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PMC:7205724 / 4129-4856 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
140 632-635 Gene denotes ACE Gene:1636
141 439-444 Gene denotes furin Gene:5045
142 195-200 Gene denotes furin Gene:5045
143 550-551 Gene denotes S Gene:43740568
144 497-498 Gene denotes S Gene:43740568
145 169-170 Gene denotes S Gene:43740568
146 158-168 Species denotes SARS-CoV 2 Tax:2697049
147 231-236 Species denotes human Tax:9606
148 237-247 Species denotes SARS-CoV 2 Tax:2697049
149 267-272 Species denotes human Tax:9606
150 273-281 Species denotes SARS-CoV Tax:694009
151 297-301 Species denotes CoVs Tax:11118
152 326-329 Species denotes CoV Tax:11118
153 486-496 Species denotes SARS-CoV 2 Tax:2697049
154 539-549 Species denotes SARS-CoV 2 Tax:2697049
155 626-631 Species denotes human Tax:9606
156 662-671 Species denotes SARS-CoV2 Tax:2697049
157 569-575 CellLine denotes VeroE6 CVCL:0574

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T22 79-90 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T23 95-106 Body_part denotes nucleotides http://purl.org/sig/ont/fma/fma82740
T24 576-581 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T25 607-612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T33 158-166 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 237-245 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 273-281 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 287-291 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T37 316-320 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 486-494 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T39 539-547 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 662-666 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T39 44-45 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 132-134 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T41 139-141 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T42 139-141 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T43 183-184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 231-236 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T45 267-272 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T46 283-286 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T47 464-466 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T48 467-469 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T49 467-469 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T50 569-581 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T51 607-612 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T52 626-631 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T53 712-714 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T54 715-717 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T55 715-717 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T23 79-90 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T24 79-84 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T25 85-90 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T26 95-106 Chemical denotes nucleotides http://purl.obolibrary.org/obo/CHEBI_36976
T27 139-141 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T28 467-469 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T29 715-717 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387

LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T4 632-635 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes ACE http://purl.bioontology.org/ontology/MEDDRA/10050289

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T13 210-214 http://purl.obolibrary.org/obo/BFO_0000029 denotes site
T14 454-458 http://purl.obolibrary.org/obo/BFO_0000029 denotes site
T15 576-581 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T16 607-612 http://purl.obolibrary.org/obo/CL_0000000 denotes cells

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 79-90 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T16 95-106 Chemical denotes nucleotides http://purl.obolibrary.org/obo/CHEBI_36976

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T36 158-168 Species denotes SARS-CoV 2 NCBItxid:2697049
T37 231-245 Species denotes human SARS-CoV NCBItxid:694009
T38 267-281 Species denotes human SARS-CoV NCBItxid:694009
T39 283-301 Species denotes bat SARS-like CoVs NCBItxid:1508227
T40 307-315 Species denotes pangolin NCBItxid:9972|NCBItxid:9971
T42 316-329 Species denotes SARS-like CoV NCBItxid:694009
T43 486-496 Species denotes SARS-CoV 2 NCBItxid:2697049
T44 539-549 Species denotes SARS-CoV 2 NCBItxid:2697049
T45 626-631 Species denotes human NCBItxid:9606
T46 662-671 Species denotes SARS-CoV2 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T41 0-171 Sentence denotes As evidenced by sequence analysis, there is a residue insertion formed of four amino acids (12 nucleotides) at the boundary between S1 and S2 subunits of the SARS-CoV 2 S.
T42 172-374 Sentence denotes It defines a polybasic furin cleavage site of RRAR for the human SARS-CoV 2 that was absent in human SARS-CoV, bat SARS-like CoVs, and pangolin SARS-like CoV while might be present in other species [3].
T43 375-525 Sentence denotes After the introduction of mutation to the residue insertion and furin cleavage site, the S1/S2 cleavage of the SARS-CoV 2 S did not longer take place.
