PMC:7205724 / 2999-3950
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 109 | 930-939 | Species | denotes | SARS-CoV2 | Tax:2697049 |
| 115 | 177-178 | Gene | denotes | S | Gene:43740568 |
| 116 | 83-92 | Species | denotes | SARS-CoV2 | Tax:2697049 |
| 117 | 170-176 | Species | denotes | SARS-2 | Tax:2697049 |
| 118 | 556-569 | Species | denotes | coronaviruses | Tax:11118 |
| 119 | 133-138 | Gene | denotes | spike | Gene:43740568 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T11 | 50-58 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T12 | 93-97 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T13 | 143-155 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T14 | 378-383 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T15 | 438-456 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
| T16 | 544-551 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T17 | 714-721 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T18 | 877-895 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
| T19 | 904-912 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T20 | 940-944 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T28 | 83-87 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T29 | 170-174 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T30 | 930-934 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T17 | 10-11 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T18 | 93-97 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T19 | 163-168 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T20 | 219-221 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T21 | 226-228 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T22 | 226-228 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T23 | 378-383 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T24 | 447-456 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
| T25 | 475-484 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activates |
| T26 | 605-607 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T27 | 608-610 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T28 | 608-610 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T29 | 611-619 | http://purl.obolibrary.org/obo/UBERON_0007651 | denotes | junction |
| T30 | 631-633 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T31 | 631-633 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T32 | 636-637 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T33 | 671-678 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T34 | 838-840 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T35 | 838-840 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T36 | 886-895 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
| T37 | 940-944 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T13 | 50-58 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T14 | 143-155 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T15 | 226-228 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T16 | 544-551 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T17 | 608-610 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T18 | 631-633 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T19 | 671-678 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T20 | 714-721 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T21 | 838-840 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 93-97 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
