 | GO:0042571;GO:0016064 | denotes | ase fatality |
| T1736 | 1292-1296 | GO:0016064 | denotes | rate |
| T1737 | 1396-1414 | GO:0007565 | denotes | reversible subclin |
| T1738 | 1552-1578 | GO:0016265 | denotes | injury • Stress aggravates |
| T1740 | 1733-1767 | UBERON:0001987 | denotes | myositis as cardiac enzymes normal |
| T808 | 94-102 | SP_10 | denotes | irmed ca |
| T809 | 104-112 | SP_9 | denotes | sRetrosp |
| T810 | 117-125 | SP_7 | denotes | e study |
| T811 | 132-137 | SP_10 | denotes | l (20 |
| T812 | 1024-1026 | UBERON:0005409 | denotes | o |
| T813 | 1221-1229 | UBERON:0004908 | denotes | ey study |
| T814 | 1461-1463 | CHEBI:29103;CHEBI:29103 | denotes | P |
| T815 | 1479-1484 | UBERON:0001988 | denotes | f SCD |
| T816 | 1523-1525 | CHEBI:29103;CHEBI:29103 | denotes | in |
| T817 | 1540-1545 | UBERON:0001988 | denotes | myoc |
| T818 | 1556-1561 | NCBITaxon:10239 | denotes | ry • |
| T819 | 1577-1582 | UBERON:0001988 | denotes | s pre |
| T820 | 1631-1633 | CHEBI:29103;CHEBI:29103 | denotes | el |
| T821 | 1738-1743 | NCBITaxon:10239 | denotes | tis a |
| T822 | 1766-1775 | UBERON:0000483;CL:0000066 | denotes | l • 15% I |
| T823 | 1776-1781 | CL:0000066 | denotes | U adm |
| T824 | 1785-1790 | UBERON:0000160 | denotes | on • |
| T825 | 1817-1828 | GO:0005902 | denotes | f hospital |
| T826 | 1837-1842 | NCBITaxon:10239;GO:0006260 | denotes | chyca |
| T827 | 1843-1854 | GO:0006260 | denotes | dia persist |
| T828 | 1858-1868 | UBERON:0000160 | denotes | ring follo |
| T829 | 1885-1890 | NCBITaxon:10239 | denotes | rhyth |