T44 526-636 Sentence denotes However, the SARS-CoV 2 S entry raised for VeroE6 cells and remained high in BHK cells that express human ACE.
T45 637-727 Sentence denotes Therefore, it seems that SARS-CoV2 transmissibility does not depend on the S1/S2 cleavage.

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
146 158-168 Species denotes SARS-CoV 2 Tax:2697049
145 169-170 Gene denotes S Gene:43740568
142 195-200 Gene denotes furin Gene:5045
147 231-236 Species denotes human Tax:9606
148 237-247 Species denotes SARS-CoV 2 Tax:2697049
149 267-272 Species denotes human Tax:9606
150 273-281 Species denotes SARS-CoV Tax:694009
151 297-301 Species denotes CoVs Tax:11118
152 326-329 Species denotes CoV Tax:11118
141 439-444 Gene denotes furin Gene:5045
153 486-496 Species denotes SARS-CoV 2 Tax:2697049
144 497-498 Gene denotes S Gene:43740568
154 539-549 Species denotes SARS-CoV 2 Tax:2697049
143 550-551 Gene denotes S Gene:43740568
157 569-575 CellLine denotes VeroE6 CVCL:0574
155 626-631 Species denotes human Tax:9606
140 632-635 Gene denotes ACE Gene:1636
156 662-671 Species denotes SARS-CoV2 Tax:2697049

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T534 195-200 Protein denotes furin https://www.uniprot.org/uniprot/Q9UCZ5|https://www.uniprot.org/uniprot/Q6LBS3|https://www.uniprot.org/uniprot/Q6GTN6|https://www.uniprot.org/uniprot/Q28193|https://www.uniprot.org/uniprot/Q14336|https://www.uniprot.org/uniprot/P23377|https://www.uniprot.org/uniprot/P23188|https://www.uniprot.org/uniprot/P09958
T542 439-444 Protein denotes furin https://www.uniprot.org/uniprot/Q9UCZ5|https://www.uniprot.org/uniprot/Q6LBS3|https://www.uniprot.org/uniprot/Q6GTN6|https://www.uniprot.org/uniprot/Q28193|https://www.uniprot.org/uniprot/Q14336|https://www.uniprot.org/uniprot/P23377|https://www.uniprot.org/uniprot/P23188|https://www.uniprot.org/uniprot/P09958
T550 632-635 Protein denotes ACE https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T663 0-2 IN denotes As
T664 3-12 VBN denotes evidenced
T665 13-15 IN denotes by
T666 16-24 NN denotes sequence
T667 25-33 NN denotes analysis
T668 33-34 -COMMA- denotes ,
T669 35-40 EX denotes there
T670 41-43 VBZ denotes is
T671 44-45 DT denotes a
T672 46-53 NN denotes residue
T673 54-63 NN denotes insertion
T674 64-70 VBN denotes formed
T675 71-73 IN denotes of
T676 74-78 CD denotes four
T677 79-84 NN denotes amino
T678 85-90 NNS denotes acids
T679 91-92 -LRB- denotes (
T680 92-94 CD denotes 12
T681 95-106 NNS denotes nucleotides
T682 106-107 -RRB- denotes )
T683 108-110 IN denotes at
T684 111-114 DT denotes the
T685 115-123 NN denotes boundary
T686 124-131 IN denotes between
T687 132-134 NN denotes S1
T688 135-138 CC denotes and
T689 139-141 NN denotes S2
T690 142-150 NNS denotes subunits
T691 151-153 IN denotes of
T692 154-157 DT denotes the
T693 158-166 NN denotes SARS-CoV
T694 167-168 CD denotes 2
T695 169-171 NNP denotes S.