| T7 | 163-168 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T8 | 198-208 | http://purl.obolibrary.org/obo/BFO_0000034 | denotes | functional |
| T9 | 378-383 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
| T10 | 594-599 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | sites |
| T11 | 940-944 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T9 | 50-58 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T10 | 143-155 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T11 | 544-551 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T12 | 671-678 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T13 | 714-721 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T31 | 83-92 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
| T32 | 170-176 | Species | denotes | SARS-2 | NCBItxid:2697049 |
| T33 | 930-939 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T30 | 0-104 | Sentence | denotes | Fig. 1 is a schematic illustration of the minimum proteins required to mediate the SARS-CoV2 cell entry. |
| T31 | 105-229 | Sentence | denotes | The trimeric, transmembrane spike (S) glycoprotein of the virus, SARS-2-S, includes two main functional subunits: S1 and S2. |
| T32 | 230-384 | Sentence | denotes | The former, in turn, consists of the four core domains, S1A, S1B, S1C, and S1D, that contribute to the attachment to the surface receptor of target cells. |
| T33 | 385-457 | Sentence | denotes | Then, the latter coordinates the fusion of viral and cellular membranes. |
| T34 | 458-552 | Sentence | denotes | Receptor binding activates proteases that can carry out proteolytic cleavage of the S protein. |
| T35 | 553-683 | Sentence | denotes | In coronaviruses, cleavage occurs at two sites: the S1/S2 junction and at the S2′, a region close to the viral fusion peptide [2]. |
| T36 | 684-896 | Sentence | denotes | Proteolytic cleavage of the S protein causes conformational changes so that they cannot revert to the original structure and profound enough to prime the S2 subunit for the fusion of viral and cellular membranes. |
| T37 | 897-951 | Sentence | denotes | Fig. 1 Proteins required for the SARS-CoV2-cell entry. |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 116 | 83-92 | Species | denotes | SARS-CoV2 | Tax:2697049 |
| 119 | 133-138 | Gene | denotes | spike | Gene:43740568 |
| 117 | 170-176 | Species | denotes | SARS-2 | Tax:2697049 |
| 115 | 177-178 | Gene | denotes | S | Gene:43740568 |
| 118 | 556-569 | Species | denotes | coronaviruses | Tax:11118 |
| 109 | 930-939 | Species | denotes | SARS-CoV2 | Tax:2697049 |
LitCovid-sample-UniProt
| Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
|---|---|---|---|---|---|
| T265 | 139-155 | Protein | denotes | (S) glycoprotein | https://www.uniprot.org/uniprot/Q9QAS2|https://www.uniprot.org/uniprot/Q9QAR5|https://www.uniprot.org/uniprot/Q9QAQ8|https://www.uniprot.org/uniprot/Q9IW04|https://www.uniprot.org/uniprot/Q9IKD1|https://www.uniprot.org/uniprot/Q990M4|https://www.uniprot.org/uniprot/Q990M3|https://www.uniprot.org/uniprot/Q990M2|https://www.uniprot.org/uniprot/Q990M1|https://www.uniprot.org/uniprot/Q91AV1|https://www.uniprot.org/uniprot/Q91A26|https://www.uniprot.org/uniprot/Q8V436|https://www.uniprot.org/uniprot/Q8JSP8|https://www.uniprot.org/uniprot/Q8BB25|https://www.uniprot.org/uniprot/Q86623|https://www.uniprot.org/uniprot/Q85088|https://www.uniprot.org/uniprot/Q85087|https://www.uniprot.org/uniprot/Q80BV6|https://www.uniprot.org/uniprot/Q7TFB1|https://www.uniprot.org/uniprot/Q7TFA2|https://www.uniprot.org/uniprot/Q7TA19