PMC:7210460 / 3344-3636
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T12 | 25-32 | Body_part | denotes | Alanine | http://purl.org/sig/ont/fma/fma82749 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T13 | 203-211 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T41 | 100-108 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T42 | 150-151 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T43 | 191-199 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T38 | 25-32 | Chemical | denotes | Alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T20 | 0-292 | Sentence | denotes | As suggested by authors, Alanine replacements change the enzyme dynamics and increase its catalytic activity by allowing the two domains III to be in a close contact; although, the catalytic activity of SARS-CoV-2 Mpro was only slightly higher with similar Kd of dimer dissociation (~2.5 μM). |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 70 | 214-218 | Gene | denotes | Mpro | Gene:8673700 |
| 81 | 203-213 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 91 | 25-32 | Chemical | denotes | Alanine | MESH:D000409 |