PMC:7205724 / 2960-3950
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
107 | 3-12 | Species | denotes | SARS-CoV2 | Tax:2697049 |
109 | 969-978 | Species | denotes | SARS-CoV2 | Tax:2697049 |
115 | 216-217 | Gene | denotes | S | Gene:43740568 |
116 | 122-131 | Species | denotes | SARS-CoV2 | Tax:2697049 |
117 | 209-215 | Species | denotes | SARS-2 | Tax:2697049 |
118 | 595-608 | Species | denotes | coronaviruses | Tax:11118 |
119 | 172-177 | Gene | denotes | spike | Gene:43740568 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T10 | 13-17 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T11 | 89-97 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T12 | 132-136 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T13 | 182-194 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T14 | 417-422 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T15 | 477-495 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
T16 | 583-590 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T17 | 753-760 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T18 | 916-934 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
T19 | 943-951 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
T20 | 979-983 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T27 | 3-7 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T28 | 122-126 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T29 | 209-213 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T30 | 969-973 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16 | 13-17 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T17 | 49-50 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T18 | 132-136 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T19 | 202-207 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T20 | 258-260 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T21 | 265-267 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T22 | 265-267 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T23 | 417-422 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T24 | 486-495 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
T25 | 514-523 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activates |
T26 | 644-646 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T27 | 647-649 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T28 | 647-649 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T29 | 650-658 | http://purl.obolibrary.org/obo/UBERON_0007651 | denotes | junction |
T30 | 670-672 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T31 | 670-672 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T32 | 675-676 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T33 | 710-717 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T34 | 877-879 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T35 | 877-879 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T36 | 925-934 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
T37 | 979-983 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T13 | 89-97 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T14 | 182-194 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T15 | 265-267 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T16 | 583-590 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T17 | 647-649 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T18 | 670-672 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T19 | 710-717 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T20 | 753-760 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T21 | 877-879 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 13-17 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