T696 172-174 PRP denotes It
T697 175-182 VBZ denotes defines
T698 183-184 DT denotes a
T699 185-194 JJ denotes polybasic
T700 195-200 NN denotes furin
T701 201-209 NN denotes cleavage
T702 210-214 NN denotes site
T703 215-217 IN denotes of
T704 218-222 NN denotes RRAR
T705 223-226 IN denotes for
T706 227-230 DT denotes the
T707 231-236 JJ denotes human
T708 237-245 NN denotes SARS-CoV
T709 246-247 CD denotes 2
T710 248-252 WDT denotes that
T711 253-256 VBD denotes was
T712 257-263 JJ denotes absent
T713 264-266 IN denotes in
T714 267-272 JJ denotes human
T715 273-281 NN denotes SARS-CoV
T716 281-282 -COMMA- denotes ,
T717 283-286 NN denotes bat
T718 287-296 JJ denotes SARS-like
T719 297-301 NNS denotes CoVs
T720 301-302 -COMMA- denotes ,
T721 303-306 CC denotes and
T722 307-315 NN denotes pangolin
T723 316-325 JJ denotes SARS-like
T724 326-329 NN denotes CoV
T725 330-335 NN denotes while
T726 336-341 MD denotes might
T727 342-344 VB denotes be
T728 345-352 JJ denotes present
T729 353-355 IN denotes in
T730 356-361 JJ denotes other
T731 362-369 NNS denotes species
T732 370-371 -LRB- denotes [
T733 371-372 CD denotes 3
T734 372-373 -RRB- denotes ]
T735 375-380 IN denotes After
T736 381-384 DT denotes the
T737 385-397 NN denotes introduction
T738 398-400 IN denotes of
T739 401-409 NN denotes mutation
T740 410-412 TO denotes to
T741 413-416 DT denotes the
T742 417-424 NN denotes residue
T743 425-434 NN denotes insertion
T744 435-438 CC denotes and
T745 439-444 NN denotes furin
T746 445-453 NN denotes cleavage
T747 454-458 NN denotes site
T748 458-459 -COMMA- denotes ,
T749 460-463 DT denotes the
T750 464-469 NN denotes S1/S2
T751 470-478 NN denotes cleavage
T752 479-481 IN denotes of
T753 482-485 DT denotes the
T754 486-494 JJ denotes SARS-CoV
T755 495-496 CD denotes 2
T756 497-498 NN denotes S
T757 499-502 VBD denotes did
T758 503-506 RB denotes not
T759 507-513 RBR denotes longer
T760 514-518 VB denotes take
T761 519-524 NN denotes place
T762 526-533 RB denotes However
T763 533-534 -COMMA- denotes ,
T764 535-538 DT denotes the
T765 539-547 JJ denotes SARS-CoV
T766 548-549 CD denotes 2
T767 550-551 NN denotes S
T768 552-557 NN denotes entry
T769 558-564 VBN denotes raised
T770 565-568 IN denotes for
T771 569-575 NN denotes VeroE6
T772 576-581 NNS denotes cells
T773 582-585 CC denotes and
T774 586-594 VBD denotes remained
T775 595-599 JJ denotes high
T776 600-602 IN denotes in
T777 603-606 NN denotes BHK
T778 607-612 NNS denotes cells
T779 613-617 WDT denotes that
T780 618-625 VBP denotes express
T781 626-631 JJ denotes human
T782 632-635 NN denotes ACE
T783 637-646 RB denotes Therefore
T784 646-647 -COMMA- denotes ,
T785 648-650 PRP denotes it
T786 651-656 VBZ denotes seems
T787 657-661 IN denotes that
T788 662-671 NN denotes SARS-CoV2
T789 672-688 NN denotes transmissibility
T790 689-693 VBZ denotes does
T791 694-697 RB denotes not
T792 698-704 VB denotes depend
T793 705-707 IN denotes on
T794 708-711 DT denotes the
T795 712-717 NN denotes S1/S2
T796 718-726 NN denotes cleavage
R770 T768 T774 arg1Of entry,remained
R771 T775 T774 arg2Of high,remained
R772 T768 T775 arg1Of entry,high