|https://www.uniprot.org/uniprot/Q7T6T3|https://www.uniprot.org/uniprot/Q7T696|https://www.uniprot.org/uniprot/Q77NC4|https://www.uniprot.org/uniprot/Q6TNF9|https://www.uniprot.org/uniprot/Q6R1L7|https://www.uniprot.org/uniprot/Q6QU82|https://www.uniprot.org/uniprot/Q6Q1S2|https://www.uniprot.org/uniprot/Q696Q6|https://www.uniprot.org/uniprot/Q66291|https://www.uniprot.org/uniprot/Q66290|https://www.uniprot.org/uniprot/Q66199|https://www.uniprot.org/uniprot/Q66177|https://www.uniprot.org/uniprot/Q66176|https://www.uniprot.org/uniprot/Q66174|https://www.uniprot.org/uniprot/Q65984|https://www.uniprot.org/uniprot/Q5MQD0|https://www.uniprot.org/uniprot/Q5I5X9|https://www.uniprot.org/uniprot/Q5DIY0|https://www.uniprot.org/uniprot/Q5DIX9|https://www.uniprot.org/uniprot/Q5DIX8|https://www.uniprot.org/uniprot/Q5DIX7|https://www.uniprot.org/uniprot/Q52PA3|https://www.uniprot.org/uniprot/Q4ZJS1|https://www.uniprot.org/uniprot/Q4U5G0|https://www.uniprot.org/uniprot/Q3T8J0|https://www.uniprot.org/uniprot/Q3LZX1|https://www.uniprot.org/uniprot/Q3I5J5|https://www.uniprot.org/uniprot/Q14EB0|https://www.uniprot.org/uniprot/Q0ZME7|https://www.uniprot.org/uniprot/Q0Q4F2|https://www.uniprot.org/uniprot/Q0Q475|https://www.uniprot.org/uniprot/Q0Q466|https://www.uniprot.org/uniprot/Q0GNB8|https://www.uniprot.org/uniprot/Q02385|https://www.uniprot.org/uniprot/Q02167|https://www.uniprot.org/uniprot/Q01977|https://www.uniprot.org/uniprot/Q008X4|https://www.uniprot.org/uniprot/P89344|https://www.uniprot.org/uniprot/P89343|https://www.uniprot.org/uniprot/P89342|https://www.uniprot.org/uniprot/P59594|https://www.uniprot.org/uniprot/P36334|https://www.uniprot.org/uniprot/P36300|https://www.uniprot.org/uniprot/P33470|https://www.uniprot.org/uniprot/P30208|https://www.uniprot.org/uniprot/P30207|https://www.uniprot.org/uniprot/P30206|https://www.uniprot.org/uniprot/P30019|https://www.uniprot.org/uniprot/P27655|https://www.uniprot.org/uniprot/P25194|https://www.uniprot.org/uniprot/P25193|https://www.uniprot.org/uniprot/P25192|https://www.uniprot.org/uniprot/P25191|https://www.uniprot.org/uniprot/P25190|https://www.uniprot.org/uniprot/P24413|https://www.uniprot.org/uniprot/P23052|https://www.uniprot.org/uniprot/P22432|https://www.uniprot.org/uniprot/P18450|https://www.uniprot.org/uniprot/P17662|https://www.uniprot.org/uniprot/P15777|https://www.uniprot.org/uniprot/P15423|https://www.uniprot.org/uniprot/P12722|https://www.uniprot.org/uniprot/P12651|https://www.uniprot.org/uniprot/P12650|https://www.uniprot.org/uniprot/P11225|https://www.uniprot.org/uniprot/P11224|https://www.uniprot.org/uniprot/P11223|https://www.uniprot.org/uniprot/P10033|https://www.uniprot.org/uniprot/P0DTC2|https://www.uniprot.org/uniprot/P07946|https://www.uniprot.org/uniprot/P05135|https://www.uniprot.org/uniprot/P05134|https://www.uniprot.org/uniprot/O90304|https://www.uniprot.org/uniprot/O39227|https://www.uniprot.org/uniprot/K9N5Q8|https://www.uniprot.org/uniprot/A3EXG6|https://www.uniprot.org/uniprot/A3EXD0|https://www.uniprot.org/uniprot/A3EX94 |
| T364 | 286-289 | Protein | denotes | S1A | https://www.uniprot.org/uniprot/Q642U2|https://www.uniprot.org/uniprot/P28878|https://www.uniprot.org/uniprot/P02350 |
| T367 | 291-294 | Protein | denotes | S1B | https://www.uniprot.org/uniprot/P47835 |
| T368 | 542-551 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
| T401 | 671-681 | Protein | denotes | peptide [2 | https://www.uniprot.org/uniprot/P15230 |
| T402 | 712-721 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