T6 | 132-136 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
T7 | 202-207 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T8 | 237-247 | http://purl.obolibrary.org/obo/BFO_0000034 | denotes | functional |
T9 | 417-422 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T10 | 633-638 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | sites |
T11 | 979-983 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T9 | 89-97 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T10 | 182-194 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T11 | 583-590 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T12 | 710-717 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T13 | 753-760 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T30 | 3-12 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T31 | 122-131 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
T32 | 209-215 | Species | denotes | SARS-2 | NCBItxid:2697049 |
T33 | 969-978 | Species | denotes | SARS-CoV2 | NCBItxid:2697049 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T29 | 0-38 | Sentence | denotes | 2 SARS-CoV2 cell entry is not complex |
T30 | 39-143 | Sentence | denotes | Fig. 1 is a schematic illustration of the minimum proteins required to mediate the SARS-CoV2 cell entry. |
T31 | 144-268 | Sentence | denotes | The trimeric, transmembrane spike (S) glycoprotein of the virus, SARS-2-S, includes two main functional subunits: S1 and S2. |
T32 | 269-423 | Sentence | denotes | The former, in turn, consists of the four core domains, S1A, S1B, S1C, and S1D, that contribute to the attachment to the surface receptor of target cells. |
T33 | 424-496 | Sentence | denotes | Then, the latter coordinates the fusion of viral and cellular membranes. |
T34 | 497-591 | Sentence | denotes | Receptor binding activates proteases that can carry out proteolytic cleavage of the S protein. |
T35 | 592-722 | Sentence | denotes | In coronaviruses, cleavage occurs at two sites: the S1/S2 junction and at the S2′, a region close to the viral fusion peptide [2]. |
T36 | 723-935 | Sentence | denotes | Proteolytic cleavage of the S protein causes conformational changes so that they cannot revert to the original structure and profound enough to prime the S2 subunit for the fusion of viral and cellular membranes. |
T37 | 936-990 | Sentence | denotes | Fig. 1 Proteins required for the SARS-CoV2-cell entry. |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
107 | 3-12 | Species | denotes | SARS-CoV2 | Tax:2697049 |
116 | 122-131 | Species | denotes | SARS-CoV2 | Tax:2697049 |
119 | 172-177 | Gene | denotes | spike | Gene:43740568 |
117 | 209-215 | Species | denotes | SARS-2 | Tax:2697049 |
115 | 216-217 | Gene | denotes | S | Gene:43740568 |
118 | 595-608 | Species | denotes | coronaviruses | Tax:11118 |
109 | 969-978 | Species | denotes | SARS-CoV2 | Tax:2697049 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T265 | 178-194 | Protein | denotes | (S) glycoprotein | https://www.uniprot.org/uniprot/Q9QAS2|https://www.uniprot.org/uniprot/Q9QAR5|https://www.uniprot.org/uniprot/Q9QAQ8|https://www.uniprot.org/uniprot/Q9IW04|https://www.uniprot.org/uniprot/Q9IKD1|https://www.uniprot.org/uniprot/Q990M4|https://www.uniprot.org/uniprot/Q990M3|https://www.uniprot.org/uniprot/Q990M2|https://www.uniprot.org/uniprot/Q990M1|https://www.uniprot.org/uniprot/Q91AV1|https://www.uniprot.org/uniprot/Q91A26|https://www.uniprot.org/uniprot/Q8V436|https://www.uniprot.org/uniprot/Q8JSP8|https://www.uniprot.org/uniprot/Q8BB25|https://www.uniprot.org/uniprot/Q86623|https://www.uniprot.org/uniprot/Q85088|https://www.uniprot.org/uniprot/Q85087|https://www.uniprot.org/uniprot/Q80BV6|https://www.uniprot.org/uniprot/Q7TFB1|https://www.uniprot.org/uniprot/Q7TFA2|https://www.uniprot.org/uniprot/Q7TA19|https://www.uniprot.org/uniprot/Q7T6T3|https://www.uniprot.org/uniprot/Q7T696|https://www.uniprot.org/uniprot/Q77NC4|https://www.uniprot.org/uniprot/Q6TNF9|https://www.uniprot.org/uniprot/Q6R1L7|https://www.uniprot.org/uniprot/Q6QU82|https://www.uniprot.org/uniprot/Q6Q1S2|https://www.uniprot.org/uniprot/Q696Q6|https://www.uniprot.org/uniprot/Q66291|https://www.uniprot.org/uniprot/Q66290|https://www.uniprot.org/uniprot/Q66199|https://www.uniprot.org/uniprot/Q66177|https://www.uniprot.org/uniprot/Q66176|https://www.uniprot.org/uniprot/Q66174|https://www.uniprot.org/uniprot/Q65984|https://www.uniprot.org/uniprot/Q5MQD0|https://www.uniprot.org/uniprot/Q5I5X9|https://www.uniprot.org/uniprot/Q5DIY0|https://www.uniprot.org/uniprot/Q5DIX9|https://www.uniprot.org/uniprot/Q5DIX8|https://www.uniprot.org/uniprot/Q5DIX7|https://www.uniprot.org/uniprot/Q52PA3|https://www.uniprot.org/uniprot/Q4ZJS1|https://www.uniprot.org/uniprot/Q4U5G0|https://www.uniprot.org/uniprot/Q3T8J0|https://www.uniprot.org/uniprot/Q3LZX1|https://www.uniprot.org/uniprot/Q3I5J5|https://www.uniprot.org/uniprot/Q14EB0|https://www.uniprot.org/uniprot/Q0ZME7|https://www.uniprot.org/uniprot/Q0Q4F2|https://www.uniprot.org/uniprot/Q0Q475|https://www.uniprot.org/uniprot/Q0Q466|https://www.uniprot.org/uniprot/Q0GNB8|https://www.uniprot.org/uniprot/Q02385|https://www.uniprot.org/uniprot/Q02167|https://www.uniprot.org/uniprot/Q01977|https://www.uniprot.org/uniprot/Q008X4|https://www.uniprot.org/uniprot/P89344|https://www.uniprot.org/uniprot/P89343|https://www.uniprot.org/uniprot/P89342|https://www.uniprot.org/uniprot/P59594|https://www.uniprot.org/uniprot/P36334|https://www.uniprot.org/uniprot/P36300|https://www.uniprot.org/uniprot/P33470|https://www.uniprot.org/uniprot/P30208|https://www.uniprot.org/uniprot/P30207|https://www.uniprot.org/uniprot/P30206|https://www.uniprot.org/uniprot/P30019|https://www.uniprot.org/uniprot/P27655|https://www.uniprot.org/uniprot/P25194|https://www.uniprot.org/uniprot/P25193|https://www.uniprot.org/uniprot/P25192|https://www.uniprot.org/uniprot/P25191|https://www.uniprot.org/uniprot/P25190|https://www.uniprot.org/uniprot/P24413|https://www.uniprot.org/uniprot/P23052|https://www.uniprot.org/uniprot/P22432|https://www.uniprot.org/uniprot/P18450|https://www.uniprot.org/uniprot/P17662|https://www.uniprot.org/uniprot/P15777|https://www.uniprot.org/uniprot/P15423|https://www.uniprot.org/uniprot/P12722|https://www.uniprot.org/uniprot/P12651|https://www.uniprot.org/uniprot/P12650|https://www.uniprot.org/uniprot/P11225|https://www.uniprot.org/uniprot/P11224|https://www.uniprot.org/uniprot/P11223|https://www.uniprot.org/uniprot/P10033|https://www.uniprot.org/uniprot/P0DTC2|https://www.uniprot.org/uniprot/P07946|https://www.uniprot.org/uniprot/P05135|https://www.uniprot.org/uniprot/P05134|https://www.uniprot.org/uniprot/O90304|https://www.uniprot.org/uniprot/O39227|https://www.uniprot.org/uniprot/K9N5Q8|https://www.uniprot.org/uniprot/A3EXG6|https://www.uniprot.org/uniprot/A3EXD0|https://www.uniprot.org/uniprot/A3EX94 |
T364 | 325-328 | Protein | denotes | S1A | https://www.uniprot.org/uniprot/Q642U2|https://www.uniprot.org/uniprot/P28878|https://www.uniprot.org/uniprot/P02350 |
T367 | 330-333 | Protein | denotes | S1B | https://www.uniprot.org/uniprot/P47835 |