R773 T775 T776 arg1Of high,in
R774 T778 T776 arg2Of cells,in
R775 T778 T777 arg1Of cells,BHK
R776 T778 T779 arg1Of cells,that
R777 T778 T780 arg1Of cells,express
R778 T782 T780 arg2Of ACE,express
R779 T782 T781 arg1Of ACE,human
R780 T786 T783 arg1Of seems,Therefore
R781 T786 T784 arg1Of seems,","
R782 T785 T786 arg1Of it,seems
R783 T792 T786 arg2Of depend,seems
R784 T792 T787 arg1Of depend,that
R656 T670 T663 arg1Of is,As
R657 T664 T663 arg2Of evidenced,As
R658 T664 T665 arg1Of evidenced,by
R659 T667 T665 arg2Of analysis,by
R660 T667 T666 arg1Of analysis,sequence
R661 T670 T668 arg1Of is,","
R662 T669 T670 arg1Of there,is
R663 T673 T670 arg2Of insertion,is
R664 T673 T671 arg1Of insertion,a
R665 T673 T672 arg1Of insertion,residue
R666 T673 T674 arg2Of insertion,formed
R667 T674 T675 arg1Of formed,of
R668 T678 T675 arg2Of acids,of
R669 T678 T676 arg1Of acids,four
R670 T678 T677 arg1Of acids,amino
R671 T678 T679 arg1Of acids,(
R672 T681 T679 arg2Of nucleotides,(
R673 T682 T679 arg3Of ),(
R674 T681 T680 arg1Of nucleotides,12
R675 T674 T683 arg1Of formed,at
R676 T685 T683 arg2Of boundary,at
R677 T685 T684 arg1Of boundary,the
R678 T670 T686 arg1Of is,between
R679 T690 T686 arg2Of subunits,between
R680 T690 T687 arg1Of subunits,S1
R681 T687 T688 arg1Of S1,and
R682 T689 T688 arg2Of S2,and
R683 T690 T689 arg1Of subunits,S2
R684 T690 T691 arg1Of subunits,of
R685 T695 T691 arg2Of S.,of
R686 T695 T692 arg1Of S.,the
R687 T695 T693 arg1Of S.,SARS-CoV
R688 T695 T694 arg1Of S.,2
R689 T696 T697 arg1Of It,defines
R690 T695 T697 arg2Of S.,defines
R691 T702 T698 arg1Of site,a
R692 T702 T699 arg1Of site,polybasic
R693 T702 T700 arg1Of site,furin
R694 T702 T701 arg1Of site,cleavage
R695 T702 T703 arg1Of site,of
R696 T704 T703 arg2Of RRAR,of
R697 T702 T705 arg1Of site,for
R698 T708 T705 arg2Of SARS-CoV,for
R699 T708 T706 arg1Of SARS-CoV,the
R700 T708 T707 arg1Of SARS-CoV,human
R701 T708 T709 arg1Of SARS-CoV,2
R702 T702 T710 arg1Of site,that
R703 T702 T711 arg1Of site,was
R704 T712 T711 arg2Of absent,was
R705 T702 T712 arg1Of site,absent
R706 T712 T713 arg1Of absent,in
R707 T721 T713 arg2Of and,in
R708 T715 T714 arg1Of SARS-CoV,human
R709 T715 T716 arg1Of SARS-CoV,","
R710 T719 T716 arg2Of CoVs,","
R711 T719 T717 arg1Of CoVs,bat
R712 T719 T718 arg1Of CoVs,SARS-like
R713 T721 T720 arg1Of and,","
R714 T716 T721 arg1Of ",",and
R715 T725 T721 arg2Of while,and
R716 T725 T722 arg1Of while,pangolin
R717 T725 T723 arg1Of while,SARS-like
R718 T725 T724 arg1Of while,CoV
R719 T702 T726 arg1Of site,might
R720 T727 T726 arg2Of be,might
R721 T690 T726 modOf subunits,might
R722 T702 T727 arg1Of site,be
R723 T728 T727 arg2Of present,be
R724 T702 T728 arg1Of site,present
R725 T728 T729 arg1Of present,in
R726 T731 T729 arg2Of species,in
R727 T731 T730 arg1Of species,other
R728 T727 T732 arg1Of be,[
R729 T733 T732 arg2Of 3,[
R730 T734 T732 arg3Of ],[
R731 T760 T735 arg1Of take,After
R732 T737 T735 arg2Of introduction,After
R733 T737 T736 arg1Of introduction,the
R734 T737 T738 arg1Of introduction,of
R735 T739 T738 arg2Of mutation,of
R736 T737 T740 arg1Of introduction,to
R737 T747 T740 arg2Of site,to