LitCovid-sample-Enju
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T468 | 0-4 | NNP | denotes | Fig. |
| T469 | 5-6 | CD | denotes | 1 |
| T470 | 7-9 | VBZ | denotes | is |
| T471 | 10-11 | DT | denotes | a |
| T472 | 12-21 | JJ | denotes | schematic |
| T473 | 22-34 | NN | denotes | illustration |
| T474 | 35-37 | IN | denotes | of |
| T475 | 38-41 | DT | denotes | the |
| T476 | 42-49 | JJ | denotes | minimum |
| T477 | 50-58 | NNS | denotes | proteins |
| T478 | 59-67 | VBN | denotes | required |
| T479 | 68-70 | TO | denotes | to |
| T480 | 71-78 | VB | denotes | mediate |
| T481 | 79-82 | DT | denotes | the |
| T482 | 83-92 | NN | denotes | SARS-CoV2 |
| T483 | 93-97 | NN | denotes | cell |
| T484 | 98-103 | NN | denotes | entry |
| T485 | 105-108 | DT | denotes | The |
| T486 | 109-117 | JJ | denotes | trimeric |
| T487 | 117-118 | -COMMA- | denotes | , |
| T488 | 119-132 | JJ | denotes | transmembrane |
| T489 | 133-138 | NN | denotes | spike |
| T490 | 139-140 | -LRB- | denotes | ( |
| T491 | 140-141 | NN | denotes | S |
| T492 | 141-142 | -RRB- | denotes | ) |
| T493 | 143-155 | NN | denotes | glycoprotein |
| T494 | 156-158 | IN | denotes | of |
| T495 | 159-162 | DT | denotes | the |
| T496 | 163-168 | NN | denotes | virus |
| T497 | 168-169 | -COMMA- | denotes | , |
| T498 | 170-178 | NN | denotes | SARS-2-S |
| T499 | 178-179 | -COMMA- | denotes | , |
| T500 | 180-188 | VBZ | denotes | includes |
| T501 | 189-192 | CD | denotes | two |
| T502 | 193-197 | JJ | denotes | main |
| T503 | 198-208 | JJ | denotes | functional |
| T504 | 209-217 | NNS | denotes | subunits |
| T505 | 217-218 | -COLON- | denotes | : |
| T506 | 219-221 | NN | denotes | S1 |
| T507 | 222-225 | CC | denotes | and |
| T508 | 226-228 | NN | denotes | S2 |
| T509 | 230-233 | DT | denotes | The |
| T510 | 234-240 | JJ | denotes | former |
| T511 | 240-241 | -COMMA- | denotes | , |
| T512 | 242-244 | IN | denotes | in |
| T513 | 245-249 | NN | denotes | turn |
| T514 | 249-250 | -COMMA- | denotes | , |
| T515 | 251-259 | VBZ | denotes | consists |
| T516 | 260-262 | IN | denotes | of |
| T517 | 263-266 | DT | denotes | the |
| T518 | 267-271 | CD | denotes | four |
| T519 | 272-276 | NN | denotes | core |
| T520 | 277-284 | NNS | denotes | domains |
| T521 | 284-285 | -COMMA- | denotes | , |
| T522 | 286-289 | NN | denotes | S1A |
| T523 | 289-290 | -COMMA- | denotes | , |
| T524 | 291-294 | NN | denotes | S1B |
| T525 | 294-295 | -COMMA- | denotes | , |
| T526 | 296-299 | NN | denotes | S1C |
| T527 | 299-300 | -COMMA- | denotes | , |
| T528 | 301-304 | CC | denotes | and |
| T529 | 305-308 | NN | denotes | S1D |
| T530 | 308-309 | -COMMA- | denotes | , |
| T531 | 310-314 | WDT | denotes | that |
| T532 | 315-325 | VBP | denotes | contribute |
| T533 | 326-328 | TO | denotes | to |
| T534 | 329-332 | DT | denotes | the |
| T535 | 333-343 | NN | denotes | attachment |
| T536 | 344-346 | TO | denotes | to |
| T537 | 347-350 | DT | denotes | the |
| T538 | 351-358 | NN | denotes | surface |
| T539 | 359-367 | NN | denotes | receptor |
| T540 | 368-370 | IN | denotes | of |
| T541 | 371-377 | NN | denotes | target |
| T542 | 378-383 | NNS | denotes | cells |
| T543 | 385-389 | RB | denotes | Then |
| T544 | 389-390 | -COMMA- | denotes | , |
| T545 | 391-394 | DT | denotes | the |
| T546 | 395-401 | JJ | denotes | latter |
| T547 | 402-413 | VBZ | denotes | coordinates |
| T548 | 414-417 | DT | denotes | the |
| T549 | 418-424 | NN | denotes | fusion |