T368 | 581-590 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
T401 | 710-720 | Protein | denotes | peptide [2 | https://www.uniprot.org/uniprot/P15230 |
T402 | 751-760 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T461 | 0-1 | CD | denotes | 2 |
T462 | 3-12 | NN | denotes | SARS-CoV2 |
T463 | 13-17 | NN | denotes | cell |
T464 | 18-23 | NN | denotes | entry |
T465 | 24-26 | VBZ | denotes | is |
T466 | 27-30 | RB | denotes | not |
T467 | 31-38 | JJ | denotes | complex |
T468 | 39-43 | NNP | denotes | Fig. |
T469 | 44-45 | CD | denotes | 1 |
T470 | 46-48 | VBZ | denotes | is |
T471 | 49-50 | DT | denotes | a |
T472 | 51-60 | JJ | denotes | schematic |
T473 | 61-73 | NN | denotes | illustration |
T474 | 74-76 | IN | denotes | of |
T475 | 77-80 | DT | denotes | the |
T476 | 81-88 | JJ | denotes | minimum |
T477 | 89-97 | NNS | denotes | proteins |
T478 | 98-106 | VBN | denotes | required |
T479 | 107-109 | TO | denotes | to |
T480 | 110-117 | VB | denotes | mediate |
T481 | 118-121 | DT | denotes | the |
T482 | 122-131 | NN | denotes | SARS-CoV2 |
T483 | 132-136 | NN | denotes | cell |
T484 | 137-142 | NN | denotes | entry |
T485 | 144-147 | DT | denotes | The |
T486 | 148-156 | JJ | denotes | trimeric |
T487 | 156-157 | -COMMA- | denotes | , |
T488 | 158-171 | JJ | denotes | transmembrane |
T489 | 172-177 | NN | denotes | spike |
T490 | 178-179 | -LRB- | denotes | ( |
T491 | 179-180 | NN | denotes | S |
T492 | 180-181 | -RRB- | denotes | ) |
T493 | 182-194 | NN | denotes | glycoprotein |
T494 | 195-197 | IN | denotes | of |
T495 | 198-201 | DT | denotes | the |
T496 | 202-207 | NN | denotes | virus |
T497 | 207-208 | -COMMA- | denotes | , |
T498 | 209-217 | NN | denotes | SARS-2-S |
T499 | 217-218 | -COMMA- | denotes | , |
T500 | 219-227 | VBZ | denotes | includes |
T501 | 228-231 | CD | denotes | two |
T502 | 232-236 | JJ | denotes | main |
T503 | 237-247 | JJ | denotes | functional |
T504 | 248-256 | NNS | denotes | subunits |
T505 | 256-257 | -COLON- | denotes | : |
T506 | 258-260 | NN | denotes | S1 |
T507 | 261-264 | CC | denotes | and |
T508 | 265-267 | NN | denotes | S2 |
T509 | 269-272 | DT | denotes | The |
T510 | 273-279 | JJ | denotes | former |
T511 | 279-280 | -COMMA- | denotes | , |
T512 | 281-283 | IN | denotes | in |
T513 | 284-288 | NN | denotes | turn |
T514 | 288-289 | -COMMA- | denotes | , |
T515 | 290-298 | VBZ | denotes | consists |
T516 | 299-301 | IN | denotes | of |
T517 | 302-305 | DT | denotes | the |
T518 | 306-310 | CD | denotes | four |
T519 | 311-315 | NN | denotes | core |
T520 | 316-323 | NNS | denotes | domains |
T521 | 323-324 | -COMMA- | denotes | , |
T522 | 325-328 | NN | denotes | S1A |
T523 | 328-329 | -COMMA- | denotes | , |
T524 | 330-333 | NN | denotes | S1B |
T525 | 333-334 | -COMMA- | denotes | , |
T526 | 335-338 | NN | denotes | S1C |
T527 | 338-339 | -COMMA- | denotes | , |
T528 | 340-343 | CC | denotes | and |
T529 | 344-347 | NN | denotes | S1D |
T530 | 347-348 | -COMMA- | denotes | , |
T531 | 349-353 | WDT | denotes | that |
T532 | 354-364 | VBP | denotes | contribute |
T533 | 365-367 | TO | denotes | to |
T534 | 368-371 | DT | denotes | the |
T535 | 372-382 | NN | denotes | attachment |
T536 | 383-385 | TO | denotes | to |
T537 | 386-389 | DT | denotes | the |
T538 | 390-397 | NN | denotes | surface |
T539 | 398-406 | NN | denotes | receptor |
T540 | 407-409 | IN | denotes | of |
T541 | 410-416 | NN | denotes | target |
T542 | 417-422 | NNS | denotes | cells |
T543 | 424-428 | RB | denotes | Then |
T544 | 428-429 | -COMMA- | denotes | , |