R738 T747 T741 arg1Of site,the
R739 T747 T742 arg1Of site,residue
R740 T747 T743 arg1Of site,insertion
R741 T743 T744 arg1Of insertion,and
R742 T745 T744 arg2Of furin,and
R743 T747 T745 arg1Of site,furin
R744 T747 T746 arg1Of site,cleavage
R745 T760 T748 arg1Of take,","
R746 T751 T749 arg1Of cleavage,the
R747 T751 T750 arg1Of cleavage,S1/S2
R748 T751 T752 arg1Of cleavage,of
R749 T756 T752 arg2Of S,of
R750 T756 T753 arg1Of S,the
R751 T756 T754 arg1Of S,SARS-CoV
R752 T756 T755 arg1Of S,2
R753 T751 T757 arg1Of cleavage,did
R754 T760 T757 arg2Of take,did
R755 T760 T758 arg1Of take,not
R756 T760 T759 arg1Of take,longer
R757 T751 T760 arg1Of cleavage,take
R758 T761 T760 arg2Of place,take
R759 T774 T762 arg1Of remained,However
R760 T774 T763 arg1Of remained,","
R761 T768 T764 arg1Of entry,the
R762 T768 T765 arg1Of entry,SARS-CoV
R763 T768 T766 arg1Of entry,2
R764 T768 T767 arg1Of entry,S
R765 T768 T769 arg2Of entry,raised
R766 T769 T770 arg1Of raised,for
R767 T772 T770 arg2Of cells,for
R768 T772 T771 arg1Of cells,VeroE6
R769 T768 T773 arg1Of entry,and
R785 T789 T788 arg1Of transmissibility,SARS-CoV2
R786 T789 T790 arg1Of transmissibility,does
R787 T792 T790 arg2Of depend,does
R788 T792 T791 arg1Of depend,not
R789 T789 T792 arg1Of transmissibility,depend
R790 T792 T793 arg1Of depend,on
R791 T796 T793 arg2Of cleavage,on
R792 T796 T794 arg1Of cleavage,the
R793 T796 T795 arg1Of cleavage,S1/S2

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T22 79-90 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T23 95-106 Body_part denotes nucleotides http://purl.org/sig/ont/fma/fma82740
T24 576-581 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T25 607-612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T33 158-168 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096
T34 237-247 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096
T35 273-281 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 287-291 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T37 316-320 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 486-496 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096
T39 539-549 Disease denotes SARS-CoV 2 http://purl.obolibrary.org/obo/MONDO_0100096
T40 662-671 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T41 0-171 Sentence denotes As evidenced by sequence analysis, there is a residue insertion formed of four amino acids (12 nucleotides) at the boundary between S1 and S2 subunits of the SARS-CoV 2 S.
T42 172-374 Sentence denotes It defines a polybasic furin cleavage site of RRAR for the human SARS-CoV 2 that was absent in human SARS-CoV, bat SARS-like CoVs, and pangolin SARS-like CoV while might be present in other species [3].
T43 375-525 Sentence denotes After the introduction of mutation to the residue insertion and furin cleavage site, the S1/S2 cleavage of the SARS-CoV 2 S did not longer take place.
T44 526-636 Sentence denotes However, the SARS-CoV 2 S entry raised for VeroE6 cells and remained high in BHK cells that express human ACE.
T45 637-727 Sentence denotes Therefore, it seems that SARS-CoV2 transmissibility does not depend on the S1/S2 cleavage.