| T550 | 425-427 | IN | denotes | of |
| T551 | 428-433 | JJ | denotes | viral |
| T552 | 434-437 | CC | denotes | and |
| T553 | 438-446 | JJ | denotes | cellular |
| T554 | 447-456 | NNS | denotes | membranes |
| T555 | 458-466 | NN | denotes | Receptor |
| T556 | 467-474 | NN | denotes | binding |
| T557 | 475-484 | VBZ | denotes | activates |
| T558 | 485-494 | NNS | denotes | proteases |
| T559 | 495-499 | WDT | denotes | that |
| T560 | 500-503 | MD | denotes | can |
| T561 | 504-509 | VB | denotes | carry |
| T562 | 510-513 | RP | denotes | out |
| T563 | 514-525 | JJ | denotes | proteolytic |
| T564 | 526-534 | NN | denotes | cleavage |
| T565 | 535-537 | IN | denotes | of |
| T566 | 538-541 | DT | denotes | the |
| T567 | 542-543 | NN | denotes | S |
| T568 | 544-551 | NN | denotes | protein |
| T569 | 553-555 | IN | denotes | In |
| T570 | 556-569 | NNS | denotes | coronaviruses |
| T571 | 569-570 | -COMMA- | denotes | , |
| T572 | 571-579 | NN | denotes | cleavage |
| T573 | 580-586 | VBZ | denotes | occurs |
| T574 | 587-589 | IN | denotes | at |
| T575 | 590-593 | CD | denotes | two |
| T576 | 594-599 | NNS | denotes | sites |
| T577 | 599-600 | -COLON- | denotes | : |
| T578 | 601-604 | DT | denotes | the |
| T579 | 605-610 | NN | denotes | S1/S2 |
| T580 | 611-619 | NN | denotes | junction |
| T581 | 620-623 | CC | denotes | and |
| T582 | 624-626 | IN | denotes | at |
| T583 | 627-630 | DT | denotes | the |
| T584 | 631-634 | NN | denotes | S2′ |
| T585 | 634-635 | -COMMA- | denotes | , |
| T586 | 636-637 | DT | denotes | a |
| T587 | 638-644 | NN | denotes | region |
| T588 | 645-650 | JJ | denotes | close |
| T589 | 651-653 | TO | denotes | to |
| T590 | 654-657 | DT | denotes | the |
| T591 | 658-663 | JJ | denotes | viral |
| T592 | 664-670 | NN | denotes | fusion |
| T593 | 671-678 | NN | denotes | peptide |
| T594 | 679-680 | -LRB- | denotes | [ |
| T595 | 680-681 | CD | denotes | 2 |
| T596 | 681-682 | -RRB- | denotes | ] |
| T597 | 684-695 | JJ | denotes | Proteolytic |
| T598 | 696-704 | NN | denotes | cleavage |
| T599 | 705-707 | IN | denotes | of |
| T600 | 708-711 | DT | denotes | the |
| T601 | 712-713 | NN | denotes | S |
| T602 | 714-721 | NN | denotes | protein |
| T603 | 722-728 | VBZ | denotes | causes |
| T604 | 729-743 | JJ | denotes | conformational |
| T605 | 744-751 | NNS | denotes | changes |
| T606 | 752-754 | IN | denotes | so |
| T607 | 755-759 | IN | denotes | that |
| T608 | 760-764 | PRP | denotes | they |
| T609 | 765-768 | MD | denotes | can |
| T610 | 768-771 | RB | denotes | not |
| T611 | 772-778 | VB | denotes | revert |
| T612 | 779-781 | TO | denotes | to |
| T613 | 782-785 | DT | denotes | the |
| T614 | 786-794 | JJ | denotes | original |
| T615 | 795-804 | NN | denotes | structure |
| T616 | 805-808 | CC | denotes | and |
| T617 | 809-817 | JJ | denotes | profound |
| T618 | 818-824 | RB | denotes | enough |
| T619 | 825-827 | TO | denotes | to |
| T620 | 828-833 | VB | denotes | prime |
| T621 | 834-837 | DT | denotes | the |
| T622 | 838-840 | NN | denotes | S2 |
| T623 | 841-848 | NN | denotes | subunit |
| T624 | 849-852 | IN | denotes | for |
| T625 | 853-856 | DT | denotes | the |
| T626 | 857-863 | NN | denotes | fusion |
| T627 | 864-866 | IN | denotes | of |
| T628 | 867-872 | JJ | denotes | viral |
| T629 | 873-876 | CC | denotes | and |
| T630 | 877-885 | JJ | denotes | cellular |
| T631 | 886-895 | NNS | denotes | membranes |
| T632 | 897-901 | NNP | denotes | Fig. |
| T633 | 902-903 | CD | denotes | 1 |