T545 | 430-433 | DT | denotes | the |
T546 | 434-440 | JJ | denotes | latter |
T547 | 441-452 | VBZ | denotes | coordinates |
T548 | 453-456 | DT | denotes | the |
T549 | 457-463 | NN | denotes | fusion |
T550 | 464-466 | IN | denotes | of |
T551 | 467-472 | JJ | denotes | viral |
T552 | 473-476 | CC | denotes | and |
T553 | 477-485 | JJ | denotes | cellular |
T554 | 486-495 | NNS | denotes | membranes |
T555 | 497-505 | NN | denotes | Receptor |
T556 | 506-513 | NN | denotes | binding |
T557 | 514-523 | VBZ | denotes | activates |
T558 | 524-533 | NNS | denotes | proteases |
T559 | 534-538 | WDT | denotes | that |
T560 | 539-542 | MD | denotes | can |
T561 | 543-548 | VB | denotes | carry |
T562 | 549-552 | RP | denotes | out |
T563 | 553-564 | JJ | denotes | proteolytic |
T564 | 565-573 | NN | denotes | cleavage |
T565 | 574-576 | IN | denotes | of |
T566 | 577-580 | DT | denotes | the |
T567 | 581-582 | NN | denotes | S |
T568 | 583-590 | NN | denotes | protein |
T569 | 592-594 | IN | denotes | In |
T570 | 595-608 | NNS | denotes | coronaviruses |
T571 | 608-609 | -COMMA- | denotes | , |
T572 | 610-618 | NN | denotes | cleavage |
T573 | 619-625 | VBZ | denotes | occurs |
T574 | 626-628 | IN | denotes | at |
T575 | 629-632 | CD | denotes | two |
T576 | 633-638 | NNS | denotes | sites |
T577 | 638-639 | -COLON- | denotes | : |
T578 | 640-643 | DT | denotes | the |
T579 | 644-649 | NN | denotes | S1/S2 |
T580 | 650-658 | NN | denotes | junction |
T581 | 659-662 | CC | denotes | and |
T582 | 663-665 | IN | denotes | at |
T583 | 666-669 | DT | denotes | the |
T584 | 670-673 | NN | denotes | S2′ |
T585 | 673-674 | -COMMA- | denotes | , |
T586 | 675-676 | DT | denotes | a |
T587 | 677-683 | NN | denotes | region |
T588 | 684-689 | JJ | denotes | close |
T589 | 690-692 | TO | denotes | to |
T590 | 693-696 | DT | denotes | the |
T591 | 697-702 | JJ | denotes | viral |
T592 | 703-709 | NN | denotes | fusion |
T593 | 710-717 | NN | denotes | peptide |
T594 | 718-719 | -LRB- | denotes | [ |
T595 | 719-720 | CD | denotes | 2 |
T596 | 720-721 | -RRB- | denotes | ] |
T597 | 723-734 | JJ | denotes | Proteolytic |
T598 | 735-743 | NN | denotes | cleavage |
T599 | 744-746 | IN | denotes | of |
T600 | 747-750 | DT | denotes | the |
T601 | 751-752 | NN | denotes | S |
T602 | 753-760 | NN | denotes | protein |
T603 | 761-767 | VBZ | denotes | causes |
T604 | 768-782 | JJ | denotes | conformational |
T605 | 783-790 | NNS | denotes | changes |
T606 | 791-793 | IN | denotes | so |
T607 | 794-798 | IN | denotes | that |
T608 | 799-803 | PRP | denotes | they |
T609 | 804-807 | MD | denotes | can |
T610 | 807-810 | RB | denotes | not |
T611 | 811-817 | VB | denotes | revert |
T612 | 818-820 | TO | denotes | to |
T613 | 821-824 | DT | denotes | the |
T614 | 825-833 | JJ | denotes | original |
T615 | 834-843 | NN | denotes | structure |
T616 | 844-847 | CC | denotes | and |
T617 | 848-856 | JJ | denotes | profound |
T618 | 857-863 | RB | denotes | enough |
T619 | 864-866 | TO | denotes | to |
T620 | 867-872 | VB | denotes | prime |
T621 | 873-876 | DT | denotes | the |
T622 | 877-879 | NN | denotes | S2 |
T623 | 880-887 | NN | denotes | subunit |
T624 | 888-891 | IN | denotes | for |
T625 | 892-895 | DT | denotes | the |
T626 | 896-902 | NN | denotes | fusion |
T627 | 903-905 | IN | denotes | of |
T628 | 906-911 | JJ | denotes | viral |
T629 | 912-915 | CC | denotes | and |
T630 | 916-924 | JJ | denotes | cellular |
T631 | 925-934 | NNS | denotes | membranes |
T632 | 936-940 | NNP | denotes | Fig. |
T633 | 941-942 | CD | denotes | 1 |