| T634 | 904-912 | NNS | denotes | Proteins |
| T635 | 913-921 | VBN | denotes | required |
| T636 | 922-925 | IN | denotes | for |
| T637 | 926-929 | DT | denotes | the |
| T638 | 930-944 | NN | denotes | SARS-CoV2-cell |
| T639 | 945-950 | NN | denotes | entry |
| R522 | T528 | T527 | arg1Of | and,"," |
| R523 | T525 | T528 | arg1Of | ",",and |
| R524 | T529 | T528 | arg2Of | S1D,and |
| R525 | T520 | T530 | arg1Of | domains,"," |
| R526 | T520 | T531 | arg1Of | domains,that |
| R527 | T520 | T532 | arg1Of | domains,contribute |
| R528 | T532 | T533 | arg1Of | contribute,to |
| R529 | T535 | T533 | arg2Of | attachment,to |
| R530 | T535 | T534 | arg1Of | attachment,the |
| R531 | T535 | T536 | arg1Of | attachment,to |
| R532 | T539 | T536 | arg2Of | receptor,to |
| R533 | T539 | T537 | arg1Of | receptor,the |
| R534 | T539 | T538 | arg1Of | receptor,surface |
| R535 | T539 | T540 | arg1Of | receptor,of |
| R536 | T542 | T540 | arg2Of | cells,of |
| R537 | T542 | T541 | arg1Of | cells,target |
| R538 | T547 | T543 | arg1Of | coordinates,Then |
| R539 | T547 | T544 | arg1Of | coordinates,"," |
| R540 | T546 | T545 | arg1Of | latter,the |
| R465 | T468 | T469 | arg1Of | Fig.,1 |
| R466 | T468 | T470 | arg1Of | Fig.,is |
| R467 | T473 | T470 | arg2Of | illustration,is |
| R468 | T473 | T471 | arg1Of | illustration,a |
| R469 | T473 | T472 | arg1Of | illustration,schematic |
| R470 | T473 | T474 | arg1Of | illustration,of |
| R471 | T477 | T474 | arg2Of | proteins,of |
| R472 | T477 | T475 | arg1Of | proteins,the |
| R473 | T477 | T476 | arg1Of | proteins,minimum |
| R474 | T477 | T478 | arg2Of | proteins,required |
| R475 | T480 | T479 | arg1Of | mediate,to |
| R476 | T478 | T479 | modOf | required,to |
| R477 | T484 | T480 | arg2Of | entry,mediate |
| R478 | T484 | T481 | arg1Of | entry,the |
| R479 | T484 | T482 | arg1Of | entry,SARS-CoV2 |
| R480 | T484 | T483 | arg1Of | entry,cell |
| R481 | T493 | T485 | arg1Of | glycoprotein,The |
| R482 | T493 | T486 | arg1Of | glycoprotein,trimeric |
| R483 | T486 | T487 | arg1Of | trimeric,"," |
| R484 | T488 | T487 | arg2Of | transmembrane,"," |
| R485 | T493 | T488 | arg1Of | glycoprotein,transmembrane |
| R486 | T493 | T489 | arg1Of | glycoprotein,spike |
| R487 | T493 | T490 | arg1Of | glycoprotein,( |
| R488 | T491 | T490 | arg2Of | S,( |
| R489 | T492 | T490 | arg3Of | ),( |
| R490 | T493 | T494 | arg1Of | glycoprotein,of |
| R491 | T496 | T494 | arg2Of | virus,of |
| R492 | T496 | T495 | arg1Of | virus,the |
| R493 | T493 | T497 | arg1Of | glycoprotein,"," |
| R494 | T498 | T497 | arg2Of | SARS-2-S,"," |
| R495 | T500 | T499 | arg1Of | includes,"," |
| R496 | T493 | T500 | arg1Of | glycoprotein,includes |
| R497 | T504 | T500 | arg2Of | subunits,includes |
| R498 | T504 | T501 | arg1Of | subunits,two |
| R499 | T504 | T502 | arg1Of | subunits,main |
| R500 | T504 | T503 | arg1Of | subunits,functional |
| R501 | T504 | T505 | arg1Of | subunits,: |
| R502 | T507 | T505 | arg2Of | and,: |
| R503 | T506 | T507 | arg1Of | S1,and |
| R504 | T508 | T507 | arg2Of | S2,and |
| R505 | T510 | T509 | arg1Of | former,The |
| R506 | T515 | T511 | arg1Of | consists,"," |
| R507 | T515 | T512 | arg1Of | consists,in |
| R508 | T513 | T512 | arg2Of | turn,in |
| R509 | T515 | T514 | arg1Of | consists,"," |
| R510 | T510 | T515 | arg1Of | former,consists |
| R511 | T515 | T516 | arg1Of | consists,of |
| R512 | T520 | T516 | arg2Of | domains,of |
| R513 | T520 | T517 | arg1Of | domains,the |
| R514 | T520 | T518 | arg1Of | domains,four |