T634 | 943-951 | NNS | denotes | Proteins |
T635 | 952-960 | VBN | denotes | required |
T636 | 961-964 | IN | denotes | for |
T637 | 965-968 | DT | denotes | the |
T638 | 969-983 | NN | denotes | SARS-CoV2-cell |
T639 | 984-989 | NN | denotes | entry |
R458 | T464 | T461 | arg1Of | entry,2 |
R459 | T464 | T462 | arg1Of | entry,SARS-CoV2 |
R460 | T464 | T463 | arg1Of | entry,cell |
R461 | T464 | T465 | arg1Of | entry,is |
R462 | T467 | T465 | arg2Of | complex,is |
R463 | T465 | T466 | arg1Of | is,not |
R464 | T464 | T467 | arg1Of | entry,complex |
R522 | T528 | T527 | arg1Of | and,"," |
R523 | T525 | T528 | arg1Of | ",",and |
R524 | T529 | T528 | arg2Of | S1D,and |
R525 | T520 | T530 | arg1Of | domains,"," |
R526 | T520 | T531 | arg1Of | domains,that |
R527 | T520 | T532 | arg1Of | domains,contribute |
R528 | T532 | T533 | arg1Of | contribute,to |
R529 | T535 | T533 | arg2Of | attachment,to |
R530 | T535 | T534 | arg1Of | attachment,the |
R531 | T535 | T536 | arg1Of | attachment,to |
R532 | T539 | T536 | arg2Of | receptor,to |
R533 | T539 | T537 | arg1Of | receptor,the |
R534 | T539 | T538 | arg1Of | receptor,surface |
R535 | T539 | T540 | arg1Of | receptor,of |
R536 | T542 | T540 | arg2Of | cells,of |
R537 | T542 | T541 | arg1Of | cells,target |
R538 | T547 | T543 | arg1Of | coordinates,Then |
R539 | T547 | T544 | arg1Of | coordinates,"," |
R540 | T546 | T545 | arg1Of | latter,the |
R465 | T468 | T469 | arg1Of | Fig.,1 |
R466 | T468 | T470 | arg1Of | Fig.,is |
R467 | T473 | T470 | arg2Of | illustration,is |
R468 | T473 | T471 | arg1Of | illustration,a |
R469 | T473 | T472 | arg1Of | illustration,schematic |
R470 | T473 | T474 | arg1Of | illustration,of |
R471 | T477 | T474 | arg2Of | proteins,of |
R472 | T477 | T475 | arg1Of | proteins,the |
R473 | T477 | T476 | arg1Of | proteins,minimum |
R474 | T477 | T478 | arg2Of | proteins,required |
R475 | T480 | T479 | arg1Of | mediate,to |
R476 | T478 | T479 | modOf | required,to |
R477 | T484 | T480 | arg2Of | entry,mediate |
R478 | T484 | T481 | arg1Of | entry,the |
R479 | T484 | T482 | arg1Of | entry,SARS-CoV2 |
R480 | T484 | T483 | arg1Of | entry,cell |
R481 | T493 | T485 | arg1Of | glycoprotein,The |
R482 | T493 | T486 | arg1Of | glycoprotein,trimeric |
R483 | T486 | T487 | arg1Of | trimeric,"," |
R484 | T488 | T487 | arg2Of | transmembrane,"," |
R485 | T493 | T488 | arg1Of | glycoprotein,transmembrane |
R486 | T493 | T489 | arg1Of | glycoprotein,spike |
R487 | T493 | T490 | arg1Of | glycoprotein,( |
R488 | T491 | T490 | arg2Of | S,( |
R489 | T492 | T490 | arg3Of | ),( |
R490 | T493 | T494 | arg1Of | glycoprotein,of |
R491 | T496 | T494 | arg2Of | virus,of |
R492 | T496 | T495 | arg1Of | virus,the |
R493 | T493 | T497 | arg1Of | glycoprotein,"," |
R494 | T498 | T497 | arg2Of | SARS-2-S,"," |
R495 | T500 | T499 | arg1Of | includes,"," |
R496 | T493 | T500 | arg1Of | glycoprotein,includes |
R497 | T504 | T500 | arg2Of | subunits,includes |
R498 | T504 | T501 | arg1Of | subunits,two |
R499 | T504 | T502 | arg1Of | subunits,main |
R500 | T504 | T503 | arg1Of | subunits,functional |
R501 | T504 | T505 | arg1Of | subunits,: |
R502 | T507 | T505 | arg2Of | and,: |
R503 | T506 | T507 | arg1Of | S1,and |
R504 | T508 | T507 | arg2Of | S2,and |
R505 | T510 | T509 | arg1Of | former,The |
R506 | T515 | T511 | arg1Of | consists,"," |
R507 | T515 | T512 | arg1Of | consists,in |
R508 | T513 | T512 | arg2Of | turn,in |
R509 | T515 | T514 | arg1Of | consists,"," |
R510 | T510 | T515 | arg1Of | former,consists |
R511 | T515 | T516 | arg1Of | consists,of |
R512 | T520 | T516 | arg2Of | domains,of |
R513 | T520 | T517 | arg1Of | domains,the |
R514 | T520 | T518 | arg1Of | domains,four |
R515 | T520 | T519 | arg1Of | domains,core |
R516 | T520 | T521 | arg1Of | domains,"," |
R517 | T528 | T521 | arg2Of | and,"," |
R518 | T522 | T523 | arg1Of | S1A,"," |
R519 | T524 | T523 | arg2Of | S1B,"," |
R520 | T523 | T525 | arg1Of | ",","," |
R521 | T526 | T525 | arg2Of | S1C,"," |
R541 | T546 | T547 | arg1Of | latter,coordinates |
R542 | T549 | T547 | arg2Of | fusion,coordinates |
R543 | T549 | T548 | arg1Of | fusion,the |
R544 | T549 | T550 | arg1Of | fusion,of |
R545 | T554 | T550 | arg2Of | membranes,of |
R546 | T554 | T551 | arg1Of | membranes,viral |
R547 | T551 | T552 | arg1Of | viral,and |
R548 | T553 | T552 | arg2Of | cellular,and |
R549 | T554 | T553 | arg1Of | membranes,cellular |
R550 | T556 | T555 | arg1Of | binding,Receptor |
R551 | T556 | T557 | arg1Of | binding,activates |
R552 | T558 | T557 | arg2Of | proteases,activates |
R553 | T558 | T559 | arg1Of | proteases,that |
R554 | T558 | T560 | arg1Of | proteases,can |
R555 | T561 | T560 | arg2Of | carry,can |
R556 | T558 | T561 | arg1Of | proteases,carry |
R557 | T564 | T561 | arg2Of | cleavage,carry |
R558 | T561 | T562 | arg1Of | carry,out |
R559 | T564 | T563 | arg1Of | cleavage,proteolytic |
R560 | T564 | T565 | arg1Of | cleavage,of |
R561 | T568 | T565 | arg2Of | protein,of |
R562 | T568 | T566 | arg1Of | protein,the |
R563 | T568 | T567 | arg1Of | protein,S |
R564 | T573 | T569 | arg1Of | occurs,In |
R565 | T570 | T569 | arg2Of | coronaviruses,In |
R566 | T573 | T571 | arg1Of | occurs,"," |
R567 | T572 | T573 | arg1Of | cleavage,occurs |
R568 | T573 | T574 | arg1Of | occurs,at |
R569 | T576 | T574 | arg2Of | sites,at |
R570 | T576 | T575 | arg1Of | sites,two |
R571 | T576 | T577 | arg1Of | sites,: |
R572 | T580 | T577 | arg2Of | junction,: |
R573 | T580 | T578 | arg1Of | junction,the |
R574 | T580 | T579 | arg1Of | junction,S1/S2 |
R575 | T574 | T581 | arg1Of | at,and |
R576 | T582 | T581 | arg2Of | at,and |
R577 | T573 | T582 | arg1Of | occurs,at |
R578 | T584 | T582 | arg2Of | S2′,at |
R579 | T584 | T583 | arg1Of | S2′,the |
R580 | T584 | T585 | arg1Of | S2′,"," |
R581 | T587 | T585 | arg2Of | region,"," |
R582 | T587 | T586 | arg1Of | region,a |
R583 | T587 | T588 | arg1Of | region,close |
R584 | T588 | T589 | arg1Of | close,to |
R585 | T593 | T589 | arg2Of | peptide,to |
R586 | T593 | T590 | arg1Of | peptide,the |
R587 | T593 | T591 | arg1Of | peptide,viral |
R588 | T593 | T592 | arg1Of | peptide,fusion |
R589 | T593 | T594 | arg1Of | peptide,[ |
R590 | T595 | T594 | arg2Of | 2,[ |
R591 | T596 | T594 | arg3Of | ],[ |
R592 | T598 | T597 | arg1Of | cleavage,Proteolytic |
R593 | T598 | T599 | arg1Of | cleavage,of |
R594 | T602 | T599 | arg2Of | protein,of |
R595 | T602 | T600 | arg1Of | protein,the |
R596 | T602 | T601 | arg1Of | protein,S |
R597 | T598 | T603 | arg1Of | cleavage,causes |
R598 | T605 | T603 | arg2Of | changes,causes |
R599 | T605 | T604 | arg1Of | changes,conformational |
R600 | T603 | T606 | arg1Of | causes,so |
R601 | T611 | T606 | arg2Of | revert,so |
R602 | T606 | T607 | arg1Of | so,that |
R603 | T608 | T609 | arg1Of | they,can |
R604 | T611 | T609 | arg2Of | revert,can |
R605 | T611 | T610 | arg1Of | revert,not |
R606 | T608 | T611 | arg1Of | they,revert |
R607 | T611 | T612 | arg1Of | revert,to |
R608 | T615 | T612 | arg2Of | structure,to |
R609 | T615 | T613 | arg1Of | structure,the |
R610 | T615 | T614 | arg1Of | structure,original |
R611 | T615 | T616 | arg1Of | structure,and |
R612 | T615 | T617 | arg1Of | structure,profound |