| R515 | T520 | T519 | arg1Of | domains,core |
| R516 | T520 | T521 | arg1Of | domains,"," |
| R517 | T528 | T521 | arg2Of | and,"," |
| R518 | T522 | T523 | arg1Of | S1A,"," |
| R519 | T524 | T523 | arg2Of | S1B,"," |
| R520 | T523 | T525 | arg1Of | ",","," |
| R521 | T526 | T525 | arg2Of | S1C,"," |
| R541 | T546 | T547 | arg1Of | latter,coordinates |
| R542 | T549 | T547 | arg2Of | fusion,coordinates |
| R543 | T549 | T548 | arg1Of | fusion,the |
| R544 | T549 | T550 | arg1Of | fusion,of |
| R545 | T554 | T550 | arg2Of | membranes,of |
| R546 | T554 | T551 | arg1Of | membranes,viral |
| R547 | T551 | T552 | arg1Of | viral,and |
| R548 | T553 | T552 | arg2Of | cellular,and |
| R549 | T554 | T553 | arg1Of | membranes,cellular |
| R550 | T556 | T555 | arg1Of | binding,Receptor |
| R551 | T556 | T557 | arg1Of | binding,activates |
| R552 | T558 | T557 | arg2Of | proteases,activates |
| R553 | T558 | T559 | arg1Of | proteases,that |
| R554 | T558 | T560 | arg1Of | proteases,can |
| R555 | T561 | T560 | arg2Of | carry,can |
| R556 | T558 | T561 | arg1Of | proteases,carry |
| R557 | T564 | T561 | arg2Of | cleavage,carry |
| R558 | T561 | T562 | arg1Of | carry,out |
| R559 | T564 | T563 | arg1Of | cleavage,proteolytic |
| R560 | T564 | T565 | arg1Of | cleavage,of |
| R561 | T568 | T565 | arg2Of | protein,of |
| R562 | T568 | T566 | arg1Of | protein,the |
| R563 | T568 | T567 | arg1Of | protein,S |
| R564 | T573 | T569 | arg1Of | occurs,In |
| R565 | T570 | T569 | arg2Of | coronaviruses,In |
| R566 | T573 | T571 | arg1Of | occurs,"," |
| R567 | T572 | T573 | arg1Of | cleavage,occurs |
| R568 | T573 | T574 | arg1Of | occurs,at |
| R569 | T576 | T574 | arg2Of | sites,at |
| R570 | T576 | T575 | arg1Of | sites,two |
| R571 | T576 | T577 | arg1Of | sites,: |
| R572 | T580 | T577 | arg2Of | junction,: |
| R573 | T580 | T578 | arg1Of | junction,the |
| R574 | T580 | T579 | arg1Of | junction,S1/S2 |
| R575 | T574 | T581 | arg1Of | at,and |
| R576 | T582 | T581 | arg2Of | at,and |
| R577 | T573 | T582 | arg1Of | occurs,at |
| R578 | T584 | T582 | arg2Of | S2′,at |
| R579 | T584 | T583 | arg1Of | S2′,the |
| R580 | T584 | T585 | arg1Of | S2′,"," |
| R581 | T587 | T585 | arg2Of | region,"," |
| R582 | T587 | T586 | arg1Of | region,a |
| R583 | T587 | T588 | arg1Of | region,close |
| R584 | T588 | T589 | arg1Of | close,to |
| R585 | T593 | T589 | arg2Of | peptide,to |
| R586 | T593 | T590 | arg1Of | peptide,the |
| R587 | T593 | T591 | arg1Of | peptide,viral |
| R588 | T593 | T592 | arg1Of | peptide,fusion |
| R589 | T593 | T594 | arg1Of | peptide,[ |
| R590 | T595 | T594 | arg2Of | 2,[ |
| R591 | T596 | T594 | arg3Of | ],[ |
| R592 | T598 | T597 | arg1Of | cleavage,Proteolytic |
| R593 | T598 | T599 | arg1Of | cleavage,of |
| R594 | T602 | T599 | arg2Of | protein,of |
| R595 | T602 | T600 | arg1Of | protein,the |
| R596 | T602 | T601 | arg1Of | protein,S |
| R597 | T598 | T603 | arg1Of | cleavage,causes |
| R598 | T605 | T603 | arg2Of | changes,causes |
| R599 | T605 | T604 | arg1Of | changes,conformational |
| R600 | T603 | T606 | arg1Of | causes,so |
| R601 | T611 | T606 | arg2Of | revert,so |
| R602 | T606 | T607 | arg1Of | so,that |
| R603 | T608 | T609 | arg1Of | they,can |
| R604 | T611 | T609 | arg2Of | revert,can |
| R605 | T611 | T610 | arg1Of | revert,not |
| R606 | T608 | T611 | arg1Of | they,revert |
| R607 | T611 | T612 | arg1Of | revert,to |
| R608 | T615 | T612 | arg2Of | structure,to |
| R609 | T615 | T613 | arg1Of | structure,the |