R613 | T620 | T617 | arg2Of | prime,profound |
R614 | T617 | T618 | arg1Of | profound,enough |
R615 | T620 | T619 | arg1Of | prime,to |
R616 | T623 | T620 | arg2Of | subunit,prime |
R617 | T623 | T621 | arg1Of | subunit,the |
R618 | T623 | T622 | arg1Of | subunit,S2 |
R619 | T623 | T624 | arg1Of | subunit,for |
R620 | T626 | T624 | arg2Of | fusion,for |
R621 | T626 | T625 | arg1Of | fusion,the |
R622 | T626 | T627 | arg1Of | fusion,of |
R623 | T631 | T627 | arg2Of | membranes,of |
R624 | T631 | T628 | arg1Of | membranes,viral |
R625 | T628 | T629 | arg1Of | viral,and |
R626 | T630 | T629 | arg2Of | cellular,and |
R627 | T631 | T630 | arg1Of | membranes,cellular |
R628 | T634 | T632 | arg1Of | Proteins,Fig. |
R629 | T632 | T633 | arg1Of | Fig.,1 |
R630 | T634 | T635 | arg2Of | Proteins,required |
R631 | T635 | T636 | arg1Of | required,for |
R632 | T639 | T636 | arg2Of | entry,for |
R633 | T639 | T637 | arg1Of | entry,the |
R634 | T639 | T638 | arg1Of | entry,SARS-CoV2-cell |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T10 | 13-17 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T11 | 89-97 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T12 | 132-136 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T13 | 182-194 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T14 | 417-422 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T15 | 477-495 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
T16 | 583-590 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T17 | 753-760 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T18 | 916-934 | Body_part | denotes | cellular membranes | http://purl.org/sig/ont/fma/fma63841 |
T19 | 943-951 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
T20 | 979-983 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T27 | 3-12 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T28 | 122-131 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T29 | 209-213 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T30 | 969-978 | Disease | denotes | SARS-CoV2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T29 | 0-38 | Sentence | denotes | 2 SARS-CoV2 cell entry is not complex |
T30 | 39-143 | Sentence | denotes | Fig. 1 is a schematic illustration of the minimum proteins required to mediate the SARS-CoV2 cell entry. |
T31 | 144-268 | Sentence | denotes | The trimeric, transmembrane spike (S) glycoprotein of the virus, SARS-2-S, includes two main functional subunits: S1 and S2. |
T32 | 269-423 | Sentence | denotes | The former, in turn, consists of the four core domains, S1A, S1B, S1C, and S1D, that contribute to the attachment to the surface receptor of target cells. |
T33 | 424-496 | Sentence | denotes | Then, the latter coordinates the fusion of viral and cellular membranes. |
T34 | 497-591 | Sentence | denotes | Receptor binding activates proteases that can carry out proteolytic cleavage of the S protein. |
T35 | 592-722 | Sentence | denotes | In coronaviruses, cleavage occurs at two sites: the S1/S2 junction and at the S2′, a region close to the viral fusion peptide [2]. |
T36 | 723-935 | Sentence | denotes | Proteolytic cleavage of the S protein causes conformational changes so that they cannot revert to the original structure and profound enough to prime the S2 subunit for the fusion of viral and cellular membranes. |
T37 | 936-990 | Sentence | denotes | Fig. 1 Proteins required for the SARS-CoV2-cell entry. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32413736-26935699-48112965 | 719-720 | 26935699 | denotes | 2 |
T3678 | 719-720 | 26935699 | denotes | 2 |