| R610 | T615 | T614 | arg1Of | structure,original |
| R611 | T615 | T616 | arg1Of | structure,and |
| R612 | T615 | T617 | arg1Of | structure,profound |
| R613 | T620 | T617 | arg2Of | prime,profound |
| R614 | T617 | T618 | arg1Of | profound,enough |
| R615 | T620 | T619 | arg1Of | prime,to |
| R616 | T623 | T620 | arg2Of | subunit,prime |
| R617 | T623 | T621 | arg1Of | subunit,the |
| R618 | T623 | T622 | arg1Of | subunit,S2 |
| R619 | T623 | T624 | arg1Of | subunit,for |
| R620 | T626 | T624 | arg2Of | fusion,for |
| R621 | T626 | T625 | arg1Of | fusion,the |
| R622 | T626 | T627 | arg1Of | fusion,of |
| R623 | T631 | T627 | arg2Of | membranes,of |
| R624 | T631 | T628 | arg1Of | membranes,viral |
| R625 | T628 | T629 | arg1Of | viral,and |
| R626 | T630 | T629 | arg2Of | cellular,and |
| R627 | T631 | T630 | arg1Of | membranes,cellular |
| R628 | T634 | T632 | arg1Of | Proteins,Fig. |
| R629 | T632 | T633 | arg1Of | Fig.,1 |
| R630 | T634 | T635 | arg2Of | Proteins,required |
| R631 | T635 | T636 | arg1Of | required,for |
| R632 | T639 | T636 | arg2Of | entry,for |
| R633 | T639 | T637 | arg1Of | entry,the |
| R634 | T639 | T638 | arg1Of | entry,SARS-CoV2-cell |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T11 | 50-58 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T12 | 93-97 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T13 | 143-155 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T14 | 378-383 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T15 | 438-456 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
| T16 | 544-551 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T17 | 714-721 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T18 | 877-895 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
| T19 | 904-912 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T20 | 940-944 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T28 | 83-92 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T29 | 170-174 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T30 | 930-939 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T30 | 0-104 | Sentence | denotes | Fig. 1 is a schematic illustration of the minimum proteins required to mediate the SARS-CoV2 cell entry. |
| T31 | 105-229 | Sentence | denotes | The trimeric, transmembrane spike (S) glycoprotein of the virus, SARS-2-S, includes two main functional subunits: S1 and S2. |
| T32 | 230-384 | Sentence | denotes | The former, in turn, consists of the four core domains, S1A, S1B, S1C, and S1D, that contribute to the attachment to the surface receptor of target cells. |
| T33 | 385-457 | Sentence | denotes | Then, the latter coordinates the fusion of viral and cellular membranes. |
| T34 | 458-552 | Sentence | denotes | Receptor binding activates proteases that can carry out proteolytic cleavage of the S protein. |
| T35 | 553-683 | Sentence | denotes | In coronaviruses, cleavage occurs at two sites: the S1/S2 junction and at the S2′, a region close to the viral fusion peptide [2]. |
| T36 | 684-896 | Sentence | denotes | Proteolytic cleavage of the S protein causes conformational changes so that they cannot revert to the original structure and profound enough to prime the S2 subunit for the fusion of viral and cellular membranes. |
| T37 | 897-951 | Sentence | denotes | Fig. 1 Proteins required for the SARS-CoV2-cell entry. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32413736-26935699-48112965 | 680-681 | 26935699 | denotes | 2 |
| T3678 | 680-681 | 26935699 | denotes | 2 |